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arXiv 2024年

作者： Wilkinson, Sean R. Aloqalaa, Meznah Belhajjame, Khalid Crusoe, Michael R. de Paula Kinoshita, Bruno Gadelha, Luiz Garijo, Daniel Ragnar Gustafsson, Ove Johan Juty, Nick Kanwal, Sehrish Khan, Farah Zaib Köster, Johannes Gehlen, Karsten Petersvon Pouchard, Line Rannow, Randy K. Soiland-Reyes, Stian Soranzo, Nicola Sufi, Shoaib Sun, Ziheng Vilne, Baiba Wouters, Merridee A. Yuen, Denis Goble, Carole Oak Ridge Leadership Computing Facility Oak Ridge National Laboratory Oak RidgeTN United States Department of Computer Science University of Manchester Manchester United Kingdom LAMSADE PSL Paris Dauphine University Paris France Berlin Germany Earth Sciences Barcelona Supercomputing Center Barcelona Spain Heidelberg Germany Ontology Engineering Group Universidad Politécnica de Madrid Madrid Spain Australian BioCommons University of Melbourne MelbourneVIC Australia ParkvilleVIC Australia University Medicine Essen University of Duisburg-Essen Essen Germany Data Management Department Deutsches Klimarechenzentrum GmbH Hamburg Germany Center for Computing Research Sandia National Laboratories AlbuquerqueNM United States Silverdraft Supercomputing BoiseID United States Informatics Institute University of Amsterdam Amsterdam Netherlands Earlham Institute Norwich United Kingdom Center for Spatial Information Science and Systems Department of Geography and Geoinformation Science George Mason University FairfaxVA United States Bioinformatics Group Riga Stradins University Riga Latvia School of Clinical Medicine University of New South Wales KensingtonNSW Australia Ontario Institute for Cancer Research TorontoON Canada

Recent trends within computational and data sciences show an increasing recognition and adoption of computational workflows as tools for productivity and reproducibility that also democratize access to platforms and processing know-how. As digital objects to be shared, discovered, and reused, computational workflows benefit from the FAIR principles, which stand for Findable, Accessible, Interoperable, and Reusable. The Workflows Community Initiative’s FAIR Workflows Working group (WCI-FW), a global and open community of researchers and developers working with computational workflows across disciplines and domains, has systematically addressed the application of both FAIR data and software principles to computational workflows. We present recommendations with commentary that reflects our discussions and justifies our choices and adaptations. These are offered to workflow users and authors, workflow management system developers, and providers of workflow services as guidelines for adoption and fodder for discussion. The FAIR recommendations for workflows that we propose in this paper will maximize their value as research assets and facilitate their adoption by the wider community. © 2024, CC BY.

关键词： Application programs

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Liver Segmentation in Time-resolved C-arm CT Volumes Reconstructed from Dynamic Perfusion Scans using Time Separation Technique

Liver Segmentation in Time-resolved C-arm CT Volumes Reconst...

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International Image Processing, Applications and Systems Conference (IPAS)

作者： Soumick Chatterjee Hana Haseljić Robert Frysch Vojtěch Kulvait Vladimir Semshchikov Bennet Hensen Frank Wacker Inga Brüsch Thomas Werncke Oliver Speck Andreas Nürnberger Georg Rose Data and Knowledge Engineering Group Faculty of Computer Science Otto von Guericke University Magdeburg Magdeburg Germany Department of Biomedical Magnetic Resonance Faculty of Nature Science Otto von Guericke University Magdeburg Magdeburg Germany Faculty of Electrical Engineering and Information Technology Institute for Medical Engineering Otto von Guericke University Magdeburg Magdeburg Germany Faculty of Electrical Engineering and Information Technology Research Campus STIMULATE Otto von Guericke University Magdeburg Magdeburg Germany Institute of Materials Physics Helmholtz-Zentrum hereon Geesthacht Germany Institute of Diagnostic and Interventional Radiology Hannover Medical School Hannover Germany Research Campus STIMULATE Otto von Guericke University Magdeburg Magdeburg Germany Institute for Laboratory Animal Science Hannover Medical School Hannover Germany Department of Biomedical Magnetic Resonance Faculty of Nature Science Otto von Guericke University Magdeburg German Center for Neurodegenerative Disease Magdeburg Germany Center for Behavioral Brain Sciences Magdeburg Germany

ISBN: (纸本)9781665462204

Perfusion imaging is a valuable tool for diagnosing and treatment planning for liver tumours. The time separation technique (TST) has been successfully used for modelling C-arm cone-beam computed tomography (CBCT) perfusion data. The reconstruction can be accompanied by the segmentation of the liver - for better visualisation and for generating comprehensive perfusion maps. Recently introduced Turbolift learning has been seen to perform well while working with TST reconstructions, but has not been explored for the time-resolved volumes (TRV) estimated out of TST reconstructions. The segmentation of the TRVs can be useful for tracking the movement of the liver over time. This research explores this possibility by training the multi-scale attention UNet of Turbolift learning at its third stage on the TRVs and shows the robustness of Turbolift learning since it can even work efficiently with the TRVs, resulting in a Dice score of $0.864\pm 0.004$ .

关键词： Training Image segmentation Computed tomography Computational modeling Motion segmentation Liver Imaging

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ShuffleUNet: Super resolution of diffusion-weighted MRIs using deep learning

arXiv

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arXiv 2021年

作者： Chatterjee, Soumick Sciarra, Alessandro Dünnwald, Max Mushunuri, Raghava Vinaykanth Podishetti, Ranadheer Rao, Rajatha Nagaraja Gopinath, Geetha Doddapaneni Oeltze-Jafra, Steffen Speck, Oliver Nürnberger, Andreas Data and Knowledge Engineering Group Otto von Guericke University Magdeburg Germany Faculty of Computer Science Otto von Guericke University Magdeburg Germany Department of Biomedical Magnetic Resonance Otto von Guericke University Magdeburg Germany MedDigit Department of Neurology Medical Faculty University Hospital Magdeburg Germany German Centre for Neurodegenerative Diseases Magdeburg Germany Center for Behavioral Brain Sciences Magdeburg Germany Leibniz Institute for Neurobiology Magdeburg Germany

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance Imaging (MRI) in high spatial resolution would play an important role in visualising such fibre tracts in a superior manner. However, obtaining an image of such resolution comes at the expense of longer scan time. Longer scan time can be associated with the increase of motion artefacts, due to the patient’s psychological and physical conditions. Single Image Super-Resolution (SISR), a technique aimed to obtain high-resolution (HR) details from one single low-resolution (LR) input image, achieved with Deep Learning, is the focus of this study. Compared to interpolation techniques or sparse-coding algorithms, deep learning extracts prior knowledge from big datasets and produces superior MRI images from the low-resolution counterparts. In this research, a deep learning based super-resolution technique is proposed and has been applied for DW-MRI. Images from the IXI dataset have been used as the ground-truth and were artificially downsampled to simulate the low-resolution images. The proposed method has shown statistically significant improvement over the baselines and achieved an SSIM of 0.913 ± 0.045. Copyright © 2021, The Authors. All rights reserved.

关键词： Magnetic resonance imaging

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Assessing Trustworthy AI in Times of COVID-19: Deep Learning for Predicting a Multiregional Score Conveying the Degree of Lung Compromise in COVID-19 Patients

IEEE Transactions on Technology and Society

引用

IEEE Transactions on Technology and Society 2022年第4期3卷 272-289页

作者： Allahabadi, Himanshi Amann, Julia Balot, Isabelle Beretta, Andrea Binkley, Charles Bozenhard, Jonas Bruneault, Frederick Brusseau, James Candemir, Sema Cappellini, Luca Alessandro Chakraborty, Subrata Cherciu, Nicoleta Cociancig, Christina Coffee, Megan Ek, Irene Espinosa-Leal, Leonardo Farina, Davide Fieux-Castagnet, Genevieve Frauenfelder, Thomas Gallucci, Alessio Giuliani, Guya Golda, Adam Van Halem, Irmhild Hildt, Elisabeth Holm, Sune Kararigas, Georgios Krier, Sebastien A. Kuhne, Ulrich Lizzi, Francesca Madai, Vince I. Markus, Aniek F. Masis, Serg Mathez, Emilie Wiinblad Mureddu, Francesco Neri, Emanuele Osika, Walter Ozols, Matiss Panigutti, Cecilia Parent, Brendan Pratesi, Francesca Moreno-Sanchez, Pedro A. Sartor, Giovanni Savardi, Mattia Signoroni, Alberto Sormunen, Hanna-Maria Spezzatti, Andy Srivastava, Adarsh Stephansen, Annette F. Theng, Lau Bee Tithi, Jesmin Jahan Tuominen, Jarno Umbrello, Steven Vaccher, Filippo Vetter, Dennis Westerlund, Magnus Wurth, Renee Zicari, Roberto V. Ey Netherlands Enterprise Intelligence Department Amsterdam1083 HP Netherlands Eth Zurich Health Ethics and Policy Lab Department of Health Sciences and Technology Zürich8092 Switzerland Center for Diplomatic and Strategic Studies Postgraduate Studies in Diplomacy and International Relations Paris75015 France Pisa56124 Italy Hackensack Meridian Health Bioethics Center EdisonNJ08820 United States University of Oxford Faculty of Philosophy OxfordOX2 6GG United Kingdom Collège André- Laurendeau Philosophie Department MontrealQCH8N 2J4 Canada Université du Québec À Montréal École des Médias MontrealQCH2L 2C4 Canada Pace University Philosophy Department New YorkNY10038 United States The Ohio State University Wexner Medical Center Department of Radiology ColumbusOH43210 United States Humanitas Research Hospital Department of Radiology Milan20089 Italy Humanitas University Department of Biomedical Sciences Milan20089 Italy University of New England Faculty of Science Agriculture Business and Law ArmidaleNSW2351 Australia University of Technology Sydney Faculty of Engineering and Information Technology SydneyNSW2007 Australia Scuola Superiore Sant'Anna European Centre of Excellence on the Regulation of Robotics and Ai Pisa56127 Italy University of Bremen Group of Computer Architecture Bremen28359 Germany New York University Grossman School of Medicine Division of Infectious Diseases and Immunology Department of Medicine New YorkNY10016 United States Digital Institute Ai Research Section Stockholm16731 Sweden Arcada University of Applied Sciences Department of Business Management and Analytics Helsinki00550 Finland University of Brescia Radiological Sciences and Public Health Department of Medical and Surgical Specialties Brescia25121 Italy Sncf Reseau Sa Ethique Groupe La Plaine93418 France Institute of Diagnostic and Interventional Radiology University Hospital Zurich Zürich8091 Switzerland Eindhoven University of Tech

This article's main contributions are twofold: 1) to demonstrate how to apply the general European Union's High-Level Expert group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does 'trustworthy AI' mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays. It has been experimentally deployed in the radiology department of the ASST Spedali Civili clinic in Brescia, Italy, since December 2020 during pandemic time. The methodology we have applied for our post-hoc assessment, called Z-Inspection®, uses sociotechnical scenarios to identify ethical, technical, and domain-specific issues in the use of the AI system in the context of the pandemic. © 2020 IEEE.

关键词： COVID-19

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A Markov Traffic Model for Signalized Traffic Networks Based on Bayesian Estimation

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IFAC-PapersOnLine 2020年第2期53卷 15029-15034页

作者： S.Y. Liu S. Lin Y.B. Wang B. De Schutter W.H.K. Lam School of Computer Science and Technology University of Chinese Academy of Sciences Beijing 100089 China Key Lab of Big Data Mining and Knowledge Management Chinese Academy of Sciences College of Civil Engineering and Architecture Zhejiang University PR China Delft Center for Systems and Control Delft University of Technology The Netherlands Department of Civil and Structural Engineering The Hong Kong Polytechnic University Hong Kong SAR China

In order to better understand the stochastic dynamic features of signalized traffic networks, we propose a Markov traffic model to simulate the dynamics of traffic link flow density for signalized urban traffic networks with demand uncertainty. In this model, we have four different state modes for the link according to different congestion levels of the link. Each link can only be in one of the four link state modes at any time, and the transition probability from one state to the other state is estimated by Bayesian estimation based on the distributions of the dynamic traffic flow densities, and the posterior probabilities. Therefore, we use a first-order Markov Chain Model to describe the dynamics of the traffic flow evolution process. We illustrate our approach for a small traffic network. Compared with the data from the microscopic traffic simulator SUMO, the proposed model can estimate the link traffic densities accurately and can give a reliable estimation of the uncertainties in the dynamic process of signalized traffic networks.

关键词： Markov traffic model Traffic signals Bayesian Urban traffic network

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Structural Modelling, Design Automation, and a Generalized Routing Technique for Digital Microfluidic Biochips with Hexagonal Electrodes

Structural Modelling, Design Automation, and a Generalized R...

引用

IEEE Region 10 Symposium

作者： Amartya Dutta Riya Majumder Debasis Dhal Rajat Kumar Pal Department of Computer Science and Engineering B. P. Poddar Institute of Management and Technology Kolkata India Department of Computer Science and Engineering Supreme Knowledge Foundation Group of Institutions West Bengal India Department of Computer Science and Engineering University of Calcutta Kolkata India

Digital microfluidic biochips skilfully manoeuvre a significant assignment in the realm of biochips by supervising droplets of nano-or micro-litre volume. Enhancement of reliable and precise outcomes of digital microfluidic biochips open a new era in environmental as well as biological science. Being concerned about various advancements and considering all design specifications along with the decisive factors like fluidic and pin constraints, we have structured the hexagonal electrode based digital microfluidic biochip system over traditional square electrodes, and also implemented the most significant modular operation, i.e. droplet routing regarding its behavioural natures. Finally, we have devised an improved safe droplet routing algorithm on the hexagonal cell array without any droplet interference and incorporated a comparative study between this new architecture and the existing square one.

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Retrospective motion correction of MR images using prior-assisted deep learning

arXiv

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arXiv 2020年

作者： Chatterjee, Soumick Sciarra, Alessandro Dünnwald, Max Oeltze-Jafra, Steffen Nürnberger, Andreas Speck, Oliver Department of Biomedical Magnetic Resonance Data and Knowledge Engineering Group Faculty of Computer Science Otto-von-Guericke Univeristy Magdeburg Germany MedDigit Department of Neurology Medical Faculty University Hopspital Department of Biomedical Magnetic Resonance Otto-von-Guericke Univeristy Magdeburg Germany MedDigit Department of Neurology Medical Faculty University Hopspital Faculty of Computer Science Otto-von-Guericke Univeristy Magdeburg Germany MedDigit Department of Neurology Medical Faculty University Hopspital German Centre for Neurodegenerative Diseases Center for Behavioral Brain Sciences Magdeburg Germany Data and Knowledge Engineering Group Faculty of Computer Science Otto-von-Guericke Univeristy Center for Behavioral Brain Sciences Magdeburg Germany Department of Biomedical Magnetic Resonance Otto-von-Guericke Univeristy German Centre for Neurodegenerative Diseases Leibniz Institute for Neurobiology Center for Behavioral Brain Sciences Magdeburg Germany

In MRI, motion artefacts are among the most common types of artefacts. They can degrade images and render them unusable for accurate diagnosis. Traditional methods, such as prospective or retrospective motion correction, have been proposed to avoid or alleviate motion artefacts. Recently, several other methods based on deep learning approaches have been proposed to solve this problem. This work proposes to enhance the performance of existing deep learning models by the inclusion of additional information present as image priors. The proposed approach has shown promising results and will be further investigated for clinical validity. Copyright © 2020, The Authors. All rights reserved.

关键词： Magnetic resonance imaging

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Traffic Optimization Algorithms in Optical Networks For Real Time Traffic Analysis

引用

Optik 2022年

作者： Suresh Kumar. K Swati Vijay Shinde S. Venkata Lakshmi R.S. Sabeenian Koppisetti Durga Bhavani K.V.S.R. Murthy Department of Information Technology Saveetha Engineering College Tamil Nadu India Department of Computer Engineering Pimpri Chinchwad College of Engineering Pune India Dept. of Artificial Intelligence and Data Science Sri Krishna College of Engineering and Technology Coimbatore India Department of ECE Sona College of Technology Salem Department of Management Studies Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences Chennai India EEE Department & Dean (R&D) Aditya Group of Engineering Colleges

The rapid growth of metropolitan areas poses significant traffic control issues. Advanced telecommunication structures, such as the IoT (Internet of Things) technology, including wireless connections, produce enormous amounts of diverse traffic information. Conventional networking control approaches for tracking and information analysis confront certain obstacles and problems in specific systems, like reliability and efficient actual-time analysis of massive datasets. Furthermore, due to variables like gadget portability and connection diversity, the overall structure of internet activity, particularly in wireless networks, exhibits extremely complicated activity. The article aims to create a method for collecting high-quality, comprehensive information like transportation flowing strength, travel routes, and mean vehicle velocity. Simultaneously, information is gathered throughout the whole operational zone of junctions and neighboring highway segments under the city video security sensor perspective. More profound learning methods will be used within the communication domain for Networking Transport management and Analytics (NTMA) activities such as traffic categorization and forecasting. The YOLOv3 artificial routing topology, as well as a SORT-accessible monitor, are used in our approach. Utilizing extended masking branches and improving its geometry of anchoring, overall essential efficiency in YOLO has been enhanced. We employed a technique of viewpoint conversion using parameters from actual pictures to global dimensions for computing overall vehicular velocities.

关键词： Networking Traffic management and Analytics (NTMA) real-time surveillance traffic management and database processing

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Why is the Winner the Best?

Why is the Winner the Best?

引用

Conference on computer Vision and Pattern Recognition (CVPR)

作者： M. Eisenmann A. Reinke V. Weru M. D. Tizabi F. Isensee T. J. Adler S. Ali V. Andrearczyk M. Aubreville U. Baid S. Bakas N. Balu S. Bano J. Bernal S. Bodenstedt A. Casella V. Cheplygina M. Daum M. De Bruijne A. Depeursinge R. Dorent J. Egger D. G. Ellis S. Engelhardt M. Ganz N. Ghatwary G. Girard P. Godau A. Gupta L. Hansen K. Harada M. Heinrich N. Heller A. Hering A. Huaulmé P. Jannin A. E. Kavur O. Kodym M. Kozubek J. Li H. Li J. Ma C. Martín-Isla B. Menze A. Noble V. Oreiller N. Padoy S. Pati K. Payette T. Rädsch J. Rafael-Patiño V. Singh Bawa S. Speidel C. H. Sudre K. Van Wijnen M. Wagner D. Wei A. Yamlahi M. H. Yap C. Yuan M. Zenk A. Zia D. Zimmerer D. Aydogan B. Bhattarai L. Bloch R. Brüngel J. Cho C. Choi Q. Dou I. Ezhov C. M. Friedrich C. Fuller R. R. Gaire A. Galdran Á. García Faura M. Grammatikopoulou S. Hong M. Jahanifar I. Jang A. Kadkhodamohammadi I. Kang F. Kofler S. Kondo H. Kuijf M. Li M. Luu T. Martinčič P. Morais M. A. Naser B. Oliveira D. Owen S. Pang J. Park S. Park S. Płotka E. Puybareau N. Rajpoot K. Ryu N. Saeed A. Shephard P. Shi D. Štepec R. Subedi G. Tochon H. R. Torres H. Urien J. L. Vilaça K. A. Wahid H. Wang J. Wang L. Wang X. Wang B. Wiestler M. Wodzinski F. Xia J. Xie Z. Xiong S. Yang Y. Yang Z. Zhao K. Maier-Hein P. F. Jäger A. Kopp-Schneider L. Maier-Hein Division of Intelligent Medical Systems German Cancer Research Center (DKFZ) Heidelberg Germany Helmholtz Imaging German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Mathematics and Computer Science Heidelberg University Heidelberg Germany Division of Biostatistics German Cancer Research Center (DKFZ) Heidelberg Germany Division of Medical Image Computing German Cancer Research Center (DKFZ) Heidelberg Germany Faculty of Engineering and Physical Sciences School of Computing University of Leeds Leeds UK Institute of Informatics School of Management HES-SO Valais-Wallis University of Applied Sciences and Arts Western Switzerland Sierre Switzerland Department of Nuclear Medicine and Molecular Imaging Lausanne University Hospital Lausanne Switzerland Technische Hochschule Ingolstadt Ingolstadt Germany Center for Artificial Intelligence and Data Science for Integrated Diagnostics (AI2D) and Center for Biomedical Image Computing and Analytics (CBICA) University of Pennsylvania Philadelphia PA USA Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology Perelman School of Medicine University of Pennsylvania Philadelphia PA USA Department of Radiology University of Washington Seattle WA USA Department of Computer Science Wellcome/EPSRC Centre for Interventional and Surgical Sciences (WEISS) University College London London UK Universitat Autònoma de Barcelona & Computer Vision Center Barcelona Spain Division of Translational Surgical Oncology National Center for Tumor Diseases (NCT/UCC) Dresden Dresden Germany Department of Advanced Robotics Istituto Italiano di Tecnologia Italy Department of Electronics Information and Bioengineering Politecnico di Milano Milan Italy IT University of Copenhagen Copenhagen Denmark Department of General Visceral and Transplantation Surgery Heidelberg University Hospital Heidelberg Germany Department of Radiology and Nuc

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multicenter study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and post-processing (66%). The “typical” lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

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The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels (vol 400, pg 1619, 2022)

引用

LANCET 2022年第10365期400卷 1766-1766页

作者： Romanello, M. Di Napoli, C. Drummond, P. Institute for Global Health University College London London UK School of Agriculture Policy and Development University of Reading Reading UK Institute for Sustainable Resources University College London London UK Department of Global Health Centre for Health and the Global Environment University of Washington Seattle WA USA UCL Energy Institute University College London London UK Department of Health Sciences University of York York UK Department of Meteorology University of Reading Reading UK Institute for Risk and Disaster Reduction University College London London UK School of Earth and Environment University of Leeds Leeds UK Centre on Climate Change and Planetary Health London School of Hygiene & Tropical Medicine London UK School of Population Health University of Melbourne Melbourne VIC Australia Department of Earth System Science Tsinghua University Beijing China Mercator Research Institute on Global Commons and Climate Change Berlin Germany Department of Environment Climate Change and Health World Health Organization Geneva Switzerland Institute of Environmental Sciences University of Geneva Geneva Switzerland Cardiovascular Epidemiology Unit Department of Public Health & Primary Care University of Cambridge Cambridge UK School of Government University of Birmingham Birmingham UK Economic Analysis of Climate Impacts and Policy Division Centro Euro-Mediterraneo sui Cambiamenti Climatici Venice Italy Institute for Environmental Design and Engineering University College London London UK Natural Resources Institute University of Greenwich London UK Department of Environmental Health Sciences and Yale Center on Climate Change and Health Yale University New Haven CT USA Department of Civil and Environmental Engineering Northeastern University Boston MA USA Department of Fish and Wildlife Conservation Virginia Polytechnic Institute and State University Blacksburg VA USA Department of Geography University College London London UK NU

With advancements in the science of detection and attribution studies, the influence of climate change over many events has now been quantified. Because of the rapidly increasing temperatures, vulnerable populations (adults older than 65 years, and children younger than one year of age) were exposed to 3·7 billion more heatwave days in 2021 than annually in 1986–2005 (indicator 1.1.2), and heat-related deaths increased by 68% between 2000–04 and 2017–21 (indicator 1.1.5), a death toll that was significantly exacerbated by the confluence of the COVID-19 pandemic. Despite the local cooling and overall health benefits of urban greenspaces, only 277 (27%) of 1038 global urban centres were at least moderately green in 2021 (indicator 2.2.3), and the number of households with air conditioning increased by 66% from 2000 to 2020, a maladaptive response that worsens the energy crisis and further increases urban heat, air pollution, and greenhouse gas emissions. [...]millions of people do not have access to the energy needed to keep their homes at healthy temperatures, preserve food and medication, and meet the seventh Sustainable Development Goal (to ensure access to affordable, reliable, sustainable, and modern energy for all). Aggravating this situation even further, governments continue to incentivise fossil fuel production and consumption: 69 (80%) of 86 countries reviewed had net-negative carbon prices (ie, provided a net subsidy to fossil fuels) for a net total of US$400 billion

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