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A web-based, hospital-wide health care-associated bloodstream infection surveillance and classification system: Development and evaluation

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JMIR Medical Informatics 2015年第3期3卷 e31页

作者： Tseng, Yi-Ju Wu, Jung-Hsuan Lin, Hui-Chi Chen, Ming-Yuan Ping, Xiao-Ou Sun, Chun-Chuan Shang, Rung-Ji Sheng, Wang-Huei Chen, Yee-Chun Lai, Feipei Chang, Shan-Chwen Graduate Institute of Biomedical Electronics and Bioinformatics National Taiwan University Taipei Taiwan Computational Health Informatics Program Boston Children's Hospital Boston MA United States Department of Electrical Engineering National Taiwan University Taipei Taiwan Center for Infection Control National Taiwan University Hospital Taipei Taiwan National Taiwan University Hospital Information Systems Office Taipei Taiwan Department of Computer Science and Information Engineering National Taiwan University Taipei Taiwan Department of Internal Medicine National Taiwan University Hospital and College of Medicine Taipei Taiwan National Health Research Institutes National Institute of Infectious Diseases and Vaccinology Miaoli Taiwan

Background: Surveillance of health care-associated infections is an essential component of infection prevention programs, but conventional systems are labor intensive and performance dependent. Objective: To develop an automatic surveillance and classification system for health care-associated bloodstream infection (HABSI), and to evaluate its performance by comparing it with a conventional infection control personnel (ICP)-based surveillance system. Methods: We developed a Web-based system that was integrated into the medical information system of a 2200-bed teaching hospital in Taiwan. The system automatically detects and classifies HABSIs. Results: In this study, the number of computer-detected HABSIs correlated closely with the number of HABSIs detected by ICP by department (n=20;r=.999 P<.001) and by time (n=14;r=.941;P<.001). Compared with reference standards, this system performed excellently with regard to sensitivity (98.16%), specificity (99.96%), positive predictive value (95.81%), and negative predictive value (99.98%). The system enabled decreasing the delay in confirmation of HABSI cases, on average, by 29 days. Conclusions: This system provides reliable and objective HABSI data for quality indicators, improving the delay caused by a conventional surveillance system. © 2020 JMIR Publications Inc. All rights reserved.

关键词： Health care-associated infection Infection control Information systems Surveillance Web-based services

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Predictable and precise template-free CRISPR editing of pathogenic variants (vol 563, pg 646, 2018)

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NATURE 2019年第7746期567卷 E1-E2页

作者： Shen, Max W. Arbab, Mandana Hsu, Jonathan Y. Worstell, Daniel Culbertson, Sannie J. Krabbe, Olga Cassa, Christopher A. Liu, David R. Gifford, David K. Sherwood, Richard I. Computational and Systems Biology Program Massachusetts Institute of Technology Cambridge USA Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology Cambridge USA Merkin Institute of Transformative Technologies in Healthcare Broad Institute of Harvard and MIT Cambridge USA Department of Chemistry and Chemical Biology Harvard University Cambridge USA Howard Hughes Medical Institute Harvard University Cambridge USA Department of Biological Engineering Massachusetts Institute of Technology Cambridge USA Molecular Pathology Unit Center for Cancer Research and Center for Computational and Integrative Biology Massachusetts General Hospital Charlestown USA Division of Genetics Department of Medicine Brigham and Women’s Hospital and Harvard Medical School Boston USA Hubrecht Institute for Developmental Biology and Stem Cell Research Royal Netherlands Academy of Arts and Sciences (KNAW) Utrecht The Netherlands Broad Institute of MIT and Harvard Cambridge USA Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge USA

In this Article, a data processing error affected Fig. 3e and Extended Data Table 2; these errors have been corrected online.

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Diffusive topological transport in spatiotemporal thermal lattices

arXiv

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arXiv 2021年

作者： Xu, Guoqiang Yang, Yihao Zhou, Xue Chen, Hongsheng Alù, Andrea Qiu, Cheng-Wei Department of Electrical and Computer Engineering National University of Singapore Kent Ridge117583 Singapore Interdisciplinary Center for Quantum Information State Key Laboratory of Modern Optical Instrumentation ZJU-Hangzhou Global Scientific and Technological Innovation Center Zhejiang University Hangzhou China School of Computer Science and Information Engineering Chongqing Technology and Business University Chongqing400067 China ZJU-Hangzhou Global Science and Technology Innovation Center Key Lab. of Advanced Micro/Nano Electronic Devices & Smart Systems of Zhejiang Zhejiang University Hangzhou310027 China International Joint Innovation Center ZJU-UIUC Institute The Electromagnetics Academy at Zhejiang University Zhejiang University Haining314400 China Photonics Initiative Advanced Science Research Center City University of New York New YorkNY10031 United States Physics Program Graduate Center of the City University of New York New YorkNY10016 United States

Topological insulating phases are usually found in periodic lattices stemming from collective resonant effects, and it may thus be expected that similar features may be prohibited in thermal diffusion, given its purely dissipative and largely incoherent nature. We report the diffusion-based topological states supported by spatiotemporally-modulated advections stacked over a fluidic surface, thereby imitating a periodic propagating potential in effective thermal lattices. We observe edge and bulk states within purely nontrivial and trivial lattices, respectively. At interfaces between these two types of lattices, the diffusive system exhibits interface states, manifesting inhomogeneous thermal properties on the fluidic surface. Our findings establish a framework for topological diffusion and thermal edge/bulk states, and it may empower a distinct mechanism for flexible manipulation of robust heat and mass transfer. © 2021, CC BY.

关键词： Interface states

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A Radial Basis Function Spike Model for Indirect Learning via Integrate-and-Fire Sampling and Reconstruction Techniques

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Advances in Artificial Neural systems 2012年第1期2012卷

作者： X. Zhang G. Foderaro C. Henriquez A. M. J. VanDongen S. Ferrari Laboratory for Intelligent Systems and Control (LISC) Department of Mechanical Engineering and Materials Science Duke University Durham NC 27708 USAduke.edu Department of Biomedical Engineering and Department of Computer Science Duke University Durham NC 27708 USAduke.edu Program in Neuroscience & Behavioral Disorders Duke-NUS Graduate Medical School Singapore Singapore

This paper presents a deterministic and adaptive spike model derived from radial basis functions and a leaky integrate-and-fire sampler developed for training spiking neural networks without direct weight manipulation. Several algorithms have been proposed for training spiking neural networks through biologically-plausible learning mechanisms, such as spike-timing-dependent synaptic plasticity and Hebbian plasticity. These algorithms typically rely on the ability to update the synaptic strengths, or weights, directly, through a weight update rule in which the weight increment can be decided and implemented based on the training equations. However, in several potential applications of adaptive spiking neural networks, including neuroprosthetic devices and CMOS/memristor nanoscale neuromorphic chips, the weights cannot be manipulated directly and, instead, tend to change over time by virtue of the pre- and postsynaptic neural activity. This paper presents an indirect learning method that induces changes in the synaptic weights by modulating spike-timing-dependent plasticity by means of controlled input spike trains. In place of the weights, the algorithm manipulates the input spike trains used to stimulate the input neurons by determining a sequence of spike timings that minimize a desired objective function and, indirectly, induce the desired synaptic plasticity in the network.

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Windows computer laboratory as a tutorial for undergraduate electromagnetics

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computer Applications in engineering Education 1995年第3期3卷 183-183页

作者： McCulloch, J. Keddy, W.A. Stuchly, M.A. University of Victoria Department of Electrical and Computer Engineering University of Victoria Victoria British Columbia Canada Janet McCulloch:is a native of Toronto Canada where she briefly attended both York University and the University of Toronto before she set off on a year-long adventure through the Middle East and North Africa. When she returned to Canada she relocated to California. She spent a number of years living both in Los Angeles and coastal Northern California interspersed with several extended trips through the United States Mexico and Central America. Ms. McCulloch moved to Victoria British Columbia in 1989 and a year later registered in the cooperative education program in Electrical Engineering at the University of Victoria. She is presently in the fifth and final year of the program and has her sights set on graduate school. Besides the work described in this article she has been very much involved in the use of technology to assist in the delivery of curriculum at the senior secondary level. She lives on a country property a half-hour from the University with her husband her horse and three cats. W. Alfred Keddy:is an applications programmer/analyst for the Department of Electrical and Computer Engineering at the University of Victoria. He received a BEng (1988) in Electrical Engineering and an MASc (1994) from the University of Victoria. His research interests include distributed systems image processing local area networks VLSI and DSP system design for computation and communication and human–computer interface design. Maria A. Stuchly:received an MSc in Electrical Engineering in 1962 from Warsaw Technical University and a PhD in Electrical Engineering from the Polish Academy of Sciences in 1970. Between the years of 1962 and 1970 she was with the Warsaw Technical University an Institute of the Polish Academy of Sciences. After immigrating to Canada during 1970 her first position was with the University of Manitoba. In 1976 she became employed by the Bureau of Radi

Contents and implementation of a computer laboratory for undergraduate electromagnetics are described. The laboratory consists of four 3-hour sessions covering vector calculus, Maxwell's equations (integral and differential forms), wave propagation in materials, and wave behavior at planar interfaces. Each session contains theory (in the Help file), animations (where relevant) and a quiz. The program runs on IBM compatible 486-based PCs in a Windows environment and uses the Borland C ++ 4.0 compiler.

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Influence of human engineering on manning levels and human performance on ships

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NAVAL ENGINEERS JOURNAL 1997年第5期109卷 67-76页

作者： Anderson, DE Oberman, FR Malone, TB Baker, CC David E. Anderson:has a bachelor of science degree in environmental engineering from Florida Technological University and a master's degree in environmental engineering from the University of Central Florida. He is a graduate of the Naval Sea Systems Command's Engineer-In-Training (EIT) Program. Mr. Anderson was instrumental in introducing the collective protection system (CPS) in the U.S. Navy developing the initial forward-fit package for the USS Gunston Hall and the engineering change proposal (ECP) for the USS Wasp. In 1990 he joined the Human Systems Integration (HSI) Division (SEA 55W5) where he was task leader for auxiliary ships. He is currently the HSI manager for the future technology variant of the SeaLift ship and the future carrier. Association of Scientists and Engineers 33rdAnnual Technical Symposium 26 April 1996. Fred R. Oberman:has B.A. and M.A. degrees from the University of Chicago and Loyola University (experimental psychology) and an M.S. degree in industrial engineering and operations research from Virginia Polytechnic Institute (VPI). He has more than 30 years experience in HSI management planning research analysis design and testing in government and private sector positions. He is currently responsible for NavSea HSI generic research and tool development efforts. He is responsible for Human Engineering Specifications and Standards (Commercial Hypertext) and is the NavSea 03D7 representative on HSI in Performance Specifications and for integration of HSI within Integrated Logistic Support (ILS). He has served as DoD HSI SubTAG chair and member of the Simulation and Modeling Test and Evaluation Display and Control Systems Human Computer Interaction Specifications and Standards and Systems Design Sub Tags as a member of the Society of Naval Architects and Marine Engineers (SNAME) Systems Safety Panel and a member of NATO RSG 14 on man-machine analysis. Thomas B. Malone: CHFEP received a Ph.D. in experimental psychology from Fordham University in 1964. He is president of Carlow

The objectives of Human engineering (HE) are generally viewed as increasing human performance, reducing human error, enhancing personnel and equipment safety, and reducing training and related personnel costs. There are other benefits that are thoroughly consistent with the direction of the Navy of the future, chief among these is reduction of required numbers of personnel to operate and maintain Navy ships. The Naval Research Advisory Committee (NRAC) report on Man-Machine Technology in the Navy estimated that one of the benefits from increased application of man-machine technology to Navy ship design is personnel reduction as well as improving system availability, effectiveness, and safety The objective of this paper is to discuss aspects of the human engineering design of ships and systems that affect manning requirements, and impact human-performance and safety The paper will also discuss how the application of human engineering leads to improved performance, and crew safety, and reduced workload, all of which influence manning levels. Finally, the paper presents a discussion of tools and case studies of good human engineering design practices which reduce manning.

关键词： Human engineering

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Constrained Deep One-Class Feature Learning For Classifying Imbalanced Medical Images

arXiv

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arXiv 2021年

作者： Gao, Long Liu, Chang Arefan, Dooman Panigrahy, Ashok Wu, Shandong Department of Radiology School of Medicine University of Pittsburgh 4200 Fifth Ave PittsburghPA15260 United States College of Computer National University of Defense Technology Changsha410073 China Department of Bioengineering Swanson School of Engineering University of Pittsburgh 4200 Fifth Ave PittsburghPA15260 United States Department of Radiology University of Pittsburgh Medical Center Children’s Hospital of Pittsburgh 4401 Penn Ave PittsburghPA15224 United States Department of Biomedical Informatics University of Pittsburgh 4200 Fifth Ave Pittsburgh15260 United States Intelligent Systems Program University of Pittsburgh 4200 Fifth Ave PittsburghPA15260 United States

Medical image data are usually imbalanced across different classes. One-class classification has attracted increasing attention to address the data imbalance problem by distinguishing the samples of the minority class from the majority class. Previous methods generally aim to either learn a new feature space to map training samples together or to fit training samples by autoencoder-like models. These methods mainly focus on capturing either compact or descriptive features, where the information of the samples of a given one class is not sufficiently utilized. In this paper, we propose a novel deep learning-based method to learn compact features by adding constraints on the bottleneck features, and to preserve descriptive features by training an autoencoder at the same time. Through jointly optimizing the constraining loss and the autoencoder’s reconstruction loss, our method can learn more relevant features associated with the given class, making the majority and minority samples more distinguishable. Experimental results on three clinical datasets (including the MRI breast images, FFDM breast images and chest X-ray images) obtain state-of-art performance compared to previous methods. © 2021, CC BY.

关键词： Medical imaging

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Navy's chlorofluorocarbon/Halon program

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Naval Engineers Journal 1991年第3期103卷 107-117页

作者： Krinsky, Joel L. Noel, William Joel L. Krinskyholds a B.S. degree from the U.S. Merchant Marine Academy (1960) and an M.B.A. from the American University (1966). He is currently the director of The HVAC Submarine Life Support Division within NavSea. He formerly served as the deputy director of the Auxiliaries Division and head of the Air Compressor/Forced Draft Blowers and Valves and Piping Branches within the Auxiliaries Division. He has thirty years experience in the marine engineering and computer fields. He sailed for two years in the merchant marine and then began his career in the Bureau of Ships in 1962 as a project engineer in the Boiler and Heat Exchanger Branch. Mr. Krinsky then served as the systems acquisition manager for navigation systems on attack submarines and aircraft carriers. Mr. Krinsky entered private industry with IBM in 1967 spent eight years in the computer industry serving in various capacities and returned to NavSea in 1975. He served in the U.S. Navy Reserve from 1961 to 1967 and is a member of ASE ASNE and ASTM. Mr. Krinsky currently chairs the ASTM subcommittee for shipboard HVAC (F25.11.07) and is writing the heating ventilation air conditioning and refrigeration chapter of the revised SNAME text on Marine Engineering. William Noelgraduated from Drexel University in 1984 with a B.S. degree in mechanical engineering. He worked at the Naval Ship Systems Engineering Station in Philadelphia in the Air Compressor Branch where he directed improvements to compressed air ship silencing systems. In 1985 he was hired at the Naval Sea Systems Command and spent two years working in the Auxiliary Machinery Division where he was life cycle manager for various air compressors and compressed air system components. In 1989 he earned an M.S. degree in mechanical engineering from the University of Maryland specializing in multi-phase fluid flow and heat transfer phenomena. Since 1987 Mr. Noel has been the project engineer charged with developing replacement refrigerants and fire fighting agents in executing the Navy CFC/

The Naval Sea systems Command is executing a three-phase program to ensure compliance with national regulations, DoD policy, and Navy instructions mandating the phase-out of CFC and Halon use by the Navy. The Navy uses significant quantities of CFCs and Halon as solvents, refrigerants, and fire-fighting agents both in military operations and through specifications and contracts for weapons and support equipment. Phase one of the program plan will be to conserve chemicals through reclaiming and recycling, and by establishing and maintaining a chemical inventory of CFCs and Halons. Phase two will research, develop, and test substitute chemicals and alternative technologies for existing CFC uses. This research will be pursued through Navy and government laboratories, cooperation with chemical and equipment manufacturers, and by participation in government/industry consortiums. Finally, phase three will deploy the replacement chemicals and new technologies into the fleet, and institutionalize the conservation measures developed in phase one. This paper discusses in detail the three phases of the Navy program, and relates the Navy effort to DoD policy, the Montreal Protocol, and Congressional legislation. Unique Navy concerns, research initiatives, and vintaging scenarios for existing equipment are presented.

关键词： Freons

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Retraction: Sylabus and Matrials Design for Vocational Student and Its Dissemination Using Website (J. Phys.: Conf. Ser. 1114 012023)

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Journal of Physics: Conference Series 2018年第1期1114卷

作者： Astro Julida Harahap Erianto Ongko Hotler Manurung Dian Kurnia H Hartono Dahlan Abdullah Cut Ita Erliana Hardianto Djanggih Kundharu Saddhono Dian Rianita Muhammad Ikhsan Setiawan Yuliyanto Budi Setiawan Rosida Tiurma Manurung S Sriadhi Mangasi Sinurat Aisyah Siregar Rapat Piter Soni Hutauruk Nico Benjamain Sibarani 1 Department of Informatics Akademi Teknologi Industri Immanuel Medan Indonesia Department of Computer Systems Universitas Pancabudi Medan Indonesia Department of Computer Science STMIK IBBI Medan Indonesia Department of Informatics Universitas Malikussaleh Aceh Indonesia Department of Industrial Engineering Universitas Malikussaleh Aceh Indonesia Graduate Program Universitas Sebelas Maret Surakarta Indonesia Department of Administration University of Lancang Kuning Pekanbaru Indonesia Department of Civil Engineering Narotama University Surabaya Indonesia Study Program of Communication Studies Universitas Semarang Indonesia Graduate Program in Scientific Psychology Universitas Kristen Maranatha Indonesia Department of Electrical Engineering Universitas Negeri Medan Indonesia STIE Bina Karya Tebing Tinggi Indonesia

This paper was retracted by IOP Publishing on 12 December 2018. This paper was published due to a technical error and was not intended to be included in this journal. Retraction published: 8 February 2019

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Modelling combat system manning and manpower reduction

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NAVAL ENGINEERS JOURNAL 1999年第3期111卷 153-171页

作者： Roos, CH Carl H. Roos:is a Senior Engineer with Logicon-Syscon. A graduate of the University of Pittsburgh with a BSEE degree he has over 35 years experience in functional operational combat system fire control interface and computer program design. As technology changed and the combat system was upgraded Mr. Roos maintained his level of technical expertise by taking graduate-level courses in computer science modelling & structured analysis networking & fiber optics. He has worked in various capacities on the LHD LHA DDG 993 DD 963 LPD 17 LCC LPD 13 CGN 38 CGN 9 CG 26 and the DDG Class Combat Systems. In recent years Mr. Roos has been responsible for managing directing and performing engineering design and analysis efforts associated with Battle Management Organization (BMO) functional analysis and operational analysis. These efforts were used in defining combat system operational requirements shipboard space requirements and integration requirements. His paper “Configuration Management of Digital Programs” was published at the 1972 IEEE Southeastern Conrence.

NAVSEA 03K41 is responsible for generating Combat System Rattle Management Organizations (BMO) and Functional Flow Diagrams (FFD). Several years ago, NAVSEA provided the resources to conduct a functional analysis that would support the development and validation of the BMOs and FFDs. The major obstacle in performing the analysis was obtaining a consensus on how the functional hierarchy was to be structured. The non-optimum organization of the hierarchy was selected;as a result, the functions were difficult to define, find, use, and validate. Recognizing the shortcomings of this effort, research was conducted to evaluate state-of-the-art structured modelling techniques, concepts, and methodologies. Two modelling concepts by James Martin were found to be applicable for the combat system functional analysis: Enterprise Modelling Concept and Functional Decomposition Modelling Concept. The Structure Modelling definitions of Whitten, Bently, and Barlow provided the guidelines for using the Martin concepts. During the ensuing BMO and FFD development efforts, a Ship's Combat System (SCS) Modelling concept evolved and a SCS Model was developed. This paper addresses how the modelling concepts and tools are used in the BMO and FFD development and validation process. Data from the SCS Model provides the basis for defining combat system requirements (e.g., software, data display, database, networking, etc.).

关键词： Naval vessels

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