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arXiv 2025年

作者： Basilone, Riccardo Bruno, Matteo Melo, Hygor Piaget Monteiro Avalle, Michele Loreto, Vittorio Sapienza Univ. of Rome Physics Dept Piazzale A. Moro 2 Rome00185 Italy Sony Computer Science Laboratories - Rome Joint Initiative CREF-SONY Centro Ricerche Enrico Fermi Via Panisperna 89/A Rome00184 Italy Via Panisperna 89/A Rome00184 Italy Postgraduate Program in Applied Informatics University of Fortaleza Ceará Fortaleza60811-905 Brazil Complexity Science Hub Josefstädter Strasse 39 ViennaA 1080 Austria

Active mobility is becoming an essential component of the green transition in modern cities. However, the challenge of designing an efficient network of protected bike lanes without disrupting existing road networks for motorised vehicles remains unsolved. This paper focuses on the specific case of Milan, using a network approach that considers street widths to optimise the placement of dedicated bike lanes at the edges of the network. Unlike other network approaches in this field, our method considers the actual shapes of the streets, which introduces a realistic aspect lacking in current studies. We used these data to simulate cycling networks that maximise connectivity while minimising the impact of bike lane placement on the drivable network. Our mixed simulation strategies optimise for edge betweenness and width. Furthermore, we quantify the impact of dedicated bike lane infrastructure on the existing road network, demonstrating that it is feasible to create highly effective cycling networks with minimal disruption caused by lane width reductions. This paper illustrates how realistic cycling lanes can be simulated using road width data and discusses the challenges and benefits of moving beyond one-dimensional road data in network studies. Copyright © 2025, The Authors. All rights reserved.

关键词： Bicycles

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Towards Safe AI Clinicians: A Comprehensive Study on Large Language Model Jailbreaking in Healthcare

arXiv

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arXiv 2025年

作者： Zhang, Hang Lou, Qian Wang, Yanshan Intelligent Systems Program School of Computing and Information University of Pittsburgh PA United States Department of Computer Science University of Central Florida OrlandoFL United States Department of Health Information Management University of Pittsburgh PA United States Department of Biomedical Informatics University of Pittsburgh PA United States Clinical and Translational Science Institute University of Pittsburgh PittsburghPA United States University of Pittsburgh Medical Center PittsburghPA United States

Large language models (LLMs) are increasingly utilized in healthcare applications. However, their deployment in clinical practice raises significant safety concerns, including the potential spread of harmful information. This study systematically assesses the vulnerabilities of seven LLMs to three advanced black-box jailbreaking techniques within medical contexts. To quantify the effectiveness of these techniques, we propose an automated and domain-adapted agentic evaluation pipeline. Experiment results indicate that leading commercial and open-source LLMs are highly vulnerable to medical jailbreaking attacks. To bolster model safety and reliability, we further investigate the effectiveness of Continual Fine-Tuning (CFT) in defending against medical adversarial attacks. Our findings underscore the necessity for evolving attack methods evaluation, domain-specific safety alignment, and LLM safety-utility balancing. This research offers actionable insights for advancing the safety and reliability of AI clinicians, contributing to ethical and effective AI deployment in healthcare. © 2025, CC BY-NC-SA.

关键词： Patient treatment

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A data-driven approach to discover and quantify systemic lupus erythematosus etiological heterogeneity from electronic health records

arXiv

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arXiv 2025年

作者： Mota, Marco Barbero Still, John M. Gamboa, Jorge L. Strobl, Eric V. Stein, Charles M. Kawai, Vivian K. Lasko, Thomas A. Vanderbilt University Medical Center Department of Biomedical Informatics United States Vanderbilt University Medical Center Department of Medicine United States Vanderbilt University Medical Center Department of Psychiatry and Behavioral Sciences United States Vanderbilt University Medical Center Department of Computer Science United States Vanderbilt DBMI PhD program 2525 West End Ave NashvilleTN United States

Systemic lupus erythematosus (SLE) is a complex heterogeneous disease with many manifestational facets. We propose a data-driven approach to discover probabilistic independent sources from multimodal imperfect EHR data. These sources represent exogenous variables in the data generation process causal graph that estimate latent root causes of the presence of SLE in the health record. We objectively evaluated the sources against the original variables from which they were discovered by training supervised models to discriminate SLE from negative health records using a reduced set of labelled instances. We found 19 predictive sources with high clinical validity and whose EHR signatures define independent factors of SLE heterogeneity. Using the sources as input patient data representation enables models to provide with rich explanations that better capture the clinical reasons why a particular record is (not) an SLE case. Providers may be willing to trade patient-level interpretability for discrimination especially in challenging cases. © 2025, CC BY-NC-ND.

关键词： Electronic health record

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A Multi-phase Deep Learning Approach for Predicting HCC Response to TACE using Complete Computed Tomography

A Multi-phase Deep Learning Approach for Predicting HCC Resp...

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Data science and Engineering in Healthcare, Medicine and Biology, IEEE EMBS Special Topic Conference on

作者： Shun Cheng Chang Chien Fu Liu Marta Misztal Yi Hsien Hsieh Che Lin Graduate Institute of Communication Engineering National Taiwan University (NTU) Taiwan School of Electronic Engineering and Computer Science Queen Mary University of London UK Department of Electrical Engineering NTU Taiwan Center for Computational and Systems Biology and Center for Biotechnology NTU Taiwan Smart Medicine and Health Informatics Program NTU Taiwan

In this research study, we compare the predictive performance of two advanced deep learning-based models in order to provide a solution to TACE (Transarterial Chemoembolization) response prediction in HCC (Hepatocellular Carcinoma) patients. Using entire abdominal CT scans enabled a broader perspective available for the model, eliminating the need for segmentation during the preprocessing. Making use of both single-phase and multi-phase CT imaging, we have used DenseNet121 and have obtained an accuracy of 80% for the multi-phase *** Relevance: The ability to predict the effectiveness of TACE treatment prior to its administration makes it possible to provide a better decision-making aid for physicians and patients.

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Parameter Optimization of Support Vector Regression Using Harris Hawks Optimization

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Procedia computer science 2021年 179卷 17-24页

作者： I Nyoman Setiawan Robert Kurniawan Budi Yuniarto Rezzy Eko Caraka Bens Pardamean Computational Statistics Department Polytechnic of Statistics - STIS Jakarta 13330 Indonesia Department of Information Management College of Informatics Chaoyang University of Technology Taiwan (ROC) Bioinformatics and Data Science Research Center Bina Nusantara University Indonesia 11530 Computer Science Department BINUS Graduate Program - Master of Computer Science Program Bina Nusantara University Jakarta Indonesia. 11530.

Support Vector Regression (SVR) is often used in forecasting. Adjustment of parameters in the SVR affects the results of forecasting. This study aims to analyze the SVR method that is optimized using Harris Hawks Optimization (HHO), hereinafter referred to as HHO-SVR. The HHO-SVR was evaluated using five benchmark datasets to determine the performance of this method. The HHO process is also compared based on the type of kernel and other metaheuristic algorithms. The results showed that the HHO-SVR has almost the same performance as other methods but is less efficient in terms of time. In addition, the type of kernel also affects the process and results.

关键词： SVR harris hawks optimization parameter optimization kernel forecasting

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Digital Forensics Investigation and Incident Response in Internet of Things (IoT-DFIR): Challenges and Models 9

Digital Forensics Investigation and Incident Response in Int...

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9th International Conference on Wireless and Telematics, ICWT 2023

作者： Ahdan, Syaiful Zaki Hamidi, Eki Ahmad Riskiono, Sampurna Dadi Negara, Ridha Muldina Mayasari, Ratna Ramadona, Suci Nurhayati, Ade Sucipto, Adi Jupriyadi Nurkahfi, Galih Nugraha Farahiyah, Dzata Naseer, Muchammad Universitas Teknokrat Indonesia Faculty of Engineering & Computer Science Lampung35132 Indonesia Uin Sunan Gunung Djati Bandung Electrical Engineering Department Bandung40614 Indonesia School of Electrical Engineering Telkom University Bandung40257 Indonesia Elearical Engineering Study Program Politeknik Caltex Riau Riau28265 Indonesia Institut Teknologi Telkom Jakarta Faculty of Engineering Jakarta11710 Indonesia Bandung40135 Indonesia Universitas Islam Indonesia Yogyakarta Faculty of Industrial Technology Yogyakarta55584 Indonesia Sekolah Tinggi Teknologi Bandung Informatics Department Bandung40235 Indonesia

ISBN: (纸本)9798350305029

Many different industries are currently making substantial use of the Internet of Things (IoT). IoT is the process through which electronic devices communicate with their surrounding virtual environment by continuously exchanging data via sensors. Due to increased IoT security concerns, digital forensic investigators now possess greater knowledge and abilities to investigate IoT devices. IoT-DigFor are required in terms of cybercrime due to the rapid growth in the number of electronic devices and the collection and consumption of enormous amounts of data. IoT systems with billions of devices have produced a significant amount of evidence, which presents a significant challenge to digital investigators and practitioners who must connect with IoT devices to conduct fast and thorough investigations into cybercrimes. This article presents detailed information about forensics in the IoT environment. The IoT forensic paradigm and the challenges that design-based security requirements and IoT system security offer for IoT-DigFor are covered in great detail at the beginning of the article. © 2023 IEEE.

关键词： Internet of things

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EXPLANATION BY PROGRESSIVE EXAGGERATION 8

EXPLANATION BY PROGRESSIVE EXAGGERATION

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8th International Conference on Learning Representations, ICLR 2020

作者： Singla, Sumedha Pollack, Brian Chen, Junxiang Batmanghelich, Kayhan Department of Computer Science University of Pittsburgh United States Department of Biomedical Informatics University of Pittsburgh United States Intelligent Systems Program University of Pittsburgh United States

As machine learning methods see greater adoption and implementation in high stakes applications such as medical image diagnosis, the need for model interpretability and explanation has become more critical. Classical approaches that assess feature importance (e.g., saliency maps) do not explain how and why a particular region of an image is relevant to the prediction. We propose a method that explains the outcome of a classification black-box by gradually exaggerating the semantic effect of a given class. Given a query input to a classifier, our method produces a progressive set of plausible variations of that query, which gradually changes the posterior probability from its original class to its negation. These counter-factually generated samples preserve features unrelated to the classification decision, such that a user can employ our method as a "tuning knob" to traverse a data manifold while crossing the decision boundary. Our method is model agnostic and only requires the output value and gradient of the predictor with respect to its input. © 2020 8th International Conference on Learning Representations, ICLR 2020. All rights reserved.

关键词： Semantics

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Vehicular Perception Based on Inertial Sensing: A Structured Mapping of Approaches and Methods

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SN computer science 2020年第5期1卷 1-24页

作者： Menegazzo, Jeferson von Wangenheim, Aldo Graduate Program in Computer Science (PPGCC) Image Processing and Computer Graphics Lab (LAPIX) Department of Informatics and Statistics (INE) Brazilian Institute for Digital Convergence (INCoD) Federal University of Santa Catarina (UFSC) Santa Catarina Florianópolis Brazil

In this paper, we present a structured literature mapping of the state-of-the-art of vehicular perception methods and approaches using inertial sensors. An in-depth investigation and classification were performed employing the results of a systematic literature review. The analysis focused on identifying methods that capture signals provided by inertial sensors such as accelerometers and gyroscopes to recognize transient or persistent events associated with the vehicle’s movement. We classified these events into vehicular exteroception, associated with potholes, cracks, speed bumps, pavement type, conservation state;and vehicular proprioception, associated with lane change, braking, skidding, aquaplaning, turning right or left. Through the comprehensive study of publications in a 7-year time window, in addition to the methods, we have also identified their dependency factors, hardware platforms and applications. © 2020, Springer Nature Singapore Pte Ltd.

关键词： Driver behaviour Driving style Inertial sensors Intelligent transport systems Road conditions Road surface anomaly

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Local Periodicity-Based Beat Tracking for Expressive Classical Piano Music

arXiv

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arXiv 2023年

作者： Chiu, Ching-Yu Müller, Meinard Davies, Matthew E.P. Su, Alvin Wen-Yu Yang, Yi-Hsuan The Graduate Program of Multimedia Systems and Intelligent Computing National Cheng Kung University Academia Sinica Taiwan The International Audio Laboratories Erlangen Germany The Department of Informatics Engineering Centre for Informatics and Systems of the University of Coimbra University of Coimbra Portugal The Department of Computer Science and Information Engineering National Cheng Kung University Taiwan Yating Music Team Taiwan AI Labs Taiwan Research Center for IT Innovation Academia Sinica Taiwan

To model the periodicity of beats, state-of-the-art beat tracking systems use "post-processing trackers" (PPTs) that rely on several empirically determined global assumptions for tempo transition, which work well for music with a steady tempo. For expressive classical music, however, these assumptions can be too rigid. With two large datasets of Western classical piano music, namely the Aligned Scores and Performances (ASAP) dataset and a dataset of Chopin's Mazurkas (Maz-5), we report on experiments showing the failure of existing PPTs to cope with local tempo changes, thus calling for new methods. In this paper, we propose a new local periodicity-based PPT, called predominant local pulse-based dynamic programming (PLPDP) tracking, that allows for more flexible tempo transitions. Specifically, the new PPT incorporates a method called "predominant local pulses" (PLP) in combination with a dynamic programming (DP) component to jointly consider the locally detected periodicity and beat activation strength at each time instant. Accordingly, PLPDP accounts for the local periodicity, rather than relying on a global tempo assumption. Compared to existing PPTs, PLPDP particularly enhances the recall values at the cost of a lower precision, resulting in an overall improvement of F1-score for beat tracking in ASAP (from 0.473 to 0.493) and Maz-5 (from 0.595 to 0.838). © 2023, CC BY.

关键词： Dynamic programming

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Digital Technology in Health Education Trend Mapping through Bibliometrics Analysis

Digital Technology in Health Education Trend Mapping through...

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International Conference on informatics, Multimedia, Cyber and Information System (ICIMCIS)

作者： Fairuz Iqbal Maulana Dian Lestari Vandha Pradwiyasma Widartha Nirwana Haidar Wahyu Dirgantara Computer Science Department School of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Medicine Airlangga University Surabaya Indonesia Information System of Industrial Engineering Faculty Telkom University Bandung Indonesia Informatics Engineering Study Program University of Madura Pamekasan Indonesia Department of Electrical Engineering University of Merdeka Malang Malang Indonesia

ISBN: (纸本)9781665473286

This study examines the mapping of research data on digital technology in the field of health education using bibliometric analysis method. Data was collected by identifying keywords in the Scopus database and sorting them out to sort the studies from the last 10 years (2012–2021). Through this step, a total of 1482 documents were obtained (articles, journals, proceedings, books, and others). The data is then processed using the VOSViewer instrument to obtain a visualization of the mapping analysis. This study also analyzes the network types of authors and co-authors through the VOSViewer instrument. The result of this study indicates that the most document types published within ten years are Articles (66.5%), Review (22.9 % ), Conference Paper (4.2 % ), and others. The most studied subjects are Medicine (55.7%), Nursing (9.0%), Health Professions (8.2%), Social sciences (7.8%), Engineering (3.9%), computer science (2.6 % ), Environmental science (2.6 % ), Biochemistry-Genetics and Molecular Biology (2.2%), Psychology (1.6%), and Dentistry (1.3%). This study offers a written communication process and the nature and direction of developing descriptive means of counting and analyzing the various phases of communication as well as recognizing the authorship and direction of its symptoms in documents on the subject of digital technology in the health sector.

关键词： Training Pediatrics Instruments Education Bibliometrics Transportation Psychology

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