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Pruritus and Its Association With Cancer and Mortality in Dermatomyositis and Polymyositis: A Nationwide Cohort Study in Taiwan From 2005 to 2022

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Dermatologic Therapy 2025年第1期2025卷

作者： Der-Jr Huang Yu-Hsuan Joni Shao Yi-Hsien Shih Woan-Ruoh Lee Ling-Ya Huang Yu-Min Kuo Quoc Thao Trang Pham Hao-Jui Weng Department of Dermatology Taipei Medical University-Shuang Ho Hospital New Taipei City Taiwan shh.org.tw Graduate Institute of Biomedical Informatics College of Medical Science and Technology Taipei Medical University Taipei Taiwan tmu.edu.tw Clinical Big Data Research Center Taipei Medical University Hospital Taipei Taiwan tmuh.org.tw Health Data Analytics and Statistics Center Office of Data Science Taipei Medical University Taipei Taiwan tmu.edu.tw Department of Dermatology School of Medicine College of Medicine Taipei Medical University Taipei Taiwan tmu.edu.tw Graduate Institute of Medical Sciences College of Medicine Taipei Medical University Taipei Taiwan tmu.edu.tw Division of Allergy Immunology and Rheumatology Department of Internal Medicine National Taiwan University Hospital and National Taiwan University Taipei Taiwan ntu.edu.tw Graduate Institute of Clinical Medicine College of Medicine National Taiwan University Taipei Taiwan ntu.edu.tw International Ph.D. Program in Cell Therapy and Regenerative Medicine College of Medicine Taipei Medical University Taipei Taiwan tmu.edu.tw Department of Dermatology Faculty of Medicine University of Medicine and Pharmacy at Ho Chi Minh City Ho Chi Minh City Vietnam hcmut.edu.vn Graduate Institute of Clinical Medicine College of Medicine Taipei Medical University Taipei Taiwan medcol.mw

Background: Pruritus is the most common initial symptom reported by patients with dermatomyositis (DM) and polymyositis (PM). However, there is limited data regarding the impact of pruritus on cancer and mortality in patients with DM and PM. In this study, we aimed to investigate how pruritus is associated with cancer and mortality in patients with DM and PM. Methods: This nationwide, population-based retrospective cohort study included adult DM and PM patients from Taiwan’s National Health Insurance Research Database between 2005 and 2022. Sex- and age-matched pruritic patients, identified by over 6 weeks of antipruritic medication use, and nonpruritic patients were analyzed. The primary outcome was cancer occurrence or all-cause mortality. The association between pruritus and these outcomes was estimated using Cox proportional hazards models. Results: Among 919 matched pairs of pruritic and nonpruritic patients, cancer was observed in 19.96% in the long-term pruritic group (LPG), 14.63% in the short-term pruritic group (SPG), and 10.34% in the non-pruritic group (NPG) ( p < 0.0001). All-cause mortality was documented as 30.37% in the LPG, 29.69% in the SPG, and 37.76% in the NPG ( p < 0.0001). After adjusting for sex, age, and other comorbidities, pruritus was associated with an increased risk of cancer (hazard ratio (HR) 1.708, 95% confidence interval (CI) 1.229–2.374) and a lower risk of all-cause mortality (HR 0.483, 95% CI 0.409–0.569). Conclusion: This population-based study revealed that pruritus appeared to be associated with increased risks of cancer and decreased all-cause mortality. Thus, pruritus may serve as a pragmatic factor for risk stratification and tailored treatment strategies in DM and PM. Cancer screening, particularly for nasopharyngeal and breast cancers in East Asian populations, is recommended for patients with DM or PM, especially those presenting with pruritus. Meanwhile, patients without pruritus may require vigilant management for pote

关键词： cancer dermatomyositis idiopathic inflammatory myopathies mortality polymyositis pruritus

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Quantifying quantumness of channels without entanglement

arXiv

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arXiv 2021年

作者： Ku, Huan-Yu Kadlec, Josef Černoch, Antonín Quintino, Marco Túlio Zhou, Wenbin Lemr, Karel Lambert, Neill Miranowicz, Adam Chen, Shin-Liang Nori, Franco Chen, Yueh-Nan National Cheng Kung University Tainan701 Taiwan Theoretical Quantum Physics Laboratory RIKEN Cluster for Pioneering Research Saitama Wako-shi351-0198 Japan Palacký University in Olomouc Faculty of Science Joint Laboratory of Optics Palacký University Institute of Physics AS CR 17. listopadu 12 Olomouc771 46 Czech Republic Institute of Physics The Czech Academy of Sciences Joint Laboratory of Optics of PU and IP AS CR 17. listopadu 50A Olomouc772 07 Czech Republic Faculty of Physics University of Vienna Boltzmanngasse 5 Vienna1090 Austria Austrian Academy of Sciences Boltzmanngasse 3 ViennaA-1090 Austria Graduate School of Informatics Nagoya University Chikusa-ku Nagoya464-8601 Japan Institute of Spintronics and Quantum Information Faculty of Physics Adam Mickiewicz University Poznan61-614 Poland Department of Physics National Chung Hsing University Taichung40227 Taiwan Dahlem Center for Complex Quantum Systems Freie Universität Berlin Berlin14195 Germany RIKEN Center for Quantum Computing Saitama Wako351-0198 Japan Department of Physics The University of Michigan Ann ArborMI48109-1040 United States

Quantum channels breaking entanglement, incompatibility, or nonlocality are defined as such because they are not useful for entanglement-based, one-sided device-independent, or device-independent quantum information processing, respectively. Here, we show that such breaking channels are related to complementary tests of macrorealism i.e., temporal separability, channel unsteerability, temporal unsteerability, and the temporal Bell inequality. To demonstrate this we first define a steerability-breaking channel, which is conceptually similar to entanglement and nonlocality-breaking channels and prove that it is identical to an incompatibility-breaking channel. A hierarchy of quantum non-breaking channels is derived, akin to the existing hierarchy relations for temporal and spatial quantum correlations. We then introduce the concept of channels that break temporal correlations, explain how they are related to the standard breaking channels, and prove the following results: (1) A robustness-based measure for non-entanglement-breaking channels can be probed by temporal nonseparability. (2) A non-steerability-breaking channel can be quantified by channel steering. (3) Temporal steerability and non-macrorealism can be used for, respectively, distinguishing unital steerability-breaking channels and nonlocality-breaking channels for a maximally entangled state. Finally, a two-dimensional depolarizing channel is experimentally implemented as a proof-of-principle example to demonstrate the hierarchy relation of non-breaking channels using temporal quantum correlations. Copyright © 2021, The Authors. All rights reserved.

关键词： Quantum entanglement

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Publisher Correction: Statistically and functionally fine-mapped blood eQTLs and pQTLs from 1,405 humans reveal distinct regulation patterns and disease relevance

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Nature genetics 2024年第10期56卷 2281页

作者： Qingbo S Wang Takanori Hasegawa Ho Namkoong Ryunosuke Saiki Ryuya Edahiro Kyuto Sonehara Hiromu Tanaka Shuhei Azekawa Shotaro Chubachi Yugo Takahashi Saori Sakaue Shinichi Namba Kenichi Yamamoto Yuichi Shiraishi Kenichi Chiba Hiroko Tanaka Hideki Makishima Yasuhito Nannya Zicong Zhang Rika Tsujikawa Ryuji Koike Tomomi Takano Makoto Ishii Akinori Kimura Fumitaka Inoue Takanori Kanai Koichi Fukunaga Seishi Ogawa Seiya Imoto Satoru Miyano Yukinori Okada Department of Genome Informatics Graduate School of Medicine University of Tokyo Tokyo Japan. qingbow@m.u-tokyo.ac.jp. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. qingbow@m.u-tokyo.ac.jp. M&D Data Science Center Tokyo Medical and Dental University Tokyo Japan. Department of Infectious Diseases Keio University School of Medicine Tokyo Japan. hounamugun@keio.jp. Department of Pathology and Tumor Biology Kyoto University Kyoto Japan. Department of Statistical Genetics Osaka University Graduate School of Medicine Suita Japan. Department of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Suita Japan. Department of Genome Informatics Graduate School of Medicine University of Tokyo Tokyo Japan. Division of Pulmonary Medicine Department of Medicine Keio University School of Medicine Tokyo Japan. Faculty of Medicine Osaka University Suita Japan. Center for Data Sciences Brigham and Women's Hospital Harvard Medical School Boston MA USA. Divisions of Genetics and Rheumatology Department of Medicine Brigham and Women's Hospital Harvard Medical School Boston MA USA. Program in Medical and Population Genetics Broad Institute of MIT and Harvard Cambridge MA USA. Laboratory of Children's Health and Genetics Division of Health Science Osaka University Graduate School of Medicine Suita Japan. Department of Pediatrics Osaka University Graduate School of Medicine Suita Japan. Division of Genome Analysis Platform Development National Cancer Center Research Institute Tokyo Japan. Institute for the Advanced Study of Human Biology (WPI-ASHBi) Kyoto University Kyoto Japan. Health Science Research and Development Center (HeRD) Tokyo Medical and Dental University Tokyo Japan. Laboratory of Veterinary Infectious Disease Department of Veterinary Medicine Kitasato University Tokyo Japan. Department of Respiratory Medicine Nagoya University Graduate School of Medicine Nagoya Japan. In

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Evidence of hadronic origin of the gamma-ray emission from the nova RS Oph by the MAGIC telescopes 38

Evidence of hadronic origin of the gamma-ray emission from t...

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38th International Cosmic Ray Conference, ICRC 2023

作者： Green, David M. Ramazani, Vandad Fallah Leone, Francesco López-Coto, Rubén López-Oramas, Alicia Sitarek, Julian Abe, H. Abe, S. Abhir, J. Acciari, V.A. Agudo, I. Aniello, T. Ansoldi, S. Antonelli, L.A. Arbet Engels, A. Arcaro, C. Artero, M. Asano, K. Baack, D. Babić, A. Baquero, A. Barres de Almeida, U. Barrio, J.A. Batković, I. Baxter, J. Becerra González, J. Bednarek, W. Bernardini, E. Bernardos, M. Bernete, J. Berti, A. Besenrieder, J. Bigongiari, C. Biland, A. Blanch, O. Bonnoli, G. Bošnjak, Ž. Burelli, I. Busetto, G. Campoy-Ordaz, A. Carosi, A. Carosi, R. Carretero-Castrillo, M. Castro-Tirado, A.J. Ceribella, G. Chai, Y. Chilingarian, A. Cifuentes, A. Cikota, S. Colombo, E. Contreras, J.L. Cortina, J. Covino, S. D’Amico, G. D’Elia, V. Da Vela, P. Dazzi, F. De Angelis, A. De Lotto, B. Del Popolo, A. Delfino, M. Delgado, J. Delgado Mendez, C. Depaoli, D. Di Pierro, F. Di Venere, L. Dominis Prester, D. Donini, A. Dorner, D. Doro, M. Elsaesser, D. Emery, G. Escudero, J. Fallah Ramazani, V. Fariña, L. Fattorini, A. Foffano, L. Font, L. Fröse, S. Fukami, S. Fukazawa, Y. García López, R.J. Garczarczyk, M. Gasparyan, S. Gaug, M. Giesbrecht Paiva, J.G. Giglietto, N. Giordano, F. Gliwny, P. Godinović, N. Grau, R. Green, D. Green, J.G. Hadasch, D. Hahn, A. Hassan, T. Heckmann, L. Herrera, J. Hrupec, D. Hütten, M. Imazawa, R. Inada, T. Iotov, R. Ishio, K. Jiménez Martínez, I. Jormanainen, J. Kerszberg, D. Kluge, G.W. Kobayashi, Y. Kouch, P.M. Kubo, H. Kushida, J. Láinez Lezáun, M. Lamastra, A. Lelas, D. Leone, F. Lindfors, E. Linhoff, L. Lombardi, S. Longo, F. López-Coto, R. López-Moya, M. López-Oramas, A. Loporchio, S. Lorini, A. Lyard, E. Machado de Oliveira Fraga, B. Majumdar, P. Makariev, M. Maneva, G. Mang, N. Manganaro, M. Mangano, S. Mannheim, K. Mariotti, M. Martínez, M. Martínez-Chicharro, M. Mas-Aguilar, A. Mazin, D. Menchiari, S. Mender, S. Mićanović, S. Miceli, D. Miener, T. Miranda, J.M. Mirzoyan, R. Bochum Germany Instituto de Astrofísica de Andalucía-CSIC Granada Spain Instituto de Astrofísica de Canarias Departamento de Astrofísica Universidad de La Laguna La Laguna Spain Department of Astrophysics Faculty of Physics and Applied Informatics University of Lodz Lodz Poland The University of Tokyo Chiba Kashiwa277-8582 Japan ETH Zürich ZürichCH-8093 Switzerland Instituto de Astrofísica de Canarias Dpto. de Astrofísica Universidad de La Laguna Tenerife La LagunaE-38200 Spain Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n Granada18008 Spain RomeI-00136 Italy Università di Udine INFN Trieste UdineI-33100 Italy Università di Padova INFN PadovaI-35131 Italy Bellaterra BarcelonaE-08193 Spain Technische Universität Dortmund DortmundD-44221 Germany Zagreb10000 Croatia IPARCOS Institute EMFTEL Department Universidad Complutense de Madrid MadridE-28040 Spain URCA RJ Rio de Janeiro22290-180 Brazil University of Lodz Faculty of Physics and Applied Informatics Department of Astrophysics Lodz90-236 Poland Centro de Investigaciones Energéticas Medioambientales y Tecnológicas MadridE-28040 Spain Departament de Física CERES-IEEC Universitat Autònoma de Barcelona BellaterraE-08193 Spain Università di Pisa INFN Pisa PisaI-56126 Italy Universitat de Barcelona ICCUB IEEC-UB BarcelonaE-08028 Spain Armenian MAGIC Group A. Alikhanyan National Science Laboratory Yerevan0036 Armenia Department for Physics and Technology University of Bergen Norway INFN MAGIC Group INFN Sezione di Catania Dipartimento di Fisica e Astronomia University of Catania CataniaI-95123 Italy INFN MAGIC Group INFN Sezione di Torino Università degli Studi di Torino TorinoI-10125 Italy INFN MAGIC Group INFN Sezione di Bari Dipartimento Interateneo di Fisica dell’Università e del Politecnico di Bari BariI-70125 Italy Croatian MAGIC Group University of Rijeka Faculty of Physics Rijeka51000 Croatia Universität Würzburg Würzbu

RS Ophiuchi (RS Oph) is a symbiotic recurrent nova that shows eruptive events roughly every 15 years. On August 8th, 2021, RS Oph erupted with its latest outburst. This event was detected by a wide range of multi-wavelength (MWL) instruments from radio up to very-high-energy (VHE) gamma rays. The MAGIC telescopes followed up on optical and high-energy triggers and initiated an observation campaign from August 9th till September 1st. RS Oph is the first nova detected in the VHE gamma-ray energy range. We report on the detection of VHE gamma rays at a significant level of 13.2σ during the first 4 days of RS Oph with the MAGIC telescopes. We combine the VHE emission detected by MAGIC with optical and high energy observations and conclude RS Oph accelerated hadrons during its eruption. We will present the MWL modeling revealing this hadronic emission, and its further implications for Galactic cosmic-rays. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Hadrons

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SCUBA-2 Ultra Deep Imaging EAO Survey (STUDIES). V. Confusion-limited Submillimeter Galaxy Number Counts at 450 µm and Data Release for the COSMOS Field

arXiv

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arXiv 2024年

作者： Gao, Zhen-Kai Lim, Chen-Fatt Wang, Wei-Hao Chen, Chian-Chou Smail, Ian Chapman, Scott C. Zheng, Xian Zhong Shim, Hyunjin Kodama, Tadayuki Ao, Yiping Chang, Siou-Yu Clements, David L. Dunlop, James S. Ho, Luis C. Hsu, Yun-Hsin Hwang, Chorng-Yuan Hwang, Ho Seong Koprowski, M.P. Scott, Douglas Serjeant, Stephen Toba, Yoshiki Urquhart, Sheona A. No. 1 Section 4 Roosevelt Rd. Taipei10617 Taiwan Graduate Institute of Astronomy National Central University 300 Zhongda Road Zhongli Taoyuan32001 Taiwan Centre for Extragalactic Astronomy Department of Physics Durham University South Road DurhamDH1 3LE United Kingdom Department of Physics and Atmospheric Science Dalhousie University Halifax HalifaxNSB3H 3J5 Canada Purple Mountain Observatory Key Laboratory for Radio Astronomy Chinese Academy of Sciences 10 Yuanhua Road Nanjing210023 China School of Astronomy and Space Science University of Science and Technology of China Anhui Hefei230026 China Department of Earth Science Education Kyungpook National University 80 Daehak-ro Buk-gu Daegu41566 Korea Republic of Astronomical Institute Tohoku University 6-3 Aramaki Aoba Miyagi Sendai980-8578 Japan Institute of Astronomy Department of Physics National Tsing Hua University Hsinchu30013 Taiwan Imperial College London Blackett Laboratory Prince Consort Road LondonSW7 2AZ United Kingdom SUPA Institute for Astronomy University of Edinburgh Royal Observatory EdinburghEH9 3HJ United Kingdom Kavli Institute for Astronomy and Astrophysics Peking University Beijing100871 China Department of Astronomy School of Physics Peking University Beijing100871 China Department of Philosophy National Taiwan University No. 1 Section 4 Roosevelt Rd. Taipei10617 Taiwan Astronomy Program Department of Physics and Astronomy Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of SNU Astronomy Research Center Seoul National University 1 Gwanak-ro Gwanak-gu Seoul08826 Korea Republic of Institute of Astronomy Faculty of Physics Astronomy and Informatics Nicolaus Copernicus University Grudziadzka 5 Torun87-100 Poland Department of Physics and Astronomy University of British Columbia 6224 Agricultural Road VancouverBCV6T 1Z1 Canada School of Physical Sciences The Open University Milton KeynesMK7 6AA United Kingdom

We present confusion-limited SCUBA-2 450-µm observations in the COSMOS-CANDELS region as part of the JCMT Large program, SCUBA-2 Ultra Deep Imaging EAO Survey (STUDIES). Our maps at 450 and 850 µm cover an area of 450 arcmin2. We achieved instrumental noise levels of σ450 = 0.59 mJy beam−1 and σ850 = 0.09 mJy beam−1 in the deepest area of each map. The corresponding confusion noise levels are estimated to be 0.65 and 0.36 mJy beam−1. Above the 4 (3.5) σ threshold, we detected 360 (479) sources at 450 µm and 237 (314) sources at 850 µm. We derive the deepest blank-field number counts at 450 µm, covering the flux-density range of 2 to 43 mJy. These are in agreement with other SCUBA-2 blank-field and lensing-cluster observations, but are lower than various model counts. We compare the counts with those in other fields and find that the field-to-field variance observed at 450 µm at the R = 6′ scale is consistent with Poisson noise, so there is no evidence of strong 2-D clustering at this scale. Additionally, we derive the integrated surface brightness at 450 µm down to 2.1 mJy to be (Equation presented) Jy deg−2, contributing to (41±4)% of the 450-µm extragalactic background light (EBL) measured by COBE and Planck. Our results suggest that the 450-µm EBL may be fully resolved at (Equation presented) mJy, which extremely deep lensing-cluster observations and next-generation submillimeter instruments with large aperture sizes may be able to achieve. © 2024, CC BY.

关键词： Galaxies

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PAD-UFES-20: a skin lesion dataset composed of patient data and clinical images collected from smartphones

arXiv

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arXiv 2020年

作者： Pacheco, Andre G.C. Lima, Gustavo R. Salomão, Amanda S. Krohling, Breno A. Biral, Igor P. de Angelo, Gabriel G. Alves, Fábio C.R. Esgario, José G.M. Simora, Alana C. Castro, Pedro B.C. Rodrigues, Felipe B. Frasson, Patricia H.L. Krohling, Renato A. Knidel, Helder Santos, Maria C.S. do Espírito Santo, Rachel B. Macedo, Telma L.S.G. Canuto, Tania R.P. de Barros, Luíz F.S. Graduate Program in Computer Science Federal University of Espirito Santo Vitoria Brazil Faculty of Medicine Federal University of Espirito Santo Vitoria Brazil Federal University of Espirito Santo Vitoria Brazil Nature Inspired Computing Laboratory Federal University of Espirito Santo Vitoria Brazil Department of Specialized Medicine Federal University of Espirito Santo Vitoria Brazil Production Engineering Department Federal University of Espirito Santo Vitoria Brazil Secretary of Health of the Espírito Santo state Governor of Espírito Santo state Vitória Brazil Federal University of Espirito Santo Vitoria Brazil

Over the past few years, different computer-aided diagnosis (CAD) systems have been proposed to tackle skin lesion analysis. Most of these systems work only for dermoscopy images since there is a strong lack of public clinical images archive available to design them. To fill this gap, we release a skin lesion benchmark composed of clinical images collected from smartphone devices and a set of patient clinical data containing up to 22 features. The dataset consists of 1,373 patients, 1,641 skin lesions, and 2,298 images for six different diagnostics: three skin diseases and three skin cancers. In total, 58.4% of the skin lesions are biopsy-proven, including 100% of the skin cancers. By releasing this benchmark, we aim to aid future research and the development of new tools to assist clinicians to detect skin cancer. Copyright © 2020, The Authors. All rights reserved.

关键词： Dermatology

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INTRODUCTION

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Bulletin of the American Meteorological Society 2024年第8期105卷 S1-S11页

作者： Boyer, T. Blunden, J. Dunn, R.J.H. NOAA/NESDIS National Centers for Environmental Information Silver Spring Maryland NOAA/NESDIS National Centers for Environmental Information Asheville North Carolina Met Office Hadley Centre Exeter United Kingdom European Centre for Medium-Range Weather Forecasts Reading United Kingdom University of Maryland College Park Maryland Scripps Institution of Oceanography University of California San Diego La Jolla California NOAA/NWS National Centers for Environmental Prediction Climate Prediction Center College Park Maryland Brandenburg University of Technology (BTU) Cottbus-Senftenberg Germany Servicio Meteorológico Nacional Buenos Aires Argentina NOAA/OAR Physical Sciences Laboratory Boulder Colorado European Centre for Medium-Range Weather Forecasts Bonn Germany Center for Geophysical Research and School of Physics University of Costa Rica San José Costa Rica Department of Meteorology and National Centre for Earth Observation University of Reading Reading United Kingdom Centro Nacional de Monitoramento e Alertas de Desastres Naturais CEMADEN São Paulo Brazil Université Grenoble Alpes Institut des Géosciences de l’Environnement IRD CNRS Grenoble INP Grenoble France Hampton University Hampton Virginia Seychelles Meteorological Authority Mahe Seychelles Section for Glaciers Ice and Snow Norwegian Water Resources and Energy Directorate Oslo Norway National Research Institute for Agriculture Food and Environment (INRAE) CARRTEL Université Savoie Mont Blanc Thonon les Bains France Graduate School of Agriculture Osaka Metropolitan University Sakai Japan Science Faculty Universidad Nacional de Colombia Bogotá Colombia University of Bremen Bremen Germany NOAA Global Monitoring Laboratory Boulder Colorado Servicio Nacional de Meteorología e Hidrología del Perú Lima Perú Centro de Investigaciones sobre Desertificación – Spanish National Research Council (CSIC-UV-GVA) Valencia Spain Hydro-Climate Extremes Lab (H-CEL) Ghent University Ghent Belgium Department o

In 2023, La Niña conditions that generally prevailed in the eastern Pacific Ocean from mid-2020 into early 2023 gave way to a strong El Niño by October. Atmospheric concentrations of Earth’s major greenhouse gases—carbon dioxide, methane, and nitrous oxide—all increased to record-high levels. The annual global average carbon dioxide concentration in the atmosphere rose to 419.3±0.1 ppm, which is 50% greater than the pre-industrial level. The growth from 2022 to 2023 was 2.8 ppm, the fourth highest in the record since the 1960s. The combined short-term effects of El Niño and the long-term effects of increasing levels of heat-trapping gases in the atmosphere contributed to new records for many essential climate variables reported here. The annual global temperature across land and oceans was the highest in records dating as far back as 1850, with the last seven months (June–December) having each been record warm. Over land, the globally averaged temperature was also record high. Dozens of countries reported record or near-record warmth for the year, including China and continental Europe as a whole (warmest on record), India and Russia (second warmest), and Canada (third warmest). Intense and widespread heatwaves were reported around the world. In Vietnam, an all-time national maximum temperature record of 44.2°C was observed at Tuong Duong on 7 May, surpassing the previous record of 43.4°C at Huong Khe on 20 April 2019. In Brazil, the air temperature reached 44.8°C in Araçuaí in Minas Gerais on 20 November, potentially a new national record and 12.8°C above normal. The effect of rising temperatures was apparent in the cryosphere, where snow cover extent by June 2023 was the smallest in the 56-year record for North America and seventh smallest for the Northern Hemisphere overall. Heatwaves contributed to the greatest average mass balance loss for Alpine glaciers around the world since the start of the record in 1970. Due to rapid volume loss beginning in 2021, St. A

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Implementation of Mobile game for Religion Learning

Implementation of Mobile game for Religion Learning

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IEEE International Conference on Teaching, Assessment and Learning for Engineering (TALE)

作者： Edy Sulistiyo Vindy Nizirwan Anwar Diana Teresia Spits Warnars Setya Chendra Wibawa Goenawan Brotosaputro Dedy Prasetya Kristiadi Harco Leslie Hendric Spits Warnars Kiyota Hashimoto Electrical Engineering Department Universitas Negeri Surabaya Jawa Timur Indonesia Game Application & Technology Program School of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Computer Science Esa Unggul University Jakarta Indonesia Information Systems Department Bina Nusantara University Jakarta Indonesia Informatics Department Universitas Negeri Surabaya Jawa Timur Indonesia Information System Department Universitas Budi Luhur Jakarta Indonesia Computer Science department Raharja University Tangerang Indonesia Computer Science Department BINUS Graduate Program – Doctor of Computer Science Bina Nusantara University Jakarta Indonesia Faculty of Technology and Environment Prince Songkla University Phuket Campus Thailand

ISBN: (数字)9781728126654

ISBN: (纸本)9781728126661

Currently, the growth of information and technology is rapid. It makes a lot of things in various fields including education becoming more effective and efficient. In education, one of its implementation which is a game is proven to be a useful tool to support conventional teaching methods and bring a more natural understanding of learning materials. Moreover, as a product of the popular culture in modern society, video game mirrors the general culture practice in real life and reflects it via its own culture inside the game. This makes a video game can give a contribution to the social construction of reality as it affects the player's view towards learning in real life and vice versa. From there, we see that there is an opportunity for learning about religion to be supported by its utilization to provide an interactive and fun learning experience. In this paper, we discuss how a video game is implemented to support religious learning. The game was developed with the scrum method where we surveyed to gather the user requirements before the design step. The game design was made by using the use case diagram and storyboard, and it was built using Unity version 2017.3.0f3.

关键词： Games Land mobile radio Education Computer science Operating systems Information systems Media

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Generation of terahertz transients from Co2Fe0.4Mn0.6Si-Heusler-alloy/normal-metal nanobilayers excited by femtosecond optical pulses

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Physical Review Research 2021年第4期3卷 043025-043025页

作者： Sarah Heidtfeld Roman Adam Takahide Kubota Koki Takanashi Derang Cao Carolin Schmitz-Antoniak Daniel E. Bürgler Fangzhou Wang Christian Greb Genyu Chen Ivan Komissarov Hilde Hardtdegen Martin Mikulics Roman Sobolewski Shigemasa Suga Claus M. Schneider Research Centre Jülich Peter Grünberg Institute 52425 Jülich Germany Faculty of Physics University of Duisburg-Essen 47048 Duisburg Germany Institute for Materials Research Tohoku University Sendai 980-8577 Japan Center for Spintronics Research Network Tohoku University Sendai 980-8577 Japan Center for Science and Innovation in Spintronics (Core Research Cluster) Tohoku University Sendai 980-8577 Japan College of Physics National Demonstration Center for Experimental Applied Physics Education Qingdao University Qingdao 266071 China Materials Science Graduate Program University of Rochester Rochester New York 14627 USA Laboratory for Laser Energetics University of Rochester Rochester New York 14623 USA Department of Electrical and Computer Engineering University of Rochester Rochester New York 14627 USA Belarusian State University of Informatics and Radioelectronics Minsk 220013 Belarus Research Centre Jülich Ernst Ruska Centre for Microscopy and Spectroscopy with Electrons 52425 Jülich Germany Department of Physics and Astronomy University of Rochester Rochester New York 14627 USA The Institute of Scientific and Industrial Research Osaka University Ibaraki Osaka 567-0047 Japan Department of Physics University of California Davis Davis California 95616 USA

We generated pulses of electromagnetic radiation in the terahertz (THz) frequency range by optical excitation of Co2Fe0.4Mn0.6Si (CFMS)/normal-metal (NM) bilayer structures. The CFMS is a Heusler alloy showing a band gap in one spin channel and is therefore a half metal. We compared the THz emission efficiency in a systematic manner for four different CFMS/NM bilayers, where NM was either Pt, Ta, Cr, or Al. Our measurements show that the THz intensity is highest for a Pt capping. We also demonstrate the tunability of the THz amplitude by varying the magnetic field for all four bilayers. We attribute the THz generation to the inverse spin Hall effect. In order to investigate the role of the interface in THz generation, we measured the spin mixing conductance for each CFMS/NM bilayer using a ferromagnetic resonance method. We found that the spin-orbit coupling cannot completely describe the THz generation in the bilayers and that the spin transmission efficiency of the CFMS/NM interface and the spin diffusion length, as well as the oxidation of the NM layer, play crucial roles in the THz emission process.

关键词： Inverse spin Hall effect Magnetism Spin injection Spin pumping Spintronics Ferromagnetic resonance Terahertz time-domain spectroscopy

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The Potential of Generative Artificial Intelligence Across Disciplines: Perspectives and Future Directions

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The Journal of Data Education 2025年第1期65卷

作者： Keng-Boon Ooi Garry Wei-Han Tan Mostafa Al-Emran Mohammed A. Al-Sharafi Alexandru Capatina Amrita Chakraborty Yogesh K. Dwivedi Tzu-Ling Huang Arpan Kumar Kar Voon-Hsien Lee Xiu-Ming Loh Adrian Micu Patrick Mikalef Emmanuel Mogaji Neeraj Pandey Ramakrishnan Raman Nripendra P. Rana Prianka Sarker Anshuman Sharma Ching-I Teng Samuel Fosso Wamba Lai-Wan Wong a UCSI Graduate Business School UCSI University Kuala Lumpur Malaysiab FORE School of Management New Delhi Indiac Faculty of Business Design and Arts Swinburne University of Technology Sarawak Campus Kuching Malaysia a UCSI Graduate Business School UCSI University Kuala Lumpur Malaysiac Faculty of Business Design and Arts Swinburne University of Technology Sarawak Campus Kuching Malaysiad College of Business Administration Adamson University Manila Philippines e Faculty of Engineering & IT The British University in Dubai Dubai UAEf Department of Computer Techniques Engineering Dijlah University College Baghdad Iraq g Institute of Informatics and Computing in Energy Universiti Tenaga Nasional Selangor Malaysia h Department of Business Administration “Dunarea de Jos” University of Galati Galati Romania i Tech Talk New Delhi India j Digital Futures for Sustainable Business & Society Research Group School of Management Swansea University Bay Campus Swansea UKk Department of Management Symbiosis International (Deemed University) Pune India l Department of Information Management National Central University Taoyuan Taiwan m Department of Management Studies Indian Institute of Technology Delhi New Delhi India n Faculty of Business and Finance Universiti Tunku Abdul Rahman Kampar Malaysia o Faculty of Information Technology and Electrical Engineering Norwegian University of Science and Technology Trondheim Norwayp Department of Technology Management SINTEF Digital Trondheim Norway q Keele Business School Keele University Keele UK r Indian Institute of Management Mumbai Mumbai India k Department of Management Symbiosis International (Deemed University) Pune India s College of Business and Economics Qatar University Doha Qatar t Business School Manchester Metropolitan University Manchester UK u Department of Marketing College of Business Administration Ajman university Ajman UAE v Graduate Institute of Management Chang Gung University Taoyuan Taiw

ABSTRACTIn a short span of time since its introduction, generative artificial intelligence (AI) has garnered much interest at both personal and organizational levels. This is because of its potential to cause drastic and widespread shifts in many aspects of life that are comparable to those of the Internet and smartphones. More specifically, generative AI utilizes machine learning, neural networks, and other techniques to generate new content (e.g. text, images, music) by analyzing patterns and information from the training data. This has enabled generative AI to have a wide range of applications, from creating personalized content to improving business operations. Despite its many benefits, there are also significant concerns about the negative implications of generative AI. In view of this, the current article brings together experts in a variety of fields to expound and provide multi-disciplinary insights on the opportunities, challenges, and research agendas of generative AI in specific industries (i.e. marketing, healthcare, human resource, education, banking, retailing, the workplace, manufacturing, and sustainable IT management).

关键词： Generative artificial intelligence machine learning large language model ChatGPT Bard

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