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Dynamic compliance penis enlargement patch

Bioactive materials 2024年第12期42卷 194-206页

作者： Rui Zheng Wenwen Zhong Muyuan Chai Xuetao Shi National Engineering Research Centre for Tissue Restoration and Reconstruction South China University of TechnologyGuangzhou510006PR China School of Materials Science and Engineering South China University of TechnologyGuangzhou510640PR China Department of Urology The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhou510655PR China Dongguan Key Laboratory of Smart Biomaterials and Regenerative Medicine The Tenth Affiliated HospitalSouthern Medical UniversityDongguan523000PR China Key Laboratory of Biomedical Engineering of Guangdong Province South China University of TechnologyGuangzhou510006PR China

Men are particularly sensitive to penis size,especially those with a deformed or injured *** can lead to a strong desire for penis enlargement *** the ethical sensitivities of the penis,penile implants need to be developed with both efficacy and *** this study,a polyvinyl alcohol(PVA)patch for penile enlargement prepared via cyclic freeze‒thaw cycles and alkaline *** PVA hydrogels treated with 5 M NaOH had the best mechanical properties and stability.A negative Poisson’s ratio structure is incorporated into the design of the enlargement patch,which allows it to conform well to the deformation of the *** rabbit models,the enlarged patches can effectively enlarge the penis without degradation or fibrosis while maintaining long-term stability in *** innovation not only provides a safe option for patients in need of penile enlargement but also promises to make a broader contribution to the field of dynamic tissue repair.

关键词： Polyvinyl alcohol Hydrogel Negative Poisson’s ratio Crystallization enhancement Penis enlargement

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Synthesis and characterization of chicken feather derived rachis fiber-bamboo particulate hybrid reinforced epoxy composites for sustainable structural applications

Journal of Responsible Production and Consumption

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Journal of Responsible Production and Consumption 2024年第1期1卷 1-17页

作者： Isiaka Oluwole Oladele Omoye Oseyomon Odemilin Samson Oluwagbenga Adelani Anuoluwapo Samuel Taiwo Olajesu Favor Olanrewaju Department of Metallurgical and Materials Engineering Federal University of Technology Akure Akure Nigeria and Department of Chemical and Mining Engineering University of Johannesburg Johannesburg South Africa Department of Metallurgical and Materials Engineering Federal University of Technology Akure Akure Nigeria Department of Materials Science and Engineering Program University of Colorado at Boulder Boulder Colorado USA Department of School of Aerospace Transport and Manufacturing School of Aerospace Transport and Manufacturing Cranfield University Cranfield UK Department of Materials Science and Engineering Iowa State University Ames Iowa USA

Purpose This paper aims to reduce waste management and generate wealth by investigating the novelty of combining chicken feather fiber and bamboo particles to produce hybrid biocomposites. This is part of responsible production and sustainability techniques for sustainable development goals. This study aims to broaden animal and plant fiber utilization in the sustainable production of epoxy resins for engineering applications. Design/methodology/approach This research used two reinforcing materials [chicken feather fiber (CFF) and bamboo particles (BP)] to reinforce epoxy resin. The BPs were kept constant at 6 Wt.%, while the CFF was varied within 3–15 Wt.% in the composites to make CFF-BP polymer-reinforced composite (CFF-BP PRC). The mechanical experiment showed a 21% reduction in densities, making the CFF-BP PRC an excellent choice for lightweight applications. Findings It was discovered that fabricated composites with 10 mm CFF length had improved properties compared with the 15 mm CFF length and pristine samples, which confirmed that short fibers are better at enhancing randomly dispersed fibers in the epoxy matrix. However, the ballistic properties of both samples matched. There is a 40% increase in tensile strength and a 54% increase in flexural strength of the CFF-BP PRC compared to the pristine sample. Originality/value According to the literature review, to the best of the authors’ knowledge, this is a novel study of chicken fiber and bamboo particles in reinforcing epoxy composite.

关键词： Green composite Sustainability Rachis fiber Bamboo particles Clean environment

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Vibrational EELS for Solid-State Li-Ion Batteries: Mapping Li Distributions and Beyond

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Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 2023年第1期29卷 633-635页

作者： Gadre, Chaitanya A. Lee, Tom Qi, Ji Ong, Shyue Ping Pan, Xiaoqing Department of Physics and Astronomy University of California Irvine CA United States Department of Materials Science and Engineering University of California Irvine CA United States Materials Science and Engineering Program University of California San Diego La Jolla CA United States Department of NanoEngineering University of California San Diego La Jolla CA United States Irvine Materials Research Institute University of California Irvine CA United States

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biomedical applications of magnetosomes: State of the art and perspectives

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Bioactive materials 2023年第10期28卷 27-49页

作者： Gang Ren Xia Zhou Ruimin Long Maobin Xie Ranjith Kumar Kankala Shibin Wang Yu Shrike Zhang Yuangang Liu Institute of Pharmaceutical Engineering Huaqiao UniversityXiamenFujian361021China College of Materials Science and Engineering Huaqiao UniversityXiamenFujian361021China College of Chemical Engineering Huaqiao UniversityXiamenFujian361021China Division of Engineering in Medicine Department of MedicineBrigham and Women’s HospitalHarvard Medical SchoolCambridgeMA02139USA The Sixth Affiliated Hospital of Guangzhou Medical University Qingyuan People’s HospitalSchool of Biomedical EngineeringGuangzhou Medical UniversityGuangzhou511436China Fujian Provincial Key Laboratory of Biochemical Technology XiamenFujian361021China

Magnetosomes, synthesized by magnetotactic bacteria (MTB), have been used in nano- and biotechnological applications, owing to their unique properties such as superparamagnetism, uniform size distribution, excellent bioavailability, and easily modifiable functional groups. In this review, we first discuss the mechanisms of magnetosome formation and describe various modification methods. Subsequently, we focus on presenting the biomedical advancements of bacterial magnetosomes in biomedical imaging, drug delivery, anticancer therapy, biosensor. Finally, we discuss future applications and challenges. This review summarizes the application of magnetosomes in the biomedical field, highlighting the latest advancements and exploring the future development of magnetosomes.

关键词： Magnetosome Bionic magnetosomes Magnetotactic bacteria Modification strategies biomedical applications

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FEM simulation optimization and slab method on rotating extrusion of thin-walled round tube under constant shear friction 8

FEM simulation optimization and slab method on rotating extr...

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8th International Conference of Precision Machinery and Manufacturing Technology, ICPMMT 2023

作者： Chang, K.H. Huang, B.C. Teng, H.Y. Tzou, G.Y. Department of Mold and Die Engineering National Kaohsiung University of Science and Technology Sanmin Kaohsiung City807618 Taiwan Department of Mechanical Engineering Institute of Mechatronic Engineering Cheng Shiu University Niaosong Kaohsiung83347 Taiwan School of Mechanical Materials Mechatronic and Biomedical Engineering Faculty of Engineering and Information Sciences University of Wollongong Northfields Ave. WollongongNSW2522 Australia

This research considering constant shear friction is to explore the rotating extrusion of thin-walled round tube based on FEM simulation and slab method, and compares the results of both models to realize the variations and acceptance. The effective stress, the effective strain, the velocity field, the average thickness, the extrusion force, and the extrusion torque can be obtained from this study. It reveals the average thickness obtained from rotating extrusion is more uniform than that obtained from no rotating extrusion. The FEM optimization for extrusion force can be combined with Taguchi method, the L934 orthogonal table considers the four control factors which are outer diameter to thickness ratio, frictional factor, rotating angular velocity, half die angle, and three levels. The ranking of influence factors and the optimization combination can be obtained from FEM simulation optimization. Eventually the extrusion force between FEM simulation and slab method is compared under rotating angular velocity, 0.2 rad/s, the maximum error is 10.49 % and the minimum error is -0.29%;the average error is 4.16%, so the trend is in good agreement each other. Therefore, the both models can be verified. © Published under licence by IOP Publishing Ltd.

关键词： Extrusion

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PCL-based and Hirudin-containing Composite Nanofibers for Prolonged Anticoagulation Effect

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Chemical Research in Chinese Universities 2023年第6期39卷 1023-1030页

作者： ZHENG Zhiwen DAI Xin LI Xueyang DU Chang Department of Biomaterials School of Materials Science and EngineeringSouth China University of TechnologyGuangzhou 510641P.R.China National Engineering Research Center for Tissue Restoration and Reconstruction South China University of TechnologyGuangzhou 510006P.R.China NMPA Key Laboratory for Research and Evaluation of Innovative Biomaterials for Medical Devices South China University of TechnologyGuangzhou 510006P.R.China Key Laboratory of Biomedical Materials and Engineering Ministry of EducationSouth China University of TechnologyGuangzhou 510006P.R.China

More and more concerns about health bring the increasing demand for blood contact tissue engineering *** this paper,nanoparticles of poly(lactic-co-glycolic acid)/polyethyleneimine mixed with recombinant hirudin(rHNPs)were prepared by a double emulsion solvent volatilization method,which were then loaded onto the polycaprolactone(PCL)with polydopamine(PDA)coating to form the composite nanofibers of PCL/PDA/*** hydrophilicity and mechanical properties of the composite nanofibers were improved significantly compared with pure *** morphology kept almost unchanged after 30 d of degradation in phosphate buffer saline(PBS).The anticoagulant molecule of hirudin could be gradually released from the composite scaffolds through the degradation of rHNPs in *** the concentration of rHNPs suspension was 5.0 mg/mL,the composite nanofibers could better promote the growth and proliferation of human umbilical vein endothelial cells(HUVECs).The anticoagulant ability of the composite nanofibers was also significantly improved in comparison with that of pure *** design of controlled release anticoagulant materials would alleviate the sudden release of simple fixed hirudin,which could also provide a new idea for the development of novel blood contact materials.

关键词： Recombinant hirudin Anticoagulation Drug release Composite nanofiber

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Biomass-Based Discrete Furan Oligomers as materials for Electrochromic Devices

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ACS Sustainable Chemistry and engineering 2024年第1期12卷 459-469页

作者： Atayde, Eduardo C. Fong, Guan-Lun Yeh, Jyun-Yi Matsagar, Babasaheb M. Wang, Yu-Cheng Chen, De-Chian Peng, Chi-How Li, Yi-Pei Yamauchi, Yusuke Ho, Kuo-Chuan Wu, Kevin C.-W. Molecular Science and Technology Program Taiwan International Graduate Program (TIGP-MST) Academia Sinica No. 128 Sec. 2 Academia Road Taipei 11529 Taiwan Department of Chemistry National Tsing Hua University No. 101 Sec. 2 Kuang-Fu Road Hsinchu 30013 Taiwan Department of Chemical Engineering National Taiwan University No. 1 Sec. 4 Roosevelt Road Taipei 10617 Taiwan Sustainable Chemical Science and Technology Program Taiwan International Graduate Program (TIGP-SCST) Academia Sinica No. 128 Sec. 2 Academia Road Taipei 11529 Taiwan School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology (AIBN) The University of Queensl Brisbane 4072 QLD Australia Department of Materials Process Engineering Graduate School of Engineering Nagoya University Nagoya 464-8603 Japan Institute of Polymer Science and Engineering National Taiwan University No.1 Sec. 4 Roosevelt Rd. Taipei 10617 Taiwan Department of Chemical Engineering and Materials Science Yuan Ze University No. 135 Yuandong Rd. Taoyuan 320 Taiwan

Electrochromic devices (ECDs) are materials that can undergo reversible changes in transmittance when exposed to different applied potentials. While many conjugated heterocyclic oligomers, such as oligothiophenes, have been developed for this purpose, there is no reported study on the use of discrete oligomeric furans as ECD materials. In this work, we introduce a furan trimer that can be utilized as a discrete electrochromic material, which transitions from light yellow to red and has a very high coloration efficiency of 1940 cm²/C at 507 nm. We propose that the reversible π-stack formation of the oligomer radical cations is behind this phenomenon, as evidenced by both experimental and computational results. The derivability of this oligomer from biomass and its facile synthesis make it an interesting alternative for other existing organic electrochromic materials. © 2023 American Chemical Society

关键词： electrochromism furan oligomer hydroxyalkylation−alkylation reaction solvatochromism π-stacks

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Ultrasound-activated mechanochemical reactions for controllable biomedical applications

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Smart materials in Medicine 2024年第4期5卷 461-476页

作者： Zuo, Maocheng Xiao, Rong Du, Fangxue Cheng, Chong Rodriguez, Raul D. Ma, Lang Zhu, Bihui Qiu, Li Department of Medical Ultrasound West China Hospital Sichuan University Chengdu610041 China Department of Ultrasound and Central Laboratory Sichuan Academy of Medical Sciences Sichuan Provincial People's Hospital School of Medicine University of Electronic Science and Technology of China Chengdu610072 China College of Polymer Science and Engineering State Key Laboratory of Polymer Materials Engineering Sichuan University Chengdu610065 China Research School of Chemistry & Applied Biomedical Sciences Tomsk Polytechnic University 30 Lenin Avenue Tomsk634050 Russia

Intramolecular bonds in small organic molecules, macromolecules, and organic-inorganic hybrids are broken or formed by ultrasound-activated mechanical force that can be applied with spatial and temporal precision for contactless external control of mechanochemical reactions. Ultrasound featuring non-invasiveness, high tissue penetration, and spatiotemporal controllability has shown great potential in controlling the activation of mechanochemical reactions such as chemical bond scission, natural enzyme activation, and catalytic radical generation for targeted drug or gene therapy. Here, we comprehensively summarize the latest research and future trends in ultrasound-activated mechanochemical reactions for smart biomedical applications. First, the mechanism of ultrasound-activated mechanochemical reactions will be outlined. Then, the types of mechanochemical reactions will be carefully discussed. After that, the representative biomedical applications have been summarized from a unique perspective. Finally, we systematically emphasize the current challenges and future outlooks to guide the rational design of ultrasound-activated drug release over conventional drug-loaded therapies. We believe that this review will substantially facilitate the progression and widespread utilization of ultrasound-activated mechanochemical reactions in biomedical applications. © 2024 The Authors

关键词： Targeted drug delivery

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In situ atomic-scale observation of size-dependent (de) potassiation and reversible phase transformation in tetragonal FeSe anodes

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InfoMat 2023年第1期5卷 161-171页

作者： Ran Cai Lixia Bao Wenqi Zhang Weiwei Xia Chunhao Sun Weikang Dong Xiaoxue Chang Ze Hua Ruiwen Shao Toshio Fukuda Zhefei Sun Haodong Liu Qiaobao Zhang Feng Xu Lixin Dong Beijing Advanced Innovation Center for Intelligent Robots and Systems School of Medical TechnologyBeijing Institute of TechnologyBeijingPeople's Republic of China Analysis&Testing Center Beijing Institute of TechnologyBeijingPeople's Republic of China Department of Biomedical Engineering City University of Hong KongHong KongPeople's Republic of China Shaanxi Materials Analysis and Research Center School of Materials Science and EngineeringNorthwestern Polytechnical UniversityXi'anPeople's Republic of China School of Environmental and Safety Engineering North University of ChinaTaiyuanPeople's Republic of China Department of Materials Science and Engineering College of MaterialsXiamen UniversityXiamenFujianPeople's Republic of China Department of Nanoengineering University of California San DiegoLa JollaCaliforniaUSA SEU-FEI Nano-Pico Center Key Laboratory of MEMS of Ministry of EducationSoutheast UniversityNanjingPeople's Republic of China

Potassium-ion batteries(PIBs)are considered promising alternatives to lithium-ion batteries owing to cost-effective potassium resources and a suitable redox potential of-2.93 V(vs.-3.04 V for Li+/Li).However,the exploration of appro-priate electrode materials with the correct size for reversibly accommodating large K+ions presents a significant *** addition,the reaction mecha-nisms and origins of enhanced performance remain ***,tetragonal FeSe nanoflakes of different sizes are designed to serve as an anode for PIBs,and their live and atomic-scale potassiation/depotassiation mechanisms are revealed for the first time through in situ high-resolution transmission electron *** found that FeSe undergoes two distinct structural evolutions,sequen-tially characterized by intercalation and conversion reactions,and the initial intercalation behavior is *** expansion induced by the intercalation of K+ions is observed in small-sized FeSe nanoflakes,whereas unexpected cracks are formed along the direction of ionic diffusion in large-sized *** significant stress generation and crack extension originating from the combined effect of mechanical and electrochemical interactions are elucidated by geometric phase analysis and finite-element *** the different intercalation behaviors,the formed products of Fe and K_(2)Se after full potassiation can be converted back into the original FeSe phase upon *** particular,small-sized nanoflakes exhibit better cycling perfor-mance with well-maintained structural *** article presents the first successful demonstration of atomic-scale visualization that can reveal size-dependent potassiation ***,it provides valuable guidelines for optimizing the dimensions of electrode materials for advanced PIBs.

关键词： elucidated by geometric phase analysis and finite-element analysis. Despite the different intercalation behaviors the formed products of Fe and K 2 Se after full potassiation can be converted back into the original FeSe phase upon depotassiation. In particular small-sized nanoflakes exhibit better cycling perfor- mance with well-maintained structural integrity. This article presents the first successful demonstration of atomic-scale visualization that can reveal size- dependent potassiation dynamics. Moreover it provides valuable guidelines for optimizing the dimensions of electrode materials for advanced PIBs. KEYWOR DS in situ transmission electron microscopy potassium-ion batteries potassium-ion storage mechanism size-dependent effects tetragonal FeSe

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Thermal energy dependent transient permittivity of epsilon-near-zero material

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science China(Physics,Mechanics & Astronomy) 2022年第8期65卷 96-101页

作者： Heng Wang Lixun Sun Kang Du Wending Zhang SooJin Chua Guixin Li Ting Mei MOE Key Laboratory of Material Physics and Chemistry under Extraordinary Conditions and Shaanxi Key Laboratory of Optical Information TechnologySchool of Physical Science and TechnologyNorthwestern Polytechnical UniversityXi’an710129China Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen518055China Shenzhen Institute for Quantum Science and Engineering Southern University of Science and TechnologyShenzhen518055China Department of Electrical and Computer Engineering National University of SingaporeSingapore117583Singapore LEES Program Singapore-MIT Alliance for Research&Technology(SMART)Singapore138602Singapore

Transparent conductive oxides exhibit attractive optical nonlinearity with ultrafast response and giant refractive index change near the epsilon-near-zero(ENZ) wavelength, originating from the intraband dynamics of conduction electrons. The optical nonlinearity of ENZ materials has been explained by using the overall-effective-mass and the overall-scattering-time of electrons in the extended Drude model. However, their response to optical excitation is yet the last building block to complete the theory. In this paper, the concept of thermal energy is theoretically proposed to account for the total energy of conduction electrons exceeding their thermal equilibrium value. The time-varying thermal energy is adopted to describe the transient optical response of indium-tin-oxide(ITO), a typical ENZ material. A spectrally-resolved femtosecond pump-probe experiment was conducted to verify our theory. By correlating the thermal energy with the pumping density, both the giant change and the transient response of the permittivity of ITO can be predicted. The results in this work provide a new methodology to describe the transient permittivities of ENZ materials, which will benefit the design of ENZ-based nonlinear photonic devices.

关键词： epsilon-near-zero optical nonlinearity transient response thermal energy hot electron indium tin oxide

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