In chemoinformatics and medicinal chemistry, machine learning has evolved into an important approach. In recent years, increasing computational resources and new deep learning algorithms have put machine learning onto...
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In chemoinformatics and medicinal chemistry, machine learning has evolved into an important approach. In recent years, increasing computational resources and new deep learning algorithms have put machine learning onto a new level, addressing previously unmet challenges in pharmaceutical research. In silico approaches for compound activity predictions, de novo design, and reaction modeling have been further advanced by new algorithmic developments and the emergence of bigdata in the field. Herein, novel applications of machine learning and deep learning in chemoinformatics and medicinal chemistry are reviewed. Opportunities and challenges for new methods and applications are discussed, placing emphasis on proper baseline comparisons, robust validation methodologies, and new applicability domains.
This book constitutes the refereed proceedings of the 17th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2022, held in Salamanca, Spain, in September 2022.;The 43 full papers presented in thi...
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ISBN:
(数字)9783031154713
ISBN:
(纸本)9783031154706
This book constitutes the refereed proceedings of the 17th International Conference on Hybrid Artificial Intelligent Systems, HAIS 2022, held in Salamanca, Spain, in September 2022.;The 43 full papers presented in this book were carefully reviewed and selected from 67 submissions. They were organized in topical sections as follows: bioinformatics; data mining and decision support systems; deep learning; evolutionary computation; HAIS applications; image and speech signal processing; and optimization techniques.
The rise of social media has led to vast amounts of user-generated content, with emotions ranging from joy to anger. Negative comments often target individuals, communities, or brands, prompting successful efforts to ...
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The rise of social media has led to vast amounts of user-generated content, with emotions ranging from joy to anger. Negative comments often target individuals, communities, or brands, prompting successful efforts to detect harmful speech such as hate speech, cyberbullying, and abuse. Recently, another type of speech referred to as ‘Hope Speech’ has gained attention from the research community. Hope speech consists of positive affirmations or words of reassurance, encouragement, consolation or motivation offered to the affected individual/ community during the lean periods of life. However, there has been relatively less research focused on the detection of hope speech, more particularly in low-resource languages. This paper, therefore, attempts to develop an ensemble model for detecting hope speech in some low-resource languages. data for four different languages, namely English, Kannada, Malayalam and Tamil are obtained and experimented with different deep learning-based models. An ensemble model is proposed to combine the advantages of the better performing models. Experimental results demonstrate the superior performance of the proposed Ensemble (LSTM, mBERT, XLM-RoBERTa) model compared to individual models based on data from all four languages (weighted average F1-score for English is 0.93; for Kannada is 0.74; for Malayalam is 0.82; and for Tamil is 0.60). Thus, the proposed ensemble model proves to be a suitable approach for hope speech detection in the given low resource languages.
Distributed Collaborative Machine Learning (DCML) has emerged in artificial intelligence-empowered edge computing environments, such as the Industrial Internet of Things (IIoT), to process tremendous data generated by...
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Distributed Collaborative Machine Learning (DCML) has emerged in artificial intelligence-empowered edge computing environments, such as the Industrial Internet of Things (IIoT), to process tremendous data generated by smart devices. However, parallel DCML frameworks require resource-constrained devices to update the entire Deep Neural Network (DNN) models and are vulnerable to reconstruction attacks. Concurrently, the serial DCML frameworks suffer from training efficiency problems due to their serial training nature. In this paper, we propose a Model Pruning-enabled Federated Split Learning framework (MP-FSL) to reduce resource consumption with a secure and efficient training scheme. Specifically, MP-FSL compresses DNN models by adaptive channel pruning and splits each compressed model into two parts that are assigned to the client and the server. Meanwhile, MP-FSL adopts a novel aggregation algorithm to aggregate the pruned heterogeneous models. We implement MP-FSL with a real FL platform to evaluate its performance. The experimental results show that MP-FSL outperforms the state-of-the-art frameworks in model accuracy by up to 1.35%, while concurrently reducing storage and computational resource consumption by up to 32.2% and 26.73%, respectively. These results demonstrate that MP-FSL is a comprehensive solution to the challenges faced by DCML, with superior performance in both reduced resource consumption and enhanced model performance.
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