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Hybrid cryptosystem multi-power RSA with N=PmQ and VMPC

IOP Conference Series: Materials science and Engineering 2020年第1期725卷

作者： U Erdiansyah MKM Nasution Sawaluddin Master Program (S2) of Informatics Engineering Faculty of Computer Science and Information Technology University of Sumatera Utara Medan Indonesia Department of Mathematics Faculty of Mathematics and Natural Sciences University of Sumatera Utara Medan Indonesia

In digital world, data and information is very valuable and much targeted by unauthorized parties. One way to secure messages is cryptography. Cryptography itself is a branch of science in concealing messages. In further development a hybrid cryptosystem was formed which combines symmetrical and asymmetric cryptography, which in this paper uses VMPC and Multi-Power.. The RSA Multi-Power algorithm is an asymmetric algorithm that is excellent at message encryption but requires a long process time because it uses very complicated calculations. While VMPC has advantages in the process with fast time and relatively small size of ciphertext. Here we have analyzed the performance of various variants of RSA that have been hybridized with VMPC and given the results.

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Combination of 3des with dct algorithm in message security

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IOP Conference Series: Materials science and Engineering 2020年第1期725卷

作者： S. Guntur MKM Nasution RW Nasution Master Program (S2) of Informatics Engineering Faculty of Computer Science and Information Technology University of Sumatera Utara Medan Indonesia Department of Mathematics Faculty of Mathematics and Natural Sciences University of Sumatera Utara Medan Indonesia

In the digital era, communication through computer networks plays an important role. Through electronic communication, a person can make transactions or communication very quickly and practically. Sending data / messages from one place to another is much constrained by the issue of confidentiality. There are many ways you can hide data / messages that will be sent. First, using cryptographic techniques, namely by encoding data / messages using certain algorithms. Another technique is to insert a message that will be sent to other media, so that the message will be hidden and what will appear is other media used to insert *** will be performed a Performance Analysis of the Combination of 3DES and DCT Algorithms in Securing Message Files into the Image.

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GREGoR: Accelerating Genomics for Rare Diseases

arXiv

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arXiv 2024年

作者： Dawood, Moez Heavner, Ben Wheeler, Marsha M. Ungar, Rachel A. LoTempio, Jonathan Wiel, Laurens Berger, Seth Bernstein, Jonathan A. Chong, Jessica X. Délot, Emmanuèle C. Eichler, Evan E. Gibbs, Richard A. Lupski, James R. Shojaie, Ali Talkowski, Michael E. Wagner, Alex H. Wei, Chia-Lin Wellington, Christopher Wheeler, Matthew T. Carvalho, Claudia M.B. Gifford, Casey A. May, Susanne Miller, Danny E. Rehm, Heidi L. Sedlazeck, Fritz J. Vilain, Eric O'Donnell-Luria, Anne Posey, Jennifer E. Chadwick, Lisa H. Bamshad, Michael J. Montgomery, Stephen B. Human Genome Sequencing Center Baylor College of Medicine HoustonTX United States Department of Molecular and Human Genetics Baylor College of Medicine HoustonTX United States Medical Scientist Training Program Baylor College of Medicine HoustonTX United States Department of Biostatistics University of Washington SeattleWA United States Department of Genetics School of Medicine Stanford University StanfordCA United States Department of Pathology School of Medicine Stanford University Stanford CA United States Stanford Center for Biomedical Ethics School of Medicine Stanford University Stanford CA United States Institute for Clinical and Translational Science University of California IrvineCA United States Division of Cardiovascular Medicine School of Medicine Stanford University Stanford CA United States Division of Genetics and Metabolism Children’s National Rare Disease Institute WashingtonDC United States Center for Genetic Medicine Research Children’s National Rare Disease Institute WashingtonDC United States Department of Genomics and Precision Medicine George Washington University WashingtonDC United States Department of Pediatrics School of Medicine Stanford University Stanford CA United States Department of Pediatrics Dvision of Genetic Medicine University of Washington SeattleWA United States Brotman Baty Institute for Precision Medicine University of Washington SeattleWA United States Department of Genome Sciences University of Washington SeattleWA United States Howard Hughes Medical Institute University of Washington SeattleWA United States Department of Pediatrics Baylor College of Medicine HoustonTX United States Center for Genomic Medicine Massachusetts General Hospital BostonMA United States Program in Medical and Population Genetics Broad Institute of MIT and Harvard BostonMA United States Department of Neurology Massachusetts General Hospital Harvard Medical School BostonMA United States Stanley Center for

Rare diseases are collectively common, affecting approximately one in twenty individuals worldwide. In recent years, rapid progress has been made in rare disease diagnostics due to advances in DNA sequencing, development of new computational and experimental approaches to prioritize genes and genetic variants, and increased global exchange of clinical and genetic data. However, more than half of individuals suspected to have a rare disease lack a genetic diagnosis. The Genomics Research to Elucidate the Genetics of Rare Diseases (GREGoR) Consortium was initiated to study thousands of challenging rare disease cases and families and apply, standardize, and evaluate emerging genomics technologies and analytics to accelerate their adoption in clinical practice. Further, all data generated, currently representing ~7500 individuals from ~3000 families, is rapidly made available to researchers worldwide via the Genomic Data science Analysis, Visualization, and informatics Lab-space (AnVIL) to catalyze global efforts to develop approaches for genetic diagnoses in rare diseases (https://***/data). The majority of these families have undergone prior clinical genetic testing but remained unsolved, with most being exome-negative. Here, we describe the collaborative research framework, datasets, and discoveries comprising GREGoR that will provide foundational resources and substrates for the future of rare disease genomics. © 2024, CC BY.

关键词： Genome

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Automatic Extraction of Medication Mentions from Tweets-Overview of the BioCreative VII Shared Task 3 Competition

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Database : the journal of biological databases and curation 2023年第2023期2023卷 baac108页

作者： Davy Weissenbacher Karen O'Connor Siddharth Rawal Yu Zhang Richard Tzong-Han Tsai Timothy Miller Dongfang Xu Carol Anderson Bo Liu Qing Han Jinfeng Zhang Igor Kulev Berkay Köprü Raul Rodriguez-Esteban Elif Ozkirimli Ammer Ayach Roland Roller Stephen Piccolo Peijin Han V G Vinod Vydiswaran Ramya Tekumalla Juan M Banda Parsa Bagherzadeh Sabine Bergler João F Silva Tiago Almeida Paloma Martinez Renzo Rivera-Zavala Chen-Kai Wang Hong-Jie Dai Luis Alberto Robles Hernandez Graciela Gonzalez-Hernandez Department of Computational Biomedicine Cedars-Sinai Medical Center Los Angeles CA USA. DBEI The Perelman School of Medicine University of Pennsylvania Philadelphia PA USA. Department of Computer Science and Information Engineering National Central University No. 300 Zhongda Rd Zhongli District Taoyuan 320 Taiwan. IoX Center National Taiwan University Da'an District Section 4 Roosevelt Rd No. 1 Barry Lam Hall Taipei 106 Taiwan. Research Center for Humanities and Social Sciences Academia Sinica No. 128 Section 2 Academia Rd Nangang District Taipei 115 Taiwan. Computational Health Informatics Program Boston Children's Hospital Boston MA USA. Department of Pediatrics Harvard Medical School Boston MA USA. NVIDIA Santa Clara CA USA. Department of Statistics Florida State University Tallahassee FL USA. Data and Analytics Chapter F. Hoffmann-La Roche Ltd Switzerland. Pharmaceutical Research and Early Development Roche Innovation Center Basel Switzerland. Speech and Language Technology Lab DFKI Berlin Germany. Department of Biology Brigham Young University Provo UT USA. Department of Computational Medicine and Bioinformatics Medical School University of Michigan Ann Arbor MI USA. Department of Learning Health Sciences Medical School University of Michigan Ann Arbor MI USA. School of Information University of Michigan Ann Arbor MI USA. Department of Computer Science Georgia State University Atlanta GA USA. CLaC Labs Concordia University Montreal Canada. DETI Institute of Electronics and Informatics Engineering of Aveiro University of Aveiro Portugal. Department of Computation University of A Coruña Spain. Computer Science and Engineering Department Universidad Carlos III de Madrid Madrid Spain. Big Data Laboratory Chunghwa Telecom Laboratories Taoyuan Taiwan. Department of Computer Science National Yang Ming Chiao Tung University Hsinchu Taiwan. Department of Electrical Engineering College of Electrical Engineering and Computer Sci

This study presents the outcomes of the shared task competition BioCreative VII (Task 3) focusing on the extraction of medication names from a Twitter user's publicly available tweets (the user's 'timeline'). In general, detecting health-related tweets is notoriously challenging for natural language processing tools. The main challenge, aside from the informality of the language used, is that people tweet about any and all topics, and most of their tweets are not related to health. Thus, finding those tweets in a user's timeline that mention specific health-related concepts such as medications requires addressing extreme imbalance. Task 3 called for detecting tweets in a user's timeline that mentions a medication name and, for each detected mention, extracting its span. The organizers made available a corpus consisting of 182 049 tweets publicly posted by 212 Twitter users with all medication mentions manually annotated. The corpus exhibits the natural distribution of positive tweets, with only 442 tweets (0.2%) mentioning a medication. This task was an opportunity for participants to evaluate methods that are robust to class imbalance beyond the simple lexical match. A total of 65 teams registered, and 16 teams submitted a system run. This study summarizes the corpus created by the organizers and the approaches taken by the participating teams for this challenge. The corpus is freely available at https://***/tasks/biocreative-vii/track-3/. The methods and the results of the competing systems are analyzed with a focus on the approaches taken for learning from class-imbalanced data.

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Dynamic laplace: Efficient centrality measure for weighted or unweighted evolving networks

arXiv

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arXiv 2018年

作者： Cordeiro, Mário Sarmento, Rui Portocarrero Brazdil, Pavel Gama, João Doctoral Program in Informatics Engineering Faculty of Engineering University of Porto INESC TEC - Institute for Systems and Computer Engineering Technology and Science

With its origin in sociology, Social Network Analysis (SNA), quickly emerged and spread to other areas of research, including anthropology, biology, information science, organizational studies, political science, and computer science. Being it's objective the investigation of social structures through the use of networks and graph theory, Social Network Analysis is, nowadays, an important research area in several domains. Social Network Analysis cope with different problems namely network metrics, models, visualization and information spreading, each one with several approaches, methods and algorithms. One of the critical areas of Social Network Analysis involves the calculation of different centrality measures (i.e.: the most important vertices within a graph). Today, the challenge is how to do this fast and efficiently, as many increasingly larger datasets are available. Recently, the need to apply such centrality algorithms to non static networks (i.e.: networks that evolve over time) is also a new challenge. Incremental and dynamic versions of centrality measures are starting to emerge (betweenness, closeness, etc). Our contribution is the proposal of two incremental versions of the Laplacian Centrality measure, that can be applied not only to large graphs but also to, weighted or unweighted, dynamically changing networks. The experimental evaluation was performed with several tests in different types of evolving networks, incremental or fully dynamic. Results have shown that our incremental versions of the algorithm can calculate node centralities in large networks, faster and efficiently than the corresponding batch version in both incremental and full dynamic network setups. Copyright © 2018, The Authors. All rights reserved.

关键词： Laplace transforms

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Traffic sign detection using histogram of oriented gradients and max margin object detection

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Journal of Physics: Conference Series 2019年第1期1230卷

作者： Reinaldo Natanael Manurung Juara immanuel Simbolon Christnatalis Informatics Engineering Study Program Deparment of Technology and Computer Science Universitas Prima Indonesia Medan Indonesia

Traffic signs are important markers in two-wheeled and four-wheeled vehicles. However, there is a change in direction or arrangement on the road that cannot be opened on a map which can cause incorrect information, which can cause traffic jams. In this journal the author uses a camera mounted on a car that provides a solution for drivers who issue problems that occur on the road that show directions or arrangements that are not directly updated using the HOG and MMOD methods. HOGs and MMODs are methods that can refute objects well, and move images and will be recognized immediately. The information received can be sent directly to an electronic map so that it can be accessed automatically by the driver's information and assistance and other information finds the right path, so that it can help the driver and can avoid traffic jams.

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Analysis A parallel combination between the Number Theorists aRe Us, Riverst Shamir Adleman and Triple Data Encryption Standard methods for measuring the speed of document security

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Journal of Physics: Conference Series 2019年第1期1230卷

作者： Luken Candawan Hardiaman Hulu William David Sipayung Muhammad Hafis Christnatalis Informatics Engineering Study Program Deparment of Technology and Computer Science Universitas Prima Indonesia Medan Indonesia

computer security is a very important thing in an information system. The strength of the NTRU algorithm is the difficulty of finding a short vector of a lattice (a discrete subgroup of a collection of vectors that includes the entire vector environment) of a random polynomial that has a large degree. The strength of the RSA algorithm lies in the level of difficulty in factoring non-prime numbers into the primary factor. As long as no efficient algorithm has been found to find the prime factors of large integers, the RSA algorithm is highly recommended for message encryption. And finally this is the TRIPEL DES algorithm designed using a 56-bit key, and that size is enough to run a secure encryption technique. This algorithm provides a simple solution that is running the DES Algorithm 3 times for data blocks. The results of our study of measuring speed on encryption and decryption using the same file are superior to the RSA algorithm compared to the NTRU and TRIPLE DES algorithms.

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Measurement of activeness lecturers in SmartLecturer based learning using fuzzy Mamdani and Sugeno

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IOP Conference Series: Materials science and Engineering 2020年第1期725卷

作者： Sfenrianto Sfenrianto Muhammad Yasin Kaman Nainggolan Mesra Betty Yel Information Systems Management Department BINUS Graduate Program – Master of Information Systems Management Bina Nusantara University Jakarta Indonesia 11480 Informatics Management Politeknik LP3I Jakarta Indonesia 10450 Master of Computer Science - Postgraduate Programs STMIK Nusa Mandiri Faculty of Computer Science STIKOM CKI Jakarta Indonesia

The success of learning in a classroom that uses supporting media demands lecturer activity. The level of activity of lecturers in class and using learning media such as Smart lecturer can be measured using a fuzzy logic approach. This study aims to measure the level of active lecturers using the approach, namely: Mamdani and Sugeno method. Stages of lecturer activity measurement by forming a fuzzy set, composition rules as many as 24 rules and the defuzzification process using the centroid method that produces the level of activity of each is low, medium and high. Based on 173 lecturer activity data, the results of the Mamdani method indicates low 66%, medium 31%, and high 3%. While the Sugeno method produces a level of activity low 75%, moderate 17%, and high 8%. Therefore, Mamdani method is more suitable for the calculation because the spread of results is relatively evenly distributed at each level.

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A Neuro-Inspired Approach to Solve a Simultaneous Location and Mapping Task Using Shared Information in Multiple Robots Systems 15

A Neuro-Inspired Approach to Solve a Simultaneous Location a...

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15th International Conference on Control, Automation, Robotics and Vision, ICARCV 2018

作者： Menezes, Matheus Chaves De Freitas, Edison Pignaton Cheng, Sen De Oliveira, Alexandre Cesar Muniz De Almeida Ribeiro, Paulo Rogerio Graduate Program on Computer Science Federal University of Maranhão Sao Luis Brazil Computational Neuroscience Ruhr University Bochum Institute for Neural Computation Bochum Germany Department of Informatics Federal University of Maranhão Sao Luis Maranhao Brazil Department of Computer Engineering Federal University of Maranhão Sao Luis Maranhao Brazil

ISBN: (纸本)9781538695821

This paper presents a neuro-inspired mapping approach that uses partial information shared by multiple robots to reduce the time to create a map of an entire environment. Robots using a neurobiologically inspired algorithm, namely RatSLAM, map an environment sharing video information among themselves. RatSLAM, which is based on the navigation system present in the hippocampus of rodents' brain, has been widely used on simultaneous localization and mapping (SLAM) problem. This proposal has been able to generate suitable maps mainly when there is redundant information, e.g. a scene is seen more than once, since this fact activates local view cells that inject activity inside the pose cells via an excitatory link. The work here reported extends this approach by merging partial information acquired by multiple robots. The results from the performed experiments show that the final map built by two robots with shared information is similar to one built by two robots performing the same mapping task individually, i.e. without sharing information. However, the time spent to generate the whole map with the proposed shared approach was smaller than the one without the shared information. Thus, the current approach allows creating a complete map of an environment within a reduced time using multiple robots. © 2018 IEEE.

关键词： Mapping

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ThermalProGAN: A sequence-based thermally stable protein generator trained using unpaired data

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Journal of bioinformatics and computational biology 2023年第1期21卷 2350008页

作者： Hui-Ling Huang Chong-Heng Weng Torbjörn E M Nordling Yi-Fan Liou International Program of Health Informatics and Management College of Management Chang Gung University No. 259 Wenhua 1st Road Guishan District Taoyuan City 33302 Taiwan. Department of Computer Science and Information Engineering National Central University No. 300 Zhongda Road Zhongli District Taoyuan City 320317 Taiwan. Department of Mechanical Engineering National Cheng Kung University No. 1 University Road Tainan City 701 Taiwan. Department of Applied Physics and Electronics Umeå University 90187 Umeå Sweden. Department of Virtual-Reality Interaction with Artificial Intelligence Technology Coretronic Reality Incorporation No. 5 Wenhua Rd. Hukou Township Hsinchu County 303 Taiwan.

MOTIVATION:The synthesis of proteins with novel desired properties is challenging but sought after by the industry and academia. The dominating approach is based on trial-and-error inducing point mutations, assisted by structural information or predictive models built with paired data that are difficult to collect. This study proposes a sequence-based unpaired-sample of novel protein inventor (SUNI) to build ThermalProGAN for generating thermally stable proteins based on sequence information. RESULTS:The ThermalProGAN can strongly mutate the input sequence with a median number of 32 residues. A known normal protein, 1RG0, was used to generate a thermally stable form by mutating 51 residues. After superimposing the two structures, high similarity is shown, indicating that the basic function would be conserved. Eighty four molecular dynamics simulation results of 1RG0 and the COVID-19 vaccine candidates with a total simulation time of 840[Formula: see text]ns indicate that the thermal stability increased. CONCLUSION:This proof of concept demonstrated that transfer of a desired protein property from one set of proteins is feasible. The source code of ThermalProGAN can be freely accessed at https://***/markliou/ThermalProGAN/ with an MIT license. The website is https://***:433. Supplementary data are available on Github.

关键词： CycleGAN Protein synthesis generative adversarial neural network thermal stability

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