During the multistep process of metastasis,cancer cells encounter various mechanical forces which make them deform *** accurate in-silico models,capable of simulating the interactions between the mechanical forces and...
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During the multistep process of metastasis,cancer cells encounter various mechanical forces which make them deform *** accurate in-silico models,capable of simulating the interactions between the mechanical forces and highly deformable cancer cells,can pave the way for the development of novel diagnostic and predictive methods for metastatic ***-network models of cancer cell,empowered by our recently proposed identification approach,promises a versatile numerical tool for developing experimentally validated models that can simulate complex interactions at cellular *** this numerical tool,we presented spring-network models of breast cancer cells that can accurately replicate the experimental data of deformation behavior of the cells flowing in a fluidic domain and passing narrow constrictions comparable to ***,using high-speed imaging,we experimentally studied the deformability of breast cancer cell lines with varying metastatic potential(MCF-7(less invasive),SKBR-3(medium-high invasive),and MDA-MB-231(highly invasive)in terms of their entry time to a constricted microfluidic *** observed that MDA-MB-231,that has the highest metastatic potential,is the most deformable cell among the ***,by focusing on this cell line,experimental measurements were expanded to two more constricted microchannel *** experimental deformability data in three constricted microchannel sizes for various cell sizes,enabled accurate identification of the unknown parameters of the spring-network model of the breast cancer cell line(MDA-MB-231).Our results show that the identifed parameters depend on the cell size,suggesting the need for a systematic procedure for identifying the size-dependent parameters of spring-network models of *** the numerical results show,the presented cell models can simulate the entry process of the cell into constricted channels with very good agreements with the measured experimen
Cardiovascular diseases (CVDs), a leading cause of global mortality, are intricately linked to arterial stiffness, a key factor in cardiovascular health. Non-invasive assessment of arterial stiffness, particularly thr...
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We propose dynamic modulations of a photonic molecule to achieve topological properties of light. We investigate the Hall transport in synthetic dimensions and the system modulation strategy to demonstrate the pumping...
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Recently, there have been some attempts of Transformer in 3D point cloud classification. In order to reduce computations, most existing methods focus on local spatial attention,but ignore their content and fail to est...
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Recently, there have been some attempts of Transformer in 3D point cloud classification. In order to reduce computations, most existing methods focus on local spatial attention,but ignore their content and fail to establish relationships between distant but relevant points. To overcome the limitation of local spatial attention, we propose a point content-based Transformer architecture, called PointConT for short. It exploits the locality of points in the feature space(content-based), which clusters the sampled points with similar features into the same class and computes the self-attention within each class, thus enabling an effective trade-off between capturing long-range dependencies and computational complexity. We further introduce an inception feature aggregator for point cloud classification, which uses parallel structures to aggregate high-frequency and low-frequency information in each branch separately. Extensive experiments show that our PointConT model achieves a remarkable performance on point cloud shape classification. Especially, our method exhibits 90.3% Top-1 accuracy on the hardest setting of ScanObjectN N. Source code of this paper is available at https://***/yahuiliu99/PointC onT.
Renewable energy generation sources (RESs) are gaining increased popularity due to global efforts to reduce carbon emissions and mitigate effects of climate change. Planning and managing increasing levels of RESs, spe...
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We propose the engineering of the Berry curvature in optical resonator networks by exploiting long-range hopping. By generalizing the Hofstadter model, we examine the effect of hopping orders for the design of topolog...
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The use of interactive tools, such as voice assistants and social robots, holds promise as coaching aids during public speaking rehearsals. To create a coach that is both effective and likable, it is important to unde...
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The ability to capture fine spectral discriminative information enables hyperspectral images(HSIs) to observe, detect and identify objects with subtle spectral discrepancy. However, the captured HSIs may not represent...
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The ability to capture fine spectral discriminative information enables hyperspectral images(HSIs) to observe, detect and identify objects with subtle spectral discrepancy. However, the captured HSIs may not represent the true distribution of ground objects and the received reflectance at imaging instruments may be degraded, owing to environmental disturbances, atmospheric effects, and sensors' hardware limitations. These degradations include but are not limited to complex noise, heavy stripes, deadlines,cloud/shadow occlusion, blurring and spatial-resolution degradation, etc. These degradations dramatically reduce the quality and usefulness of HSIs. Low-rank tensor approximation(LRTA) is such an emerging technique, having gained much attention in the HSI restoration community, with an ever-growing theoretical foundation and pivotal technological innovation. Compared to low-rank matrix approximation(LRMA),LRTA characterizes more complex intrinsic structures of high-order data and owns more efficient learning abilities, being established to address convex and non-convex inverse optimization problems induced by HSI restoration. This survey mainly attempts to present a sophisticated, cutting-edge, and comprehensive technical survey of LRTA toward HSI restoration, specifically focusing on the following six topics: denoising, fusion,destriping, inpainting, deblurring, and super-resolution. For each topic, state-of-the-art restoration methods are introduced, with quantitative and visual performance assessments. Open issues and challenges are also presented, including model formulation, algorithm design, prior exploration, and application concerning the interpretation requirements.
The sixth generation (6G) mobile wireless networks are expected to provide massive ultra-reliable and low-latency communications (mURLLC) for data services, which require extremely stringent quality-of-services (QoS) ...
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