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Application of Graph-Curvature Features in Auxiliary Diagnosis for Histopathological Image Identification of Gastric Cancer

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SSRN

SSRN 2023年

作者： He, Ruilin Li, Chen Yang, Xinyi Yang, Jinzhu Jiang, Tao Grzegorzek, Marcin Sun, Hongzan Microscopic Image and Medical Image Analysis Group College of Medicine and Biological Information Engineering Northeastern University Shenyang China Key Laboratory of Intelligent Computing in Medical Image Ministry of Education Northeastern University Liaoning Shenyang China School of Intelligent Medicine Chengdu University of Traditional Chinese Medicine Chengdu China International Joint Institute of Robotics and Intelligent Systems Chengdu University of Information Technology Chengdu China Institute for Medical Informatics University of Luebeck Luebeck Germany Department of Knowledge Engineering University of Economics in Katowice Katowice Poland Shengjing Hospital of China Medical University Shenyang China School of Computer Science and Engineering

Background: Histopathology diagnosis is often regarded as the final diagnostic method for malignant tumors, but it has some drawbacks. This paper explores a computer-aided diagnostic method that can identify benign and malignant gastric cancer with histopathology images. Method: This article obtains the most suitable process through multiple experiments, compared multiple methods and features for classification. Firstly, the U-net is applied to segment the image. Next, the nucleus is extracted from the segmented image and the Minimum Spanning Tree (MST) diagram structure is drawn. The third step is to extract the graph-curvature features of histopathology image according to the MST image. Finally, by inputting graph-curvature features into the classifier, the recognition results for benign or malignant can be obtained. Result: During the experiment, we use various methods for comparison. In the image segmentation stage, U-net, watershed algorithm and Otsu threshold segmentation methods are used respectively. Combined with multiple indicators, we find that the U-net method is the most suitable for segmentation of histopathology images. In the feature extraction stage, in addition to extracting graph-edge feature and graph-curvature feature, several basic image features are also extracted, including Red, Green, Blue feature, Gray-Level Co-occurrence Matrix feature, Histogram of Oriented Gradient feature, and Local Binary Pattern feature. In the classifier design stage, we experimented with various methods, such as Support vector machine (SVM), Random forest, Artificial Neural Network, K Nearest Neighbors, VGG-16 and Inception-V3. Through the comparison and analysis, the classification results with an accuracy of 98.57% can be obtained by inputting the graph-curvature feature into SVM classifier. Conclusion: This paper has created a unique feature, graph-curvature feature based on MST to represent and analyze histopathology images. This graph-based feature can be used

关键词： Local binary pattern

One to many: Adaptive instrument segmentation via meta learning and dynamic online adaptation in robotic surgical video

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arXiv 2021年

作者： Zhao, Zixu Jin, Yueming Lu, Bo Ng, Chi-Fai Dou, Qi Liu, Yun-Hui Heng, Pheng-Ann The Department of Computer Science and Engineering The Chinese University of Hong Kong Hong Kong The T Stone Robotics Institute The Department of Mechanical and Automation Engineering The Chinese University of Hong Kong Hong Kong Guangdong-Hong Kong-Macao Joint Laboratory of Human-Machine Intelligence-Synergy Systems Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences China The Department of Surgery The Chinese University of Hong Kong Hong Kong

Surgical instrument segmentation in robot-assisted surgery (RAS) - especially that using learning-based models - relies on the assumption that training and testing videos are sampled from the same domain. However, it is impractical and expensive to collect and annotate sufficient data from every new domain. To greatly increase the label efficiency, we explore a new problem, i.e., adaptive instrument segmentation, which is to effectively adapt one source model to new robotic surgical videos from multiple target domains, only given the annotated instruments in the first frame. We propose MDAL, a meta-learning based dynamic online adaptive learning scheme with a two-stage framework to fast adapt the model parameters on the first frame and partial subsequent frames while predicting the results. MDAL learns the general knowledge of instruments and the fast adaptation ability through the video-specific meta-learning paradigm. The added gradient gate excludes the noisy supervision from pseudo masks for dynamic online adaptation on target videos. We demonstrate empirically that MDAL outperforms other state-of-the-art methods on two datasets (including a real-world RAS dataset). The promising performance on ex-vivo scenes also benefits the downstream tasks such as robot-assisted suturing and camera control. Copyright © 2021, The Authors. All rights reserved.

关键词： Surgical equipment

AutoPET Challenge: Combining nn-Unet with Swin UNETR Augmented by Maximum Intensity Projection Classifier

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arXiv 2022年

作者： Heiliger, Lars Marinov, Zdravko Hasin, Max Ferreira, André Fragemann, Jana Pomykala, Kelsey Murray, Jacob Kersting, David Alves, Victor Stiefelhagen, Rainer Egger, Jan Kleesiek, Jens Institute for Ai in Medicine University Hospital Essen Essen Germany University Medicine Essen Essen Germany Institute for Anthropomatics and Robotics Karlsruhe Institute of Technology Karlsruhe Germany Center Algoritmi University of Minho Braga Portugal Computer Algorithms for Medicine Laboratory Graz Austria Department of Nuclear Medicine University Hospital Essen Essen Germany Essen Germany West German Cancer Center Essen Germany HIDSS4Health - Helmholtz Information Data Science School for Health Heidelberg Karlsruhe Germany

Tumor volume and changes in tumor characteristics over time are important biomarkers for cancer therapy. In this context, FDGPET/CT scans are routinely used for staging and re-staging of cancer, as the radiolabeled fluorodeoxyglucose is taken up in regions of high metabolism. Unfortunately, these regions with high metabolism are not specific to tumors and can also represent physiological uptake by normal functioning organs, inflammation, or infection, making detailed and reliable tumor segmentation in these scans a demanding task. This gap in research is addressed by the AutoPET challenge, which provides a public data set with FDG-PET/CT scans from 900 patients to encourage further improvement in this field. Our contribution to this challenge is an ensemble of two state-of-the-art segmentation models, the nn-Unet and the Swin UNETR, augmented by a maximum intensity projection classifier that acts like a gating mechanism. If it predicts the existence of lesions, both segmentations are combined by a late fusion approach. Our solution achieves an average Cross Validation Dice score of 72.12% on patients diagnosed with lung cancer, melanoma, and lymphoma in our cross-validation. Code: https://***/heiligerl/AutoPET-Challenge-Submission. © 2022, CC BY.

关键词： Tumors

On embodied visual navigation in real environments through Habitat

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arXiv 2020年

作者： Rosano, Marco Furnari, Antonino Gulino, Luigi Farinella, Giovanni Maria FPV@IPLAB Department of Mathematics and Computer Science University of Catania Italy Cognitive Robotics and Social Sensing Laboratory ICAR-CNR Palermo Italy OrangeDev s.r.l. Firenze Italy

Visual navigation models based on deep learning can learn effective policies when trained on large amounts of visual observations through reinforcement learning. Unfortunately, collecting the required experience in the real world requires the deployment of a robotic platform, which is expensive and time-consuming. To deal with this limitation, several simulation platforms have been proposed in order to train visual navigation policies on virtual environments efficiently. Despite the advantages they offer, simulators present a limited realism in terms of appearance and physical dynamics, leading to navigation policies that do not generalize in the real world. In this paper, we propose a tool based on the Habitat simulator which exploits real world images of the environment, together with sensor and actuator noise models, to produce more realistic navigation episodes. We perform a range of experiments to assess the ability of such policies to generalize using virtual and real-world images, as well as observations transformed with unsupervised domain adaptation approaches. We also assess the impact of sensor and actuation noise on the navigation performance and investigate whether it allows to learn more robust navigation policies. We show that our tool can effectively help to train and evaluate navigation policies on real-world observations without running navigation episodes in the real world. Copyright © 2020, The Authors. All rights reserved.

关键词： Ecosystems

P-WAE: Generalized patch-wasserstein autoencoder for anomaly screening

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arXiv 2021年

作者： Zhang, Hui Chen, Yurong Wang, Yaonan Cao, Yihong Wu, Q.M. Jonathan Yang, Yimin National Engineering Laboratory of Robot Visual Perception and Control Technology School of Robotics Hunan University Changsha Hunan410082 China Department of Electrical and Computer Engineering University of Windsor WindsorONN9B3P4 Canada Department of Computer Science Lakehead University OntarioP7B 5E1 Canada Vector Institute TorontoM5G 1M1 Canada

To mitigate the inspector’s workload and improve the quality of the product, computer vision-based anomaly detection (AD) techniques are gradually deployed in real-world industrial scenarios. Recent anomaly analysis benchmarks progress to generative models. The aim is to model the defect-free distribution so that anomalies can be classified as out-of-distribution samples. Nevertheless, there are two disturbing factors that need researchers and deployers to prioritize: (i) the simplistic prior latent distribution inducing limited expressive capability;(ii) the collapsed mutual-dependent features resulting in poor generalization. In this paper, we propose a novel Patch-wise Wasserstein AutoEncoder (P-WAE) architecture to alleviate those challenges. In particular, a patch-wise variational inference model coupled with solving the jigsaw puzzle is designed, which is a simple yet effective way to increase the expressiveness and complexity of the latent manifold. This alleviates the blurry reconstruction problem. In addition, the Hilbert-Schmidt Independence Criterion (HSIC) bottleneck is introduced to constrain the over-regularization representation. Comprehensive experiments, conducted on the MVTec AD dataset, demonstrate the superior performance of our proposed method. © 2021, CC BY.

关键词： Anomaly detection

Continuous signed distance computation for polygonal robots in 3D

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Continuous signed distance computation for polygonal robots ...

2019 International Conference on robotics and Automation, ICRA 2019

作者： Lee, Youngeun Kheddar, Abderrahmane Kim, Young J. Department of Computer Science and Engineering Ewha Womans University Seoul Korea Republic of CNRS-AIST Joint Robotics Laboratory Tsukuba Japan CNRS-University of Montpellier LIRMM IDH Team Montpellier France

We propose a novel method adaptive subdivision (AS) to evaluate the distance function for moving general polygonal models. The distance function can have a positive and a negative value, each of which corresponds to the Euclidean distance and penetration depth, respectively. In our approach, the distance between a pair of objects can be evaluated along any time interval of the object's trajectory;therefore it is called continuous, and a minimum of the continuous distance (MCD) is determined for collision avoidance. In order to compute a MCD for general polygonal models, we calculate the upper and lower bounds of the distance in the time interval and abandons the time intervals that cannot realize the MCD. We have implemented our distance evaluation method, and have experimentally validated the proposed methods to effectively and accurately find the MCDs to generate a collision-free motion for the HRP-2 humanoid robot. © 2019 IEEE.

关键词： Anthropomorphic robots

Projected Sliced Wasserstein Autoencoder-based Hyperspectral Images Anomaly Detection

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arXiv 2021年

作者： Chen, Yurong Zhang, Hui Wang, Yaonan Wu, Q. M. Jonathan Yang, Yimin National Engineering Laboratory of Robot Visual Perception and Control Technology School of Robotics Hunan University Hunan Changsha410082 China Department of Electrical and Computer Engineering University of Windsor WindsorONN9B3P4 Canada Department of Computer Science Lakehead University ONP7B 5E1 Canada Vector Institute TorontoONM5G 1M1 Canada

Anomaly detection refers to identifying the observation that deviates from the normal pattern, which has been an active research area in various domains. Recently, the increasing data scale, complexity, and dimension turns the traditional representation and statistical-based outlier detection method into challenging. In this paper, we leverage the generative model in hyperspectral images anomaly detection. The gist is to model the distribution of the normal data, while the out-of-distribution sample can be viewed as the outlier. At first, the variational inference-based anomaly detection methods are investigated. We theoretically and empirically find that they are unstable due to the strong notion of distance (f-divergence) served as the regularization. Secondly, this paper introduces sliced Wasserstein distance, which is a weaker distribution measure compared with f-divergence. However, the number of randomly slicing poses a difficulty to estimate the true distance. In the end, we propose a projected sliced Wasserstein (PSW) autoencoder-based anomaly screening method. In particular, we leverage a computation-friendly eigen-decomposition method to find the principal component as slicing the high-dimensional data. Furthermore, our proposed distance can be calculated with the closed-form, even the prior distribution is not Gaussian. Comprehensive experiments conducted on various real-world hyperspectral anomaly detection benchmarks demonstrate the superior performance of our proposed method. © 2021, CC BY.

关键词： Spectroscopy

Pareto Continual Learning: Preference-Conditioned Learning and Adaption for Dynamic Stability-Plasticity Trade-off

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arXiv 2025年

作者： Lai, Song Zhao, Zhe Zhu, Fei Lin, Xi Zhang, Qingfu Meng, Gaofeng Department of Computer Science City University of Hong Kong Hong Kong Centre for Artificial Intelligence and Robotics HK Institute of Science & Innovation Chinese Academy of Sciences China State Key Laboratory of Multimodal Artificial Intelligence Systems Institute of Automation Chinese Academy of Sciences China School of Artificial Intelligence University of Chinese Academy of Sciences China City University of Hong Kong Shenzhen Research Institute Hong Kong University of Science and Technology of China China

Continual learning aims to learn multiple tasks sequentially. A key challenge in continual learning is balancing between two objectives: retaining knowledge from old tasks (stability) and adapting to new tasks (plasticity). Experience replay methods, which store and replay past data alongside new data, have become a widely adopted approach to mitigate catastrophic forgetting. However, these methods neglect the dynamic nature of the stability-plasticity trade-off and aim to find a fixed and unchanging balance, resulting in suboptimal adaptation during training and inference. In this paper, we propose Pareto Continual Learning (ParetoCL), a novel framework that reformulates the stability-plasticity trade-off in continual learning as a multi-objective optimization (MOO) problem. ParetoCL introduces a preference-conditioned model to efficiently learn a set of Pareto optimal solutions representing different trade-offs and enables dynamic adaptation during inference. From a generalization perspective, ParetoCL can be seen as an objective augmentation approach that learns from different objective combinations of stability and plasticity. Extensive experiments across multiple datasets and settings demonstrate that ParetoCL outperforms state-of-the-art methods and adapts to diverse continual learning scenarios. Copyright © 2025, The Authors. All rights reserved.

关键词： Multi-task learning

Variable Stiffness Control with Strict Frequency Domain Constraints for Physical Human-Robot Interaction

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arXiv 2020年

作者： Zou, Wulin Duan, Pu Chen, Yawen Yu, Ningbo Shi, Ling Department of Electronic and Computer Engineering Hong Kong University of Science and Technology Hong Kong Hong Kong Xeno Dynamics Co. Ltd Shenzhen China Institute of Robotics and Automatic Information Systems Tianjin Key Laboratory of Intelligent Robotics Nankai University Tianjin China

Variable impedance control is advantageous for physical human-robot interaction to improve safety, adaptability and many other aspects. This paper presents a gain-scheduled variable stiffness control approach under strict frequency-domain constraints. Firstly, to reduce conservativeness, we characterize and constrain the impedance rendering, actuator saturation, disturbance/noise rejection and passivity requirements into their specific frequency bands. This relaxation makes sense because of the restricted frequency properties of the interactive robots. Secondly, a gain-scheduled method is taken to regulate the controller gains with respect to the desired stiffness. Thirdly, the scheduling function is parameterized via a nonsmooth optimization method. Finally, the proposed approach is validated by simulations, experiments and comparisons with a gain-fixed passivity-based PID method. Copyright © 2020, The Authors. All rights reserved.

关键词： Frequency domain analysis