Cancer, a leading cause of death globally, occurs due to genomic changes and manifests heterogeneously across patients. To advance research on personalized treatment strategies, the effectiveness of various drugs on c...
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Cancer, a leading cause of death globally, occurs due to genomic changes and manifests heterogeneously across patients. To advance research on personalized treatment strategies, the effectiveness of various drugs on cells derived from cancers (‘cell lines') is experimentally determined in laboratory settings. Nevertheless, variations in the distribution of genomic data and drug responses between cell lines and humans arise due to biological and environmental differences. Moreover, while genomic profiles of many cancer patients are readily available, the scarcity of corresponding drug response data limits the ability to train machine learning models that can predict drug response in patients effectively. Recent cancer drug response prediction methods have largely followed the paradigm of unsupervised domain-invariant representation learning followed by a downstream drug response classification step. Introducing supervision in both stages is challenging due to heterogeneous patient response to drugs and limited drug response data. This paper addresses these challenges through a novel representation learning method in the first phase and weak supervision in the second. Experimental results on real patient data demonstrate the efficacy of our method WISER (Weak supervISion and supErvised Representation learning) over state-of-the-art alternatives on predicting personalized drug response. Our implementation is available at https://***/kyrs/WISER. Copyright 2024 by the author(s)
The emerging technology of deepfake video poses significant threats to information integrity and public trust. Deepfake videos come in various forms, including face swaps, lip-syncing, and full-body simulations. Detec...
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Object Detection is the task of localization and classification of objects in a video or *** recent times,because of its widespread applications,it has obtained more *** the modern world,waste pollution is one signifi...
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Object Detection is the task of localization and classification of objects in a video or *** recent times,because of its widespread applications,it has obtained more *** the modern world,waste pollution is one significant environmental *** prominence of recycling is known very well for both ecological and economic reasons,and the industry needs higher *** object detection utilizing deep learning(DL)involves training a machine-learning method to classify and detect various types of waste in videos or *** technology is utilized for several purposes recycling and sorting waste,enhancing waste management and reducing environmental *** studies of automatic waste detection are difficult to compare because of the need for benchmarks and broadly accepted standards concerning the employed data ***,this study designs an Entropy-based Feature Fusion using Deep Learning forWasteObject Detection and Classification(EFFDL-WODC)*** presented EFFDL-WODC system inherits the concepts of feature fusion and DL techniques for the effectual recognition and classification of various kinds of waste *** the presented EFFDL-WODC system,two major procedures can be contained,such as waste object detection and waste object *** object detection,the EFFDL-WODC technique uses a YOLOv7 object detector with a fusionbased backbone *** addition,entropy feature fusion-based models such as VGG-16,SqueezeNet,and NASNetmodels are ***,the EFFDL-WODC technique uses a graph convolutional network(GCN)model performed for the classification of detected waste *** performance validation of the EFFDL-WODC approach was validated on the benchmark *** comprehensive comparative results demonstrated the improved performance of the EFFDL-WODC technique over recent approaches.
With the growing popularity of the Internet, Web applications have become increasingly essential in our daily lives. Web application programming interfaces (Web APIs) play a crucial role in facilitating interaction be...
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Cloud computing contains large-scale tasks and resources. Currently, the local search is a considerable choice in ensuring both computational complexity and optimization. Based on our previous research on multi-route ...
Cloud computing contains large-scale tasks and resources. Currently, the local search is a considerable choice in ensuring both computational complexity and optimization. Based on our previous research on multi-route search algorithm to reduce makespan, we apply BFDO and LPTO algorithms to address load balancing and bin-packing problems. Through abundant experiments, we validate the superiority of our proposed BFDO and LPTO.
Cloud computing environment is becoming increasingly complex due to its large-scale information growth and increasing heterogeneity of computing resources. Hierarchical Cloud computing dividing the system into multi-l...
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Cloud computing environment is becoming increasingly complex due to its large-scale information growth and increasing heterogeneity of computing resources. Hierarchical Cloud computing dividing the system into multi-levels with multiple subsystems to support the adaptability to abundant requests from users has been widely applied and brings great challenges to resource scheduling. It is critical to find an effective way to address the complex scheduling problems in hierarchical Cloud computing, whose scenarios and optimization objectives often change with the types of subsystems. In this paper, we propose a scheduling framework to select the scheduling algorithms (SFSSA) for different scheduling scenarios considering no algorithm well suitable to all scenarios. To concretize SFSSA, we propose deep learning-based algorithms selectors (DLS) trained by labeled data and deep reinforcement learning-based algorithms selectors (DRLS) trained by feedback from dynamic scenarios to complete the algorithms selection regarding the scheduling algorithms as selectable tools. Then, we apply strategies including pre-trained model, long experience reply and joint training to improve the performance of DRLS. To enable the quantitative comparison of selectors, we introduce a weighted cost model for the trade-off between solution and complexity. Through multiple sets of experiments in hierarchical Cloud computing with multi subsystems for five types of scheduling problems and varying weights of cost, we demonstrate DLS and DRLS outperform baseline strategies. Compared with random selector, greedy selector, round-robin selector, single best selector, virtual best selector and single fast selector, DLS reduces the cost by 47.4%, 46.1%, 33.9%, 47.9%, 19.3%, 18.8% under stable parameter ranges, and DRLS reduces the cost by 41.1%, 40.6%, 11.7%, 42.3%, 11.5%, 12.5% in dynamic scenarios respectively. In experiments, we also validate DRLS has stronger adaptability than DLS in dynamic schedulin
The integration of Artificial Intelligence (AI) into educational technologies marks a significant shift in learning methodologies and operational dynamics within educational institutions. At the forefront is an AI-dri...
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The concept of using natural language instead of SQL queries formed the basis of a new type of data processing called Natural Language Interface to Database (NLIDB). This paper considers a neural network (NN) approach...
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ISBN:
(数字)9798331542634
ISBN:
(纸本)9798331542641
The concept of using natural language instead of SQL queries formed the basis of a new type of data processing called Natural Language Interface to Database (NLIDB). This paper considers a neural network (NN) approach for the NLIDB systems development. Its essence is the transformation of the input text sequence specified by the user in natural language into commands in SQL, which is inherent in text-to-SQL and sequence-to-sequence tasks. The Transformer model architecture of the NN was justified in the research. This architecture allows the NN to convert an input sequence (such as a natural language text query) into an output sequence (translated into SQL format text query). WikiSQL dataset was used for NN learning and testing. Numerous experiments were conducted in order to determine the optimal parameters of the NN model were conducted. Bilingual Evaluation Understanding (BLEU) metric was used as a metric for evaluating the quality of converting an input text sequence to SQL queries. The BLEU metric for the neural network model trained on the WikiSQL sample is 56%.
5G is considered as a key contributor and infrastructure supplier in the communication technology industry, capable of supporting a wide range of services such as virtual reality, driverless automobiles, e-health, and...
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