Gene expression patterns of tumor cells can be inferred from features of circulating cell-free DNA(cfDNA),such as histone modifications and fragmentation patterns at ***,the direct relationship between cfDNA patterns ...
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Gene expression patterns of tumor cells can be inferred from features of circulating cell-free DNA(cfDNA),such as histone modifications and fragmentation patterns at ***,the direct relationship between cfDNA patterns and tumor-specific chromatin accessibility has not yet been experimentally established,limiting its current application to cancer diagnosis alone.
Plasmonic hybridization in a gold-silver alloy nanodisks array results in a pair of high and low energy LSPR modes. This high energy mode is applied for colorimetric detection of sub-nM and sub-monolayer biotin-strept...
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We report glucose sensing 10 mM to 0.1 mM in water using stamping surface-enhanced Raman spectroscopy (S-SERS) technique with nanoporous gold disk (NPGD) plasmonic substrates, a reagent- and separation-free technique....
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Transgender and gender nonconforming (TGnC) people are a primary target of the Trump administration. Multiple executive orders seek to erase TGnC protections; mandate denial of gender identity; and ban diversity, equi...
Transgender and gender nonconforming (TGnC) people are a primary target of the Trump administration. Multiple executive orders seek to erase TGnC protections; mandate denial of gender identity; and ban diversity, equity, and inclusion (DEI) (1). Changes to federal funding policies related to TGnC individuals and DEI threaten to curtail academic diversity and freedom (2). Institutions have been hesitant to resist, but for many TGnC scientists—especially TGnC individuals of color, immigrants, and those with disabilities—invisibility is not an option. Anticipatory obedience (3, 4), and even passive allyship, is insufficient; institutions must abandon neutrality and defend targeted communities to minimize further harm (5, 6). As queer and TGnC scientists, we call on researchers at all levels—from undergraduates to university presidents—to take direct, consistent, and rapid action.
Plasmonic arrays fabricated by low-cost nanosphere lithography feature disorderliness and corresponding non-uniform index sensitivity. A calibration technique based on hyperspectral imaging has been implemented to reg...
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Gold nanodisks array with minimal effect from the glass substrates have been fabricated using nanosphere lithography and HF undercutting. The undercut substrates have blueshifted plasmonic resonance with higher bulk r...
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Linear PEI (lPEI) has proven track record as an effective carrier for the delivery of therapeutic plasmid DNA (pDNA) for disease treatment. However, the lack of a reproducible method to produce pDNA/lPEI nanoparticles...
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