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Polyzwitterionic Hydrogels for Highly Efficient High Salinity Solar Desalination

Angewandte Chemie 2022年第36期134卷

作者： Chuxin Lei Weixin Guan Youhong Guo Wen Shi Yuyang Wang Prof. Keith P. Johnston Prof. Guihua Yu Materials Science and Engineering Program and Walker Department of Mechanical Engineering The University of Texas at Austin Austin TX 78712 USA McKetta Department of Chemical Engineering The University of Texas at Austin Austin TX 78712 USA

Interfacial solar vapor generation (SVG) is regarded as a promising and sustainable strategy for clean water production. While many materials have demonstrated excellent evaporation rates under one sun, it remains challenging to design solar evaporators without compromising SVG performance in high-salinity brines (≥10 wt %). Herein, polyzwitterionic hydrogels (PZHs) are proposed as a novel platform for high-salinity solar desalination. Taking advantage of the unique anti-polyelectrolyte effects, PZHs can trap salt ions from the brine water to form a more hydrated polymer network, leading to enhanced SVG performance. PZHs exhibit an exceptional solar evaporation rate of 4.14 kg m −2 h −1 in 10 wt % brine, which is ≈20 % higher than that in pure water. It is anticipated that salt-responsive PZHs may provide insights for the design of next-generation solar desalination systems.

关键词： Anti-Polyelectrolyte Effects Hydration Polyzwitterionic Hydrogel Solar Desalination Solar Vapor Generation

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HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs (vol 31, pg 1757, 2012)

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ONCOGENE 2021年第8期40卷 1552-1553页

作者： Zhang, H. Wong, C. C. L. Wei, H. Gilkes, D. M. Korangath, P. Chaturvedi, P. Schito, L. Chen, J. Krishnamachary, B. Winnard, P. T., Jr. Raman, V. Zhen, L. Mitzner, W. A. Sukumar, S. Semenza, G. L. Vascular Program Institute for Cell Engineering The Johns Hopkins University School of Medicine Baltimore MD USA Department of Oncology The Johns Hopkins University School of Medicine Baltimore MD USA School of Life Science The University of Science and Technology of China Hefei Anhui China McKusick-Nathans Institute of Genetic Medicine The Johns Hopkins University School of Medicine Baltimore MD USA University of Rome ‘La Sapienza’ Rome Italy Departments of Pediatrics Medicine Radiation Oncology and Biological Chemistry The Johns Hopkins University School of Medicine Baltimore MD USA Department of Radiology The Johns Hopkins University School of Medicine Baltimore MD USA Division of Physiology The Johns Hopkins University School of Public Health Baltimore MD USA

A Correction to this paper has been published: https://***/10.1038/s41388-020-01618-z

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Critical success factors of external sustainability: Multiple-case studies

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AIP Conference Proceedings 2025年第1期3120卷

作者： Nur Puji Lestari Stefania Boscari Dawi Karomati Baroroh Program of Industrial Technology Institute of Technology and Science Nahdlatul Ulama Pekalongan Pekalongan 51173 Indonesia Faculty of Economic and Business University of Groningen Groningen 9172 Netherlands Department of Mechanical and Industrial Engineering Universitas Gadjah Mada Yogyakarta 55281 Indonesia

Sustainable supply chain management (SSCM) is crucial, yet it is still difficult to implement in companies. This happens because there are various factors known as critical success factors (CSFs) that have a role in the implementation of plans and operational performance in sustainability. The study used multiple-case studies and analyzed four different types of companies that have implemented external sustainability. Based on the within-case analysis, a list of CSFs for external sustainability implementation that differs between organizations is generated for each case. Furthermore, the effects of contingencies toward CSFs implementation are established.

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An artificial intelligence method for vessel detection in images of cardiac catheterization

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Informatics in Medicine Unlocked 2023年 39卷

作者： Chien, Ting-Ying Ting, Hsien-Wei Li, Hao-Wei Chang, Hsiao-Huang Department of Computer Science and Engineering Yuan Ze University 320 Taoyuan City Taiwan Graduate Program in Biomedical Informatics Yuan Ze University 320 Taoyuan City Taiwan Innovation Center for Big Data and Digital Convergence Yuan Ze University 320 Taoyuan City Taiwan Department of Neurosurgery Taipei Hospital Ministry of Health and Welfare 242 New Taipei City Taiwan Division of Cardiovascular Surgery Department of Surgery Taipei Veterans General Hospital Taipei 11217 Taiwan Department of Surgery School of Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan

Coronary artery disease (CAD) is one of the top ten leading causes of death in countries worldwide. There are several methods used by physicians to diagnose CAD. One common method is the use of X-ray angiogram (XRA) images. When employing a computer-aided automatic analysis method to locate blood vessels in XRA images, problems such as complex background noise, low contrast, and difficulty in separating blood vessels from the background are encountered, especially for blood vessels with a low contrast to the background noise. In this study, we used various image preprocessing methods to highlight blood vessels from complex backgrounds and different types of blood vessel, followed by the employment of four superpixel segmentation methods to partition an image into multiple segments, and finally the utilization of Weighted Voting to determine the best superpixel algorithm. A genetic algorithm was used to identify the best weights by which to determine the locations of blood vessels in images of cardiac catheterization. Our proposed method achieved an average F1-score of 73.4% in the analysis of five patients, which was better than the other superpixel algorithms tested. The results of this research will be helpful for future SYNTAX score analysis. © 2023

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COVID-19 Associated Bacteremia withChryseobacterium indologenesCo-HarboringblaIND-2,blaCIAandblaCcrA

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Infection and Drug Resistance 2022年 15卷 167-170页

作者： Ting-Kuang Yeh Zong-Hao Li Yao-Ting Huang Po-Yu Liu 1 Division of Infectious Diseases Department of Internal Medicine Taichung Veterans General Hospital Taichung Taiwan 2 Department of Computer Science and Information Engineering National Chung Cheng University Chiayi Taiwan 1 Division of Infectious Diseases Department of Internal Medicine Taichung Veterans General Hospital Taichung Taiwan3 Ph.D. Program in Translational Medicine National Chung Hsing University Taichung Taiwan4 Rong Hsing Research Center for Translational Medicine National Chung Hsing University Taichung Taiwan

We report a COVID-19 case with carbapenem resistantChryseobacterium indologenesbacteremia. Whole genome sequencing identified the presence ofblaIND-2,blaCIAandblaCcrA. To our knowledge, this is the first report ofChryseobacterium indologenescomplicating COVID-19 and the detection ofblaCcrAinC. indologenes. The presence ofblaCcrAinChryseobacteriumwas overlooked previously may related to substantial sequence divergence with the original allele inBacteroides fragilis. Antimicrobial resistance (AMR) is a challenge to global health in the age of COVID-19 pandemic. Further study and surveillance of underlying mechanisms is needed.

关键词： COVID-19 SARS-CoV-2 Chryseobacterium indologenes resistance

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Dopaminergic and Serotoninergic Neurotoxicity of Lanthanide Phosphate (Tbpo4) in Developing Zebrafish

SSRN

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SSRN 2023年

作者： Chen, Siying Wang, Xiaohong Ye, Xiaolin Qin, Yingju Wang, Haiqing Liang, Zhenda Zhu, Lishan Zhou, Li Martyniuk, Christopher J. Yan, Bing Institute of Environ. Res. at Greater Bay Area Key Laboratory for Water Quality and Conservation of the Pearl River Delta Ministry of Education Guangzhou University Guangzhou510006 China Center for Environmental and Human Toxicology Department of Physiological Sciences College of Veterinary Medicine UF Genetics Institute Interdisciplinary Program in Biomedical Sciences in Neuroscience University of Florida GainesvilleFL32611 United States School of Environmental Science and Engineering Shandong University Shandong Jinan250100 China

Rare earth elements (REEs) are exploited for global use in manufacturing. Such activities result in their release into the environment and the transformation into more stable phosphate deposition. The objective of this study was to evaluate molecular and behavioral changes of zebrafish exposed to the synthesized terbium phosphate (TbPO4) at concentrations of 10, 20, and 50 mg/L and to determine its potential for neurotoxicity. Metabolomic profiling and assessment of transcripts and proteins were conducted to uncover the molecular mechanisms underlying TbPO4 with emphasis on neurotransmitter systems. Exposure to 20 mg/L TbPO4 induced larval hyperactivity and perturbed the cholinergic system in zebrafish. Based on metabolomics, dopamine (DA), serotonin (5-HT), and many of their precursors and metabolites were decreased in abundance by TbPO4. In addition, the expression levels of transcripts related to the synthesis, transport, receptor binding, and metabolism of DA and 5-HT were analyzed at the mRNA and protein levels. Transcript and protein levels for tyrosine hydroxylase (TH), the rate-limiting enzyme for DA synthesis, were down-regulated in larval fish. Monoamine oxidase (MAO), an enzyme that catabolizes monoamines DA and 5-HT, also reduced mRNA abundance. We hypothesize that DA synthesis and monoamine metabolism are associated with behavioral alterations. In addition, a mechanism for the disruption of neurotransmitter systems by TbPO4 may be the apoptosis of neurons. This study elucidates putative mechanisms and exposure risks to wildlife and humans by characterizing phosphatic REE-induced neurotoxicity in developing zebrafish. © 2023, The Authors. All rights reserved.

关键词： Rare earth elements

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Correction to: Identifying Abnormal CFRP Holes Using Both Unsupervised and Supervised Learning Techniques on In-Process Force, Current, and Vibration Signals

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International Journal of Precision engineering and Manufacturing 2022年第10期23卷 1225-1225页

作者： Svinth, Christian N. Wallace, Scott Stephenson, Daniel B. Kim, Dave Shin, Kangwoo Kim, Hyo-Young Lee, Seok-Woo Kim, Tae-Gon Computer Science Program School of Engineering and Computer Science Washington State University Vancouver USA Mechanical Engineering Program School of Engineering and Computer Science Washington State University Vancouver USA Korea Institute of Industrial Technology (KITECH) Cheonan‑si Republic of Korea Department of Mechatronics Engineering Tech University of Korea (TU Korea) Siheung-si Korea

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Hydrogenated SnO for p-channel oxide thin film transistor 57th

Hydrogenated SnO for p-channel oxide thin film transistor

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57th SID International Symposium, Seminar and Exhibition, Display Week, 2020

作者： Lee, Alex Wootae Matsuzaki, Kosuke Nomura, Kenji Materials Science and Engineering program University of California San Diego La JollaCA92092 United States Materials and Structures Laboratory Tokyo Institute of Technology Nagatsuta Midori-ku Yokohama226-8503 Japan Department of Electrical and Computer Engineering University of California San Diego La JollaCA92092 United States

Subgap defect termination for p-type Tin monoxide (SnO) is developed with thermal annealing in hydrogen ambient for p-channel oxide thin-film transistor (TFT). High-performance p-channel oxide TFT with the TFT mobility of ~1.4-1.8 cm2/Vs and large on-to-off current as large as 105 was demonstrated. Hydrogen-containing annealing also maintains SnO phase stable up to 390 °C and effectively reduces the subgap defect, which offer the improvement in TFT characteristics. © 2020 SID.

关键词： Tin oxides

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Novel Biosynthesis of Spherical Tungsten Trioxide Nanoparticles for Sustainable Photocatalytic Application

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Applied Organometallic Chemistry 2025年第6期39卷

作者： Nazish Parveen Kholoud M. Alnahdi Shada A. Alsharif Sajid Ali Ansari Mohd Zahid Ansari Ahmad Umar Chawki Awada Haya Abdullah Al-Dosari Department of Chemistry College of Science King Faisal University Al-Hasa Saudi Arabia Saudi Arabia Department of Physics Faculty of Science University of Tabuk Tabuk Saudi Arabia University College of Umluj University of Tabuk Tabuk Saudi Arabia Department of Physics College of Science King Faisal University Hofuf Al-Ahsa Saudi Arabia Chemical Engineering Program Texas A&M University at Qatar Doha Qatar Department of Chemistry College of Science and Arts and Promising Centre for Sensors and Electronic Devices (PCSED) Najran University Najran Saudi Arabia STEM Pioneers Training Lab Najran University Najran Saudi Arabia Department of Materials Science and Engineering The Ohio State University Columbus Ohio USA

We developed a novel method for synthesizing tungsten trioxide nanoparticles, utilizing orange juice as a sustainable and economical catalyst. This innovative approach eliminates the need for expensive metals and harsh chemicals. The natural components of orange juice, particularly ascorbic acid and citric acid, play a crucial role in the formation and stabilization of these nanoparticles. We thoroughly tested the synthesized nanoparticles using a suite of analytical techniques, including X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, and Fourier transform infrared spectroscopy. The results were compelling. When exposed to UV light, the nanoparticles were able to degrade approximately 95% of the model pollutant, methyl orange, demonstrating a rapid and efficient performance. Without the presence of these nanoparticles, the degradation of the pollutant was minimal. This confirms the effectiveness of the tungsten trioxide nanoparticles as a potent and environmentally friendly solution for pollutant degradation in various applications. This method not only offers a green alternative to traditional nanoparticle synthesis but also highlights the potential of using common natural resources in advanced environmental applications.

关键词： biosynthesis photocatalytic activity sustainable materials UV light WO3 NPs

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Therapeutic targeting of hepatocellular carcinoma cells with antrocinol, a novel, dual-specificity, small-molecule inhibitor of the KRAS and ERK oncogenic signaling pathways

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Chemico-Biological Interactions 2023年第1期370卷 110329页

作者： Hsu, Chia-Hung Weng, Pei-Wei Chen, Ming-Yao Yeh, Chi-Tai Setiawan, Syahru Agung Yadav, Vijesh Kumar Wu, Alexander T.H. Tzeng, David T.W. Gong, Jian-Xian Yang, Zhen Tzeng, Yew-Min Department of Emergency Medicine Shuang Ho Hospital Taipei Medical University New Taipei City 23561 Taiwan Graduate Institute of Injury Prevention and Control College of Public Health Taipei Medical University Taipei City 11031 Taiwan Department of Emergency Medicine School of Medicine Taipei Medical University Taipei 11031 Taiwan Department of Orthopaedics School of Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan Department of Orthopaedics Shuang Ho Hospital Taipei Medical University New Taipei City 23561 Taiwan Graduate Institute of Biomedical Materials and Tissue Engineering College of Biomedical Engineering Taipei Medical University Taipei 11031 Taiwan Division of Gastroenterology and Hepatology Department of Internal Medicine Shuang Ho Hospital New Taipei City 23561 Taiwan Division of Gastroenterology and Hepatology Department of Internal Medicine School of Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan Continuing Education Program of Food Biotechnology Applications College of Science and Engineering National Taitung University Taitung 95092 Taiwan International Ph.D. Program in Medicine College of Medicine Taipei Medical University Taipei 11031 Taiwan Ph.D. Program of Translational Medicine College of Medical Science and Technology Taipei Medical University Taipei 11031 Taiwan School of Life Sciences The Chinese University of Hong Kong 999077 Hong Kong Lifebit London EC2A 2AP United Kingdom Laboratory of Chemical Genomics School of Chemical Biology and Biotechnology Peking University Shenzhen Graduate School Shenzhen 518055 China State Key Laboratory of Bioorganic Chemistry and Molecular Engineering of the Ministry of Education and Beijing National Laboratory for Molecular Science College of Chemistry and Molecular Engineering Peking University Beijing 100871 China Shenzhen Bay Laboratory Shenzhen 518055 China Department of Applied Science National Taitung University Taitung

Until recently, sorafenib has been the only treatment approved by the U.S. Food and Drug Administration for patients with advanced hepatocellular carcinoma (HCC). Some patients, however, exhibit resistance to this treatment and subsequently experience cancer progression, recurrence, or death. Therefore, identifying a new alternative treatment for patients with little or no response to sorafenib treatment is vital. In this study, we explored the therapeutic potential and underlying molecular mechanism of antrocinol ((3aS,4R,6aS,10aR)-4-(hydroxymethyl)-7,7-dimethyldecahydro-1H-naphtho[1,8a-c]furan-1-one) in patients with HCC. The results indicated that antrocinol was more therapeutically effective than antrocin, Stivarga, and sorafenib against HCC cell lines. Antrocinol also substantially suppressed the expression of KRAS-GTP, p-MEK1/2, p-ERK1/2, and p-AKT in the Huh7 cell line. Additionally, antrocinol-induced apoptosis in the Huh7 cell line, inhibited the formation of tumorspheres, and suppressed the expression of cancer stem cell markers CD133, KLF4, CD44, OCT4, SOX2, and c-Myc. Animal studies revealed that antrocinol alone considerably suppressed tumor growth in nonobese diabetic/severe combined immunodeficient mice inoculated with Huh7 tumorspheres. It also synergistically enhanced the anticancer effect of sorafenib, resulting in enhanced suppression of tumor growth (p < 0.001) and tumorsphere formation (p < 0.001). In tumor samples resected from mice treated with antrocinol alone or in combination with sorafenib, immunohistochemical analysis revealed an increase in BAX expression and a decrease in ERK and AKT protein expression. To the best of our knowledge, this is the first report of the anti-HCC activity of antrocinol. With its higher therapeutic efficacy than that of sorafenib, antrocinol is a candidate drug for patients with HCC who demonstrate little or no response to sorafenib treatment. © 2022 Elsevier B.V.

关键词： Antrocinol Cancer stemness Hepatocellular carcinoma KRAS/AKT/ERK axis Sorafenib

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