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Polymerization of pyrrole induced by pillararene functionalized graphene for supercapacitor electrode

Chinese Chemical Letters 2022年第11期33卷 4846-4849页

作者： Fang Guo Junqiang Guo Zhiqiang Zheng Tao Xia Aadil Nabi Chishti Liwei Lin Wang Zhang Guowang Diao School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China Department of Applied Bioengineering Graduate School of Convergence Science and TechnologySeoul National UniversitySuwon 443-270South Korea

Conducting polymer is an important electrode material for supercapacitors because of its high initial specific ***,a novel nanocomposite composed of polypyrrole(PPy)film homogeneously immobilized on the pillar[5]arene functionalized reduced graphene oxide nanosheets(RGO-HP5 A-PPy)was successfully ***-HP5 A induced pyrrole to polymerize on the graphene surface and the specific capacitance loss caused by PPy agglomeration was ***,the specific capacitance of RGOHP5 A-PPy was up to 495 F/g at 1 A/*** with pure PPy(319 F/g),the specific capacitance was increased by 55%.The specific capacitance retention of the assembled symmetric supercapacitor reached76%after 10,000 cycles at 5 A/*** study gave full play to the advantages of pillar[5]arene,graphene and PPy,and was expected to promote the development of supramolecular functionalized composites in energy storage.

关键词： Nanocomposite Pillar[5]arene Graphene Polypyrrole Supercapacitor

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STORM Imaging Buffer with Immersion Oil Refractive Index 16

STORM Imaging Buffer with Immersion Oil Refractive Index

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16th Pacific Rim Conference on Lasers and Electro-Optics, CLEO-PR 2024

作者： Lee, Youngseop Lee, Yeunho Lee, Minchol Koo, Donghoon Kim, Dongwoo Kim, Hongrae Lee, Kangwon Kim, Jeongmin Seoul National University Department of Chemistry Seoul08826 Korea Republic of Graduate School of Convergence Science and Technology Seoul National University Department of Applied Bioengineering Seoul08826 Korea Republic of Research Institute for Convergence Science Seoul National University Seoul08826 Korea Republic of

STORM imaging buffer matching standard immersion oil's refractive index, offering enhanced temporal stability and dye versatility for multi-color imaging, while maintaining comparable performance to traditional wa...

ISBN: (纸本)9798350372076

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Imaging Buffer For STORM With Standard Immersion Oil Refractive Index

Imaging Buffer For STORM With Standard Immersion Oil Refract...

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2024 Conference on Lasers and Electro-Optics/Pacific Rim, CLEO-PR 2024

作者： Lee, Youngseop Lee, Yeunho Lee, Minchol Koo, Donghoon Kim, Dongwoo Kim, Hongrae Lee, Kangwon Kim, Jeongmin Department of Applied Bioengineering Graduate School of Convergence Science and Technology Seoul National University Seoul08826 Korea Republic of Department of Chemistry Seoul National University Seoul08826 Korea Republic of Research Institute for Convergence Science Seoul National University Seoul08826 Korea Republic of

关键词： Refractive index

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A micro-fragmented collagen gel as a cell-assembling platform for critical limb ischemia repair

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Bioactive Materials 2024年第4期34卷 80-97页

作者： Haeun Chung Jung-Kyun Choi Changgi Hong Youngseop Lee Ki Hyun Hong Seung Ja Oh Jeongmin Kim Soo-Chang Song Jong-Wan Kim Sang-Heon Kim Center for Biomaterials Biomedical Research InstituteKorea Institute of Science and Technology(KIST)Seoul02792Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolUniversity of Science and TechnologySeoul02792Republic of Korea Department of Applied Bioengineering Graduate School of Convergence Science and TechnologySeoul National UniversitySeoul08826Republic of Korea Research Institute for Convergence Science Seoul National UniversitySeoul08826Republic of Korea Department of Genetics and Biotechnology College of Life SciencesKyung Hee UniversityYongin-siGyeonggi-do17104Republic of Korea S.Biomedics Co. Ltd.Seoul04797Republic of Korea

Critical limb ischemia(CLI)is a devastating disease characterized by the progressive blockage of blood *** the paracrine effect of growth factors in stem cell therapy made it a promising angiogenic therapy for CLI,poor cell survival in the harsh ischemic microenvironment limited its ***,an imperative need exists for a stem-cell delivery method that enhances cell ***,a collagen microgel(CMG)cell-delivery scaffold(40×20μm)was fabricated via micro-fragmentation from collagen-hyaluronic acid polyionic complex to improve transplantation *** human adipose-derived stem cells(hASCs)with CMG enabled integrin receptors to interact with CMG to form injectable 3-dimensional constructs(CMG-hASCs)with a microporous microarchitecture and enhanced mass ***-hASCs exhibited higher cell survival(p<0.0001)and angiogenic potential in tube formation and aortic ring angiogenesis assays than cell *** of CMG-hASCs intramuscularly into CLI mice increased blood perfusion and limb salvage ratios by 40%and 60%,respectively,compared to cell aggregate-treated *** immunofluorescent analysis revealed that transplanted CMG-hASCs have greater muscle regenerative and angiogenic potential,with enhanced cell survival than cell aggregates(p<0.05).Collectively,we propose CMG as a cell-assembling platform and CMG-hASCs as promising therapeutics to treat CLI.

关键词： Regenerative medicine Stem cell therapy Collagen microgel 3D cell culture Critical limb ischemia

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Line Spectral Reflectometry for High-Speed, Large-Area Thickness Measurement 16

Line Spectral Reflectometry for High-Speed, Large-Area Thick...

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16th Pacific Rim Conference on Lasers and Electro-Optics, CLEO-PR 2024

作者： Lee, Minchol Park, Jaehyun Kim, Jeongmin Korea Institute of Industrial Technology Smart Manufacturing System R&d Department Cheonan31056 Korea Republic of Seoul National University Department of Applied Bioengineering Graduate School of Convergence Science and Technology Seoul08826 Korea Republic of Research Institute for Convergence Science Seoul National University Seoul08826 Korea Republic of

Introducing Line Spectroscopic Reflectometry (LSR) for rapid thickness measurement over large optically transparent layers. LSR extends point measurement to lines, boosting speed by 2000 times and demonstrating inline... 详细信息

ISBN: (纸本)9798350372076

关键词： Thickness measurement

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Particle morphology control for spherical powder fabrication using the ball milling process with DEM simulation

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Particuology 2024年第7期90卷 41-50页

作者： Battsetseg Jargalsaikhan Khulan Uranchimeg Amgalan Bor Kyung Sung Kim Heekyu Choi Research Institute of Future Convergence Changwon National UniversityChangwonGyoungnam 641-773Republic of Korea Graduate School of Material Science Engineering Changwon National UniversityChangwonGyoungnam 641-773Republic of Korea Department of Chemical and Biological Engineering School of Engineering and Applied SciencesNational University of MongoliaUlaanbaatar 14200Mongolia Department of Mechatronics Convergence Engineering College of Future ConvergenceChangwon National UniversityChangwonGyoungnam 641-773Republic of Korea Graduate School of Convergence on Culture Technology Changwon National UniversityChangwonGyoungnam 641-773Republic of Korea

Characteristics of spherical particles on copper powder and changing sizes were studied in a ball mill under various experimental conditions,such as different ball diameters,high rotation speeds,and milling times,using a discrete element method(DEM)*** experiment has investigated the characteristics of spherical particle morphology evolution involved in the mechanical alloying of copper *** morphological evolution of the copper particle was analyzed using scanning electron microscopy(SEM).A spherical copper particle was shown with a roundness value using imageJ *** DEM was used to simulate the ball motion in a planetary ball mill,and the impact energy and shear energy generated during the collision were analyzed to estimate the contact number between the ball and the ball ***,as the size of the ball decreased,the number of ball-to-ball and ball-to-wall contacts increased accordingly,and the spherical shape of the copper powder changed.

关键词： Planetary ball mill DEM simulation Spherical particle morphology Copper powder Ball diameter

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Design Strategy for Vulcanization Accelerator of Diphenylguanidine/Cyclodextrin Inclusion Complex for Natural Rubber Latex Foam with Enhancing Performance

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Research 2023年第1期2022卷 97-109页

作者： Wang Zhang Liwei Lin Junqiang Guo Ming Wu Sumin Park Hang Yao Sun Ha Paek Guowang Diao Yuanzhe Piao Department of Applied Bioengineering Graduate School of Convergence Science and Technology Seoul National UniversitySeoul 08826Republic of Korea School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhouJiangsu 225002China Departmentof Neurosurgery Movement Diorder CenterSeoul National University HospitalHypoxia Ischemia Disease InstituteCancer Research InstituteSeoul National University College of MedicineSeoul 03080Republic of Korea Advanced Institutes of Convergence Technology 145 Gwanggyo-roYeongtong-guSuwon-siGyeonggi-do16229Republic of Korea

Vulcanization is an essential process to obtain high-performance rubber ***(DPG)is often used as the secondary accelerator in the vulcanization process of natural rubber(NR)***,DPG would make NR latex emulsion exhibit gelation,resulting in the negative vulcanization *** addition,exposure to DPG might lead to some physiological diseases during the production process of DPG doped NR ***-β-cyclodextrin(HP-β-CD)with the hydrophobic interior and hydrophilic exterior has the advantages of good water solubility,high bioavailability,reliable stability,and low *** this study,the inclusion complex of diphenylguanidine-hydroxypropyl-β-cyclodextrin(DPG-HP-β-CD)is prepared by bali milling with a host-guest molar ratio of 1:1,which has also been applied to the foaming process of NR *** mechanical properties of DPG-HP-β-CD inclusion complex/natural rubber latex foam(DPG-HP-β-CD/NRLF)have been significantly improved,including the tensile strength,elongation at break,hardness,compression set,resilience,and antiaging ***,the usage of DPG has been reduced,leading to the reduction of toxicity and environmental hazards.

关键词： latex rubber Complex

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Study of a water-soluble supramolecular complex of curcumin andβ-cyclodextrin polymer with electrochemical property and potential anti-cancer activity

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Chinese Chemical Letters 2022年第8期33卷 4043-4047页

作者： Wang Zhang Ping Xiao Liwei Lin Fang Guo Qingyue Wang Yuanzhe Piao Guowang Diao School of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou 225002China Department of Applied Bioengineering Graduate School of Convergence Science and TechnologySeoul National UniversitySuwon 443-270Republic of Korea Shanghai Suni Biotechnology Development Co. Ltd.Shanghai 201300China Advanced Institutes of Convergence Technology Suwon 443-270Republic of Korea

As a member of the curcuminoid compound family,curcumin(Cur)has many interesting therapeutic ***,its low aqueous solubility and stability have resulted in poor bioavailability and restricted clinical *** on size matching,β-cyclodextrin polymer(β-CDP),with its hydrophilic polymer chains and hydrophobic cavities,can form an inclusion complex with *** improve the water solubility and stability of Cur,a simple and eco-friendly grinding method was designed to formβ-CDP inclusion *** to the Boltzmann-Hamel's method and Job's method,the molar ratio of theβ-CD unit inβ-CDP to Cur was determined to be 1:*** diffusion coefficient and diffusion activation energy of Cur-β-CDP were calculated in an electrochemical *** supramolecular complex worked well in vitro to inhibit the proliferation of hepatoma carcinoma cells ***,this method visibly reduced the undesirable side effects on normal cells,without weakening the anti-cancer activity of the *** expect that the obtained host-guest complex will provide a new approach for delivering natural drug molecules,having low water solubility.

关键词： Cyclodextrin polymer Curcumin Solubility Anti-cancer activity Supramolecular complex

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Aptamer-conjugated liposome system for targeting MUC1-positive cancer: an in silico screening approach

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Health Nanotechnology 2025年第1期1卷 1-14页

作者： Khan, Md Shakil Ahmed Park, Jiwoo Lee, Somin Hwang, Jee-Eun Oh, Chiwoo Kim, MinKyu Lee, Jeong-Seob Jeon, Jongyeong Park, Beomjin Li, Shengjun Jung, Han Na Im, Hyung-Jun Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology Seoul National University Seoul Republic of Korea Department of Applied Bioengineering Graduate School of Convergence Science and Technology Seoul National University Seoul Republic of Korea Cancer Research Institute Seoul National University Seoul Republic of Korea Research Institute for Convergence Science Seoul National University Seoul Republic of Korea

This study aims to overcome the adverse effects of conventional cytotoxic chemotherapy on healthy organs by developing a target-specific approach utilizing Doxorubicin (DOX)-encapsulated liposome conjugated with aptamer which has high binding affinity to the overexpressed Mucin-1 (MUC1) protein in various cancer types. To ensure optimal aptamer selection, we conducted a comprehensive in silico comparison of several MUC1-targeting aptamers, including 5TR1, MA3, S1.6, S2.2, and STRG2. As a results, the S1.6 aptamer was selected as a targeting ligand by comparing the thermodynamic stability, docking score, confidence score, and binding affinity. Also, spectrophotometer, gel electrophoresis, and Dynamic light scattering (DLS) confirm the size, zeta potential, DOX encapsulation rate, stability, and aptamer conjugation of liposomes. In addition, flow cytometry results validate MUC1 expression in MCF7 cells while not in MDA-MB-231 cells, while confocal microscopy confirmed the specific cellular uptake of the lipo-aptamer complex. Consequently, this aptamer-mediated liposomal drug delivery approach shows potential for enhancing the specificity and reducing the side effects of conventional chemotherapy, while the use of in silico methods provides an efficient and cost-effective strategy for screening and optimizing aptamer candidates, simplifying the overall development process. Further in vivo evaluation for therapeutic efficacy and clinical applications is warranted.

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Advanced flexible humidity sensors:structures,techniques,mechanisms and performances

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Frontiers of Materials science 2023年第4期17卷 37-53页

作者： Yuzhe Zhang Yuxi Liu Lifei Lin Man Zhou Wang Zhang Liwei Lin Zhongyu Li Yuanzhe Piao Sun Ha Paek School of Environmental Science and Engineering Changzhou UniversityChangzhou 213164China Department of Applied Bioengineering Graduate School of Convergence Science and TechnologySeoul National UniversitySeoul 08826Republic of Korea Jiangsu Key Laboratory of Advanced Catalytic Materials and Technology School of Petrochemical EngineeringChangzhou UniversityChangzhou 213164China College of Chemistry and Molecular Sciences Wuhan UniversityWuhan 430072China Department of Neurosurgery Movement Disorder CenterSeoul National University HospitalSeoul 03080Republic of Korea Advanced Institutes of Convergence Technology Suwon-siGyeonggi-do 16229Republic of Korea

Flexible humidity sensors are widely used in many fields,such as environmental monitoring,agricultural soil moisture content determination,food quality monitoring and healthcare ***,it is essential to measure humidity accurately and reliably in different *** materials have been the focusing substrates of humidity sensors because of their rich surface chemical properties and structural *** addition,flexible materials have superior ductility for different *** this review,we have summarized several sensing mechanisms,processing techniques,sensing layers and substrates for specific humidity sensing ***,we have sorted out some cases of flexible humidity sensors based on different functional *** hope this paper can contribute to the development of flexible humidity sensors in the future.

关键词： flexible composite manufacturing technology sensing mechanism humidity sensor

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