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MILCOM, Military Communications Conference

作者： Sridhar Venkatesan Jason A. Youzwak Shridatt Sugrim Cho-Yu J. Chiang Alexander Poylisher Matthew Witkowski Gary Walther Michelle Wolberg Ritu Chadha E. Allison Newcomb Blaine Hoffman Norbou Buchler Machine Learning and Data Analytics Research Perspecta Labs Inc. Basking Ridge NJ USA Computational and Information Science Directorate U.S. CCDC Army Research Laboratory Aberdeen MD USA Human Research and Engineering Directorate U.S. CCDC Army Research Laboratory

ISBN: (数字)9781728142807

ISBN: (纸本)9781728142814

Cyber training, security testing, and research and development activities are vital to improve the security posture of a network. Currently, many institutions use cyber security testbeds to conduct these activities in an isolated virtual environment. One of the important requirements for such an environment is to provide organizers (or experimenters) with a library of vulnerable network scenarios and capabilities to mount attacks against them. However, the task of preparing a vulnerable network scenario in current testbed environments is costly in time and labor, requires significant support from the testbed staff. To this end, we present a toolset called VulnerVAN that creates a vulnerable network scenario to realize an attack sequence. In this paper, we discuss the design of VulnerVAn - our proof-of-concept implementation on CyberVAN - and present a new high-level attack specification language that enables users to chain attack steps into an attack sequence. For a given attack sequence and network scenario, VulnerVAN identifies all possible attack paths through the network that can realize the attack sequence, and provides instructions to configure machines on an attack path selected by the user. VulnerVAn also provides an attack blueprint that can guide a Red team or an automated attacker to execute the attack sequence. To demonstrate VulnerVAN's capability, we consider the use-case of a typical data exfiltration attack sequence conducted by APTs and study the performance of VulnerVAn in mapping the attack sequence to different networks.

关键词： data security Training Specification languages Virtual environments

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Strategic priorities for transformative progress in advancing biology with proteomics and artificial intelligence

arXiv

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arXiv 2025年

作者： Sun, Yingying Jun, A. Liu, Zhiwei Sun, Rui Qian, Liujia Payne, Samuel H. Bittremieux, Wout Ralser, Markus Li, Chen Chen, Yi Dong, Zhen Perez-Riverol, Yasset Khan, Asif Sander, Chris Aebersold, Ruedi Vizcaíno, Juan Antonio Krieger, Jonathan R. Yao, Jianhua Wen, Han Zhang, Linfeng Zhu, Yunping Xuan, Yue Sun, Benjamin Boyang Qiao, Liang Hermjakob, Henning Tang, Haixu Gao, Huanhuan Deng, Yamin Zhong, Qing Chang, Cheng Bandeira, Nuno Li, Ming Weinan, E. Sun, Siqi Yang, Yuedong Omenn, Gilbert S. Zhang, Yue Xu, Ping Fu, Yan Liu, Xiaowen Overall, Christopher M. Wang, Yu Deutsch, Eric W. Chen, Luonan Cox, Jürgen Demichev, Vadim He, Fuchu Huang, Jiaxing Jin, Huilin Liu, Chao Li, Nan Luan, Zhongzhi Song, Jiangning Yu, Kaicheng Wan, Wanggen Wang, Tai Zhang, Kang Zhang, Le Bell, Peter A. Mann, Matthias Zhang, Bing Guo, Tiannan Affiliated Hangzhou First People’s Hospital State Key Laboratory of Medical Proteomics School of Medicine Westlake University Zhejiang Province Hangzhou China Westlake Center for Intelligent Proteomics Westlake Laboratory of Life Sciences and Biomedicine Zhejiang Province Hangzhou China Biology Department Brigham Young University ProvoUT84602 United States Department of Computer Science University of Antwerp Antwerp2020 Belgium Department of Biochemistry CharitéUniversitätsmedizin Berlin Berlin Germany Biomedicine Discovery Institute Department of Biochemistry and Molecular Biology Monash University MelbourneVICVIC 3800 Australia Wellcome Genome Campus Hinxton CambridgeCB10 1SD United Kingdom Harvard Medical School Ludwig Center at Harvard United States Harvard Medical School Broad Institute Ludwig Center at Harvard Dana-Farber Cancer Institute United States Department of Biology Institute of Molecular Systems Biology ETH Zürich Zürich Switzerland Bruker Ltd. MiltonONL9T 6P4 Canada AI for Life Sciences Lab Tencent Shenzhen518057 China State Key Laboratory of Medical Proteomics AI for Science Institute Beijing100080 China Beijing Institute of Lifeomics Beijing102206 China Thermo Fisher Scientific GmbH Hanna-Kunath Str. 11 Bremen28199 Germany Informatics and Predictive Sciences Research Bristol Myers Squibb United States Department of Chemistry Fudan University Songhu Road 2005 Shanghai200438 China Department of Computer Science Luddy School of Informatics Computing and Engineering Indiana University IN47408 United States ProCan® Children’s Medical Research Institute Faculty of Medicine and Health The University of Sydney WestmeadNSW Australia La Jolla CA United States Central China Institute of Artificial Intelligence University of Waterloo Canada AI for Science Institute Center for Machine Learning Research School of Mathematical Sciences Peking University China Research Institute of Intelligent Complex Systems Fudan U

Artificial intelligence (AI) is transforming scientific research, including proteomics. Advances in mass spectrometry (MS)-based proteomics data quality, diversity, and scale, combined with groundbreaking AI techniques, are unlocking new challenges and opportunities in biological discovery. Here, we highlight key areas where AI is driving innovation, from data analysis to new biological insights. These include developing an AI-friendly ecosystem for proteomics data generation, sharing, and analysis;improving peptide and protein identification and quantification;characterizing protein-protein interactions and protein complexes;advancing spatial and perturbation proteomics;integrating multi-omics data;and ultimately enabling AI-empowered virtual cells. © 2025, CC BY.

关键词： Biotic

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Generative Artificial Intelligence in Healthcare: Ethical Considerations and Assessment Checklist

arXiv

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arXiv 2023年

作者： Ning, Yilin Teixayavong, Salinelat Shang, Yuqing Savulescu, Julian Nagaraj, Vaishaanth Miao, Di Mertens, Mayli Wei Ting, Daniel Shu Ling Ong, Jasmine Chiat Liu, Mingxuan Cao, Jiuwen Dunn, Michael Vaughan, Roger Hock Ong, Marcus Eng Sung, Joseph Jao-Yiu Topol, Eric J. Liu, Nan Centre for Quantitative Medicine Duke-NUS Medical School Singapore Singapore Centre for Biomedical Ethics National University of Singapore Singapore Singapore Wellcome Centre for Ethics and Humanities University of Oxford Oxford United Kingdom School of Medicine Imperial College London London United Kingdom Centre for Ethics Department of Philosophy University of Antwerp Antwerp Belgium Antwerp Center on Responsible AI University of Antwerp Antwerp Belgium Singapore Eye Research Institute Singapore National Eye Centre Singapore Singapore SingHealth AI Office Singapore Health Services Singapore Singapore Division of Pharmacy Singapore General Hospital Singapore Singapore Machine Learning and I-Health International Cooperation Base of Zhejiang Province Hangzhou Dianzi University Zhejiang China Artificial Intelligence Institute Hangzhou Dianzi University Zhejiang China Programme in Health Services and Systems Research Duke-NUS Medical School Singapore Singapore Department of Emergency Medicine Singapore General Hospital Singapore Singapore Lee Kong Chian School of Medicine Nanyang Technological University Singapore Singapore State Key Laboratory of Digestive Disease The Chinese University of Hong Kong Hong Kong Scripps Research Translational Institute Scripps Research La Jolla CA United States Institute of Data Science National University of Singapore Singapore Singapore Centre for Quantitative Medicine Duke-NUS Medical School 8 College Road Singapore169857 Singapore

The widespread use of ChatGPT and other emerging technology powered by generative artificial intelligence (GenAI) has drawn much attention to potential ethical issues, especially in high-stakes applications such as healthcare, but ethical discussions are yet to translate into operationalisable solutions. Furthermore, ongoing ethical discussions often neglect other types of GenAI that have been used to synthesise data (e.g., images) for research and practical purposes, which resolved some ethical issues and exposed others. We conduct a scoping review of ethical discussions on GenAI in healthcare to comprehensively analyse gaps in the current research, and further propose to reduce the gaps by developing a checklist for comprehensive assessment and transparent documentation of ethical discussions in GenAI research. The checklist can be readily integrated into the current peer review and publication system to enhance GenAI research, and may be used for ethics-related disclosures for GenAI-powered products, healthcare applications of such products and beyond. © 2023, CC BY.

关键词： Artificial intelligence

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Sketch-based Medical Image Retrieval

arXiv

引用

arXiv 2023年

作者： Kobayashi, Kazuma Gu, Lin Hataya, Ryuichiro Mizuno, Takaaki Miyake, Mototaka Watanabe, Hirokazu Takahashi, Masamichi Takamizawa, Yasuyuki Yoshida, Yukihiro Nakamura, Satoshi Kouno, Nobuji Bolatkan, Amina Kurose, Yusuke Harada, Tatsuya Hamamoto, Ryuji Division of Medical AI Research and Development National Cancer Center Research Institute 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Cancer Translational Research Team RIKEN Center for Advanced Intelligence Project 1-4-1 Nihonbashi Chuo-ku Tokyo103-0027 Japan Machine Intelligence for Medical Engineering Team RIKEN Center for Advanced Intelligence Project 1-4-1 Nihonbashi Chuo-ku Tokyo103-0027 Japan Research Center for Advanced Science and Technology The University of Tokyo 4-6-1 Komaba Meguro-ku Tokyo153-8904 Japan Medical Data Deep Learning Team Advanced Data Science Project RIKEN Information R&D and Strategy Headquarters 1-4-1 Nihonbashi Chuo-ku Tokyo103-0027 Japan Department of Experimental Therapeutics National Cancer Center Hospital 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Department of Diagnostic Radiology National Cancer Center Hospital 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Department of Neurosurgery and Neuro-Oncology National Cancer Center Hospital 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Department of Colorectal Surgery National Cancer Center Hospital 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Department of Thoracic Surgery National Cancer Center Hospital 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Radiation Safety and Quality Assurance Division National Cancer Center Hospital 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Division of Research and Development for Boron Neutron Capture Therapy National Cancer Center Exploratory Oncology Research & Clinical Trial Center 5-1-1 Tsukiji Chuo-ku Tokyo104-0045 Japan Medical Physics Laboratory Division of Health Science Graduate School of Medicine Osaka University Yamadaoka 1-7 Osaka Suita-shi565-0871 Japan Department of Surgery Kyoto University Graduate School of Medicine 54 Shogoin Kawahara-cho Sakyo-ku Kyoto606-8507 Japan

The amount of medical images stored in hospitals is increasing faster than ever;however, utilizing the accumulated medical images has been limited. This is because existing content-based medical image retrieval (CBMIR) systems usually require example images to construct query vectors;nevertheless, example images cannot always be prepared. Besides, there can be images with rare characteristics that make it difficult to find similar example images, which we call isolated samples. Here, we introduce a novel sketch-based medical image retrieval (SBMIR) system that enables users to find images of interest without example images. The key idea lies in feature decomposition of medical images, whereby the entire feature of a medical image can be decomposed into and reconstructed from normal and abnormal features. By extending this idea, our SBMIR system provides an easy-to-use two-step graphical user interface: users first select a template image to specify a normal feature and then draw a semantic sketch of the disease on the template image to represent an abnormal feature. Subsequently, it integrates the two kinds of input to construct a query vector and retrieves reference images with the closest reference vectors. Using two datasets, ten healthcare professionals with various clinical backgrounds participated in the user test for evaluation. As a result, our SBMIR system enabled users to overcome previous challenges, including image retrieval based on fine-grained image characteristics, image retrieval without example images, and image retrieval for isolated samples. Our SBMIR system achieves flexible medical image retrieval on demand, thereby expanding the utility of medical image databases. Copyright © 2023, The Authors. All rights reserved.

关键词： Search engines

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Erratum to 'Model-Based Cost-Utility Analysis of Combined Low-Dose Computed Tomography Screening for Lung Cancer, Chronic Obstructive Pulmonary Disease, and Cardiovascular Disease' [JTO Clinical and Research Reports Volume 6 Issue 5 (2025) 100813]

引用

JTO clinical and research reports 2025年第7期6卷

作者： Carina M Behr Maarten J IJzerman Michelle M A Kip Harry J M Groen Marjolein A Heuvelmans Maarten van den Berge Pim van der Harst Marleen Vonder Rozemarijn Vliegenthart Hendrik Koffijberg Health Technology and Services Research TechMed Centre University of Twente Enschede The Netherlands. Erasmus School of Health Policy & Management Erasmus University Rotterdam Rotterdam The Netherlands. Department of Pulmonary Diseases and Tuberculosis UMCG - University Medical Center Groningen Groningen The Netherlands. Department of Epidemiology University Medical Center of Groningen University of Groningen Groningen The Netherlands. Department of Pulmonary Diseases University of Groningen University Medical Center Groningen Groningen The Netherlands. Groningen Research Institute for Asthma and COPD University of Groningen University Medical Center Groningen Groningen The Netherlands. Department of Cardiology University Medical Center Utrecht Utrecht The Netherlands. Department of Radiology Medical Imaging Center University Medical Center Groningen University of Groningen Groningen The Netherlands. Machine Learning Lab Data Science Center in Health (DASH) University Medical Center Groningen University of Groningen Groningen The Netherlands.

[This corrects the article DOI: 10.1016/***.2025.100813.].

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Field-level simulation-based inference of galaxy clustering with convolutional neural networks

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Physical Review D 2024年第8期109卷 083536-083536页

作者： Pablo Lemos Liam Parker ChangHoon Hahn Shirley Ho Michael Eickenberg Jiamin Hou Elena Massara Chirag Modi Azadeh Moradinezhad Dizgah Bruno Régaldo-Saint Blancard David Spergel Department of Physics Université de Montréal Montréal 1375 Avenue Thérèse-Lavoie-Roux Montréal QC H2V 0B3 Canada Mila—Quebec Artificial Intelligence Institute Montréal 6666 Rue Saint-Urbain Montréal QC H2S 3H1 Canada Ciela—Montreal Institute for Astrophysical Data Analysis and Machine Learning Montréal Canada Center for Computational Astrophysics Flatiron Institute 162 5th Avenue New York New York 10010 USA Department of Physics Princeton University Princeton New Jersey 08544 USA Center for Cosmology and Particle Physics Department of Physics New York University New York New York 10003 USA Department of Physics Carnegie Mellon University Pittsburgh Pennsylvania 15213 USA Center for Computational Mathematics Flatiron Institute 162 5th Avenue New York New York 10010 USA Department of Astronomy University of Florida 211 Bryant Space Science Center Gainesville Florida 32611 USA Max-Planck-Institut für Extraterrestrische Physik Postfach 1312 Giessenbachstrasse 1 85748 Garching bei München Germany Waterloo Centre for Astrophysics University of Waterloo 200 University Avenue W. Waterloo Ontario N2L 3G1 Canada Department of Physics and Astronomy University of Waterloo 200 University Avenue W. Waterloo Ontario N2L 3G1 Canada Département de Physique Théorique Université de Genève 24 quai Ernest Ansermet 1211 Genève 4 Switzerland

We present the first simulation-based inference (SBI) of cosmological parameters from field-level analysis of galaxy clustering. Standard galaxy clustering analyses rely on analyzing summary statistics, such as the power spectrum Pℓ, with analytic models based on perturbation theory. Consequently, they do not fully exploit the nonlinear and non-Gaussian features of the galaxy distribution. To address these limitations, we use the SimBIG forward modeling framework to perform SBI using normalizing flows. We apply SimBIG to a subset of the Baryon Oscillation Spectroscopic Survey CMASS galaxy sample using a convolutional neural network with stochastic weight averaging to perform massive data compression of the galaxy field. We infer constraints on Ωm=0.267−0.029+0.033 and σ8=0.762−0.035+0.036. While our constraints on Ωm are in line with standard Pℓ analyses, ours on σ8 are 2.65× tighter. Our analysis also provides constraints on the Hubble constant H0=64.5±3.8 km/s/Mpc from galaxy clustering alone. This higher constraining power comes from additional non-Gaussian cosmological information, inaccessible with Pℓ. We demonstrate the robustness of our analysis by showcasing our ability to infer unbiased cosmological constraints from a series of test simulations that are constructed using different forward models than the one used in our training dataset. This work not only presents competitive cosmological constraints but also introduces novel methods for leveraging additional cosmological information in upcoming galaxy surveys like the Dark Energy Spectroscopic Instrument, Prime Focus Spectrograph, and Euclid.

关键词： Cosmology Dark energy Dark matter Large scale structure of the Universe Astrophysical & cosmological simulations Bayesian methods Deep learning machine learning Numerical simulations in gravitation & astrophysics

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Time-uniform, nonparametric, nonasymptotic confidence sequences

arXiv

引用

arXiv 2018年

作者： Howard, Steven R. Ramdas, Aaditya McAuliffe, Jon Sekhon, Jasjeet Departments of Statistics Political Science UC Berkeley Departments of Statistics and Data Science United States Machine Learning Carnegie Mellon The Voleon Group United States

A confidence sequence is a sequence of confidence intervals that is uniformly valid over an unbounded time horizon. Our work develops confidence sequences whose widths go to zero, with nonasymptotic coverage guarantees under nonparametric conditions. We draw connections between the Cramér-Chernoff method for exponential concentration, the law of the iterated logarithm (LIL), and the sequential probability ratio test—our confidence sequences are time-uniform extensions of the first;provide tight, nonasymptotic characterizations of the second;and generalize the third to nonparametric settings, including sub-Gaussian and Bernstein conditions, self-normalized processes, and matrix martingales. We illustrate the generality of our proof techniques by deriving an empirical-Bernstein bound growing at a LIL rate, as well as a novel upper LIL for the maximum eigenvalue of a sum of random matrices. Finally, we apply our methods to covariance matrix estimation and to estimation of sample average treatment effect under the Neyman-Rubin potential outcomes model. Copyright © 2018, The Authors. All rights reserved.

关键词： Eigenvalues and eigenfunctions

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Local and Global Information Preserved Network Embedding

Local and Global Information Preserved Network Embedding

引用

International Conference on Advances in Social Network Analysis and Mining, ASONAM

作者： Yao Ma Suhang Wang Jiliang Tang Data Science and Engineering Lab Michigan State University East Lansing MI USA Data Mining and Machine Learning Lab Arizona State University Tempe AZ USA

ISBN: (纸本)9781538660522

Networks such as social networks, airplane networks, and citation networks are ubiquitous. To apply advanced machine learning algorithms to network data, low-dimensional and continuous representations are desired. To achieve this goal, many network embedding methods have been proposed recently. The majority of existing methods facilitate the local information i.e. local connections between nodes, to learn the representations, while neglecting global information (or node status), which has been proven to boost numerous network mining tasks such as link prediction and social recommendation. In this paper, we study the problem of preserving local and global information for network embedding. In particular, we introduce an approach to capture global information and propose a network embedding framework LOG, which can coherently model LOcal and Global information. Experiments demonstrate the effectiveness of the proposed framework.

关键词： Task analysis Social network services Prediction algorithms Blogs Mathematical model Training Linear programming

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Feature extraction for hyperspectral imagery: The evolution from shallow to deep

arXiv

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arXiv 2020年

作者： Rasti, Behnood Hong, Danfeng Hang, Renlong Ghamisi, Pedram Kang, Xudong Chanussot, Jocelyn Benediktsson, Jon Atli Machine Learning Group Exploration Division Helmholtz Institute Freiberg for Resource Technology Helmholtz-Zentrum Dresden-Rossendorf Freiberg09599 Germany Univ. Grenoble Alpes CNRS Grenoble INP GIPSAlab Grenoble38000 France Jiangsu Key Laboratory of Big Data Analysis Technology School of Automation Nanjing University of Information Science and Technology Nanjing210044 China Machine Learning Group Exploration Division Helmholtz Institute Freiberg for Resource Technology Helmholtz-Zentrum Dresden-Rossendorf Freiberg09599 Germany College of Electrical and Information Engineering Hunan University Changsha410082 China Key Laboratory of Visual Perception and Artificial Intelligence of Hunan Province Changsha410082 China Univ. Grenoble Alpes Inria CNRS Grenoble INP LJK GrenobleF-38000 France Faculty of Electrical and Computer Engineering University of Iceland Reykjavik101 Iceland Faculty of Electrical and Computer Engineering University of Iceland Reykjavik107 Iceland

The final version of the paper can be found in IEEE Geoscience and Remote Sensing Magazine. Hyperspectral images provide detailed spectral information through hundreds of (narrow) spectral channels (also known as dimensionality or bands) with continuous spectral information that can accurately classify diverse materials of interest. The increased dimensionality of such data makes it possible to significantly improve data information content but provides a challenge to the conventional techniques (the so-called curse of dimensionality) for accurate analysis of hyperspectral images. Feature extraction, as a vibrant field of research in the hyperspectral community, evolved through decades of research to address this issue and extract informative features suitable for data representation and classification. The advances in feature extraction have been inspired by two fields of research, including the popularization of image and signal processing as well as machine (deep) learning, leading to two types of feature extraction approaches named shallow and deep techniques. This article outlines the advances in feature extraction approaches for hyperspectral imagery by providing a technical overview of the state-of-the-art techniques, providing useful entry points for researchers at different levels, including students, researchers, and senior researchers, willing to explore novel investigations on this challenging topic. In more detail, this paper provides a bird's eye view over shallow (both supervised and unsupervised) and deep feature extraction approaches specifically dedicated to the topic of hyperspectral feature extraction and its application on hyperspectral image classification. Additionally, this paper compares 15 advanced techniques with an emphasis on their methodological foundations in terms of classification accuracies. Furthermore, to push this vibrant field of research forward an impressive amount of codes and libraries is shared at: https://***/Behnoo

关键词： Feature extraction

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Optimal crowd navigation via spatio-temporal multidimensional collective data analysis

引用

NTT Technical Review 2017年第9期15卷 1-7页

作者： Naya, Futoshi Miyamoto, Masaru Ueda, Naonori Innovative Communication Laboratory NTT Communication Science Laboratories Japan Service Innovation Laboratory NTT Service Evolution Laboratories Japan Machine Learning and Data Science Center NTT Communication Science Laboratories Japan

We introduce technology for predicting the risk of congestion in the near future from real-time observational data of people or automobile flows and for automatically deriving an optimal crowd navigation plan online to avoid that risk. This technology can deal with unforeseen situations by performing simulations based on machine learning. Our aim in establishing this technology is to help construct a safe and secure and more comfortable social infrastructure.

关键词： Navigation

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