This work attempts to approximate a linear Gaussian system with a finite-state hidden Markov model (HMM), which is found useful in solving sophisticated event-based state estimation problems. An indirect modeling appr...
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The problem of supervisor synthesis for discrete-event systems (DES) has been proven to be NP-hard. Nevertheless, state tree structures (STS) have turned out to be a computationally efficient framework to design super...
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In this work we present a strategic network formation model predicting the emergence of multigroup structures. Individuals decide to form or remove links based on the benefits and costs those connections carry;we focu...
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The extended Berkeley Packet Filter (eBPF) is a recent technology available in the Linux kernel that enables flexible data processing. However, so far the eBPF was mainly used for monitoring tasks such as memory, CPU,...
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This paper studies the robustness of policy iteration in the context of continuous-time infinite-horizon linear quadratic regulation (LQR) problem. It is shown that Kleinman’s policy iteration algorithm is inherently...
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CD8+T cells are a major prognostic determinant in solid tumors, including colorectal cancer (CRC). However, understanding how the interplay between different immune cells impacts on clinical outcome is still in its in...
CD8+T cells are a major prognostic determinant in solid tumors, including colorectal cancer (CRC). However, understanding how the interplay between different immune cells impacts on clinical outcome is still in its infancy. Here, we describe that the interaction of tumor infiltrating neutrophils expressing high levels of CD15 with CD8+T effector memory cells (TEM) correlates with tumor progression. Mechanistically, stromal cell-derived factor-1 (CXCL12/SDF-1) promotes the retention of neutrophils within tumors, increasing the crosstalk with CD8+T cells. As a consequence of the contact-mediated interaction with neutrophils, CD8+T cells are skewed to produce high levels of GZMK, which in turn decreases E-cadherin on the intestinal epithelium and favors tumor progression. Overall, our results highlight the emergence of GZMKhighCD8+TEMin non-metastatic CRC tumors as a hallmark driven by the interaction with neutrophils, which could implement current patient stratification and be targeted by novel therapeutics.
An ancient and counterintuitive phenomenon known as the Mpemba effect showcases the critical role of initial conditions in relaxation processes. How to realize and utilize this effect for speeding up relaxation is an ...
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This paper presents a distributed learning model predictive control (DLMPC) scheme for distributed linear time invariant systems with coupled dynamics and state constraints. The proposed solution method is based on an...
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Omni direction is the concept of existence of motion in every direction. Here, we have controlled the resulting vectors of individual wheels of a three wheel omni robot that are ultimately responsible for a stabilized...
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ISBN:
(纸本)9781728100173
Omni direction is the concept of existence of motion in every direction. Here, we have controlled the resulting vectors of individual wheels of a three wheel omni robot that are ultimately responsible for a stabilized motion of the robot in any direction. This phenomenon is termed as 'Holonomic Drive' and it provides higher efficiency and controllability to non-holonomic drives, when used with odometry and PID algorithms. Odometry basically is method of acquiring the real time positional data of a system in a world frame and using it for path planning. PID algorithm when applied on any system reduces the transient response and helps to attend steady state conditions with less settling time. Here, we have successfully designed and implemented the algorithms for path planning with the help of quadrature encoders and heading control of three wheel omni robot using PID, implemented on IMU(Inertial Measurement Unit).
In this paper,a PD-type iterative learning control method is proposed for a class of nonlinear discrete networked control systems with measurement signal and control signal data *** and differential items of the error...
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In this paper,a PD-type iterative learning control method is proposed for a class of nonlinear discrete networked control systems with measurement signal and control signal data *** and differential items of the error signal are employed in this method to modify the current control signal,which takes full advantage of the historical error *** data dropout is described as a stochastic and independent Bernoulli process with a given *** addition,the zero-order holding method is introduced at the data receivers of the controller and ***,the stability analysis and simulation results are performed to verify the convergence and effectiveness of the proposed method.
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