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Cover Picture: Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers (Angew. Chem. Int. Ed. 13/2011)

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Angewandte Chemie International Edition 2011年第13期50卷

作者： Dr. Shutao Wang Dr. Kan Liu Dr. Jian Liu Dr. Zeta T.-F. Yu Xiaowen Xu Libo Zhao Tom Lee Dr. Eun Kyung Lee Jean Reiss Prof. Yi-Kuen Lee Prof. Leland W. K. Chung Prof. Jiaoti Huang Prof. Matthew Rettig Prof. David Seligson Dr. Kumaran N. Duraiswamy Prof. Clifton K.-F. Shen Prof. Hsian-Rong Tseng Beijing National Laboratory for Molecular Sciences Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences Beijing (P. R. China) College of Electronics and Information Engineering Wuhan Textile University Wuhan (P. R. China) Uro-oncology Research Program Samuel Oschin Comprehensive Cancer Institute Cedars Sinai Medical Center Los Angeles (USA) Department of Pathology and Laboratory Medicine University of California Los Angeles (USA) Department of Mechanical Engineering The Hong Kong University of Science and Technology (Hong Kong) Department of Urology University of California Los Angeles (USA)

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Friction feedforward compensation and position feedforward in CNC machines

Friction feedforward compensation and position feedforward i...

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7th Annual International Conference on Electrical engineering/electronics, Computer, Telecommunications and Information technology, ECTI-CON 2010

作者： Suteeratanapirom, Wijin Rattanawaorahirankul, Rapeepong Laosapan, Chutima Sanposh, Peerayot Chayopitak, Nattapon Tungpimolrut, Kanokvate Kunieda, Hiroaki TAIST Tokyo Tech ICTES Program Department of Electrical Engineering Kasetsart University 50 Phahonyothin Rd. Ladyao Jatujak Bangkok 10903 Thailand Intelligent Mechatronics Automation Robotics and Control Laboratory Department of Electrical Engineering Kasetsart University 50 Phahonyothin Rd. Ladyao Jatujak Bangkok 10903 Thailand Industrial Control and Automation Laboratory National Electronics and Computer Technology Center 112 Thailand Science Park Phahonyothin Rd. Klong 1 Klong Luang Pathumthani 12120 Thailand Department of Electrical and Electronic Engineering Tokyo Institute of Technology S3-65 2-12-1 Ookayama Meguro-ku Tokyo 152-8550 Japan

ISBN: (纸本)9789746724913

This research proposes a method to eliminate friction effect and reduced tracking error on CNC milling machines. A CNC milling machine has many connected mechanical components which have friction effects such as ball screws and rails. To control servo motors which are used to drive X-Y table in CNC milling machine, the conventional PID controller is widely used. In this research, Panasonic motor driver is set to the torque control mode. To compensate the friction effects, the friction feedforward compensation method is proposed. Moreover, to reduce the position tracking error, position feedforward controller is used. The simulation and implementation of position control in one axis of PID with Friction Feedforward Compensation and Position Feedforward Controller (FFC-PFC) are presented.

关键词： Friction

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Design and fabrication of nanoscale antireflection structures with linearly graded refractive index

Design and fabrication of nanoscale antireflection structure...

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2010 10th IEEE Conference on Nanotechnology, NANO 2010

作者： Song, Young Min Jang, Sung Jun Choi, Hee Ju Yu, Jae Su Lee, Yong Tak Department of Information and Communications Gwangju Institute of Science and Technology 1 Oryong-dong Buk-gu Gwangju 500-712 Korea Republic of Graduate Program of Photonics and Applied Physics Gwangju Institute of Science and Technology 1 Oryong-dong Buk-gu Gwangju 500-712 Korea Republic of Department of Electronic Engineering Kyung Hee University 1 Seocheon-dong Giheung-gu Yongin-si Gyeonggi-do 446-701 Korea Republic of Department of Nanobio Materials and Electronics Gwangju Institute of Science and Technology 1 Oryong-dong Buk-gu Gwangju 500-712 Korea Republic of

ISBN: (纸本)9781424470334

We demonstrate nanoscale antireflection structures on GaAs substrate with linearly graded effective refractive index using a lenslike shape transfer for broadband light-absorbing device application. From reflectance calculation of cone- and parabola-shaped subwavelength grating (SWG) structures, it is found that the parabola shaped structures has lower mean reflectance compared to that of the cone shaped structures over a wide wavelength range. The fabricated SWG structures with parabola shape show the reflectance of below 5 % in a 300-1200 nm wavelength range. ©2010 IEEE.

关键词： Reflection

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Mechanical cell lysis chip with ultra-sharp nano-blade array fabricated by crystalline wet etching of (110) silicon

Mechanical cell lysis chip with ultra-sharp nano-blade array...

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IEEE International Conference on Micro Electro Mechanical Systems

作者： Sung-Sik Yun Sang Youl Yoon Jong-Hyun Lee Sung Yang Department of Nanobio Materials and Electronics GIST Gwangju South Korea Graduate Program of Medical System Engineering GIST Gwangju South Korea Department of Mechatronics GIST Gwangju South Korea Gwangju Institute of Science and Technology Gwangju KR

ISBN: (纸本)9781424457618;9781424457649

This paper presents a mechanical cell lysis microfluidic chip with an ultra-sharp nano-blade array fabricated by simple and cost effective crystalline wet etching of (110) silicon. The ultra-sharp nano-blade array is simply formed by the undercutting during the crystalline wet etching process. The sharpness of the silicon nano-blade is less than 10 nm after the undercutting. EL4 mouse T-lymphoma cells are used for the demonstration of the mechanical lysis chip, and the cells are easily disrupted by the silicon nano-blade array without helping of additional reagents or electrical sources. The time-resolved observation of the mechanical cell lysis shows that the developed silicon nano-blade array is enough to easily disrupt the cell membrane even at very low flow rate of 0.7 ¿¿/hr.

关键词： Crystallization Wet etching Silicon

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Impedance measurement of normal and cancerous human breast cells using a microfluidic tunnel

Impedance measurement of normal and cancerous human breast c...

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IEEE SENSORS

作者： Giseok Kang Sung-Kil Lee Sung Keun Yoo Sung Yang Jong-Hyun Lee Graduate-program of Medical System Engineering Gwangju Institute of Science and Technology Gwangju South Korea School of Information and Mechatronics Gwangju Institute of Science and Technology Gwangju South Korea Department of Nanobio Materials and Electronics Gwangju Institute of Science and Technology Gwangju South Korea Gwangju Institute of Science and Technology Gwangju KR

In this paper, a novel microelectrical impedance spectroscopy (μEIS) with three-dimensional interdigitated electrodes (3D-IDE) is developed to differentiate normal and cancerous cells. The device utilizes a microfluidic tunnel structure, which forces cells to be squeezed. Thus, the enlarged contact area between cells and electrodes allows the device to measure the intrinsic electrical signal of the cells with a higher sensitivity than a noncontact case. The cell squeezing is realized by fabricating smaller microfluidic channel than cell size. The electrical impedances are measured through 3D-IDE. The device well distinguishes normal human breast cell (MCF-10A) and early-stage human breast cancer cell (MCF-7) with a phase difference of 1.42° at 500 kHz. The proposed device also features a high repeatability because the phase change is as small as 0.27° (which is sufficiently smaller than the phase difference between normal and cancer cell) before and after the each cell assay.

关键词： Impedance Electrodes Microfluidics Impedance measurement Breast cancer

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High-input Impedance Voltage-mode Universal Filter Using CCCCTAs

High-input Impedance Voltage-mode Universal Filter Using CCC...

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electronics, Computer, Telecommunications and Information technology International Conference on Electrical engineering/electronics, Computer, Telecommunications and Information technology

作者： Winai Jaikla Abhirup Lahiri Adisorn Kwawsibsame Montree Siripruchyanun Electric and Electronic Program Faculty of Industrial Technology Suan Sunandha Rajabhat University Dusit Bangkok THAILAND Part of the work done while the author was with Division of Electronics and Communications Netaji Subhas Institute of Tec hnology Electronics Department Lanna Polytechnical College Chiangmai Department of Teacher Training in Electrical Engineering Faculty of Technical Education King Mongkut's University of Technology North Bangkok

ISBN: (纸本)9781424456062

This article presents a voltage-mode universal biquadratic filter (low-pass, high-pass, band-pass functions), based on current controlled current conveyor transconductance amplifiers (CCCCTAs). The features of the circuit are that: the quality factor and pole frequency can be tuned orthogonally via the input bias currents: the circuit description is very simple, consisting of merely 3 CCCCTAs and 2 grounded capacitors. Without any external resistors, requiring no component matching conditions, and using only grounded elements, the proposed circuit is very appropriate to further develop into an integrated circuit. Moreover, the proposed circuit enables easy cascading in voltage-mode, due to high-input impedances. The PSPICE simulation results are depicted. The given results agree well with the theoretical anticipation. The power consumption is approximately 4.08mW at ±2.5V power supply voltages.

关键词： Impedance Band pass filters Tuned circuits Low pass filters Voltage control Transconductance Q factor Frequency Capacitors Resistors

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A multichannel SPR biosensor with a fixed detection system

A multichannel SPR biosensor with a fixed detection system

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2010亚洲光电子会议先进的传感系统及其应用分会场

作者： Boonsong Sutapun Armote Somboonkaew Ratthasart Amrit Supanit Porntheeraphat Nongluck Houngkamhang Toemsak Srikhirin Photonics Technology Laboratory National Electronics and Computer Technology Center Thai Microelectronics Center National Electronics and Computer Technology Center112 Thailand Science Park Pahol Yothin Rd.Klong LuangPathumthaniThailand 12120 Materials Science and Engineering Program and Physics Department Faculty of ScienceMahidol UniversityRama 6 Rd.RajathaveeBangkok 10400Thailand

Surface plasmon resonance （SPR） sensors with spectral interrogation provide a high refractive index resolution, a large dynamic range and a fixed optical detection module. In this work, we propose a new spectral detection unit that uses only one spectrometer to measure the SPR spectrum from multiple sensing spots rapidly and serially without any mechanical movement. This spectral detection unit is designed based on a spatial light modulator （SLM） configured as a programmable optical aperture for the spectrometer. To demonstrate this concept, a five-channel SPR sensor was built based on the proposed multichannel detection unit and we evaluated the device performance using a refractive index test. The average device refractive index resolution was 1.4 × 10 -6 refractive index units （RIU）.

关键词： Surface plasmon resonance SPR multichannel detection optical biosensor biosensor

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A multi-source micro power generator employing thermal and vibration energy harvesting

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Procedia engineering 2010年 5卷 1176-1179页

作者： Hakan Töreyin Emre Topal Haluk Külah Middle East Technical University Department of Electrical and Electronics Engineering Ankara Turkey Middle East Technical University Micro and Nano Technologies Graduate Program Ankara Turkey METU-MEMS Research and Application Center Ankara TURKEY * Currently with School of Electrical and Computer Engineering Georgia Institute of Technology Atlanta U.S.A.

This paper introduces a new cantilever type multi-source energy harvester generating electric power from both ambient heat and vibration. Harvesting energy from vibration was realized by electromagnetic conversion, whereas the energy generation from heat was supplied by making use of Seebeck effect of Cr–Al thermocouples implemented on the microcantilevers. The measured average Seebeck coefficient is 12 μV/K per thermocouple. A total voltage of 3.3 mV was generated from the thermoelectric part and 13.4 mV from the electromagnetic part of the device. Measured total power from the fabricated chip is 1.91 nW (1.12 nW from vibration, 0.79 nW from thermoelectric).

关键词： Energy harvesting Thermoelectric, electromagnetic Vibration Micro power generation

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Titelbild: Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers (Angew. Chem. 13/2011)

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Angewandte Chemie 2011年第13期123卷

作者： Shutao Wang Kan Liu Jian Liu Zeta T.‐F. Yu Xiaowen Xu Libo Zhao Tom Lee Eun Kyung Lee Jean Reiss Yi‐Kuen Lee Leland W. K. Chung Jiaoti Huang Matthew Rettig David Seligson Kumaran N. Duraiswamy Clifton K.‐F. Shen Hsian‐Rong Tseng Beijing National Laboratory for Molecular Sciences Key Laboratory of Organic Solids Institute of Chemistry Chinese Academy of Sciences Beijing (P. R. China) Department of Molecular and Medical Pharmacology Crump Institute for Molecular Imaging (CIMI) California NanoSystems Institute (CNSI) Institute for Molecular Medicine (IMED) University of California Los Angeles 570 Westwood Plaza Building 114 Los Angeles CA 90095‐1770 (USA) Fax: (+1) 310‐206‐8975 http://labs.pharmacology.ucla.edu/tsenglab/ College of Electronics and Information Engineering Wuhan Textile University Wuhan (P. R. China) Uro‐oncology Research Program Samuel Oschin Comprehensive Cancer Institute Cedars Sinai Medical Center Los Angeles (USA) Department of Pathology and Laboratory Medicine University of California Los Angeles (USA) Department of Mechanical Engineering The Hong Kong University of Science and Technology (Hong Kong) Department of Urology University of California Los Angeles (USA)

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Highly Efficient Capture of Circulating Tumor Cells by Using Nanostructured Silicon Substrates with Integrated Chaotic Micromixers†

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Angewandte Chemie 2011年第13期123卷

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