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Breathable,antifreezing,mechanically skin-like hydrogel textile wound dressings with dual antibacterial mechanisms

Bioactive materials 2023年第3期21卷 313-323页

作者： Sihan Jiang Jiajia Deng Yuhui Jin Bo Qian Wanqi Lv Qiangqiang Zhou Enhua Mei Rasoul Esmaeely Neisiany Yuehua Liu Zhengwei You Jie Pan Department of Orthodontics Shanghai Stomatological Hospital&School of StomatologyFudan UniversityShanghai200001PR China Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases Fudan UniversityShanghai200001PR China State Key Laboratory for Modification of Chemical Fibers and Polymer Materials College of Materials Science and EngineeringInstitute of Functional MaterialsResearch Base of Textile Materials for Flexible Electronics and Biomedical Applications(China Textile Engineering Society)Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative MedicineDonghua UniversityShanghai201620PR China Department of Endodontics Shanghai Stomatological Hospital&School of StomatologyFudan UniversityShanghai200001PR China Department of Materials and Polymer Engineering Faculty of EngineeringHakim Sabzevari UniversitySabzevar***Iran

Hydrogels are emerging as the most promising dressings due to their excellent biocompatibility,extracellular matrix mimicking structure,and drug loading ***,existing hydrogel dressings exhibit limited breathability,poor environmental adaptability,potential drug resistance,and limited drug options,which extremely restrict their therapeutic effect and working ***,the current research introduces the first paradigm of hydrogel textile dressings based on novel gelatin glycerin hydrogel(glyhydrogel)fibers fabricated by the Hofmeister effect based wet *** from the unique knitted structure,the textile dressing features excellent breathability(1800 times that of the commercially available 3 M dressing)and stretchability(535.51±38.66%).Furthermore,the glyhydrogel textile dressing can also withstand the extreme temperature of-80℃,showing the potential for application in subzero ***,the introduction of glycerin endows the textile dressing with remarkable antibacterial property and expands the selection of loaded drugs(e.g.,clindamycin).The prepared glyhydrogel textile dressing shows an excellent infected wound healing effect with a complete rat skin closure within 14 *** these functions have not been achievable by traditional hydrogel dressings and provide a new approach for the development of hydrogel dressings.

关键词： Hydrogel textile Hydrogel dressing Breathable Dual antibacterial Skin regeneration

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Automated analysis of fundus images for the diagnosis of retinal diseases: a review

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Research on biomedical engineering 2024年第1期40卷 225-251页

作者： Berto, Alexa Scarpa, Fabio Tsiknakis, Nikos Manikis, Georgios Fotiadis, Dimitrios I. Marias, Kostas Scarpa, Alberto D-Eye s.r.l. Padua Italy Department of Information Engineering University of Padova Padua35131 Italy Heraklion70013 Greece Department of Biomedical Research Institute of Molecular Biology and Biotechnology FORTH Ioannina45115 Greece Department of Materials Science and Engineering Unit of Medical Technology and Intelligent Information Systems University of Ioannina Ioannina45110 Greece Department of Electrical and Computer Engineering Hellenic Mediterranean University Heraklion71004 Greece

Purpose: Colour fundus images are widely used in diagnosis treatment decision of several retinal diseases such as diabetic retinopathy (DR), glaucoma and age-related macular degeneration (AMD). These very common conditions must be detected early and monitored to prevent progression and avoid permanent damage. Fundus images revealed to be useful also for the diagnosis of cataracts. In recent years, various automatic diagnostic support methods have been proposed in the literature, with the aim of facilitating widespread screening and obtaining quantitative, objective, and reproducible information. Methods: In this review paper, an overview of traditional, machine learning and modern deep learning techniques for ophthalmic disease diagnosis (i.e. glaucoma, DR, AMD, and cataract) using retinal fundus images is presented. In addition, various publicly available image datasets used for such purposes are described. Results: The current main challenges and findings are identified, as well as common aspects and discrepancies between the various methods developed for the various diseases. Conclusion: The overview of what has been done about all pathologies, rather than only on a specific one, could favour a migration of the best solutions and, hopefully, the development of a more precise and clinically useful automatic analysis of all pathologies. Important critical insights and research trends are also discussed. Graphical abstract: (Figure presented.) © The Author(s), under exclusive licence to The Brazilian Society of biomedical engineering 2023.

关键词： Pathology

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Potential application of graphene nanoplatelets as a high temperature lubricant for hot rolling

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Friction 2022年第11期10卷 1810-1823页

作者： Long WANG Anh Kiet TIEU Ming MA Jiaqing LI Guojuan HAI Hongtao ZHU State Key Laboratory of Solidification Processing Center of Advanced Lubrication and Seal MaterialsNorthwestern Polytechnical UniversityXi’an 710021China School of Mechanical MaterialsMechatronic and Biomedical EngineeringFaculty of Engineering and Information SciencesUniversity of WollongongNorthfields AvenueWollongongNSW 2522Australia State Key Laboratory of Tribology Department of Mechanical EngineeringTsinghua UniversityBeijing 100084China School of Materials Science and Engineering Shaanxi University of Science and TechnologyXi’an 710021China

Graphene has been shown to be a promising solid lubricant to reduce friction and wear of the sliding counterparts,and currently is reported to only function below 600℃.In this study,its potential as a lubricant above 600℃ was studied using a ball-on-disc tribo-meter and a rolling *** results suggest that a reduction up to 50%can be obtained with graphene nanoplatelets(GnP)under lubricated conditions between 600 and 700℃ when compared with dry *** this friction reduction can last more than 3 *** 800 and 900℃,the friction reduction is stable for 70 and 40 s,respectively,which indicates that GnP can potentially provide an effective lubrication for hot metal forming *** rolling experiments on steel strips indicate that GnP reduces the rolling force by 11%,7.4%,and 6.9%at 795,890,and 960℃,*** friction reductions are attributed to the easily sheared GnP between the rubbing interfaces.A temperature higher than 600℃ will lead to the gasification of the residual graphene on the strip surface,which is believed to reduce the black contamination from traditional graphite lubricant.

关键词： graphene high temperature lubricant hot rolling tribology properties

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Efficient Recycling of Magnesium Alloys via Partial Distillation Using Gravity-Multiple Effect Thermal System (G-METS)

Efficient Recycling of Magnesium Alloys via Partial Distilla...

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Magnesium Technology Symposium, 2025, held as part of the TMS Annual Meeting and Exhibition, TMS 2025

作者： McArthur Sehar, Daniel Saito, Kenichi Telgerafchi, Armaghan Gallego, Maya Sridhar, Meera Iurkovskyi, Artem Powell, Adam Department of Materials Science and Engineering Program Worcester Polytechnic Institute 100 Institute Rd. WorcesterMA01609 United States Department of Mechanical Engineering Shibaura Institute of Technology Tokyo Japan Department of Mechanical Engineering Worcester Polytechnic Institute WorcesterMA United States

ISBN: (纸本)9783031810602

MagnesiumMagnesium’s remarkable stiffnessStiffness-to-weight and high strengthStrength-to-weight ratios could enable substantial vehicle lightweighting versus aluminum and steel. However, primary production is very energy- and emissions-intensive, and recyclingRecycling cannot cost-effectively produce magnesiumMagnesium of sufficient purity for die casting and other structural applications. Distillation can produce high-purity magnesiumMagnesium but is capital- and energy-intensive. Gravity-Driven Multiple Effect Thermal System (G-METS) is a continuous low-pressure magnesiumMagnesium distillation process used in primary production or recyclingRecycling in which heat re-use leads to just 0.5–1 kWh energy consumption per kgMg Mg product—which is 80–90% less energy than current Mg distillation. This paper presents new partial distillation experiments showing 99.96% product purity. An industrial distiller design can help to estimate capital costs. New modeling work describes temperature and pressure change in the vapor conduit, energy use and losses in the industrial distiller, and effects of evaporator flow vanes on the separation of volatile elements such as zinc. © The Minerals, Metals & materials Society 2025.

关键词： Magnesium alloys

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Evaluation of temperature dependent vortex pinning properties in strongly pinned YBa_(2)Cu_(3)O_(7-δ)thin films with Y_(2)BaCuO_(5)nanoinclusions

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Superconductivity 2024年第1期9卷 95-105页

作者： Alok K.Jha Kaname Matsumoto Tomoya Horide Shrikant Saini Ataru Ichinose Paolo Mele Yutaka Yoshida Satoshi Awaji Department of Materials Science and Engineering Kyushu Institute of TechnologyTobata-kuKitakyushu 804-8550Japan Department of Mechanical and Control Engineering Kyushu Institute of TechnologyTobata-kuKitakyushu 804-8550Japan Central Research Institute of Electrical Power Industry YokosukaKanagawa 240-0196Japan College of Engineering-Innovative Global Program Shibaura Institute of TechnologyMinuma-kuSaitama 337-8570Japan Department of Energy Engineering and Science Nagoya UniversityChikusa-kuNagoya 464-8603Japan Institute for Materials Research Tohoku UniversityAoba-kuSendai 980-8577Japan

The pinning of quantized magnetic vortices in superconducting YBa_(2)Cu_(3)O_(7-δ)(YBCO or Y123)thin films with Y_(2)BaCuO_(5)(Y211)nanoinclusions have been investigated over wide temperature range(4.2-77 K).The concentration of Y211 nanoinclusions has been systematically varied inside YBCO thin films prepared by laser ablation technique using surface modified target *** pinning force density values(Fp∼0.5 TNm^(−3)at 4.2 K,9 T)have been observed for the YBCO film with moderate concentration of Y211 nanoinclusions(3.6 area%on ablation target).In addition,uniform enhancement in critical current density(J_(c))was observed in the angular dependent J_(c)measurement of YBCO+Y211 nanocomposite films.Y211 nanoinclusions have been found to be very efficient in pinning the quantized vortices thereby enhancing the in‐field J_(c)values over a wide range of *** the concentration of Y211 secondary phase into Y123 film matrix results into agglomeration of Y211 phase and observed as increased Y211 nanoparticle *** larger secondary phase nanoparticles are not as efficient pinning centers at lower temperatures as they are at higher temperatures due to substantial reduction of the coherence length at lower *** of the temperature dependence of J_(c)for YBCO+Y211 nanocomposite films has been conducted and possible vortex pinning mechanism in these nanocomposite films has been discussed.

关键词： YBCO thin film Critical current Vortex pinning Nanoscale APCs

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Numerical Modeling of C45 Steel to Predict the Temperature Ranges for Activation of Dynamic Strain Aging at Different Strain Rates 8th

Numerical Modeling of C45 Steel to Predict the Temperature R...

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8th International Conference on Manufacturing, Material and Metallurgical engineering, ICMMME 2024

作者： Hassan, Arhum Abed, Farid Materials Science and Engineering Program College of Arts and Sciences American University of Sharjah Sharjah26666 United Arab Emirates Department of Civil Engineering American University of Sharjah Sharjah26666 United Arab Emirates

ISBN: (纸本)9783031782947

This work predicts the temperature ranges for dynamic strain aging (DSA) activation in C45 steel at various strain rates through constitutive modeling and finite element (FE) simulations. DSA is often defined by a sudden increase in a metal’s strength when subjected to specific combinations of strain rates and temperatures due to the interaction of the diffused solute atoms with dislocations, and there is currently no effective constitutive model in the literature that can explain DSA physically. The current study offers a modification to the Voyiadjis–Abed (VA) model, which is used to predict DSA activation in C45 steel, in order to address this limitation. The modified constitutive model considers the diffusion kinetics and concentration of solute atom along the dislocation cores. The developed model was able to capture the activation of DSA in C45 steel at strain rates of 0.0015/s-0.15/s and temperature ranges of 500 K-750 K, which was found to be caused by carbon solute atoms. Additionally, FE simulations were carried out in ABAQUS through subroutine coded as VUMAT to validate the modified VA model’s prediction abilities. The results obtained compare effectively with the available experimental data. By integrating physical and microstructural features, the modified constitutive VA model can effectively capture the increase in flow stress due to the activation of DSA. This enables further investigation and progress in understanding the behavior of metals under specified temperature and strain rate conditions. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

关键词： Digital elevation model

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Regulating the proinflammatory response to composite biomaterials by targeting immunometabolism

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Bioactive materials 2024年第10期40卷 64-73页

作者： Chima V.Maduka Ashley V.Makela Anthony Tundo Evran Ural Katlin B.Stivers Maxwell M.Kuhnert Mohammed Alhaj Ehsanul Hoque Apu Nureddin Ashammakhi Kurt D.Hankenson Ramani Narayan Jennifer H.Elisseeff Christopher H.Contag Comparative Medicine&Integrative Biology Michigan State UniversityEast LansingMI48824USA Department of Biomedical Engineering College of EngineeringMichigan State UniversityEast LansingMI48824USA Institute for Quantitative Health Science&Engineering Michigan State UniversityEast LansingMI48824USA Translational Tissue Engineering Center Johns Hopkins University School of MedicineBaltimoreMD21231USA Department of Chemical Engineering&Materials Science Michigan State UniversityEast LansingMI48824USA Department of Biomedical Sciences College of Dental MedicineLincoln Memorial UniversityKnoxvilleTN37917USA Department of Orthopedic Surgery University of Michigan Medical SchoolAnn ArborMI48109USA Department of Biomedical Engineering Johns Hopkins University School of MedicineBaltimoreMD21231USA Department of Microbiology Genetics&ImmunologyMichigan State UniversityEast LansingMI48864USA BioFrontiers Institute University of ColoradoBoulderCO 80303USA.

Composite biomaterials comprising polylactide(PLA)and hydroxyapatite(HA)are applied in bone,cartilage and dental regenerative medicine,where HA confers osteoconductive ***,after surgical implantation,adverse immune responses to these composites can occur,which have been attributed to size and morphology of HA *** to effectively modulate these adverse immune responses have not been *** degradation products have been shown to alter immune cell metabolism(immunometabolism),which drives the inflammatory ***,to modulate the inflammatory response to composite biomaterials,inhibitors were incorporated into composites comprised of amorphous PLA(aPLA)and HA(aPLA+HA)to regulate glycolytic *** at specific steps in glycolysis reduced proinflammatory(CD86+CD206-)and increased pro-regenerative(CD206+)immune cell populations around implanted aPLA+***,neutrophil and dendritic cell(DC)numbers along with proinflammatory monocyte and macrophage populations were decreased,and Arginase 1 expression among DCs was *** immunometabolism to control the proinflammatory response to biomaterial composites,thereby creating a pro-regenerative microenvironment,is a significant advance in tissue engineering where immunomodulation enhances osseointegration and angiogenesis,which could lead to improved bone regeneration.

关键词： Hydroxyapatite Polylactide Immunometabolism Inflammation Regenerative medicine

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Unconventional assemblies of bisacylhydrazones:The role of water for circularly polarized luminescence

Aggregate

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Aggregate 2022年第5期3卷 185-193页

作者： Hye Jin Cho Dong Yeun Jeong Hwihyun Moon Taewoo Kim You Kyoung Chung Yeongdong Lee Zonghoon Lee Joonsuk Huh Youngmin You Changsik Song Department of Chemistry Sungkyunkwan UniversitySuwonGyeonggi 16419Republic of Korea Division of Chemical Engineering and Materials Science Graduate Program in System Health Science and EngineeringEwha Womans UniversitySeoul 03760Republic of Korea Center for Multidimensional Carbon Materials Institute for Basic Science(IBS)Department of Materials Science and EngineeringUlsan National Institute of Science and Technology(UNIST)Ulsan 44919Republic of Korea

Understanding the precise molecular arrangement of chiral supramolecular polymers is essential not only to comprehend complex superstructures like proteins and DNA but also for the development of next-generation optoelectronic materials,including materials displaying high-performance circularly polarized luminescence(CPL).Herein,we report the first chiral supramolecular polymer systems based on hydrazone–pyridinium conjugates comprising alkyl chains of different lengths,which afforded control of the apparent supramolecular *** supramolecular chirality is governed basically by the remote chiral centers of alkyl chains,helicity inversion was achieved by controlling the conditions under which the hydrazone building blocks underwent aggregation(i.e.,solvent compositions or temperature).More importantly,the addition of water to the system led to aggregationinduced hydrazone deprotonation,which resulted in a completely different selfassembly *** water molecules played an essential role,forming the assembly’s channel-like backbone,around which hydrazone molecules gathered as a result of hydrogen bonding *** co-assembly of an achiral hydrazone luminophore with the given supramolecular polymer system allowed the fabrication of a novel CPL-active hydrazone-based material exhibiting a high maximum value for the photoluminescence dissymmetry factor of -2.6×10^(-2).

关键词： circularly polarized luminescence(CPL) helicity control hydrazone self-assembly structural water supramolecular polymerization

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Liquid Transmission Electron Microscopy Imaging of Organic-inorganic Interfaces: Exploring Hydrated Collagen Mineralization Processes

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Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2023年第1期29卷 1236-1238页

作者： DiCecco, Liza-Anastasia Gao, Ruixin Gray, Jennifer L. Kelly, Deborah F. Sone, Eli D. Grandfield, Kathryn Department of Materials Science and Engineering McMaster University Hamilton ON Canada Department of Biomedical Engineering Pennsylvania State University University Park PA United States Materials Research Institute Pennsylvania State University University Park PA United States Institute of Biomedical Engineering University of Toronto Toronto ON Canada Center for Structural Oncology Pennsylvania State University University Park PAUSA Romania Faculty of Dentistry University of Toronto Toronto ON Canada Department of Materials Science and Engineering University of Toronto Toronto ON Canada School of Biomedical Engineering McMaster University Hamilton ON Canada

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Erosion-corrosion resistance of Mo-Ti- and Ni-Cr-Mo-alloyed medium-carbon martensitic steels: a critical analysis of synergistic effect of erosion and corrosion

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Journal of Iron and Steel Research International 2022年第8期29卷 1299-1311页

作者： De-fa Li Hang-yu Dong Cheng-yang Hu Kai-ming Wu Serhii Yershov Oleg Isayev School of Mechanical and Vehicle Engineering West Anhui UniversityLuan 237012AnhuiChina The State Key Laboratory of Refractories and Metallurgy Hubei Province Key Laboratory of Systems Science on Metallurgical ProcessingInternational Research Institute for Steel TechnologyWuhan University of Science and TechnologyWuhan 430081HubeiChina Laboratory for Excellence in Advanced Steel Research Materials Science and Engineering ProgramDepartment of MetallurgicalMaterials and Biomedical EngineeringUniversity of Texas at El PasoEl PasoTX 79968USA

Grain refinement renders Mo-Ti-alloyed medium-carbon martensitic steel to exhibit high hardness,high strength,and good toughness,but the erosion-corrosion resistance of steel in a corrosive slurry environment is not ***-Ti-alloyed medium-carbon martensitic steel is compared with Ni-Cr-Mo-alloyed medium-carbon martensitic steel,and the erosion-corrosion resistance of those two steels under impingement by NaCl solution with gravels has been *** components,pure-corrosion rate,pure-erosion rate,and synergistic effect of erosion and corrosion(SEEC)of erosion-corrosion rate,were *** pure-corrosion and pure-erosion rates of Mo-Ti-alloyed steel were higher than those of Ni-Cr-Mo-alloyed one;however,its erosion-corrosion rate was relatively lower because of a weak *** plastic deformation and work hardening due to gravel impingement were the essential reason for SEEC,which could be reduced by grain refinement,and consequently,Mo-Ti-alloyed steel with finer grains had better erosion-corrosion *** refinement could be an effective way to improve the erosion-corrosion resistance of martensitic steels.

关键词： Grain refinement Mo-Ti alloying Ni-Cr-Mo alloying Martensite Erosion-corrosion

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