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Abstracts from the 3rd International Genomic Medicine Conference (3rd IGMC 2015) : Jeddah, Kingdom of Saudi Arabia. 30 November - 3 December 2015

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BMC genomics 2016年第6期17 Suppl 6卷 487页

作者： Jerry W. Shay Noriko Homma Ruyun Zhou Muhammad Imran Naseer Adeel G. Chaudhary Mohammed Al-Qahtani Nobutaka Hirokawa Maryam Goudarzi Albert J. Fornace Saleh Baeesa Deema Hussain Mohammed Bangash Fahad Alghamdi Hans-Juergen Schulten Angel Carracedo Ishaq Khan Hanadi Qashqari Nawal Madkhali Mohamad Saka Kulvinder S. Saini Awatif Jamal Jaudah Al-Maghrabi Adel Abuzenadah Adeel Chaudhary Mohammed Al Qahtani Ghazi Damanhouri Heba Alkhatabi Anne Goodeve Laura Crookes Nikolas Niksic Nicholas Beauchamp Adel M. Abuzenadah Jim Vaught Bruce Budowle Mourad Assidi Abdelbaset Buhmeida Leena Merdad Sudhir Kumar Sayaka Miura Karen Gomez Mahmood Rasool Ahmed Rebai Sajjad Karim Hend F. Nour Eldin Heba Abusamra Elham M. Alhathli Nada Salem Mohammed H. Al-Qahtani Hossam Faheem Ashok Agarwa Eberhard Nieschlag Joachim Wistuba Oliver S. Damm Mohd A. Beg Taha A. Abdel-Meguid Hisham A. Mosli Osama S. Bajouh Serdar Coskun Muhammad Abu-Elmagd Ashraf Dallol Sahar Hakamy Wejdan Al-Qahtani Asia Al-Harbi Shireen Hussain Burak Ozkosem Rick DuBois Safia S. Messaoudi Maryam T. Dandana Touhami Mahjoub Wassim Y. Almawi S. Abdalla M. Nabil Al-Aama Asmaa Elzawahry Tsuyoshi Takahashi Sachiyo Mimaki Eisaku Furukawa Rie Nakatsuka Isao Kurosaka Takahiko Nishigaki Hiromi Nakamura Satoshi Serada Tetsuji Naka Seiichi Hirota Tatsuhiro Shibata Katsuya Tsuchihara Toshirou Nishida Mamoru Kato Sajid Mehmood Naeem Mahmood Ashraf Awais Asif Muhammad Bilal Malik Siddique Mehmood Aadil Hussain Qazi Mohammad Sajid Jamal Mughees Uddin Siddiqui Mohammad A. Alzohairy Mohammad A. Al Karaawi Taoufik Nedjadi Heba Al-Khattabi Adel Al-Ammari Ahmed Al-Sayyad Hédia Zitouni Nozha Raguema Marwa Ben Ali Wided Malah Raja Lfalah Wassim Almawi Mohammed Elanbari Andrey Ptitsyn Sana Mahjoub Rabeb El Ghali Bechir Achour Nidhal Ben Amor Brahim N’siri Hamid Morjani Esam Azhar Vera Chayeb Maryam Dendena Hedia Zitouni Khedija Zouari-Limayem Bassem Refaat Ahmed M. Ashshi Sarah A. Batwa Hazem Ramadan Amal Awad Ahmed Ateya Adel Galal Ahmed El-Shemi Ahmad Ashshi Mohammed Basalamah Youjin Na Cha University of Texas Southwestern Medical Center Dallas USA Department of Cell Biology and Anatomy Graduate School of Medicine the University of Tokyo Tokyo Japan Center of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Department of Biochemistry and Molecular & Cellular Biology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Oncology Lombardi Comprehensive Cancer Center Georgetown University Washington USA Department of Radiation Medicine Lombardi Comprehensive Cancer Center Georgetown University Washington USA Center of Excellence in Genomic Medicine Research (CEGMR) King Abdulaziz University Jeddah Kingdom of Saudi Arabia King Fahd Medical Research Centre King Abdulaziz University Jeddah Saudi Arabia Centre of Excellence in Genomic Medicine Research King Abdulaziz University Jeddah Saudi Arabia Sheffield Diagnostic Genetic Service Sheffield Children’s NHS Foundation Trust Western Bank Sheffield UK Center of Innovations in Personalized Medicine King Abdulaziz University Jeddah Saudi Arabia President ISBER Editor-in-Chief Biopreservation & Biobanking ᅟ USA Institute of Applied Genetics Department of Molecular and Medical Genetics University of North Texas Health Science Center Fort Worth USA Department of Dental Public Health Faculty of Dentistry King Abdulaziz University Jeddah Saudi Arabia Institute for Genomics and Evolutionary Medicine Temple University Philadelphia USA Center of Excellence in Genomic Medicine King Abdulaziz University Jeddah Kingdom of Saudi Arabia Laboratory of Molecular and Cellular Screening Processes (Bioinformatics Group) Centre of Biotechnology of Sfax Sfax Tunisia Fujitsu Technology Solutions International ᅟ ᅟ Case Western Reserve University School of Medicine and Lerner College of Medicine Cleveland Clinic Foundation Cleveland USA American Center for Reproductive Medicine Andrology Center Cleveland USA Center for Reproductive Medicine and

O1 Regulation of genes by telomere length over long distances Jerry W. Shay O2 The microtubule destabilizer KIF2A regulates the postnatal establishment of neuronal circuits in addition to prenatal cell survival, cell migration, and axon elongation, and its loss leading to malformation of cortical development and severe epilepsy Noriko Homma, Ruyun Zhou, Muhammad Imran Naseer, Adeel G. Chaudhary, Mohammed Al-Qahtani, Nobutaka Hirokawa O3 Integration of metagenomics and metabolomics in gut microbiome research Maryam Goudarzi, Albert J. Fornace Jr. O4 A unique integrated system to discern pathogenesis of central nervous system tumors Saleh Baeesa, Deema Hussain, Mohammed Bangash, Fahad Alghamdi, Hans-Juergen Schulten, Angel Carracedo, Ishaq Khan, Hanadi Qashqari, Nawal Madkhali, Mohamad Saka, Kulvinder S. Saini, Awatif Jamal, Jaudah Al-Maghrabi, Adel Abuzenadah, Adeel Chaudhary, Mohammed Al Qahtani, Ghazi Damanhouri O5 RPL27A is a target of miR-595 and deficiency contributes to ribosomal dysgenesis Heba Alkhatabi O6 Next generation DNA sequencing panels for haemostatic and platelet disorders and for Fanconi anaemia in routine diagnostic service Anne Goodeve, Laura Crookes, Nikolas Niksic, Nicholas Beauchamp O7 Targeted sequencing panels and their utilization in personalized medicine Adel M. Abuzenadah O8 International biobanking in the era of precision medicine Jim Vaught O9 Biobank and biodata for clinical and forensic applications Bruce Budowle, Mourad Assidi, Abdelbaset Buhmeida O10 Tissue microarray technique: a powerful adjunct tool for molecular profiling of solid tumors Jaudah Al-Maghrabi O11 The CEGMR biobanking unit: achievements, challenges and future plans Abdelbaset Buhmeida, Mourad Assidi, Leena Merdad O12 Phylomedicine of tumors Sudhir Kumar, Sayaka Miura, Karen Gomez O13 Clinical implementation of pharmacogenomics for colorectal cancer treatment Angel Carracedo, Mahmood Rasool O14 From association to causality: translation of GWAS findings for genomic me

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LOW-FREQUENCY ELECTRONIC NOISE IN GRAPHENE TRANSISTORS: COMPARISON WITH CARBON NANOTUBES

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International Journal of High Speed Electronics and systems 2011年第1期20卷 161-170页

作者： GUANXIONG LIU WILLIAM STILLMAN SERGEY RUMYANTSEV MICHAEL SHUR ALEXANDER A. BALANDIN Nano-Device Laboratory Department of Electrical Engineering Materials Science and Engineering Program Bourns College of Engineering University of California – Riverside Riverside California 92521 USA Center for Integrated Electronics and Department of Electrical Computer and Systems Engineering Rensselaer Polytechnic Institute Troy New York 12180 USA Ioffe Physico-Technical Institute Russian Academy of Sciences St. Petersburg 194021 Russia Nano-Device Laboratory Department of Electrical Engineering and Materials Science Engineering Program Bourns College of Engineering University of California – Riverside Riverside California 92521 USA

We report results of the experimental investigation of the low-frequency noise in graphene transistors. The graphene devices were measured in three-terminal configuration. The measurements revealed low flicker noise levels with the normalized noise spectral density close to 1/f (f is the frequency) and the Hooge parameter α H ~10 -3 . Both top-gate and back-gate devices were studied. The analysis of the noise spectral-density dependence on the gate biases helped us to elucidate the noise sources in these devices. We compared the noise performance of graphene devices with that of carbon nanotube devices. It was determined that graphene devices works better than carbon nanotube devices in terms of the low-frequency noise. The obtained results are important for graphene electronic, communication and sensor applications.

关键词： graphene 1/ f noise carbon nanotubes low-frequency noise graphene transistors

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Complex-valued functional link network design by orthogonal least squares method for function approximation problems

Complex-valued functional link network design by orthogonal ...

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International Joint Conference on Neural Networks (IJCNN)

作者： Md. Faijul Amin Ramasamy Savitha Muhammad Ilias Amin Kazuyuki Murase Department of Systems Design Engineering Graduate School of Engineering University of Fukui Fukui Japan School of Electrical and Electronics Engineering Nanyang Technological University Singapore Department of Computer Science and Engineering United International University Dhaka Bangladesh Research and Education Program for Life Science University of Fukui Fukui Japan

This paper presents a fully complex-valued functional link network (CFLN). The CFLN is a single-layered neural network, which introduces nonlinearity in the input layer using nonlinear functions of the original input variables. In this study, we consider multivariate polynomials as the nonlinear functions. Unlike multilayer neural networks, the CFLN is free from local minima problem, and it offers very fast learning in parameters because of its linear structure. In the complex domain, polynomial based CFLN has an additional advantage of not requiring activation functions, which is a major concern in the complex-valued neural networks. However, it is important to select a smaller subset of polynomial terms (monomials) for faster and better performance, since the number of all possible monomials may be quite large. In this paper, we use the orthogonal least squares method in a constructive fashion (starting from lower degree to higher) for the selection of a parsimonious subset of monomials. Simulation results demonstrate that computing CFLN in purely complex domain is advantageous than in double-dimensional real domain, in terms of number of connection parameters, faster design, and possibly generalization performance. Moreover, our proposed CFLN compares favorably with several other multilayer networks in the complex domain.

关键词： Polynomials Nonhomogeneous media Educational institutions Algorithm design and analysis Function approximation Neural networks Input variables

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Hardware Particle Swarm Optimization with passive congregation for embedded applications

Hardware Particle Swarm Optimization with passive congregati...

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Southern Conference on programmable Logic

作者： Daniel M. Muñoz Carlos H. Llanos Leandro dos S. Coelho Mauricio Ayala-Rincón Department of Mechanical Engineering Automation and Control Group/GRACO University of Brasilia Brazil Industrial and Systems Engineering Graduate Program LAS/PPGPES Pontifical Catholic University of Paraná Curitiba Parana Brazil Department of Computer Science and Mathematics University of Brasilia Brazil

Achieving high performance optimization algorithms for embedded applications can be very challenging, particularly when several requirements such as high accuracy computations, short elapsed time, area cost, low power consumption and portability must be accomplished. This paper proposes a hardware implementation of the Particle Swarm Optimization algorithm with passive congregation (HPPSOpc), which was developed using several floating-point arithmetic libraries. The passive congregation is a biological behavior which allows the swarm to preserve its integrity, balancing between global and local search. The HPPSOpc architecture was implemented on a Virtex5 FPGA device and validated using two multimodal benchmark problems. Synthesis, simulation and execution time results demonstrates that the passive congregation approach is a low cost solution for solving embedded optimization problems with a high performance.

关键词： Hardware computer architecture Software Field programmable gate arrays Benchmark testing Optimization Software algorithms

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Evaluation of a Closed Loop Inductive Power Transmission System on an Awake Behaving Animal Subject

Evaluation of a Closed Loop Inductive Power Transmission Sys...

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Annual International Conference of the IEEE engineering in Medicine and Biology Society

作者： Mehdi Kiani Ki Yong Kwon Fei Zhang Karim Oweiss Maysam Ghovanloo GT-Bionics Lab School of Electrical and Computer Engineering at Georgia Institute of Technology Neural Systems Engineering Lab ECE Dept. College of Eng. at Michigan State University ECE Dept. and Neuroscience Program at Michigan State University

ISBN: (纸本)9781424441211

This paper presents in vivo experimental results for a closed loop wireless power transmission system to implantable devices on an awake behaving animal subject. In this system, wireless power transmission takes place across an inductive link, controlled by a commercial off-the-shelf (COTS) radio frequency identification (RFID) transceiver (TRF7960) operating at 13.56 MHz. Induced voltage on the implantable secondary coil is rectified, digitized by a 10-bit analog to digital converter, and transmitted back to the primary via back telemetry. Transmitter (Tx) and receiver (Rx) circuitry were mounted on the back of an adult rat with a nominal distance of ～7 mm between their coils. Our experiments showed that the closed loop system was able to maintain the Rx supply voltage at the designated 3.8 V despite changes in the coils' relative distance and alignment due to animal movements. The Tx power consumption changed between 410 ～ 560 mW in order to deliver 27 mW to the receiver. The open loop system, on the other hand, showed undesired changes in the Rx supply voltage while the Tx power consumption was constant at 660 mW.

关键词： Coils Inductive power transmission Closed loop systems awake Induction loop systems analog digital converter supply voltage Power consumption Implants and Prostheses Contraceptive Coil Radio frequency identification Back Open loop systems Digitizers

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Comparison of disturbance rejection performance between sliding-mode control and equivalent-input-disturbance approach

Comparison of disturbance rejection performance between slid...

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IEEE International Conference on Mechatronics

作者： She, Jinhua Pan, Yaodong Hashimoto, Hiroshi Wu, Min School of Computer Science Tokyo Univ. of Tech. Hachioji 192-0982 Japan Control Systems Eng Honeywell Canada Mississauga ON L5L3S6 Canada Master Program of Innovation for Design and Eng Advanced Institute of Industrial Tech. Tokyo 140-0011 Japan School of Information Science and Engineering Central South Univ. Changsha 410083 China

ISBN: (纸本)9781612849836

Sliding mode control (SMC) has been considered as a powerful method for disturbances rejection. On the other hand, we have presented an equivalent-input disturbance (EID) approach to reject disturbances. This paper takes a dual-stage feed drive as an example to compare these two methods. The example shows that, while the EID approach obtains almost the same disturbance rejection performance for matched disturbances as that of the SMC does, it can reject unmatched disturbances. This shows the superiority of the EID approach over SMC method. © 2011 IEEE.

关键词： Sliding mode control

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Opposition-based shuffled PSO with passive congregation applied to FM matching synthesis

Opposition-based shuffled PSO with passive congregation appl...

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Congress on Evolutionary Computation

作者： Daniel M. Muñoz Carlos H. Llanos Leandro dos S. Coelho Mauricio Ayala-Rincón Department of Mechanical Engineering Automation and Control Group/GRACO University of Brasilia Brasilia Brazil Industrial and Systems Engineering Graduate Program LAS/PPGEPS Pontifical Catholic University of Paraná Curitiba Parana Brazil Department of Computer Science and Mathematics University of Brasilia Brasilia Brazil

Synthesis of musical instruments or human voice is a time consuming process which requires theoretical and experimental knowledge about the synthesis engine. Commonly, performers need to deal with synthesizer interfaces and a process of trial and error for creating musical sounds similar to a target sound. This drawback can be overcome by adjusting automatically the synthesizer parameters using optimization algorithms. In this paper a hybrid particle swarm optimization (PSO) algorithm is proposed to solve the frequency modulation (FM) matching synthesis problem. The proposed algorithm takes advantage of a shuffle process for exchanging information between particles and applies the selective passive congregation and the opposition-based learning approaches to preserve swarm diversity. Both approaches for injecting diversity are based on simple operators, preserving the easy implementation philosophy of the particle swarm optimization. The proposed hybrid particle swarm optimization algorithm was validated for a three-nested FM synthesizer, which represents a 6-dimensional multimodal optimization problem with strong epistasis. Simulation results revealed that the proposed algorithm presented promising results in terms of quality of solutions.

关键词： Frequency modulation Optimization Equations Convergence Particle swarm optimization Genetic algorithms

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K, T and D-like fuzzy Kripke models

K, T and D-like fuzzy Kripke models

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Annual Meeting of The North American Fuzzy Information Processing Society

作者： Bedregal, Benjamin Santiago, Regivan H. N. Benevides, Mario Viana, Petrucio Group of Logic Language Information Theory and Applications - LoLITA Department of Informatics and Applied Mathematics Federal University of Rio Grande Do Norte 59072-970 Natal-RN Brazil Program of Engineering of Systems and Computing - PESC Department of Computer Science Federal University of Rio de Janeiro 21941-972 Rio de Janeiro-RJ Brazil Department of Analysis Fluminense Federal University 24020-140 Niterói-RJ Brazil

ISBN: (纸本)9781612849676

The idea of a Kripke semantics endowed with possibility/plausibility information is not new;in fact there are different approaches for that;see: [6], [13], [16], [19]. This paper follows the approach found in [6], but whereas [6] provides a fixed interpretation for connectives into [0,1] here we provide a characterization of a fuzzy semantics for connectives in such a way that the resulting fuzzy frames: K, T and D, are described precisely by the set of statements which also describes, respectively, the usual modal systems K, T and D. © 2011 IEEE.

关键词： Semantics

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Low-frequency 1/f noise in bismuth selenide Topological Insulators

Low-frequency 1/f noise in bismuth selenide Topological Insu...

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International Conference on Noise and Fluctuations (ICNF)

作者： M. Z. Hossain K. M. F. Shahil D. Teweldebrhan A. A. Balandin S. L. Rumyantsev M. Shur Nano-Device Laboratory Department of Electrical Engineering and Materials Science and Engineering Program University of California Riverside CA USA Department of Electrical Computer and Systems Engineering and Center for Integrated Electronics Rensselaer Polytechnic Institute New York USA Ioffe Institute The Russian Academy of Sciences St. Petersburg Russia

ISBN: (纸本)9781457701894

Topological insulators is a newly discovered class of materials with the Dirac cone type dispersion at the surface and conventional band in the volume of the material. We present results of the study of the low-frequency excess noise in thin films made of Bi 2 Se 3 topological insulator material. The films were prepared through mechanically cleavage from the bulk crystal via the “graphene-like” exfoliation procedure. We verified the quality and crystallinity of Bi 2 Se 3 samples with the micro-Raman spectroscopy. Our fabricated devices have linear current voltage characteristics in the low bias region with the current fluctuation noise spectral density SI proportional to 1/f for frequency f less than 10 kHz. The noise spectral density SI showed the square law dependence on the source-drain current and changed from about ~10 -22 to 10 -18 A 2 /Hz as current changes form ~10 -7 to 10 -5 A. Our results can be used for understanding electron transport and trap dynamics, and for reducing low-frequency noise in topological insulator devices.

关键词： Noise Insulators Films Crystals Temperature measurement Resistance

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A Propositional Dynamic Logic for concurrent programs based on the π-Calculus

A Propositional Dynamic Logic for concurrent programs based ...

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作者： Benevides, Mario R. F. Schechter, L. Menasché Computer Science Department and Systems and Computer Engineering Program Federal University of Rio de Janeiro Brazil Systems and Computer Engineering Program Federal University of Rio de Janeiro Brazil

This work presents a Propositional Dynamic Logic (πDL) in which the programs are described in a language based on the π-Calculus without replication. Our goal is to build a dynamic logic that is suitable for the description and verification of properties of communicating concurrent systems, in a similar way as PDL is used for the sequential case. We build a simple Kripke semantics for this logic, provide a complete axiomatization for it and show that it has the finite model property. © 2010 Elsevier B.V. All rights reserved.

关键词： Semantics

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