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Synthesis and Second-Order Nonlinear Optical Properties of New Coumaromethacrylate-Methylmethacrylate Copolymers

MRS Online Proceedings Library 2011年第1期173卷 601-606页

作者： R. A. Henry J. M. Hoover A. Knoesen S. T. Kowel G. A. Lindsay M. A. Mortazavi Research Department Chemistry Division China Lake USA Department of Electrical Engineering and Computer Science Organized Research Program on Polymeric Ultrathin Film Systems University of California Davis USA

The synthesis and second-order nonlinear optical (NLO) properties of a new family of optically nonlinear coumarin dye-containing polymers is reported. Polymerizable coumaromethacrylate (CMA) monomers having various alkyl spacers (C2 to C5) between the polymerizable group and the chromophore were prepared and copolymerized with methylmethacrylate (MMA) and other vinyl monomers. The CMA copolymers had high chromophoric content (up to 18 × 1020) and glass transitions as high as 132°C. Spin cast films were prepared on BK7 substrates and oriented by corona-onset poling at elevated temperatures (COPET). The poled CMA copolymer films were characterized for spectroscopic absorption and second harmonic properties. A comparison of the nonlinear optical properties of poled CMA-MMA copolymers to poled guest-host systems is made. Relative to guest/host systems, CMA-MMA copolymer films exhibit larger and much more stable second-order nonlinear optical properties.

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Ranking docked models of protein-protein complexes using predicted partner-specific protein-protein interfaces: A preliminary study 11

Ranking docked models of protein-protein complexes using pre...

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2011 ACM Conference on Bioinformatics, Computational Biology and Biomedicine, ACM-BCB 2011

作者： Xue, Li C. Jordan, Rafael A. El-Manzalawy, Yasser Dobbs, Drena Honavar, Vasant Bioinformatics and Computational Biology Program Iowa State University Ames IA 50011 United States Department of Genetics Development and Cell Biology Iowa State University Ames 50011 United States Department of Computer Science Iowa State University Ames IA 50011 United States Department of Computer Science Pontificia Universidad Javeriana Cali Colombia Department of Systems and Computer Engineering AI-Azhar University Cairo Egypt

ISBN: (纸本)9781450307963

Computational protein-protein docking is a valuable tool for determining the conformation of complexes formed by interacting proteins. Selecting near-native conformations from the large number of possible models generated by docking software presents a significant challenge in practice. We introduce a novel method for ranking docked conformations based on the degree of overlap between the interface residues of a docked conformation formed by a pair of proteins with the set of predicted interface residues between them. Our approach relies on a method, called PS-HomPPI, for reliably predicting proteinprotein interface residues by taking into account information derived from both interacting proteins. PS-HomPPI infers the residues of a query protein that are likely to interact with a partner protein based on known interface residues of the homo-interologs of the query-partner protein pair, i.e., pairs of interacting proteins that are homologous to the query protein and partner protein. Our results on Docking Benchmark 3.0 show that the quality of the ranking of docked conformations using our method is consistently superior to that produced using ClusPro cluster-size-based and energy-based criteria for 61 out of the 64 docking complexes for which PS-HomPPI produces interface predictions. An implementation of our method for ranking docked models is freely available at: http://***/DockRank/. Copyright © 2011 ACM.

关键词： Proteins

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Automatic Generation of Balletic Motions

Automatic Generation of Balletic Motions

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IEEE/ACM International Conference on Cyber-Physical systems (ICCPS)

作者： Amy LaViers Magnus Egerstedt Yushan Chen Calin Belta School of Electrical and Computer Engineering Georgia Institute of Technology Atlanta GA USA Department of Electrical and Computer Engineering Boston University Boston MA USA Department of Mechanical Engineering Division of Systems Engineering and the Bioinformatics Graduate Program Boston University MA USA

As cyber-physical systems become more prevalent, specifications for these systems must be formulated in a more nuanced manner. This paper presents a particular instantiation of such specification by proposing a framework that endows robotic motions with a sense of aesthetic style. Drawing inspiration from classical ballet, poses are cast as discrete states and movements as the transitions between these states. Thus, a given movement style is encoded in the availability of transitions at each state, and the dynamics of a complex physical trajectory are abstracted as a system which moves between these states. Using Linear Temporal Logic (LTL), we are able to further constrain the set of possible sequences through the transition system and thus prevent it from evolving through a sequence of states that is physically impossible or aesthetically undesirable. Our overarching objective is to facilitate subtle degrees of control over systems as such subtleties are required, more and more, to interact in a social and aesthetically driven world.

关键词： Automata Leg Legged locomotion Humans Trajectory Hip

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Validation of a Device for Fluorescence Sensing of Rare Circulating Cells with Diffusive Light in an Optical Flow Phantom Model

Validation of a Device for Fluorescence Sensing of Rare Circ...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Eric Zettergren Dwayne Vickers Judith Runnels Charles P. Lin Mark J. Niedre Department of Electrical and Computer Engineering Northeastern University Department of Chemical Engineering Northeastern University Advanced Microscopy Program Center for Systems Biology and Wellman Center for Photomedicine Massachusetts General Hospital

ISBN: (纸本)9781424441211

Detection and quantification of rare circulating cells in biological tissues is an important problem and has many applications in biomedical research. Current methods normally involve extraction of blood samples and counting of cells ex vivo, or the use of microscopy-based fluorescence in vivo flow cytometry. The goal of this work is to develop an instrument for non-invasively enumerating very rare circulating cells in small animals with diffuse light with several orders of magnitude sensitivity improvement versus current approaches. In this work, we describe the design of our system and show that single, fluorescent microspheres can be detected in limb-mimicking optical flow phantoms with varying optical properties chosen to simulate in vivo conditions. Further, we demonstrate single cell counting capabilities using fluorescently (Vybrant-DiD) labeled Jurkat and Multiple Myeloma cells. Ongoing work includes in vivo testing and characterization of our system in mice.

关键词： Imaging Phantom Optic Flow Cell Count diffuse light in vivo test Optical properties TISSUES (BIOLOGY) EX-VIVO Fluorescence Myeloma cell blood specimen

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A parallel architecture for ray-tracing with an embedded intersection algorithm

A parallel architecture for ray-tracing with an embedded int...

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IEEE International Symposium on Circuits and systems (ISCAS)

作者： Alexandre S. Nery Nadia Nedjah Felipe M.G. França Lech Jozwiak LAM-Computer Architecture and Microelectronics Laboratory Systems Engineering and Computer Science Program COPPE Universidade Federal do Rio de Janeiro Brazil Department of Electrical Engineering-Electronic Systems Eindhovan University of Technology Netherlands Department of Electronics Engineering and Telecommunications-Faculty of Engineering Universidade do Estado do Rio de Janeiro (UERJ) Brazil

Real time rendering of three-dimensional scenes in Ray Tracing is a hard problem. However, parallel implementations have been enabling real time performance, as the algorithm can be highly parallelized. Thus, a custom parallel design in hardware is likely to achieve a good performance. In this paper, we further improve the GridRT architecture overall performance by embedding the ray-triangle intersection computation into the precessing elements that form the architecture. Low cost and high rendering performance are the main concerns in this novel design. The results show that the execution time of each intersection computation is reduced by at least 50%, while the area cost is practically unchanged or even reduced when compared to the original GridRT implementation.

关键词： Ray tracing Registers Equations USA Councils Mathematical model Parallel architectures

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MLEA： A Solution for Users of Android in UTPVirtual

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computer Technology and Application 2011年第5期2卷 406-412页

作者： Gisela Torres de Clunie Sergio Crespo Coelho da Silva Pinto Aris Linet Castillo Lucas Monteiro Braz Tasia Serrao Norman Rangel Jeanette Riley Olinda de Barraza Kexy Rodriguez Computer Systems Engineering Department Technological University of Panama Panama 0819 Panama Computer Science Research and Graduate Program in Applied Computing University of the Sinos Valley （UNISINOS） RS 93022-000 Brazil CIDITIC Technological University of Panama Panama 0819 Panama

This paper describes a design of an educational platform for a mobile learning architecture, which is a state of the an topic in distance education. The product will allow users to interact in an efficient, flexible, and transparent fashion with a web-based education environment, in this case Module Object-Oriented Dynamic Learning Environment （Moodle）, using Android mobile devices. In order to provide a strong and lasting architecture, the Service Oriented Architecture （SOA） methodology is used given that it allows easy software re-utilization as well as integration of heterogeneous services. The architecture is based on web services implemented with Representational State Transfer （REST）, as it has been demonstrated to be lighter and less consuming than other protocols, for devices with limited resources such as mobile devices. Web services provide the communication means between the server side and the client side of the architecture, whereas agents are used to deliver the services itself. The authors propose the development of an environment that facilitates the integration of various educational resources to support m-learning. An important aspect of the proposal is the offering of a tool to provide customized alerts for students and teachers, enabling them to remain updated about activities taking place in the courses.

关键词： Distance learning virtual education m-learning service oriented architecture （SOA） mobile learning mobile computing interoperability representational state transfer （REST）.

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Combined Physician-Parent Decision Support tool for the neonatal intensive care unit

Combined Physician-Parent Decision Support tool for the neon...

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IEEE International Workshop on Medical Measurement and Applications (MEMEA)

作者： Monique Frize Erika Bariciak Sandra Dunn Sabine Weyand Jeff Gilchrist Stuart Tozer Department Systems and Computer Engineering School of Information Technology & Engineering Carleton University Ottawa Canada School of Information Technology & Engineering University of Ottawa Ottawa Canada Department Systems and Computer Engineering Carleton University Ottawa Canada Division of Neonatology Childrens Hospital Eastern Ontario Ottawa Canada Champlain Maternal Newborn Regional Program (CMNRP) Greece

In this paper we explore the design options for the development of a combined physician-parent decision support tool for a neonatal intensive care unit (NICU), known as PPADS or Physician and Parent Decision Support. The work incorporates previous research on the development of a clinical data repository and the development of an NICU clinical decision support system (CDSS) for physicians that predicts mortality and a number of potential complications. In this work, we are combining the physician and parent tools to develop a system designed to facilitate parents' involvement in the shared decision-making process for difficult treatment decisions for their critically ill babies in the NICU. We have described the framework and architectural design for developing the combined physician-parent tool. We identified the design criteria and mode of operation, as well as the standards that apply to this type of decision system. We also explored the existing open-source technologies that would best fit this type of design. Finally, we have developed a prototype of the system that was evaluated by our physician partner and a nurse decision support specialist. Future work will involve a pilot usability study in a tertiary level NICU.

关键词： Pediatrics Estimation Decision making Prototypes Terminology Hospitals

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Visualization of complex data relationships and maps: Using the BLOOM platform to provide business insights 11

Visualization of complex data relationships and maps: Using ...

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Proceedings of the 12th International Conference on computer systems and Technologies

作者： Horsfall, Frank Tanev, Stoyan Bontchev, Boyan Gigilev, Todor Gruev, Angel Program Dep. of Systems and Computer Engineering Carleton University Ottawa ON Canada Dep. of Technology and Innovation University of Southern Denmark OIdense M DK 5230 Denmark Dep. of Software Engineering Sofia University St. Kl. Ohridski 5 J. Bourchier Blv. Sofia BG 1164 Bulgaria FMI-Sofia University Bulgaria

ISBN: (纸本)9781450309172

Modern information visualization in focussed on new methods for visual mappings and novel strategies for interaction and navigation through various types of view of a visual form. The paper presents the Bloom platform for visualization of complex networks with highly related entities and aggregations, both able to possess complex data attributes. It discusses two case studies assessing the scalability of the tool by creating a visualization of the large, complex networks - one of Ottawa Centre for Research and Innovation, containing data of approximately 1,900 companies aggregated within a cluster hierarchy, and another of Danish companies' cluster. There are presented various visualization layouts of the company network and a representation of some company data properties over Google maps. © 2011 ACM.

关键词： Visualization

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Porantim-Opt: Optimizing the Combined Selection of Model-Based Testing Techniques

Porantim-Opt: Optimizing the Combined Selection of Model-Bas...

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IEEE International Conference on Software Testing Verification and Validation Workshop, ICSTW

作者： Arilo Claudio Dias Neto Rosiane de Freitas Rodrigues Guilherme Horta Travassos Computer Science Department Federal University of Amazonas Manaus Brazil Systems Engineering and Computer Science Program-COPPE Federal University of Rio de Janeiro Rio de Janeiro Rio de Janeiro Brazil

The combination of testing techniques is considered an effective strategy to evaluate a software product. However, the selection of which techniques to combine in a software project has been an interesting challenge in the Software engineering field. This paper presents a proposal extending an approach developed to support the combined selection of model-based testing (MBT) techniques, named Porantim, applying Multiobjective Combinatorial Optimization strategy by determining the smallest dominating set in a bipartite and weighted graph. Thus, a local search strategy algorithm is proposed generating solutions aiming at maximizing the coverage of software project characteristics and skills required by the testing team to use the techniques and minimizing the eventual effort to construct models used for test cases generation. A preliminary evaluation analyzes this new approach when compared to the Porantim's original version, and the results indicate improvements in the MBT techniques selection.

关键词： Software Testing Analytical models Software engineering Optimization programming Search problems

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Hardware Reuse in Modern Application-Specific Processors and Accelerators

Hardware Reuse in Modern Application-Specific Processors and...

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Euromicro Symposium on Digital System Design

作者： Alexandre S. Nery Lech Jozwiak Menno Lindwer Mauro Cocco Nadia Nedjah Felipe M.G. Franca LAM-Computer Architecture and Microelectronics Laboratory Systems Engineering and Computer Science Program COPPE Universidade Federal do Rio de Janeiro Brazil Department of Electrical Engineering-Electronic Systems Eindhoven University of Technology Netherlands Silicon Hive-Intel UMG Netherlands Department of Electronics Engineering and Telecommunications-Faculty of Engineering Universidade do Estado do Rio de Janeiro Brazil

Effective exploitation of the application-specific parallel patterns and computation operations through their direct implementation in hardware is the base for construction of high-quality application-specific (re-)configurable application specific instruction set processors (ASIPs) and hardware accelerators for modern highly-demanding applications. Although it receives a lot of attention from the researchers and practitioners, a very important problem of hardware reuse in ASIP and accelerator synthesis is clearly underestimated and does not get enough attention in the published research. This paper is an effect of an industry and academic collaborative research. It analyses the problem of hardware sharing, shows its high practical relevance, as well as a big influence of hardware sharing on the major circuit and system parameters, and its importance for the multi-objective optimization and tradeoff exploitation. It also demonstrates that the state-of-the-art synthesis tools do not sufficiently address this problem and gives several guidelines related to enhancement of the hardware reuse.

关键词： Hardware Resource management computer architecture Optimization program processors Adders Delay

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