This article presents a parameter study on the applied game theory in Genetic Algorithm (GA), performing an analysis of the game Prisoner's Dilemma applied in the solution of four constrained engineering problems....
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This article presents a parameter study on the applied game theory in Genetic Algorithm (GA), performing an analysis of the game Prisoner's Dilemma applied in the solution of four constrained engineering problems. Simulations were applied in four different variations of the game, in order to find the best configuration for the analyzed problems. Then, after obtaining the best configuration of the game, we performed an analysis of the incidence of Alpha and Beta weights, present in GA fitness with Social Interaction, using the game that best suited each problem, employing sixteen different weight configurations. At end, the results obtained authenticated the influence of the Social Interaction process in the essence of GA.
QIIME 2 is a completely re-engineered microbiome bioinformatics platform based on the popular QIIME platform, which it has replaced. QIIME 2 facilitates comprehensive and fully reproducible microbiome data science, im...
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Data mining is routinely used to organize ensembles of short temporal observations so as to reconstruct useful, low-dimensional realizations of an underlying dynamical system. In this paper, we use manifold learning t...
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N-Acyl lipids are important mediators of several biological processes including immune function and stress response. To enhance the detection of N-acyl lipids with untargeted mass spectrometry-based metabolomics, we c...
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N-Acyl lipids are important mediators of several biological processes including immune function and stress response. To enhance the detection of N-acyl lipids with untargeted mass spectrometry-based metabolomics, we created a reference spectral library retrieving N-acyl lipid patterns from 2,700 public datasets, identifying 851 N-acyl lipids that were detected 356,542 times. 777 are not documented in lipid structural databases, with 18% of these derived from short-chain fatty acids and found in the digestive tract and other organs. Their levels varied with diet and microbial colonization and in people living with diabetes. We used the library to link microbial N-acyl lipids, including histamine and polyamine conjugates, to HIV status and cognitive impairment. This resource will enhance the annotation of these compounds in future studies to further the understanding of their roles in health and disease and to highlight the value of large-scale untargeted metabolomics data for metabolite discovery.
The following topics are dealt with: Internet; organisational aspects; data analysis; educational institutions; information systems; knowledge management; statistical analysis; further education; computer aided instru...
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The following topics are dealt with: Internet; organisational aspects; data analysis; educational institutions; information systems; knowledge management; statistical analysis; further education; computer aided instruction; business data processing.
Reporting-Guidelines in Medicine play an important role in promoting the quality of reports in health-related research. For instance, a poorly reported research may induce misinterpretation and inappropriate clinical ...
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