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Automating Care by Self-maintainability for Full Laboratory Automation

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arXiv 2025年

作者： Ochiai, Koji Tahara-Arai, Yuya Kato, Akari Kaizu, Kazunari Kariyazaki, Hirokazu Umeno, Makoto Takahashi, Koichi Kanda, Genki N. Ozaki, Haruka Laboratory for Biologically Inspired Computing RIKEN Center for Biosystems Dynamics Research 6-7-1 Minatojima Minamimachi Chuo-ku Hyogo Kobe650-0047 Japan Bioinformatics Laboratory Institute of Medicine University of Tsukuba 1-1-1 Tennodai Ibaraki Tsukuba305-8577 Japan Ph.D. Program in Humanics School of Integrative and Global Majors University of Tsukuba 1-1-1 Tennodai Ibaraki Tsukuba305-8577 Japan Laboratory Automation Suppliers’ Association 2-1-8 Minatojima Minamimachi Chuo-ku Hyogo Kobe650-0047 Japan Cell Modeling and Simulation Group Exploratory Research Center on Life and Living Systems National Institutes of Natural Sciences 5-1 Higashiyama Myodaiji Aichi Okazaki444-8787 Japan Robotics Division YASKAWA Electric Corporation 2-1 Kurosaki Shiroishi Yahatanishi-ku Kitakyushu Fukuoka806-0004 Japan BAIKEIDO LLC 3-8-1 Asano Kokurakita-ku Kitakyushu Fukuoka802-0001 Japan Graduate School of Media and Governance Keio University 5322 Endo Fujisawa-shi Kanagawa252-0882 Japan Medical Research Laboratory Institute of Integrated Research Institute of Science Tokyo 1-5-45 Yushima Bunkyo-ku Tokyo113-8519 Japan Center for Artificial Intelligence Research University of Tsukuba 1-1-1 Tennodai Ibaraki Tsukuba305-8577 Japan

The automation of experiments in life sciences and chemistry has significantly advanced with the development of various instruments and AI technologies. However, achieving full laboratory automation, where experiments conceived by scientists are seamlessly executed in automated laboratories, remains a challenge. We identify the lack of automation in planning and operational tasks—critical human-managed processes collectively termed "care"—as a major barrier. Automating care is the key enabler for full laboratory automation. To address this, we propose the concept of self-maintainability (SeM): the ability of a laboratory system to autonomously adapt to internal and external disturbances, maintaining operational readiness akin to living cells. A SeM-enabled laboratory features autonomous recognition of its state, dynamic resource and information management, and adaptive responses to unexpected conditions. This shifts the planning and execution of experimental workflows, including scheduling and reagent allocation, from humans to the system. We present a conceptual framework for implementing SeM-enabled laboratories, comprising three modules—Requirement manager, Labware manager, and Device manager—and a Central manager. SeM not only enables scientists to execute envisioned experiments seamlessly but also provides developers with a design concept that drives the technological innovations needed for full automation. Copyright © 2025, The Authors. All rights reserved.

关键词： Information management

Image Size, Color Depth, Age variant on Convolution Neural Network 1

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Image Size, Color Depth, Age variant on Convolution Neural N...

1st Indonesian Association for Pattern Recognition International Conference, INAPR 2018

作者： Pranoto, Hady Budiharto, Widodo Hendric Spits Warnars, Harco Leslie Matsuo, Tokuro Heryadi, Yaya Computer Science Department School of Computer Science Bina Nusantara University Jakarta11480 Indonesia Computer Science Department BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta11480 Indonesia Graduate School of Industrial Technology Advanced Institute of Industrial Technology Tokyo Japan

ISBN: (纸本)9781538694220

Facial recognition as of biometric authentication used in the field of security, military, finance and daily use is become a trend or famous, because of its natural and not intrusive nature. Many methods for face recognition such as holistic learning, the use of local features, shallow learning and deep learning, some methods are susceptible to variations in pose change, illumination, expression and age variation. State of the art of face recognition today is a deep learning technique that delivers high accuracy. In this paper author replicate an face recognition using deep learning architecture called OpenFace Convolutional Neural Network. In this research author make variation on the size of image, color dept and age, and see how that factor impact on accuracy of face recognition in that architecture. As the result from the research, the accuracy of a model depends on the image size, color depth, and age variation, but in OpenFace CNN that recognition still provides fairly good accuracy when reducing the size of image and color depth, as long as the image can still be detected on the landmark facial, so the alignment process can be done on the face image. © 2018 IEEE.

关键词： Face recognition

Long Short-Term Memory for Human Fall Detection Based Gamification on Unconstraint Smartphone Position

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Long Short-Term Memory for Human Fall Detection Based Gamifi...

International Congress on Applied Information Technology

作者： Maria Seraphina Astriani Yaya Heryadi Gede Putra Kusuma Edi Abdurachman Faculty of Computing and Media Bina Nusantara University Jakarta Indonesia Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Binus Graduate Program Bina Nusantara University Jakarta Indonesia

ISBN: (数字)9781728158624

ISBN: (纸本)9781728158631

Fall incident can caused health problem in elderly and people with special treatments. Fall detection method is needed to minimized the problem when human fallen and smartphone can be used as the device to detect it. Usually people carry smartphone in any positions and can make fall detection method difficult to detect when fall occurs. Long Short-Term Memory (LSTM) combined with Sigmoid helps to answer the challenge to handle smartphone accelerometer and gyroscope data in many smartphone orientation position. LSTM method on this experiment can achieved 91.67% for the accuracy result. Since the fall data occurs rarely and there may be insufficient data available, the gamification prospect implemented in fall detection application especially on “Bug” bounty can help researcher to enhance the accuracy result to make a better human fall detection method.

关键词： Sensors Accelerometers Gyroscopes Senior citizens computer bugs Androids Humanoid robots

Quantum-inspired classical sublinear-time algorithm for solving low-rank semidefinite programming via sampling approaches

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arXiv 2019年

作者： Chia, Nai-Hui Li, Tongyang Lin, Han-Hsuan Wang, Chunhao Department of Computer Science University of Texas Austin United States Department of Computer Science Institute for Advanced Computer Studies Joint Center for Quantum Information and Computer Science University of Maryland U.S. Department of Energy Office of Science Office of Advanced Scientific Computing Research Quantum Algorithms Teams program

Semidefinite programming (SDP) is a central topic in mathematical optimization with extensive studies on its efficient solvers. Recently, quantum algorithms with superpolynomial speedups for solving SDPs have been proposed assuming access to its constraint matrices in quantum superposition. Mutually inspired by both classical and quantum SDP solvers, in this paper we present a sublinear classical algorithm for solving low-rank SDPs which is asymptotically as good as existing quantum algorithms. Specifically, given an SDP with m constraint matrices, each of dimension n and rank poly(log n), our algorithm gives a succinct description and any entry of the solution matrix in time O(m · poly(log n, 1/Ε)) given access to a sample-based low-overhead data structure of the constraint matrices, where Ε is the precision of the solution. In addition, we apply our algorithm to a quantum state learning task as an application. Technically, our approach aligns with both the SDP solvers based on the matrix multiplicative weight (MMW) framework and the recent studies of quantum-inspired machine learning algorithms. The cost of solving SDPs by MMW mainly comes from the exponentiation of Hermitian matrices, and we propose two new technical ingredients (compared to previous sample-based algorithms) for this task that may be of independent interest: • Weighted sampling: assuming sampling access to each individual constraint matrix A1,..., Aτ, we propose a procedure that gives a good approximation of A = A1 + ··· + Aτ. • Symmetric approximation: we propose a sampling procedure that gives low-rank spectral decomposition of a Hermitian matrix A. This improves upon previous sampling procedures that only give low-rank singular value decompositions, losing the signs of eigenvalues. Copyright © 2019, The Authors. All rights reserved.

关键词： Singular value decomposition

A learning strategy for contrast-agnostic MRI segmentation

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arXiv 2020年

作者： Billot, Benjamin Greve, Douglas N. van Leemput, Koen Fischl, Bruce Iglesias, Juan Eugenio Dalca, Adrian V. Center for Medical Image Computing University College London United Kingdom Martinos Center for Biomedical Imaging Massachusetts General Hospital Harvard Medical School United States Department of Health Technology Technical University of Denmark Denmark Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology United States Program in Health Sciences and Technology Massachusetts Institute of Technology United States

We present a deep learning strategy that enables, for the first time, contrast-agnostic semantic segmentation of completely unpreprocessed brain MRI scans, without requiring additional training or fine-tuning for new modalities. Classical Bayesian methods address this segmentation problem with unsupervised intensity models, but require significant computational resources. In contrast, learning-based methods can be fast at test time, but are sensitive to the data available at training. Our proposed learning method, SynthSeg, leverages a set of training segmentations (no intensity images required) to generate synthetic scans of widely varying contrasts on the fly during training. These scans are produced using the generative model of the classical Bayesian segmentation framework, with randomly sampled parameters for appearance, deformation, noise, and bias field. Because each mini-batch has a different synthetic contrast, the final network is not biased towards any MRI contrast. We comprehensively evaluate our approach on four datasets comprising over 1,000 subjects and four MR contrasts. The results show that our approach successfully segments every contrast in the data, performing slightly better than classical Bayesian segmentation, and three orders of magnitude faster. Moreover, even within the same type of MRI contrast, our strategy generalizes significantly better across datasets, compared to training using real images. Finally, we find that synthesizing a broad range of contrasts, even if unrealistic, increases the generalization of the neural network. Our code and model are open source at https://***/BBillot/SynthSeg. Copyright © 2020, The Authors. All rights reserved.

关键词： Magnetic resonance imaging

Quantum computing hardware for HEP algorithms and sensing

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arXiv 2022年

作者： Alam, M. Sohaib Belomestnykh, Sergey Bornman, Nicholas Cancelo, Gustavo Chao, Yu-Chiu Checchin, Mattia Dinh, Vinh San Grassellino, Anna Gustafson, Erik J. Harnik, Roni McRae, Corey Rae Harrington Huang, Ziwen Kapoor, Keshav Kim, Taeyoon Kowalkowski, James B. Kramer, Matthew J. Krasnikova, Yulia Kumar, Prem Kurkcuoglu, Doga Murat Lamm, Henry Lyon, Adam L. Milathianaki, Despina Murthy, Akshay Mutus, Josh Nekrashevich, Ivan Oh, JinSu Özgüler, A. Barış Perdue, Gabriel Nathan Reagor, Matthew Romanenko, Alexander Sauls, James A. Stefanazzi, Leandro Tubman, Norm M. Venturelli, Davide Wang, Changqing You, Xinyuan van Zanten, David M.T. Zhou, Lin Zhu, Shaojiang Zorzetti, Silvia NASA Ames Research Center Moffett FieldCA94035 United States Mountain ViewCA94043 United States Fermi National Accelerator Laboratory BataviaIL60510 United States Scientific Computing Division Fermi National Accelerator Laboratory BataviaIL60510 United States Northwestern-Fermilab Center for Applied Physics and Superconducting Technologies Northwestern University EvanstonIL60208 United States Graduate Program in Applied Physics Northwestern University EvanstonIL60208 United States Theory Division Fermi National Accelerator Laboratory BataviaIL60510 United States Department of Physics Department of Electrical Computer and Energy Engineering University of Colorado Boulder CO80305 United States National Institute of Standards and Technology Boulder CO80305 United States Department of Physics and Astronomy Northwestern University EvanstonIL60208 United States Ames Laboratory U.S. Department of Energy AmesIA50011 United States Center for Photonic Communication and Computing ECE Department Northwestern University EvanstonIL60208 United States Rigetti Computing Inc. BerkeleyCA94710 United States NASA Ames Research Center Moffett FieldCA94035 United States

Quantum information science harnesses the principles of quantum mechanics to realize computational algorithms with complexities vastly intractable by current computer platforms. Typical applications range from quantum chemistry to optimization problems and also include simulations for high energy physics. The recent maturing of quantum hardware has triggered preliminary explorations by several institutions (including Fermilab) of quantum hardware capable of demonstrating quantum advantage in multiple domains, from quantum computing to communications, to sensing. The Superconducting Quantum Materials and Systems (SQMS) Center, led by Fermilab, is dedicated to providing breakthroughs in quantum computing and sensing, mediating quantum engineering and HEP based material science. The main goal of the Center is to deploy quantum systems with superior performance tailored to the algorithms used in high energy physics. In this Snowmass paper, we discuss the two most promising superconducting quantum architectures for HEP algorithms, i.e. three-level systems (qutrits) supported by transmon devices coupled to planar devices and multi-level systems (qudits with arbitrary N energy levels) supported by superconducting 3D cavities. For each architecture, we demonstrate exemplary HEP algorithms and identify the current challenges, ongoing work and future opportunities. Furthermore, we discuss the prospects and complexities of interconnecting the different architectures and individual computational nodes. Finally, we review several different strategies of error protection and correction and discuss their potential to improve the performance of the two architectures. This whitepaper seeks to reach out to the HEP community and drive progress in both HEP research and QIS hardware. Copyright © 2022, The Authors. All rights reserved.

关键词： High energy physics

Expression of concern: Microchip-based structure determination of low-molecular weight proteins using cryo-electron microscopy

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Nanoscale 2024年第9期16卷 4919页

作者： Michael A Casasanta G M Jonaid Liam Kaylor William Y Luqiu Maria J Solares Mariah L Schroen William J Dearnaley Jarad Wilson Madeline J Dukes Deborah F Kelly Department of Biomedical Engineering Pennsylvania State University University Park PA 16802 USA. Debkelly@psu.edu. Materials Research Institute Pennsylvania State University University Park PA 16802 USA. Bioinformatics and Genomics Graduate Program Huck Institutes of the Life Sciences Pennsylvania State University University Park PA 16802 USA. Molecular Cellular and Integrative Biosciences Graduate Program Huck Institutes of the Life Sciences Pennsylvania State University University Park PA 16802 USA. Department of Electrical and Computer Engineering Duke University Durham NC 27708 USA. RayBiotech Life Peachtree Corners GA 30092 USA. Applications Science Protochips Inc. Morrisville NC 27560 USA.

Expression of concern for 'Microchip-based structure determination of low-molecular weight proteins using cryo-electron microscopy' by Michael A. Casasanta , , 2021, , 7285-7293, https://***/10.1039/D1NR00388G.

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Corrections to "iPhantom: A Framework for Automated Creation of Individualized Computational Phantoms and its Application to CT Organ Dosimetry"

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IEEE journal of biomedical and health informatics 2022年第1期26卷 478页

作者： Wanyi Fu Shobhit Sharma Ehsan Abadi Alexandros-Stavros Iliopoulos Qi Wang Joseph Y Lo Xiaobai Sun William P Segars Ehsan Samei Department of Electrical and Computer Engineering and Carl E. Ravin Advanced Imaging Laboratories Duke University Durham NC USA Department of Physics and Carl E. Ravin Advanced Imaging Laboratories Duke University Durham NC USA Department of Computer Science Duke University Durham NC USA Computer Science and Artificial Intelligence Laboratory Massachusetts Institute of Technology Cambridge MA USA Department of Radiology the Fourth Clinical Hospital of Hebei Medical University Heibei China Departments of Electrical and Computer Engineering Biomedical Engineering Medical Physics Graduate Program and Carl E. Ravin Advanced Imaging Laboratories Duke University Durham NC USA Medical Physics Graduate Program and Radiology and the Carl E. Ravin Advanced Imaging Laboratories Departments of Biomedical Engineering Duke University Durham NC USA Carl E. Ravin Advanced Imaging Laboratories Medical Physics Graduate Program Department of Radiology Electrical and Computer Engineering Biomedical Engineering and Physics Duke University Durham NC USA

In [1], the dose estimation accuracy using the alternative baseline method under modulated tube current was not correctly calculated due to an unintentional simulation error.

关键词： Phantoms Image segmentation Computed tomography Image registration

Intelligent E-commerce for Special Needs

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Intelligent E-commerce for Special Needs

International Conference on Cyber and IT Service Management (CITSM)

作者： Diana Teresia Spits Warnars Leonardo Primadala Putra Logiansa Harco Leslie Hendric Spits Warnars Wiranto Herry Utomo School of Information Systems Bina Nusantara University Jakarta Indonesia BINUS Graduate Program - Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Computing President University Bekasi Indonesia

Special need is a person who need assistance for their disabilities which include medical, physical, mental or psychological such as person with autism, down syndrome, dyslexia, Attention Deficit Hyperactivity Disorder (ADHD), multiple sclerosis, schizophrenia, cystic fibrosis, cerebral palsy, muscular dystrophy, blindness, deafness, epilepsy, chronic asthma and so on. In this proposed research idea about intelligent E-commerce for special needs, we limited to four types of difficulties such as hearing difficulty, vision difficulty, language difficulty, and learning difficulty. In this paper, we interest in those special needs persons who can use e-commerce and how to model a system that can help them to joy and easy to join with e-commerce. For some, this intelligent e-commerce is not only for shopping only but will become part of their healing for special needs in order to engage with daily human activities and increase their daily confidence in life. This paper also a preliminary investigation that can be used for Ph.D. or Doctoral research degree who is interested in building e-commerce framework for people with a special need or disability.

关键词： Companies Machine learning Speech recognition Tools Pricing