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Subgrouping of Burkitt lymphoma variants by DNA methylation is driven by an EBV-associated epigenotype

Hematological Oncology 2023年第S2期41卷

作者： S. Glaser C. Del Val R. Wagener H. Kretzmer W. Klapper M. Hummel O. Ammerpohl P. Lichter B. Burkhardt L. Trümper S. Mbulaiteye Institute of Human Genetics Ulm University and Ulm University Medical Center Ulm Germany Department of Computer Science and Artifical Intelligence Andalusian Research Institute in Data Science and Computational Intelligence (DaSCI) Universtiy of Granada Granada Spain Transciptome Bioinformatics Group LIFE Research Center for Civilization Diseases University of Leipzig Leipzig Germany Department of Pathology University of Kiel/University Hospital Schleswig-Holstein Kiel Germany Institute of Pathology Charité – University Medicine Berlin Berlin Germany Division of Molecular Genetics German Cancer Research Center Heidelberg Germany Department of Pediatric Hematology and Oncology University Hospital Münster Münster Germany Hematology and Oncology University of Göttingen Göttingen Germany Division of Cancer Epidemiology and Genetics National Cancer Institute National Institutes of Health Bethesda MC USA

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The multichord stellar occultation by the centaur Bienor on

arXiv

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arXiv 2022年

作者： Fernández-Valenzuela, Estela Morales, N. Vara-Lubiano, M. Ortiz, J.L. Benedetti-Rossi, G. Sicardy, B. Kretlow, M. Santos-Sanz, P. Morgado, B. Souami, D. Organero, F. Ana, L. Fonseca, F. Román, A. Alonso, S. Gonçalves, R. Ferreira, M. Iglesias-Marzoa, R. Lamadrid, J.L. Alvarez-Candal, A. Assafin, M. Braga-Ribas, F. Camargo, J.I.B. Colas, F. Desmars, J. Duffard, R. Lecacheux, J. Gomes-Júnior, A.R. Rommel, F.L. Vieira-Martins, R. Pereira, C.L. Casanova, V. Selva, A. Perelló, C. Mottola, S. Hellmich, S. Maestre, J.L. Castro-Tirado, A.J. Pal, A. Trigo-Rodriguez, J.M. Beisker, W. Laporta, A. Garcés, M. Escaned, L. Bretton, M. Florida Space Institute UCF 12354 Research Parkway Partnership 1 building Room 211 Orlando United States Instituto de astrofísica de Andalucía CSIC Glorieta de la Astronomía s/n Granada18008 Spain UNESP - São Paulo State University Grupo de Dinâmica Orbital e Planetologia SP Guaratinguetá12516-410 Brazil Laboratório Interinstitucional de e-Astronomia - LIneA INCT do e-Universo Rua Gal. José Cristino 77 RJ Rio de Janeiro20921-400 Brazil LESIA Observatoire de Paris Université PSL Sorbonne Université Université de Paris CNRS Meudon92190 France naXys University of Namur 8 Rempart de la Vierge NamurB-5000 Belgium Rua Gal. José Cristino 77—Bairro Imperial de São Cristóvão Rio de Janeiro20921-400 Brazil Complejo Astronómico de La Hita Camino de Doña Sol s/n LaVilla de Don fadrique45850 Spain Sociedad Astronómica Granadina Apartado de Correos 195 Granada18080 Spain Software Engineering Department Andalusian Research Institute in Data Science and Computational Intelligence University of Granada Spain Instituto Politécnico de Tomar CI2 e U.D. Matemática e Física Tomar2300-313 Portugal Centro Ciência Viva Alto de Santa Bárbara Via Galileu Galilei 817 Constância2250-100 Portugal Centro de Estudios de Física del Cosmos de Aragón Plaza San Juan 1 Teruel44001 Spain Instituto de Física Aplicada a las Ciencias y las Tecnologías Universidad de Alicante San Vicent del Raspeig AlicanteE03080 Spain Observatório do Valongo/UFRJ Ladeira Pedro Antonio 43 RJ Rio de Janeiro20.080-090 Brazil Av. Sete de Setembro 3165 CEP Curitiba80230-901 Brazil Institut Polytechnique des Sciences Avancées IPSA 63 boulevard de Brandebourg Ivry-sur-SeineF-94200 France Institut de Mécanique Céleste et de Calcul des Éphémérides IMCCE Observatoire de Paris PSL Research University CNRS Sorbonne Universités UPMC Univ Paris 06 Univ. Lille 77 Av. Denfert-Rochereau ParisF-75014 France Agrupación Astronómica de Sabadell Carrer Prat de la Riba 116 Sabadell08206 Spai

Within our program of physical characterization of trans-Neptunian objects and centaurs, we predicted a stellar occultation by the centaur (54598) Bienor to occur on January 11, 2019, with good observability potential. We obtained high accuracy astrometric data to refine the prediction, resulting in a shadow path favorable for the Iberian Peninsula. This encouraged us to carry out an occultation observation campaign that resulted in five positive detections from four observing sites. This is the fourth centaur for which a multichord (more than two chords) stellar occultation has been observed so far, the other three being (2060) Chiron, (10199) Chariklo, and (95626) 2002 GZ32. From the analysis of the occultation chords, combined with the rotational light curve obtained shortly after the occultation, we determined that Bienor has an area-equivalent diameter of 150 ± 20 km. This diameter is ∼ 30 km smaller than the one obtained from thermal measurements. The position angle of the short axis of the best fitting ellipse obtained through the analysis of the stellar occultation does not match that of the spin axis derived from long-term photometric models. We also detected a strong irregularity in one of the minima of the rotational light curve that is present no matter the aspect angle at which the observations were done. We present different scenarios to reconcile the results from the different techniques. We did not detect secondary drops related to potential rings or satellites. Nonetheless, similar rings in size to that of Chariklo’s cannot be discarded due to low data accuracy. © 2022, CC BY.

关键词： Photometry

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