We introduce spatial channel networks (SCNs) to the interconnection of data center networks (DCNs). We propose an integer linear programming (ILP) model to solve the routing and spectrum assignment problem for SCN-bas...
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In this paper, we utilize a diagonally dominant structure for the decentralized stabilization of unknown nonlinear time-delayed networks. Generalizing the idea of virtual contraction analysis to time-delayed systems, ...
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To minimize the disturbance of the Tunnel Boring Machine (TBM) cutterhead on the surrounding rock during the coal mine roadway excavation process and ensure that the cutterhead rotation speed achieves fast tracking pe...
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This paper presents an end-to-end wireless digital twin platform constructed using open-source software and open data to enhance the evaluation of mobile communication systems. The proposed open wireless digital twin ...
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Traditional lithography techniques are currently facing challenges, including high costs and the susceptibility of mask plates to damage. This research aims to elucidate the feasibility and technical constraints of a ...
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Purpose:This study explores the underlying research topics regarding CRISPR based on the LDA model and figures out trends in knowledge transfer from science to technology in this area over the latest 10 ***/methodolog...
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Purpose:This study explores the underlying research topics regarding CRISPR based on the LDA model and figures out trends in knowledge transfer from science to technology in this area over the latest 10 ***/methodology/approach:We collected publications on CRISPR between 2011 and2020 from the Web of science,and traced all the patents citing them from ***.15,904 articles and 18,985 patents in total are downloaded and *** LDA model was applied to identify underlying research topics in related *** addition,some indicators were introduced to measure the knowledge transfer from research topics of scientific publications to IPC-4 classes of ***:The emerging research topics on CRISPR were identified and their evolution over time ***,a big picture of knowledge transition from research topics to technological classes of patents was *** found that for all topics on CRISPR,the average first transition year,the ratio of articles cited by patents,the NPR transition rate are respectively 1.08,15.57%,and 1.19,extremely shorter and more intensive than those of general ***,the transition patterns are different among research *** limitations:Our research is limited to publications retrieved from the Web of science and their citing patents indexed in ***.A limitation inherent with LDA analysis is in the manual interpretation and labeling of"topics".Practical implications:Our study provides good references for policy-makers on allocating scientific resources and regulating financial budgets to face challenges related to the transformative technology of ***/value:The LDA model here is applied to topic identification in the area of transformative researches for the first time,as exemplified on ***,the dataset of all citing patents in this area helps to provide a full picture to detect the knowledge transition between S&T.
In the study of the brain, there is a hypothesis that sparse coding is realized in information representation of external stimuli, which is experimentally confirmed for visual stimulus recently. However, unlike the sp...
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In Mongolia, the “Baganuur” lignite coal mine is one of the largest open-pit mines; however, the stability of its internal dump is very difficult to maintain, which hinders the mine’s normal operation and negativel...
In Mongolia, the “Baganuur” lignite coal mine is one of the largest open-pit mines; however, the stability of its internal dump is very difficult to maintain, which hinders the mine’s normal operation and negatively influences the economy. To solve this internal waste dump slope stability problem, we studied the use of rock materials’ inherent mechanical properties to conduct numerical modelling and analysis on improved internal waste dump parameters using Gaussian Elimination-based Rocscience RS2 software. Finite element methods were used to determine the factors that could impact the stability of an internal waste dump based on the properties of the rock. For this research, we investigated whether single- and multi-dumps impacted internal dump height and dip angle and covered the analytical approach used to determine safety factors. The internal dump capacity can be increased by around 1.9 times at a 50 m height and a 28° dip angle, according to the results of the numerical simulation models. This research offers an optimal strength reduction factor (SRF) at a height of 45 m and a dip angle of 28° in comparable situations. Numerical simulations show that dip angle changes impact internal dump slope stability more than dump height modifications.
Municipal solid waste incineration products of bottom ash(BA),fly ash(FA),and pickling sludge(PS),causing severe environ-mental pollution,were transformed into glass ceramic foams with the aid of CaCO3 as a pore-foami...
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Municipal solid waste incineration products of bottom ash(BA),fly ash(FA),and pickling sludge(PS),causing severe environ-mental pollution,were transformed into glass ceramic foams with the aid of CaCO3 as a pore-foaming agent during *** effect of the BA/FA mass ratio on the phase composition,pore morphology,pore size distribution,physical properties,and glass structure was investigated,with results showing that with the increase in the BA/FA ratio,the content of the glass phase,Si-O-Si,and Q3Si units decrease *** glass transmission temperature of the mixture was also *** combined,the glass viscosity decreases,causing bubble coalescence and uneven pore *** ceramic foams with uniform spherical pores are *** the content of BA,FA,and PS are 35wt%,45wt%,and 20wt%,respectively,contributing to high performance glass ceramic foams with a bulk density of 1.76 g/cm3,porosity of 56.01%,and compressive strength exceeding 16.23 *** versatile and low-cost approach provides new insight into synergistically recycling solid wastes.
Oral administration is the most simple, noninvasive, convenient treatment. With the increasing demands on thetargeted drug delivery, the traditional oral treatment now is facing some challenges: 1) biologics how toimp...
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Oral administration is the most simple, noninvasive, convenient treatment. With the increasing demands on thetargeted drug delivery, the traditional oral treatment now is facing some challenges: 1) biologics how toimplement the oral treatment and ensure the bioavailability is not lower than the subcutaneous injections;2)How to achieve targeted therapy of some drugs in the gastrointestinal tract? Based on these two issues, drugdelivery microrobots have shown great application prospect in oral drug delivery due to their characteristics offlexible locomotion or driven ability. Therefore, this paper summarizes various drug delivery microrobotsdeveloped in recent years and divides them into four categories according to different driving modes: magneticcontrolleddrug delivery microrobots, anchored drug delivery microrobots, self-propelled drug delivery microrobotsand biohybrid drug delivery microrobots. As oral drug delivery microrobots involve disciplines such asmaterials science, mechanical engineering, medicine, and controlsystems, this paper begins by introducing thegastrointestinal barriers that oral drug delivery must overcome. Subsequently, it provides an overview of typicalmaterials involved in the design process of oral drug delivery microrobots. To enhance readers’ understanding ofthe working principles and design process of oral drug delivery microrobots, we present a guideline for designingsuch microrobots. Furthermore, the current development status of various types of oral drug delivery microrobotsis reviewed, summarizing their respective advantages and limitations. Finally, considering the significantconcerns regarding safety and clinical translation, we discuss the challenges and prospections of clinical translationfor various oral drug delivery microrobots presented in this paper, providing corresponding suggestions foraddressing some existing challenges.
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