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Computing mRNA and protein statistical moments for a renewal model of stochastic gene-expression

Computing mRNA and protein statistical moments for a renewal...

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IEEE Annual Conference on Decision and Control

作者： Duarte Antunes Abhyudai Singh Hybrid and Networked Systems Group Department of Mechanical Engineering Eindhoven University of Technology the Netherlands Department of Electrical and Computer Engineering Biomedical Engineering and Mathematical Sciences University of Delaware Newark DE U.S.A.

ISBN: (纸本)9781467357159

The level of a given mRNA or protein exhibits significant variations from cell-to-cell across a homogenous population of living cells. Much work has focused on understanding the different sources of noise in the gene-expression process that drive this stochastic variability in gene-expression. Recent experiments tracking growth and division of individual cells reveal that cell division times have considerable intercellular heterogeneity. Here we investigate how randomness in the cell division times can create variability in population counts. We consider a model where mRNA/protein levels evolve according to a linear differential equation with cell divisions times spaced by independent and identically distributed random intervals. Whenever the cell divides the population of mRNA and protein is halved. Considering gamma distributed cell division intervals, we provide a method for computing the mean and variance of mRNA and protein levels and provide exact analytical formulas for the asymptotic values of these statistical moments. Computation of the statistical moments for physiologically relevant parameter values shows that randomness in the cell division process can be a major factor in driving difference in protein levels across a population of cells.

关键词： Proteins Differential equations Protein engineering Sociology Statistics Stochastic processes Mathematical model

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On the optimal placement of underwater sensors in a tree shaped multi-hop hierarchical network

On the optimal placement of underwater sensors in a tree sha...

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Annual Conference on Information Sciences and systems (CISS)

作者： Hadis Dashtestani Paul Cotae Ira S. Moskowitz Department of Electrical and Computer Engineering School of Engineering and Applied Science University of District of Columbia Washington DC DC USA Naval Research Laboratory Center for High Assurance Computer Systems Washington DC DC USA

We analyze the optimal location of underwater acoustic sensor nodes, with respect to the capacity of the wireless links between the nodes, in a multi-hop hierarchical tree structure based on the information each node has to transfer between underwater levels. A novel algorithm is proposed to calculate the optimal distances between sensor nodes for the proposed hierarchical network. Numerical results for different channel conditions; such as an ideal channel, an imperfect channel with a certain BER, and a channel with interference, are provided. In addition, our algorithm is used to obtain the optimal frequency for each level in the tree shaped network for the above-mentioned conditions.

关键词： Sensors Wireless sensor networks Acoustics Interference Topology Wireless communication Network topology

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Thermal modelling of a high speed permanent magnet synchronous machine

Thermal modelling of a high speed permanent magnet synchrono...

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International Electric Machines & Drives Conference

作者： Andre J. Grobler S. Robert Holm George van Schoor School for Electrical Electronic and Computer Engineering Northwest University Potchefstroom South Africa Council for Scientific and Industrial Research Mobile Intelligent Autonomous Systems Group Pretoria South Africa

The thermal behavoir of permanent magnet synchronous machines (PMSMs) is important since overheating of the permanent magnets can lead to demagnetization. This article gives an overview of a hybrid thermal model for a high speed PMSM which combines lumped parameter and analytical models. The losses found in a slotless PMSM are also discussed since they are the heat sources. An overview of the experiments performed to determine some of the thermal parameters and verify the models are also given. It is shown that bearing loss can make a significant contribution to the thermal behavior of a machine.

关键词： PMSM modelling magnet

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Optical flow switching: An end-to-end “UltraFlow” architecture

Optical flow switching: An end-to-end “UltraFlow” architec...

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International Conference on Transparent Optical Networks

作者： Vincent W.S. Chan Lei Zheng Henna Huang Guy Weichenberg Anurupa Ganguly Claude E. Shannon Communication and Network Group Research Laboratory of Electronics Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology USA

We describe the design of an optical network architecture that will satisfy dramatic increases in data rate demands of emerging applications. Optical flow switching (OFS), will enable significant rate growth of > 10 3 , with power-efficiency and cost-effective scalability of next-generation networks. We will describe architecture concepts germinated 24 years ago, technology and testbed demonstrations performed in the last 19 years, and the architecture construct from the Physical Layer to the Transport Layer of an implementable optical flow switching network that is scalable and manageable. Recent architecture for an NSF-funded Internet research Program “UltraFlow”, for which OFS can be used, will be described.

关键词： Optical fiber networks Integrated optics Optical switches computer architecture High-speed optical techniques Wide area networks Local area networks

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Best Relay Selection in Cooperative Spectrum Sharing systems with Multiple Primary Users

Best Relay Selection in Cooperative Spectrum Sharing Systems...

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IEEE International Conference on Communications

作者： F. R. V. Guimaraes D. B. da Costa M. Benjillali T. A. Tsiftsis G. K. Karagiannidis Wireless Telecommunications Research Group (GTEL) Federal University of Ceará (UFC) CE Brazil Communications Systems Department INPT Rabat Morocco Department of Electrical Engineering Technological Educational Institute of Lamia Lamia Greece Department of Electrical & Computer Engineering Aristotle University of Thessaloniki Thessaloniki Greece

Cooperative spectrum sharing systems (CSSSs) have recently received considerable attention from the wireless community due to their performance gains and spectrum utilization improvement when compared to traditional communication systems. Owing to this fact, we investigate the outage performance of CSSSs in the presence of multiple primary users (PUs). The secondary user (SU) network is composed by one source node, N decode-and-forward (DF) relays, and one destination. A best relay selection strategy is performed where the selected relay is that which maximizes the end-to-end signal-to-noise ratio (SNR) and, simultaneously, satisfies the interference constraint imposed by the M PU receivers. The communication between the SU source and SU destination is carried out through the help of one out of N DF relays and also via direct link. Afterwards, the SU destination selects the best path between the direct and the relaying path by using selection combining technique. A closed-form expression for the outage probability (OP) is derived, and an asymptotic analysis is carried out which reveals that the diversity order of the considered system equals N + 1, showing that it is not affected neither by the number of PU receivers nor by the interference threshold. The presented analytical expressions are corroborated by means of Monte Carlo simulations and insightful discussions are provided.

关键词： Relays Receivers Signal to noise ratio Fading Wireless communication Interference constraints

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Amplification of terahertz radiation by plasmons in graphene with a planar Bragg grating

Amplification of terahertz radiation by plasmons in graphene...

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6th International Conference on Advanced Optoelectronics and Lasers, CAOL 2013

作者： Polischuk, O.V. Popov, V.V. Nikitov, S.A. Ryzhii, V. Otsuji, T. Shur, M.S. Russian Academy of Sciences Saratov 410019 Russia Saratov State University Saratov 410012 Russia Kotelnikov Institute of Radio Engineering and Electronics Russian Academy of Sciences Mokhovaya 11-7 Moscow 125009 Russia Research Institute for Electrical Communication Tohoku University Sendai 980-8577 Japan Department of Electrical Computer and Systems Engineering Rensselaer Polytechnic Institute Troy NY 12180 United States

ISBN: (纸本)9781479900183

The giant amplification of terahertz radiation due to stimulated generation of plasmons in graphene with a planar Bragg grating strongly coupled to terahertz radiation is predicted. The amplification of terahertz wave at the plasmon resonance frequencies is several orders of magnitude stronger than away from the resonances. It is shown that the dynamic and frequency ranges of terahertz graphene amplifier can be strongly enhanced in the structure with a narrow-slit Bragg grating and/or thin barrier layer. © 2013 IEEE.

关键词： Amplification

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Random threshold graphs with exponential fitness: The width of the phase transition for connectivity

Random threshold graphs with exponential fitness: The width ...

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IEEE International Symposium on Information Theory

作者： Armand M. Makowski Osman Yagğan Department of Electrical and Computer Engineering Institute for Systems Research University of Maryland College Park MD USA Carnegie Mellon University Pittsburgh PA US

We consider random threshold graphs where the fitness variables are exponentially distributed. Simulations show that the zero-one law for graph connectivity exhibits a sharp phase transition. We formalize this observa... 详细信息

关键词： Manganese Educational institutions Exponential distribution Information theory Convergence

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Wind Power Effect and Control in Hydro-Quebec electrical Network

Wind Power Effect and Control in Hydro-Quebec Electrical Net...

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International Conference on Modelling, Identification & Control

作者： H. Mehrjerdi D. Asber S. Lefebvre M. Saad Research Institute of Hydro-Quebec Power Systems and Mathematics Varennes QUE Canada Department of Electrical and Computer Engineering Quebec University Montreal QUE Canada

The increasing amount of wind power in power system needs more attention particularly in voltage regulation. This paper presents a control strategy based on model predictive control that tries to regulate the voltage which is disturbed by wind power. In this paper, control algorithm is applied to Hydro-Quebec electrical network. Furthermore, disturbances are intentionally inserted to some loads to verify the performance of control algorithm to violation and wind power in the same time. The results show the performance and ability of controller.

关键词： Model predictive voltage control Transmission system Wind plant

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Slotted polyimide-aerogel-filled-waveguide arrays

Slotted polyimide-aerogel-filled-waveguide arrays

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IEEE International Symposium on Antennas and Propagation

作者： R. A. Rodriguez-Solis H. L. Pacheco F. A. Miranda M. A. B. Meador Department of Electrical and Computer Engineering University of Puerto Rico Antennas and Optical Systems Branch Durability and Protective Coatings Branch NASA Glenn Research Center

ISBN: (纸本)9781467353168

Polyimide aerogels were considered to serve as a filling for millimeter-wave waveguides. While these waveguides present a slightly higher loss than hollow waveguides, they have less losses than Duroid substrate integrated waveguides (less than 0.15 dB at Ka-band, in a 20 mm section), and exhibit an order of magnitude of mass reduction when compared to commercial waveguides. A Ka-band slotted aerogel-filled-waveguide array was designed, which provided the same gain (9 dBi) as its standard waveguide counterpart, and a slotted aerogel-filled-waveguide array using folded-slots was designed for comparison, obtaining a gain of 9 dB and a bandwidth of 590 MHz.

关键词： Waveguide Device Component SLOT Hollow waveguides Gain Bandwidth substrate integrated waveguides Duroid Extremely high frequencies arrays dubnium decibel

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Observer-based stabilization of uncertain linear systems with recycle: An LMI approach

Observer-based stabilization of uncertain linear systems wit...

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European Control Conference (ECC)

作者： Miguel Parada Daniel Sbarbaro Renato A. Borges Pedro L. D. Peres Control Systems Group of the Technische Universität Berlin Berlin Germany Department of Electrical Engineering Universidad de Concepcion Concepcion Chile Department of Electrical Engineering University of Brasilia - UnB Brasilia-DF Brazil School of Electrical and Computer Engineering University of Campinas SP Brazil

ISBN: (纸本)9781479901890

This paper deals with the control of processes having recycle streams. These processes can be modeled as state delayed systems. In this work the problem of robust design of an observed-based controller for these systems is presented. The system is assumed to have norm-bounded uncertainties which are independent in every matrix involved in its state space realization. To ensure asymptotic stability of the closed loop system, a Lyapunov functional is used to obtain delay-independent design conditions. The controller design is accomplished by means of a convex optimization procedure formulated using linear matrix inequalities (LMIs). Numerical examples are provided to illustrate the main characteristics of the proposed design method.

关键词： Recycling Linear matrix inequalities Uncertainty Symmetric matrices Vectors Observers Process control

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