Modelling and predicting the effective behavior of non-ageing viscoelastic composites have attracted the attention of many researchers. Actually, predicting the effective behavior and the macroscopic overall response ...
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Three-dimensional objects can be scanned by 3D laser scanners that use active triangulation. These scanners create three-dimensional point clouds from the scanned objects. The laser line is identified in the images, w...
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We address efficient modeling of the intracellular action of a drug binding to the nuclear pregnane X receptor. The binded complex enters the cell nucleus and acts on DNA, resulting in enhanced production of an enzyme...
We address efficient modeling of the intracellular action of a drug binding to the nuclear pregnane X receptor. The binded complex enters the cell nucleus and acts on DNA, resulting in enhanced production of an enzyme which metabolizes, among others, co-administered drugs. Pharmacodynamic modeling is traditionally based on a compartmental approach, which simplifies the complex processes in the human body through the definition of a small number of compartments representing organs, tissues, cells, cytoplasm or abstract units. Inside a compartment, the concentrations of all substances are assumed to be distributed homogeneously, i.e. there is no spatial dependence. They lead to a system of ODEs for the time-dependence of the concentrations of the active substances. We will present an extension of a model from the literature for the action of the tuberculose-drug Rifampicin. The extension consists of a first attempt to add spatial resolution for substances that are active in the cytoplasm. Spatial resolution can be benecifial to analyze important issues like, among others, local exceeding of toxic drug levels, delay of transport and drug-drug interactions. We address efficient solution of the linear systems arising when numerically integrating the resulting PDE's and consider some preconditioning techniques based on properties of the underlying biochemical network.
The present paper describes the challenges and preliminary results obtained during the design and implementation of a disassembly system for capacitors placed on printed circuits boards. This research is included in a...
The present paper describes the challenges and preliminary results obtained during the design and implementation of a disassembly system for capacitors placed on printed circuits boards. This research is included in an attempt to reduce the impact of the electronic waste. The proposed architecture includes a six axis multipurpose industrial robot, dedicated sensors and a custom built tool. An originally designed rotary tool, with a specific type of drill bit, was used to dismantle each capacitor on the board. A sensor triggers the tool for the drill rotation when the perforation is accomplished accordingly, so that the friction force is big enough to initiate the dismantling procedure. Using the rotation movement of the drill, at a calculated number of rotations, the capacitors are successfully dismantled from the printed circuits board. An artificial vision system composed from a stereo camera and an image-processing algorithm, provides data with regard to the position of each capacitor on the printed circuit board. A vacuum cleaner was integrated in the scheme to recover the capacitors after dismantling. The scheme design was perpetually optimized using dedicated simulation software. Also, preliminary results obtained on the physical system underline the potential advantages of the proposed approach.
The expanding capabilities of today's microcontrollers and other devices lead to an increased utilization of these technologies in diverse fields. The automation and issue of remote control of moving objects belon...
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Noise is one of the major national problems for decades. In the case of buildings, this concernment has become an issue when building structures are becoming lighter and lighter in weight. This approach does not only ...
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Measuring and providing efficiency of educational applications is a serious, open problem, which impacts the future of this expanding industry greatly. Reaching player engagement is a complex challenge, as it also dep...
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Time-optimal motion planning is one of the most essential problems in robotic theories. The presented direct transcription approach uses convex optimisation method to obtain a minimum-time control for robot manipulato...
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With today's growing focus on noise control issues and the emergence of sound quality as an important aspect of product design, acoustic material testing is becoming increasingly relevant to engineers, designers a...
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