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2024 Laser Applications to Chemical, Security and Environmental Analysis, LACSEA 2024 - Part of Optica Sensing Congress

作者： Chiang, Chang-Yue Chen, Chien-Hsing Wang, Chien-Tsung Wu, Chin-Wei Chiang, Hsing-Yu Graduate School of Engineering Science and Technology Interdisciplinary Program of Engineering National Yunlin University of Science and Technology Yunlin64002 Taiwan Department of Biomechatronics Engineering National Pingtung University of Science and Technology Pingtung91201 Taiwan Department of Chemical & Materials Engineering National Yunlin University of Science and Technology Yunlin64002 Taiwan

ISBN: (纸本)9781957171371

This work proposes a carboxyl-graphene-oxide-based fiber optic localized surface plasmon resonance biosensor which employed anti-Cardiac Troponin I (anti-cTnI) as the recognition element to detect the cTnI-protein in 10 min with a limit of detection (LOD) of 5.8 pM, which meets the acceptable LOD for clinical testing of 0.04 ng/mL. © Optica Publishing Group 2024, © 2024 The Author(s)

关键词： Surface plasmon resonance

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Entropy-Based Analysis of Electromyography Signal Complexity During Flexion of the Flexor Carpi Radialis Muscle Under Varied Load Conditions 4th

Entropy-Based Analysis of Electromyography Signal Complexity...

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4th International Conference on Electronics, biomedical engineering, and Health Informatics, ICEBEHI 2023

作者： Katherine Putra, Alfian Pramudita Kurniawan, Angeline Shane Istiqomah, Dezy Zahrotul Sholihah, Nisa’ul Al-Salehi, Khalid Ali Salem Ain, Khusnul Sapuan, Imam Andarini, Esti Biomedical Engineering Master Program Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya60115 Indonesia Biomedical Engineering Study program Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia Department of Physics Faculty of Science and Technology Universitas Airlangga Surabaya Indonesia School of Nursing Southern Medical University Guangdong Guangzhou510515 China

ISBN: (纸本)9789819714629

The motor impairments that stroke patients experience as a primary contributor to death and disability also impact their quality of life. Due to its characteristics as complex muscle signals, the Electromyograph (EMG) signal may be one of the markers in rehabilitation and a substitute that may be used to judge the success of rehabilitation. This study aims to analyze the complexity of EMG signals originating from the flexion of the flexor carpi radialis muscle with various weights indicating the rehabilitation state. It is important to monitor the progress of rehabilitation, and it can be done by using complexity analysis. The complexity of the EMG is examined in this work utilizing entropy measurement, namely Approximate Entropy (ApEn), Sample Entropy (SampEn), and Fuzzy Approximate Entropy (fApEn). We concentrated on the flexor carpi radialis muscle using flexion–extension exercises and varying the weight load. This study’s results indicate differences in the complexity of the EMG signal in the flexor carpi radialis when performing flexion–extension movements. Three differences showed a correlation based on the value of ApEN, SampEn, and fApEn. Complexity Analysis using fApEn showed the best correlation at R = 0.9966, which can be used to evaluate the rehabilitation process. The increase in weight was followed by the increase of the fApEn value, indicating that the value can be used to evaluate the rehabilitation process. The use of complexity analysis of EMG signal from flexion movement in flexor carpi radialis with various weights can be used to indicate the progress in the rehabilitation process. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.

关键词： Entropy

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Boosting overall water splitting by incorporating sulfur into NiFe(oxy)hydroxide

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Journal of Energy Chemistry 2022年第1期31卷 364-371,I0010页

作者： Chiho Kim Seong Hyun Kim Seunghun Lee Ilyeong Kwon Seong Hyun Kim Shinho kim Changgyu Seok Yoo Sei Park Yangdo Kim Department of Materials Science and Engineering Pusan National UniversityBusan 46241Republic of Korea BK21 Four Innovative Graduate Education Program for Global High-tech Materials&PartsPusan National UniversityBusan 46241Republic of Korea Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH).Pohang 37673Republic of Korea

Developing highly active and cost-effective electrocatalysts for enhancing the hydrogen evolution reaction(HER)and oxygen evolution reaction(OER)is a significant challenge for overall water ***-incorporated nickel iron(oxy)hydroxide(S-NiFeOOH)nanosheets were directly grown on commercial nickel foam using a galvanic corrosion method and a hydrothermal *** incorporation of sulfur into NiFeOOH enhanced the catalytic activity for the HER and OER in 1 M KOH *** enhanced catalytic activity is attributed to the change in the local structure and chemical states due to the incorporation of *** performance for overall water splitting was achieved with an alkaline water *** was realized by employing S-NiFeOOH as a bifunctional electrocatalyst,thereby outperforming a water electrolyzer that requires the usage of precious metal electrocatalysts(i.e.,Pt/C as the HER electrocatalyst and IrO_(2) as the OER electrocatalyst).Moreover,when driven by a commercial silicon solar cell,an alkaline water electrolyzer that uses S-NiFeOOH as a bifunctional electrocatalyst generated hydrogen under natural *** study shows that S-NiFeOOH is a promising candidate for a large-scale industrial implementation of hydrogen production for overall water splitting because of its low cost,high activity,and *** addition,the solar-driven water electrolyzer using S-NiFeOOH as a bifunctional electrocatalyst affords the opportunity for developing effective and feasible solar power systems in the future.

关键词： Overall water splitting Hydrogen production Sulfur incorporated NiFe(oxy)hydroxide Electrocatalysts Solar-driven water splitting

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Ovalbumin-loaded paramagnetic nano-triangles for enhanced dendritic cell stimulation,T_(1)-MR imaging,and antitumor immunity

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Journal of materials science & Technology 2023年第17期148卷 123-137页

作者： Yike Hou Zhe Tang Jabeen Farheen Madiha Saeed Lijia Luo Wenzi Ren Dandan Luo Asim Mushtaq Ruibo Zhao Jian Ge Zhangsen Yu Yao Li M.Zubair Iqbal Xiangdong Kong Institute of Smart Biomedical Materials School of Materials Science and EngineeringZhejiang Sci-Tech UniversityHangzhou 310018China State Key Laboratory of Drug Research&Center of Pharmaceutics Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Cixi Institute of Biomedical Engineering CAS Key Laboratory of Magnetic Materials and DevicesKey Laboratory of Additive Manufacturing Materials of Zhejiang ProvinceNingbo Institute of Materials Technology and EngineeringChinese Academy of SciencesNingbo 315201China Department of Materials Imperial College LondonLondon SW72AZUK College of Life Sciences China Jiliang UniversityHangzhou 310018China Laboratory of Nanomedicine Medical Science Research CenterSchool of MedicineShaoxing UniversityShaoxing 312000China

Vaccine-based cancer immunotherapy has demonstrated a significant potential for cancer treatment in *** the efficiencies of vaccines are limited,they can be enhanced by a well-designed antigen delivery system that promotes sufficient antigen presentation of dendritic cells(DCs)for initiating high T cell ***,antigen-loaded manganese oxide(Mn_(3)O_(4))triangular-shaped ultrasmall nanoparti-cles were prepared to stimulate DC-based immunotherapy under the guidance of T_(1)magnetic resonance *** FDA-approved triblock copolymer Pluronic^(■)F-68 wasused not onlyto transferthe phase from hydrophobic to hydrophilic but also to enrich antigen loading and improve the biocompatibility of the prepared ***(OVA),a model antigen,was adsorbed on the surface of polymer-coated nanoparticles through electrostatic interaction to form Mn_(3)O_(4)@PF68-OVA nanoparticle-antigen complexes to stimulate DC-based immunization and antigen-specific T cell *** Mn_(3)O_(4)@PF68-OVA nanovaccine(NV)induces negligible toxicity effects against 4T1 and bone marrow-derived dendritic cells(BMDCs)by conventional methods supports the proliferation of intestine organoids,which are an innovative three-dimensional cytotoxicity evaluation system,thereby indicating their potential safety for in vivo cancer *** designed paramagnetic nanovaccine possessed excellent OVA delivery to dendritic-regulated antigen-specific T cells in vitro by stimulating the maturation level of *** ad-dition,Mn_(3)O_(4)@PF68-OVA NVs enhance immunity in vivo by increasing the T-cells and M1 macrophages,which suggests improved ***,vaccination with Mn_(3)O_(4)@PF68-OVA offer complete pro-tection in the prophylactic group and significant tumor inhibition in the therapeutic group against B16-OVA *** addition,the designed nanovaccine demonstrated high T_(1)-MR imaging in the tumor,fur-ther justifying enhanced tumor accumulation and capability to

关键词： Ovalbumin Nanovaccine Antigen delivery Magnetic resonance imaging Contrast agent Cancer immunotherapy

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Brain age estimation:premise,promise,and problems

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Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron Ji Hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

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Oxidating liquid metal interface integrated capacitive pressure detection

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science China(Technological sciences) 2023年第6期66卷 1629-1639页

作者： FU Jun-Heng ZHAN Fei XING ZeRong ZHANG Teng SUN XinLong ZENG Yun YAN MingLei TANG Wei LIU Jing WANG Lei ZHAO Yang College of Water Conservancy and Hydropower Engineering Sichuan Agricultural UniversityYa’an 625014China School of Electrical and Electronic Engineering Shijiazhuang Tiedao UniversityShijiazhuang 050043China Beijing Key Laboratory of Cryo-Biomedical Engineering Technical Institute of Physics and ChemistryChinese Academy of SciencesBeijing 100190China Department of Materials Science and Engineering The University of SheffieldSheffield S13JDUK School of Future Technology University of Chinese Academy of SciencesBeijing 100049China Department of Biomedical Engineering School of MedicineTsinghua UniversityBeijing 100084China

The characteristics of real-time monitoring and flexible integration based on passive capacitive detection are becoming the preferred sensing strategy for wearable ***,the currently designed capacitive sensors mostly focused on the bionic microstructures to improve sensitivity and measurement accuracy,while ignoring the inherent mechanical wear and resistance of multilayer *** this paper,an integrated monolithic capacitive pressure detection based on room temperature liquid metal is designed and fabricated,avoiding the tightness problem of the multi-layer *** oxidized paste-like liquid metal owning superior interfacial wetting properties can stably adhere to the surface of the porous *** gas-filled porous framework endows the capacitive sensor with a mechanical response of 0.0557 g with a response and recovery time of 1.26 and 0.63 s under a load condition of 150 Pa,and steadily maintained in 1600 cycle ***,the capacitive sensor is employed to detect human physiological signals and force shock responses,which could clearly distinguish different action signals,providing a new platform for the subsequent development and design of integrated capacitive sensors.

关键词： liquid metal interfacial wetting capacitive detection motion monitoring

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Effect of Surface Roughness on the Magnetism, Nano-indentation, Surface Energy, and Electrical Properties of Co60Fe20Dy20 Films on Si (100) Substrate

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Journal of Electronic materials 2024年第4期53卷 1752-1762页

作者： Liu, Wen-Jen Chang, Yung-Huang Chiang, Chia-Chin Chen, Yuan-Tsung Lin, Chih-Chien Chen, Pei-Ling Lin, Shih-Hung Department of Materials Science and Engineering I-Shou University Kaohsiung840 Taiwan Bachelor Program in Industrial Technology National Yunlin University of Science and Technology 123 University Road Section 3 Yunlin Douliou64002 Taiwan Department of Mechanical Engineering National Kaohsiung University of Science and Technology Kaohsiung City80778 Taiwan Graduate School of Materials Science National Yunlin University of Science and Technology 123 University Road Section 3 Yunlin Douliou64002 Taiwan Department of Electronic Engineering National Yunlin University of Science and Technology 123 University Road Section 3 Yunlin Douliou64002 Taiwan

In this study, we focused on depositing a target material, cobalt-iron-dysprosium (Co60Fe20Dy20), onto silicon (Si) (100) substrates with thickness varying from 10 nm to 50 nm through a direct-current (DC) magnetron sputtering technique. The subsequent step involved subjecting the samples to an hour-long annealing process in a vacuum annealing furnace at temperatures of 100°C, 200°C, and 300°C. To assess the elemental composition of the CoFeDy films, energy-dispersive X-ray spectroscopy (EDS) was employed. An observed trend indicated an increase in low-frequency alternating-current magnetic susceptibility (χac) with the increasing thickness. Remarkably, the CoFeDy films exhibited their peak χac following annealing at 300°C, with an optimal resonance frequency of 50 Hz. After annealing at 300°C, the CoFeDy film’s surface energy peaked at 50 nm. The magnetic, electrical, and adhesive properties of the CoFeDy films were notably influenced by surface roughness at different annealing temperatures. Atomic force microscopy (AFM) analysis revealed a gradual reduction in film roughness post-annealing, corresponding to smoother surfaces indicative of a weaker domain wall pinning effect, heightened carrier conductivity, and increased liquid spreading. Collectively, these outcomes contributed to diminished χac, reduced electrical resistance, and enhanced adhesion. Graphical Abstract: (Figure presented.) © The Minerals, Metals & materials Society 2024.

关键词： Adhesion

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Hydrogels for ameliorating osteoarthritis:Mechanical modulation,anti-inflammation,and regeneration

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BMEMat(biomedical engineering materials) 2024年第2期2卷 34-60页

作者： Xuwei Jiang Yuxiang Sun Yuanning Lyu Heemin Kang Jianyang Zhao Kunyu Zhang Liming Bian School of Biomedical Sciences and Engineering South China University of TechnologyGuangzhou International CampusGuangzhouChina National Engineering Research Center for Tissue Restoration and Reconstruction South China University of TechnologyGuangzhouChina Guangdong Provincial Key Laboratory of Biomedical Engineering South China University of TechnologyGuangzhouChina Key Laboratory of Biomedical Materials and Engineering of the Ministry of Education South China University of TechnologyGuangzhouChina Department of Materials Science and Engineering Korea UniversitySeoulRepublic of Korea

Osteoarthritis(OA)is a chronic and degenerative disease with limited clinical options for effective ***,significant endeavors have been explored to reveal its pathogenesis and develop treatments against ***,designed with a striking resemblance to the extracellular matrix,offer a biomimetic interaction with biological tissues,presenting a promising avenue for OA *** a result,biocompatible hydrogels have been erected incorporating on-demand bioactivities to optimize the intra-articular microenvironment,thereby alleviating OA symptoms and fostering the eventual regeneration of articular *** review highlights the collaborative objectives underlying the establishment of this tissue microenvironment,encompassing mechanical modulation,anti-inflammation,and tissue ***,we consolidate recent advances in hydrogel-based biomaterials,serving as the tissue engineering scaffolds to replicate the lubrication properties of natural joints or the bioactive agent-loaded vehicles to combat localized ***,hydrogels function as cell scaffolds to facilitate the maintenance of cellular homeostasis and contribute to the advancement of cartilage ***,this review outlines the prospective directions for hydrogel-mediated OA therapies.

关键词： cargo-delivery cellular induction hydrogels lubrication osteoarthritis

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Development of a Smart Guidewire for Intravascular Sensing 9th

Development of a Smart Guidewire for Intravascular Sensing

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9th International Conference on the Development of biomedical engineering in Vietnam, BME 2022

作者： Dong, Chao-Wei Joo, Dong-Hyun Moon, Ki-Jeong Yoon, Se-Yeon Nguyen, Hua Quang Huy Park, Woo-Tae Department of Mechanical Engineering Seoul National University of Science and Technology Seoul01811 Korea Republic of Convergence Program of Biomedical Engineering and Biomaterials Seoul National University of Science and Technology Seoul01811 Korea Republic of

ISBN: (纸本)9783031446290

This study presents a smart guidewire developed to measure the pressure inside blood vessels during minimally invasive surgery. The use of pressure sensor guidewires enables the medical doctor to make a judgement of the stent insertion procedure by precisely measuring coronary pressure. A pressure sensor is embedded inside the guidewire to measure the coronary lesion's vascular pressure to determine the clogging's severity. Pressure sensors inside the guidewires require high sensitivity, good linearity, and huge size reduction. The pressure sensor needs to be packaged inside a 350 µm diameter catheter. Size constraints and mechanical reliability requirements are extremely high. We describe the design and manufacture of the micro-scaled pressure sensor and the packaging process of the guidewire. To improve sensor sensitivity and reduce nonlinearity, we employed a finite element analysis to optimize the design for the membrane. The sensor fabrication process employs a cavity-first process for ultrathin sensor design. Additionally, we built a measurement system that records the sensor signal in air pressure. The results showed that the air pressure ranged up to 7.2 psi. We developed a systematic setup for assembling the ultraminiature pressure sensor inside the 800 µm guidewire. The packaging procedure includes the preparation of the electric wires, sensor placement, sensor to wire alignment, soldering, and finally, wired sensor placement inside the medical tubing. © The Author(s), under exclusive license to Springer Nature Switzerland AG. 2024.

关键词： Pressure sensors

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An interpretable deep learning approach for designing nanoporous silicon nitride membranes with tunable mechanical properties

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npj Computational materials 2023年第1期9卷 1524-1533页

作者： Ali KShargh Niaz Abdolrahim Department of Mechanical Engineering University of RochesterRochesterNY 14627USA Materials Science program University of RochesterRochesterNY 14627USA Laboratory for Laser Energetics University of RochesterRochesterNY 14627USA

The high permeability and strong selectivity of nanoporous silicon nitride(NPN)membranes make them attractive in a broad range of *** their growing use,the strength of NPN membranes needs to be improved for further extending their biomedical *** this work,we implement a deep learning framework to design NPN membranes with improved or prescribed strength *** examine the predictions of our framework using physics-based *** results confirm that the proposed framework is not only able to predict the strength of NPN membranes with a wide range of microstructures,but also can design NPN membranes with prescribed or improved *** simulations further demonstrate that the microstructural heterogeneity that our framework suggests for the optimized design,lowers the stress concentration around the pores and leads to the strength improvement of NPN membranes as compared to conventional membranes with homogenous microstructures.

关键词： tunable prescribed strength

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