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Development of superconducting interference device based on graphene

Journal of Physics: Conference Series 2012年第4期400卷

作者： K Tsumura M Ohsugi T Hayashi E Watanabe D Tsuya S Nomura H Takayanagi International Center for Materials Nanoarchitectonics (MANA) National Institute for Materials Science (NIMS) 1-1 Namiki Tsukuba Ibaraki 305-0044 Japan Core Research for Evolutional Science and Technology Japan Science and Technology Agency 4-1-8 Honcho Kawaguchi Saitama 332-0012 Japan Research Institute for Science and Technology Tokyo University of Science 1-3 Kagurazaka Shinjuku-ku Tokyo 162-8601 Japan Interdisciplinary Laboratory for Nanoscale Science and Technology NIMS 1-2-1 Sengen Tsukuba Ibaraki 305-0047 Japan Institute of Physics University of Tsukuba 1-1 Tennodai Tsukuba Ibaraki 305-8571 Japan

We fabricated and examined the operation of graphene-based superconducting interference device (SQUID) consisting of two superconductor-single layer graphene-superconductor junctions connected in parallel on a superconducting loop made of aluminum. Current-voltage characteristic of the device exhibits supercurrent flowing through SGS junctions. Mean switching current can be modulated with the applied magnetic field periodically. Deduced oscillation period coincides well with that estimated from the device geometry, suggesting that our device works as a graphene-based SQUID.

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Hydrogel-supported skeletal muscle cell-based bioassay system

Hydrogel-supported skeletal muscle cell-based bioassay syste...

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International Symposium on Micromechatronics and Human science (MHS)

作者： Kuniaki Nagamine Shingo otani Mai Takeda Makoto Kanzaki Matsuhiko Nishizawa Department of Bioengineering and Robotics Tohoku University Sendai Japan Core Research for Evolutional Science and Technology Japan Science and Technology Agency Kawaguchi Japan Department of Biomedical Engineering Tohoku University Sendai Japan

Contractile C 2 C 12 myotube line patterns supported by a fibrin gel have been developed to afford a physiologically relevant and stable bioassay system. Myotube line patterns cultured on dish were transferred with 100% efficiency to the surface of fibrin gel sheets. We found that the myotubes supported by an elastic fibrin gel maintained their line patterns and contractile activities for a longer period of time (one week) than myotubes adhered on a conventional culture dish. The gel sheet-supported C 2 C 12 myotube micropatterns were combined with a microelectrode array chip to fabricate a skeletal muscle cell-based bioassay system. The contractile behavior of each myotube line pattern on the gel was individually controlled by localized electrical stimulation using microelectrode arrays that had been previously modified with the electropolymerized conducting polymer. We successfully demonstrated fluorescent imaging of the contraction-induced translocation of the glucose transporter, GLUT4, from intracellular vesicles to the plasma membrane of the myotubes. This device is applicable for the bioassay of contraction-induced metabolic alterations in a skeletal muscle cell.

关键词： Fluorescence Sugar Electrodes Polymers Physiology

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Agile parallel bioinformatics workflow management using Pwrake

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BMC research Notes 2011年第1期4卷 1-8页

作者： Mishima, Hiroyuki Sasaki, Kensaku Tanaka, Masahiro Tatebe, Osamu Yoshiura, Koh-Ichiro Department of Human Genetics Nagasaki University Graduate School of Biomedical Sciences Nagasaki Nagasaki 1-12-4 Sakamoto Japan Nagasaki University Global Center of Excellence Program Nagasaki Nagasaki 1-12-4 Sakamoto Japan Center for Computational Sciences University of Tsukuba Tsukuba Ibaraki 1-1-1 Tennodai Japan Core Research for Evolutional Science and Technology Japan Science and Technology Agency Kawaguchi Saitama 4-1-8 Honcho Japan Departmentent of Computer Science Graduate School of Systems and Information Engineering University of Tsukuba Tsukuba Ibaraki 1-1-1 Tennodai Japan

Background: In bioinformatics projects, scientific workflow systems are widely used to manage computational procedures. Full-featured workflow systems have been proposed to fulfil the demand for workflow management. However, such systems tend to be over-weighted for actual bioinformatics practices. We realize that quick deployment of cutting-edge software implementing advanced algorithms and data formats, and continuous adaptation to changes in computational resources and the environment are often prioritized in scientific workflow management. These features have a greater affinity with the agile software development method through iterative development phases after trial and error. Here, we show the application of a scientific workflow system Pwrake to bioinformatics workflows. Pwrake is a parallel workflow extension of Ruby's standard build tool Rake, the flexibility of which has been demonstrated in the astronomy domain. Therefore, we hypothesize that Pwrake also has advantages in actual bioinformatics workflows. Findings. We implemented the Pwrake workflows to process next generation sequencing data using the Genomic Analysis Toolkit (GATK) and Dindel. GATK and Dindel workflows are typical examples of sequential and parallel workflows, respectively. We found that in practice, actual scientific workflow development iterates over two phases, the workflow definition phase and the parameter adjustment phase. We introduced separate workflow definitions to help focus on each of the two developmental phases, as well as helper methods to simplify the descriptions. This approach increased iterative development efficiency. Moreover, we implemented combined workflows to demonstrate modularity of the GATK and Dindel workflows. Conclusions: Pwrake enables agile management of scientific workflows in the bioinformatics domain. The internal domain specific language design built on Ruby gives the flexibility of rakefiles for writing scientific workflows. Furthermore, readability

关键词： Ruby Iterative Development Agile Software Development Host Language Bioinformatics Domain

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Optical pump-probe spectroscopy of photocarriers in rubrene single crystals

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Physical Review B 2011年第7期83卷 075204-075204页

作者： Shoichi Tao Hiroyuki Matsuzaki Hirotaka Uemura Hiroyuki Yada Takafumi Uemura Jun Takeya Tatsuo Hasegawa Hiroshi Okamoto Department of Advanced Materials Science University of Tokyo Kashiwa 277-8561 Japan Photonic Research Institute National Institute of Advanced Industrial Science and Technology Tsukuba 305-8562 Japan Core Research for Evolutional Science and Technology Japan Science and Technology Agency Tokyo 102-0075 Japan Department of Chemistry Osaka University Toyonaka 560-0043 Japan

The photocarrier dynamics of rubrene, an organic molecular semiconductor, are investigated by transient absorption spectroscopy over a wide energy range (0.1−2.2 eV). By photoirradiation, we observed three kinds of absorption bands in the infrared region, which are attributable to induced absorptions of excitons, free carriers, and polarons. The results show that for photoirradiation with energies higher than ∼2.7 eV (∼0.4 eV higher than the lowest exciton energy), free carriers are photogenerated just after the photoirradiation. Some of those free carriers are stabilized as polarons and the others are relaxed to excitons. For the resonant excitation to the lowest-exciton, polarons can also be generated from the excitons. The temperature dependence of the decay dynamics of polarons reveals that polaron mobility increases with decreasing temperature, indicating bandlike transport of large polarons. Below 80 K, photocarriers are trapped by defects or impurities and their decay dynamics are dominated by the escape time from traps.

关键词： PHYSICS research SEMICONDUCTORS CRYSTALS TRANSIENTS (Electricity) POLARONS ENERGY-band theory of solids

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Comparison of dynamic fluctuation in drain current with static variability using N-MOSFETs with poly-Si/SiO2 gate stack structures

Comparison of dynamic fluctuation in drain current with stat...

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International Conference on Noise and Fluctuations (ICNF)

作者： K. Ohmori R. Hettiarachchi W. Feng T. Matsuki K. Yamada Core Research for Evolutional Science and Technology Japan Science and Technology Agency JST-CREST Japan Nanotechnology Laboratory Waseda University Shinjuku Tokyo Japan Graduate School of Pure and Applied Sciences University of Tsukuba Tsukuba Ibaraki Japan

ISBN: (纸本)9781457701894

We have revealed that the dynamic fluctuation in time, i.e., noise, of drain current (I d ) is closely related to the static variability. The current conduction mechanism such as diffusion and drift transports is a key to consistently understand the magnitude of not only the noise from a single transistor but also the static variability obtained from a number of transistors. The magnitude of fluctuation in the diffusion regime is larger than that in the drift regime, where the large number of carriers reduces the fluctuation.

关键词： Fluctuations Logic gates Noise MOSFET circuits Transistors Correlation Impurities

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Layer-dependent attentional processing by top-down signals in a visual cortical microcircuit model

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Frontiers in Computational Neuroscience 2011年 5卷 31页

作者： Wagatsuma, Nobuhiko Potjans, Tobias C. Diesmann, Markus Fukai, Tomoki RIKEN Brain Science Institute Wako Japan Japan Society for the Promotion of Science Tokyo Japan Computational and Systems Neuroscience Research Center Juelich Juelich Germany Brain and Neural Systems Team Wako Japan Albert-Ludwigs-University Freiburg Freiburg Germany Core Research of Evolutional Science and Technology Japan Science and Technology Agency Kawaguchi Japan

A vast amount of information about the external world continuously flows into the brain, whereas its capacity to process such information is limited. Attention enables the brain to allocate its resources of information processing to selected sensory inputs for reducing its computational load, and effects of attention have been extensively studied in visual information processing. However, how the microcircuit of the visual cortex processes attentional information from higher areas remains largely unknown. Here, we explore the complex interactions between visual inputs and an attentional signal in a computational model of the visual cortical microcircuit. Our model not only successfully accounts for previous experimental observations of attentional effects on visual neuronal responses, but also predicts contrasting differences in the attentional effects of top-down signals between cortical layers: attention to a preferred stimulus of a column enhances neuronal responses of layers 2/3 and 5, the output stations of cortical microcircuits, whereas attention suppresses neuronal responses of layer 4, the input station of cortical microcircuits. We demonstrate that the specific modulation pattern of layer-4 activity, which emerges from inter-laminar synaptic connections, is crucial for a rapid shift of attention to a currently unattended stimulus. Our results suggest that top-down signals act differently on different layers of the cortical microcircuit. © 2011 Wagatsuma, Potjans, Diesmann and Fukai.

关键词： Computation theory

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Continuous-wave photoinduced absorption studies in polythiophene and fullerene blended thin films

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Physical Review B 2011年第3期83卷 035305-035305页

作者： Takashi Kobayashi Keita Kinoshita Takashi Nagase Hiroyoshi Naito Department of Physics and Electronics Osaka Prefecture University 1-1 Gakuencho Sakai Osaka 599-8531 Japan The Research Institute for Molecular Electronic Devices Osaka Prefecture University 1-1 Gakuencho Sakai Osaka 599-8531 Japan Core Research for Evolutional Science and Technology (CREST) Japan Science and Technology Agency (JST) Japan

The generation and recombination dynamics of photocarriers (polarons) in poly(3-hexylthiophene) and [6,6]-phenyl-C61-butyric acid methyl ester blended thin films have been investigated by means of continuous-wave photoinduced absorption spectroscopy. Continuous-wave photoinduced absorption spectroscopy has the advantage of being used to investigate long-lived excited species with lifetimes that range from microseconds to milliseconds. In this time range, three kinds of excited species are recognized in the blends: trapped, mobile, and delocalized polarons. From the modulation-frequency dependence, the mean lifetimes of the three types of polarons at low temperature were estimated. It is known that polarons are not generated directly by the pump beam but rather through Coulombically bound radical pairs. We have found that this two-step model for polaron generation can be recognized on a microsecond time scale by continuous-wave photoinduced absorption measurements.

关键词： POLYTHIOPHENES FULLERENES THIN films POLARONS BUTYRIC acid

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Functional neuroimaging by using an implantable CMOS multimodal device in a freely-moving mouse

Functional neuroimaging by using an implantable CMOS multimo...

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IEEE Biomedical Circuits and Systems (BIOCAS)

作者： Takuma Kobayashi Hideki Tamura Yumiko Hatanaka Mayumi Motoyama Toshihiko Noda Kiyotaka Sasagawa Takashi Tokuda Yasuyuki Ishikawa Sadao Shiosaka Jun Ohta Core Research for Evolutional Science and Technology Japan Science and Technology Agency Kawaguchi Saitama Japan Graduate School of Materials Science Nara Institute of Science and Technology Ikoma Nara Japan Graduate School of Biological Sciences Nara Institute of Science and Technology Ikoma Nara Japan Division of Cerebral Circuitry National Institute for Physiological Sciences Okazaki Aichi Japan

We have developed implantable complementary metal oxide semiconductor (CMOS) multimodal devices to observe various neural activities in the brain. The devices, biomedical photonic large scale integration (BpLSI), have an image sensing array, light emitting diodes (LEDs), and an absorbing filter to enable a real-time fluorescence imaging. Additionally, BpLSI can equip with electrodes, a cannula, and an optical fiber for various applications. Here, we report three applications of BpLSI for freely-moving mice to visualize serine-protease activities in the hippocampus, to monitor kinetic alterations of dopaminergic-fibers in the striatum, and to obtain physiological responses with broad scope in the visual cortex.

关键词： Mice Fluorescence Imaging Neurons Visualization Hippocampus Biomedical monitoring

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Beamlike polarization entangled photon pairs generation by 2x2 fiber

Beamlike polarization entangled photon pairs generation by 2...

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High Intensity Lasers and High Field Phenomena, HILAS 2011

作者： Lo, Hsin-Pin Yabushita, Atsushi Luo, Chih-Wei Chen, Pochung Kobayashi, Takayoshi Department of Physics National Tsing Hua University Hsinchu 300 Taiwan Department of Electrophysics National Chiao-Tung University Hsinchu 300 Taiwan Core Research for Evolutional Science and Technology Japan Science and Technology Agency 4-1-8 Honcho Kawaguchi Saitama 332-0012 Japan University of Electro-Communications 1-5-1 Chofugaoka Chofu Tokyo 182-8585 Japan Institute of Laser Engineering Osaka University 2-6 Yamada oka Suita Osaka 565-0971 Japan

Beamlike photon pairs generated by pumping the Type-II BBO crystal. Then inserting into the 2x2 fiber, the polarization entangled photon pairs be measured from the output. © 2011 Optical Society of America.

ISBN: (纸本)9781557529046

关键词： Polarization

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Ultrafast Time-Resolved Spectroscopy of PYP by a Sub-8fs Pulse at 400 nm

Ultrafast Time-Resolved Spectroscopy of PYP by a Sub-8fs Pul...

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第三届亚洲光谱会议

作者： J.Liu A.Yabushita S.Taniguchi T.Kobayashi State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of Sciences Advanced Ultrafast Laser Research Center University of Electro-Communications Core Research for Evolutional Science and Technology (CREST) Japan Science and Technology Agency Department of Electrophysics Chiao Tung University Institute for Laser Technology Osaka University

Ultrafast time-resolved PYP was studied by pump-probe spectroscopy using a sub-8 fs pulse laser with a central wavelength at 400 nm[1].The broadband spectrum of the UV pulse allowed us to detect the pump-probe signal over a broad spectral range in UV covering 360-440nm.A 128-channel detector array was used to simultaneously obtain the

关键词： PYP Ultrafast Time-Resolved Spectroscopy of PYP by a Sub-8fs Pulse at 400 nm

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