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Human genome meeting 2016 : Houston, TX, USA. 28 February - 2 March 2016

Human genomics 2016年第1期10 Suppl 1卷 12页

作者： A. K. Srivastava Y. Wang R. Huang C. Skinner T. Thompson L. Pollard T. Wood F. Luo R. Stevenson R. Polimanti J. Gelernter X. Lin I. Y. Lim Y. Wu A. L. Teh L. Chen I. M. Aris S. E. Soh M. T. Tint J. L. MacIsaac F. Yap K. Kwek S. M. Saw M. S. Kobor M. J. Meaney K. M. Godfrey Y. S. Chong J. D. Holbrook Y. S. Lee P. D. Gluckman N. Karnani A. Kapoor D. Lee A. Chakravarti C. Maercker F. Graf M. Boutros G. Stamoulis F. Santoni P. Makrythanasis A. Letourneau M. Guipponi N. Panousis M. Garieri P. Ribaux E. Falconnet C. Borel S. E. Antonarakis S. Kumar J. Curran J. Blangero S. Chatterjee J. Akiyama D. Auer C. Berrios L. Pennacchio T. R. Donti G. Cappuccio M. Miller P. Atwal A. Kennedy A. Cardon C. Bacino L. Emrick J. Hertecant F. Baumer B. Porter M. Bainbridge P. Bonnen B. Graham R. Sutton Q. Sun S. Elsea Z. Hu P. Wang Y. Zhu J. Zhao M. Xiong David A. Bennett A. Hidalgo-Miranda S. Romero-Cordoba S. Rodriguez-Cuevas R. Rebollar-Vega E. Tagliabue M. Iorio E. D’Ippolito S. Baroni B. Kaczkowski Y. Tanaka H. Kawaji A. Sandelin R. Andersson M. Itoh T. Lassmann Y. Hayashizaki P. Carninci A. R. R. Forrest C. A. Semple E. A. Rosenthal B. Shirts L. Amendola C. Gallego M. Horike-Pyne A. Burt P. Robertson P. Beyers C. Nefcy D. Veenstra F. Hisama R. Bennett M. Dorschner D. Nickerson J. Smith K. Patterson D. Crosslin R. Nassir N. Zubair T. Harrison U. Peters G. Jarvik F. Menghi K. Inaki X. Woo P. Kumar K. Grzeda A. Malhotra H. Kim D. Ucar P. Shreckengast K. Karuturi J. Keck J. Chuang E. T. Liu B. Ji A. Tyler G. Ananda G. Carter H. Nikbakht M. Montagne M. Zeinieh A. Harutyunyan M. Mcconechy N. Jabado P. Lavigne J. Majewski J. B. Goldstein M. Overman G. Varadhachary R. Shroff R. Wolff M. Javle A. Futreal D. Fogelman L. Bravo W. Fajardo H. Gomez C. Castaneda C. Rolfo J. A. Pinto K. C. Akdemir L. Chin S. Patterson C. Statz S. Mockus S. N. Nikolaev X. I. Bonilla L. Parmentier B. King F. Bezrukov G. Kaya V. Zoete V. Seplyarskiy H. Sharpe T. McKee K. Popadin N. Basset-Seguin R. Ben Chaabene M. Andrianova C. Verdan K. Grosdemange O. Sumara M. E JCSRI Greenwood Genetic Center Greenwood USA School of Computing Clemson University Clemson USA Biochemical Genetics Laboratory Greenwood Genetic Center Greenwood USA Department Psychiatry Yale Sch Med and VA CT Healthcare Center West Haven USA Department Genetics Yale Sch Med and VA CT Healthcare Center West Haven USA Department Neurobiology Yale Sch Med and VA CT Healthcare Center West Haven USA Singapore Institute for Clinical Sciences Singapore Singapore National University of Singapore Singapore Singapore University of British Columbia Vancouver Canada KK Women’s and Children’s Hospital Singapore Singapore University of Southampton and University Hospital Southampton NHS Foundation Trust Southampton UK University of Auckland Auckland New Zealand McKusick-Nathans Institute of Genetic Medicine Johns Hopkins University School of Medicine Baltimore USA Esslingen University of Applied Sciences Esslingen Germany German Cancer Research Center Heidelberg Germany Department of Genetic Medicine and Development University of Geneva Medical School Geneva Switzerland Geneva University Hospitals-HUG Service of Genetic Medicine Geneva Switzerland GE3 Institute of Genetics and Genomics of Geneva University of Geneva Medical School Geneva Switzerland South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Edinburg USA South Texas Diabetes and Obesity Institute School of Medicine University of Texas Rio-Grande Valley Brownsville USA Institute of Genetic Medicine Johns Hopkins University Baltimore USA Genomics Division Lawrence Berkeley National Laboratory Berkeley USA Molecular and Human Genetics Baylor College of Medicine Houston USA Department of Translational Medical Sciences Federico II University Naples Italy Metabolon Inc Durham USA Section of Pediatric Neurology and Neuroscience Baylor College of Medicine Houston USA Tawam Hospital Abu Dhabi United Arab Emirates Stanford Medical School Stanford USA Sch

O1 The metabolomics approach to autism: identification of biomarkers for early detection of autism spectrum disorder A. K. Srivastava, Y. Wang, R. Huang, C. Skinner, T. Thompson, L. Pollard, T. Wood, F. Luo, R. Stevenson O2 Phenome-wide association study for smoking- and drinking-associated genes in 26,394 American women with African, Asian, European, and Hispanic descents R. Polimanti, J. Gelernter O3 Effects of prenatal environment, genotype and DNA methylation on birth weight and subsequent postnatal outcomes: findings from GUSTO, an Asian birth cohort X. Lin, I. Y. Lim, Y. Wu, A. L. Teh, L. Chen, I. M. Aris, S. E. Soh, M. T. Tint, J. L. MacIsaac, F. Yap, K. Kwek, S. M. Saw, M. S. Kobor, M. J. Meaney, K. M. Godfrey, Y. S. Chong, J. D. Holbrook, Y. S. Lee, P. D. Gluckman, N. Karnani, GUSTO study group O4 High-throughput identification of specific qt interval modulating enhancers at the SCN5A locus A. Kapoor, D. Lee, A. Chakravarti O5 Identification of extracellular matrix components inducing cancer cell migration in the supernatant of cultivated mesenchymal stem cells C. Maercker, F. Graf, M. Boutros O6 Single cell allele specific expression (ASE) IN T21 and common trisomies: a novel approach to understand DOWN syndrome and other aneuploidies G. Stamoulis, F. Santoni, P. Makrythanasis, A. Letourneau, M. Guipponi, N. Panousis, M. Garieri, P. Ribaux, E. Falconnet, C. Borel, S. E. Antonarakis O7 Role of microRNA in LCL to IPSC reprogramming S. Kumar, J. Curran, J. Blangero O8 Multiple enhancer variants disrupt gene regulatory network in Hirschsprung disease S. Chatterjee, A. Kapoor, J. Akiyama, D. Auer, C. Berrios, L. Pennacchio, A. Chakravarti O9 Metabolomic profiling for the diagnosis of neurometabolic disorders T. R. Donti, G. Cappuccio, M. Miller, P. Atwal, A. Kennedy, A. Cardon, C. Bacino, L. Emrick, J. Hertecant, F. Baumer, B. Porter, M. Bainbridge, P. Bonnen, B. Graham, R. Sutton, Q. Sun, S. Elsea O10 A novel causal methylation network approach to Alzheimer’s

关键词： Pulmonary Arterial Hypertension Oral Squamous Cell Carcinoma Deep Neural Network Autosomal Recessive Polycystic Kidney Disease Whole Genome Bisulfite Sequencing

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Inside Cover: Effect of the Nature of the CeO2Support of the Rh Catalyst on Triggering the Oxidative Reforming ofn-Butane for H2Production from Ambient Temperature (ChemCatChem 3/2014)

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ChemCatChem 2014年第3期6卷 666-666页

作者： Dr. Katsutoshi Sato Kouhei Adachi Prof. Dr. Yusaku Takita Dr. Katsutoshi Nagaoka Elements Strategy Initiative for Catalysts and Batteries (ESICB) Kyoto University 1-30 Goryo-Ohara Nishikyo-ku Kyoto 615-8245 (Japan) Department of Applied Chemistry Faculty of Engineering Oita University 700 Dannoharu Oita 870-1192 (Japan) Fax: (+81) 97-554-7979 Core Research for Evolutional Science and Technology (CREST) Japan Science and Technology Agency (JST) 7 Gobancho Chiyoda-ku Tokyo 102-0076 (Japan)

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Nanocycles of Materials' Transport studied by in-situ Electron Microscopy and Diffraction

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Journal of physics: Conference Series 2014年第1期522卷

作者： K Takayanagi Y Oshima S Lee T Tanaka Y Tanishiro Department of Physics Tokyo Institute of Technology 2-12-1-H-51 Oh-okayama Meguro-ku Tokyo 152-8551 Japan Core Research for Evolutional Science and Technology (CREST) Japan Science and Technology Agency (JST) K's Gobancho 7 Gobancho Chiyoda-ku Tokyo 102-0076 Japan Research center for ultra HVEM Osaka University 7-1 Mihokaoka Ibaraki 5670047 Japan Department of Materials Science & Engineering Tokyo Institute of Technology 2-12-1-H-51 Oh-okayama Meguro-ku Tokyo 152-8551 Japan

A sub-50pm resolution electron microscope was applied for in-situ studies of ion transport in lithium ion battery and CO-oxidation catalyst. Lithium ions in LiM2O4 electrodes (M: transition metals) and titanium ions in Au/TiO2 catalyst were enabled us to observe individually by ABF-STEM and TEM. Transport of lithium ions was seen, after in-situ observations, to induce structural transformation of the electrode materials that causes irreversible cycle of the battery reaction. Transport of the interstitial titanium ions results, due to oxygen gas for CO-oxidation, in modification of Au/TiO2 interface structure. In-situ studies, thus, revealed materials' transformation induced locally by ion/electron transport of the battery/catalyst system at high resolution and high contrast.

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Motion Capture and Manipulation of a Single Synthetic Molecular Rotor by Optical Microscopy†

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Angewandte Chemie 2014年第38期126卷

作者： Tomohiro Ikeda Takahiro Tsukahara Ryota Iino Masayuki Takeuchi Hiroyuki Noji Department of Applied Chemistry School of Engineering The University of Tokyo Bunkyo‐ku Tokyo 113‐8656 (Japan) Okazaki Institute for Integrative Bioscience Institute for Molecular Science National Institutes of Natural Sciences Higashiyama Myodaijicho Okazaki Aichi 444‐8787 (Japan) Organic Materials Group Polymer Materials Unit National Institute for Materials Science 1‐2‐1 Sengen Tsukuba Ibaraki 305‐0047 (Japan) Core Research for Evolutional Science and Technology (Japan) Science and Technology Agency Sanban‐cho Chiyoda‐ku Tokyo 102‐0075 (Japan)

Single‐molecule imaging and manipulation with optical microscopy have become essential methods for studying biomolecular machines; however, only few efforts have been directed towards synthetic molecular machines. Single‐molecule optical microscopy was now applied to a synthetic molecular rotor, a double‐decker porphyrin (DD). By attaching a magnetic bead (ca. 200 nm) to the DD, its rotational dynamics were captured with a time resolution of 0.5 ms. DD showed rotational diffusion with 90° steps, which is consistent with its four‐fold structural symmetry. Kinetic analysis revealed the first‐order kinetics of the 90° step with a rate constant of 2.8 s −1 . The barrier height of the rotational potential was estimated to be greater than 7.4 kJ mol −1 at 298 K. The DD was also forcibly rotated with magnetic tweezers, and again, four stable pausing angles that are separated by 90° were observed. These results demonstrate the potency of single‐molecule optical microscopy for the elucidation of elementary properties of synthetic molecular machines.

关键词： Einzelmoleküluntersuchungen Moleküldynamik Molekulare Maschinen Optische Mikroskopie Porphyrine

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Back Cover: Motion Capture and Manipulation of a Single Synthetic Molecular Rotor by Optical Microscopy (Angew. Chem. Int. Ed. 38/2014)

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Angewandte Chemie International Edition 2014年第38期53卷

作者： Dr. Tomohiro Ikeda Takahiro Tsukahara Prof. Ryota Iino Prof. Masayuki Takeuchi Prof. Hiroyuki Noji Department of Applied Chemistry School of Engineering The University of Tokyo Bunkyo-ku Tokyo 113-8656 (Japan) Okazaki Institute for Integrative Bioscience Institute for Molecular Science National Institutes of Natural Sciences Higashiyama Myodaijicho Okazaki Aichi 444-8787 (Japan) Organic Materials Group Polymer Materials Unit National Institute for Materials Science 1-2-1 Sengen Tsukuba Ibaraki 305-0047 (Japan) Core Research for Evolutional Science and Technology (Japan) Science and Technology Agency Sanban-cho Chiyoda-ku Tokyo 102-0075 (Japan)

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Rücktitelbild: Motion Capture and Manipulation of a Single Synthetic Molecular Rotor by Optical Microscopy (Angew. Chem. 38/2014)

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Angewandte Chemie 2014年第38期126卷

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Observation of Excitonic N-Body Bound States: Polyexcitons in Diamond

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Physical Review Letters 2013年第2期111卷 026402-026402页

作者： J. Omachi T. Suzuki K. Kato N. Naka K. Yoshioka M. Kuwata-Gonokami Photon Science Center The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-8656 Japan Core Research for Evolutional Science and Technology (CREST) JST 7-3-1 Hongo Bunkyo-ku Tokyo 113-8656 Japan Department of Applied Physics The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-8656 Japan Department of Physics Kyoto University Kitashirakawa Sakyo-ku Kyoto 606-8502 Japan Department of Physics The University of Tokyo 7-3-1 Hongo Bunkyo-ku Tokyo 113-0033 Japan

We have found a series of resonances associated with the bound state (polyexcitons, PENs) of N excitons up to N=6 in the emission spectra of diamond under two-photon excitation at around 10 K. Time-resolved spectra show a stepwise formation of PENs with smaller to larger N, as well as a successive decay from larger to smaller N. At higher excitation levels, the transformation of PENs into a condensed phase of electron-hole droplets occurs. The binding energies of the PENs, normalized to the exciton Rydberg energy, agree well with those of silicon, suggesting the universality of the phenomena.

关键词： Excitons

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High-field magnetism of the s=5/2 kagome-lattice antiferromagnet KFe 3(OH)6(SO4)2 for the magnetic field in the Kagome-plane

High-field magnetism of the s=5/2 kagome-lattice antiferroma...

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作者： Fujita, T. Hagiwara, M. Yamaguchi, H. Kimura, S. Kashiwagi, T. Matan, K. Nocera, D.G. Lee, Y.S. Grohol, D. KYOKUGEN Osaka University 1-3 Machikaneyama Toyonaka Osaka 560-8531 Japan College of Integrated Arts and Science Osaka Prefecture University Sakai Osaka 599-8531 Japan Institute for Materials Research Tohoku University 2-1-1 Katahira Sendai 980-8577 Japan Institute for Materials Science Graduate School of Pure and Applied Sciences University of Tsukuba 1-1-1 Tennodai Tsukuba Ibaraki 305-8573 Japan Department of Physics Mahidol University 272 Rama VI Road Ratchathewi Bangkok 10400 Thailand Department of Chemistry Massachusetts Institute of Technology Cambridge MA 02139 United States Department of Physics Massachusetts Institute of Technology Cambridge MA 02139 United States Dow Chemical Company Core RandD Midland MI 48674 United States

We have performed electron spin resonance (ESR) and magnetization measurements on single crystals of K-Fe-jarosite along the a-axis (in the kagome-plane). We have calculated the resonance branches and the magnetization curve using a spin Hamiltonian including the interlayer exchange and the Dzyaloshinsky-Moriya (DM) interactions. By putting the same parameter values for the analyses along the c-axis (normal to the kagome plane), the calculated results show satisfactory agreement with the experimental ones. As a result, we have successfully explained all the experimental results with one set of the intra- and the inter-plane exchange and the DM interaction parameters. © 2012 Springer science+Business Media New York.

关键词： Magnetization

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Hierarchical TIO2 brush type nanostructures for efficient photoelectrochemical water splitting

Hierarchical TIO2 brush type nanostructures for efficient ph...

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16th International Conference on Miniaturized Systems for Chemistry and Life sciences, MicroTAS 2012

作者： Pihosh, Yuriy Mawatari, Kazuma Turkevych, Ivan Le, Thu.H.H. Kajita, Yasuhito Chinen, Hiroyuki Tosa, Masahiro Kitamori, Takehiko Department of Applied Chemistry University of Tokyo Japan Core Research for Evolutional Science and Technology Japan Science and Technology Agency Japan Research Center of Photovoltaics National Institute of Advanced Industrial Science and Technology Japan Innovative Tribomaterials Group National Institute for Materials Science Japan

ISBN: (纸本)9780979806452

In this work, we developed a new type of nanostructured photoanode for a photoelectrochemical water splitting. The photoanode is based on hierarchical brush Titanium dioxide (TIO2) nanostructures (BTNs), which were fabricated by our recently reported Glancing Angle Deposition and Oxidation (GLADOX) technique. The maximum incident photon-to-current efficiency (IPCE) of the BTNs photoanode was around 22% in the UV region and around 5% in the VIS light. The integral IPCE of the BTNs measured under bias of 0.5V under UV light illumination was 30 times higher compared to the photoanode based on TIO 2 nanorods and about 200 times higher compared to the one based on TIO2 flat film. These results demonstrate that the brush TIO 2 nanostructures is a promising material for effective hydrogen generation via photocatalytic water splitting.

关键词： Fuel cells

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Direct Observation of Interstitial Titanium Ions in the CO Oxidation Model Catalyst Au/TiO2

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Microscopy and Microanalysis 2012年第S2期18卷 1300-1301页

作者： Tanaka, Takayuki Kunio, Takayanagi Sumiya, Amit Department of Physics Tokyo Institute of Technology Tokyo 152-8551 2-12-1-H-51 Oh-okayama Meguro-ku Japan Department of Materials Science & Engineering Tokyo Institute of Technology Japan Core Research for Evolutional Science and Technology (CREST) Japan Science and Technology Agency Tokyo 102-0076 K’s Gobancho 7 Gobancho Chiyoda-ku Japan

Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.

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