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检索条件"机构=Concurrently with the Harvard-MIT Program in Health Sciences and Technology"
192 条 记 录,以下是11-20 订阅
排序:
Lyra: An Efficient and Expressive Subquadratic Architecture for Modeling Biological Sequences
arXiv
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arXiv 2025年
作者: Ramesh, Krithik Siddiqui, Sameed M. Gu, Albert mitzenmacher, Michael D. Sabeti, Pardis C. Broad Institute of MIT and Harvard CambridgeMA02142 United States Massachusetts Institute of Technology CambridgeMA02139 United States Computational and Systems Biology Program Massachusetts Institute of Technology CambridgeMA02139 United States Machine Learning Department Carnegie Mellon University PittsburgPA15213 United States School of Engineering and Applied Sciences Harvard University CambridgeMA02138 United States Department of Organismic and Evolutionary Biology Harvard University CambridgeMA02138 United States Department of Immunology and Infectious Diseases Harvard T.H. Chan School of Public Health Harvard University BostonMA02115 United States Howard Hughes Medical Institute Chevy ChaseMD20815 United States
Deep learning architectures such as convolutional neural networks and Transformers have revolutionized biological sequence modeling, with recent advances driven by scaling up foundation and task-specific models. The c... 详细信息
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CGM-Freq: A Python Library for Frequency Domain Analysis of Continuous Glucose Monitoring Data
CGM-Freq: A Python Library for Frequency Domain Analysis of ...
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2024 IEEE-EMBS International Conference on Biomedical and health Informatics, BHI 2024
作者: Healey, Elizabeth Kohane, Isaac Harvard-MIT Program in Health Sciences and Technology CambridgeMA United States
In recent years, the number of patients using continuous glucose monitoring (CGM) has increased. In addition to helping patients manage their disease, CGM produces time series data that can be used for integration in ... 详细信息
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AI-driven 3D Spatial Transcriptomics
arXiv
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arXiv 2025年
作者: Almagro-Pérez, Cristina Song, Andrew H. Weishaupt, Luca Kim, Ahrong Jaume, Guillaume Williamson, Drew F.K. Hemker, Konstantin Lu, Ming Y. Singh, Kritika Chen, Bowen Le, Long Phi Baras, Alexander S. Jiang, Sizun Bashashati, Ali Liu, Jonathan T.C. Mahmood, Faisal Department of Pathology Mass General Brigham Harvard Medical School BostonMA United States Cancer Program Broad Institute of Harvard and MIT CambridgeMA United States Data Science Program Dana-Farber Cancer Institute BostonMA United States Harvard-MIT Division of Health Sciences and Technology Massachusetts Institute of Technology CambridgeMA United States Department of Pathology Pusan National University Busan Korea Republic of Department of Pathology and Laboratory Medicine Emory University School of Medicine AtlantaGA United States Department of Computer Science & Technology University of Cambridge Cambridge United Kingdom Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology CambridgeMA United States Rutgers Robert Wood Johnson Medical School New BrunswickNJ United States Department of Pathology Johns Hopkins Hospital BaltimoreMD United States Department of Biomedical Engineering Johns Hopkins Hospital BaltimoreMD United States Broad Institute of Harvard and MIT CambridgeMA United States Center for Virology and Vaccine Research Beth Israel Deaconess Medical Center Harvard Medical School BostonMA United States Department of Pathology Dana Farber Cancer Institute BostonMA United States Department of Pathology and Laboratory Medicine University of British Columbia VancouverBC Canada School of Biomedical Engineering University of British Columbia VancouverBC Canada Department of Mechanical Engineering Bioengineering Laboratory Medicine & Pathology University of Washington SeattleWA United States Harvard Data Science Initiative Harvard University CambridgeMA United States
A comprehensive three-dimensional (3D) map of tissue architecture and gene expression is crucial for illuminating the complexity and heterogeneity of tissues across diverse biomedical applications1. However, most spat... 详细信息
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Raman spectroscopic investigation of gramicidin A′ conformations
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Science 1974年 第4151期185卷 616-618页
作者: Rothschild, Kenneth J. Stanley, H. Eugene Harvard-MIT Program in Health Sciences and Technology Department of Physics Massachusetts Institute of Technology Cambridge MA 02139 United States
Gramicidin A′ is believed to form transmembrane channels in lipid bilayers and biological membranes. The first Roman spectroscopic study of gramicidin A′ is presented. Evidence is found for two types of conformation...
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Transcriptional network classifiers
Transcriptional network classifiers
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作者: Chang, Hsun-Hsien Ramoni, Marco F. Childrens' Hospital Informatics Program Harvard-MIT Division of Health Sciences and Technology Harvard Medical School Boston Massachusetts United States
Background: Gene interactions play a central role in transcriptional networks. Many studies have performed genome-wide expression analysis to reconstruct regulatory networks to investigate disease processes. Since bio... 详细信息
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Model-Based Insulin Sensitivity and Beta-Cell Function Estimation from Daily Continuous Glucose Monitoring  46
Model-Based Insulin Sensitivity and Beta-Cell Function Estim...
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46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2024
作者: Healey, Elizabeth Kohane, Isaac Harvard-MIT Program in Health Sciences and Technology CambridgeMA United States Harvard Medical School Department of Biomedical Informatics BostonMA United States
Type 2 diabetes (T2D) is a prevalent chronic illness with many different options for treatment management. Continuous glucose monitors (CGM) offer physiological data that clinicians can access when making treatment de... 详细信息
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The mars gravity biosatellite: Atmospheric reconditioning strategies for extended-duration rodent life support
The mars gravity biosatellite: Atmospheric reconditioning st...
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37th International Conference on Environmental Systems, ICES 2007
作者: Fulford-Jones, Thaddeus R. F. Grosse, Emily B. Heafitz, Andrew M. Li, Richard Hoffman, Jeffrey A. Massachusetts Institute of Technology Graduate Education Medical Sciences Program Harvard-MIT Division of Health Sciences and Technology 70 Vassar Street Cambridge MA 02139 United States Massachusetts Institute of Technology United States
We present results which verify the design parameters and suggest performance capabilities/limitations of the Mars Gravity Biosatellite's proposed atmospherics control subassembly. Using a combination of benchtop ... 详细信息
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Contemporary Topics in Molecular Immunology  1
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1000年
作者: H. N. Eisen R. A. Reisfeld
Immunochemistry, recently rechristened molecular immunology, has been pre­ occupied throughout its long history with the structure and function of antibodies and the specificity of antibody-antigen reactions. Wit... 详细信息
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Inferring nonstationary gene networks from temporal gene expression data
Inferring nonstationary gene networks from temporal gene exp...
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Workshop on Signal Processing Systems
作者: Chang, Hsun-Hsien Smith, Jonathan J. Ramoni, Marco F. Children's Hospital Informatics Program Harvard-MIT Division of Health Sciences and Technology Harvard Medical School Boston MA 02115 United States Department of Mathematics Massachusetts Institute of Technology Cambridge MA 02142 United States
Reverse-engineering transcriptional networks from longitudinal expression profiles is a crucial step towards the study of gene regulatory mechanisms. Genes dynamically orchestrate to each other, the stationarity assum... 详细信息
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Regulatory T cells constrain T cells of shared specificity to enforce tolerance during infection
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Science (New York, N.Y.) 2025年 第6740期387卷 eadk3248页
作者: Klawon, David E J Pagane, Nicole Walker, Matthew T. Ganci, Nicole K. Miller, Christine H. Gai, Eric Rodriguez, Donald M. Ryan-Payseur, Bridgett K. Duncombe, Ryan K. Adams, Erin J. Maienschein-Cline, Mark Freitag, Nancy E. Germain, Ronald N. Wong, Harikesh S. Savage, Peter A. Department of Pathology University of Chicago Chicago IL United States Ragon Institute of Mass General MIT and Harvard Cambridge MA United States Program in Computational and Systems Biology Massachusetts Institute of Technology Cambridge MA United States Interdisciplinary Scientist Training Program University of Chicago Chicago IL United States Department of Microbiology and Immunology University of Illinois Chicago Chicago IL United States Department of Biochemistry and Molecular Biology University of Chicago Chicago IL United States Research Informatics Core Research Resources Center University of Illinois Chicago Chicago IL United States Department of Pharmaceutical Sciences University of Illinois Chicago Chicago IL United States Lymphocyte Biology Section Laboratory of Immune System Biology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD United States Department of Biology Massachusetts Institute of Technology Cambridge MA United States
During infections, CD4+ Foxp3+ regulatory T (Treg) cells must control autoreactive CD4+ conventional T (Tconv) cell responses against self-peptide antigens while permitting those against pathogen-derived "nonself...
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