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Low-cost Fabrication of PDMS Microfluidic Chamber using Digital Cutter Machine

Journal of Physics: Conference Series 2021年第1期1912卷

作者： I Anshori S Harimurti M S Hartono R R Althof L N Rizalputri M Handayani Tati L E R Mengko B Yuliarto Lab-on-a-Chip Laboratory Department of Biomedical Engineering School of Electrical Engineering Institut Teknologi Bandung Research Center for Metallurgy and Materials Indonesian Institute of Sciences (LIPI) Advanced Functional Material (AFM) Laboratory Department of Engineering Physics Faculty of Industrial Technology Institut Teknologi Bandung Research Center for Nanoscience and Nanotechnology (RCNN) Institut Teknologi Bandung

Microfluidic chamber or channel is one important tool in the lab-on-a-chip (LoC) technology, which usually serves as a platform to contain liquid analytes. The conventional method to fabricate microfluidic chamber is based on photolithography technique. However, it is a high-cost process and requires special equipment, such as mask aligners and expensive photosensitive resist material. In this work, we fabricated the microfluidic chamber and channel using a much simpler and lower-cost technique that is using PDMS as the main material and polyimide tape as the mold. Using this method, the diameter of the microfluidic pattern (channel/chamber) could be made up to as small as 1 mm and the height of the flow channel was down to tens or hundreds of μm scale-depending on the thickness of the tape. The flow test results showed that low cost and simple microfluidic fabrication method had a good performance and could potentially be further used for real analyte flow test.

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Hot Rocks Survey I: A possible shallow eclipse for LHS 1478 b

arXiv

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arXiv 2024年

作者： August, Prune C. Buchhave, Lars A. Diamond-Lowe, Hannah Mendonça, João M. Gressier, Amélie Rathcke, Alexander D. Allen, Natalie H. Fortune, Mark Jones, Kathryn D. Meier Valdés, Erik A. Demory, Brice-Olivier Espinoza, Nestor Fisher, Chloe E. Gibson, Neale P. Heng, Kevin Hoeijmakers, Jens Hooton, Matthew J. Kitzmann, Daniel Prinoth, Bibiana Eastman, Jason D. Barnes, Rory Department of Space Research and Technology Technical University of Denmark Elektrovej 328 Kgs. Lyngby2800 Denmark Space Telescope Science Institute 3700 San Martin Drive BaltimoreMD21218 United States Department of Physics and Astronomy University of Southampton Highfield SouthamptonSO17 1BJ United Kingdom School of Ocean and Earth Science University of Southampton SouthamptonSO14 3ZH United Kingdom Department of Physics and Astronomy Johns Hopkins University 3400 N. Charles Street BaltimoreMD21218 United States School of Physics Trinity College Dublin University of Dublin Dublin 2 Ireland Center for Space and Habitability University of Bern Gesellschaftsstrasse 6 Bern3012 Switzerland Physikalisches Institut University of Bern Sidlerstrasse 5 Bern3012 Switzerland Department of Physics University of Oxford Keble Road OxfordOX1 3RH United Kingdom Ludwig Maximilian University Faculty of Physics Scheinerstr. 1 MunichD-81679 Germany ARTORG Center for Biomedical Engineering Research University of Bern Murtenstrasse 50 BernCH-3008 Switzerland University College London Department of Physics & Astronomy Gower St LondonWC1E 6BT United Kingdom University of Warwick Department of Physics Astronomy & Astrophysics Group CoventryCV4 7AL United Kingdom Lund Observatory Division of Astrophysics Department of Physics Lund University Box 118 Lund221 00 Sweden Cavendish Laboratory JJ Thomson Avenue CambridgeCB3 0HE United Kingdom Space Research and Planetary Sciences Physics Institute University of Bern Gesellschaftsstrasse 6 Bern3012 Switzerland Center for Astrophysics Harvard & Smithsonian 60 Garden St CambridgeMA02138 United States Department of Astronomy University of Washington SeattleWA98105 United States

Context. M dwarf systems offer an opportunity to study terrestrial exoplanetary atmospheres due to their small size and cool temperatures. However, the extreme conditions imposed by these host stars raise question about whether their close-in rocky planets are able to retain any atmosphere at all. Aims. The Hot Rocks Survey aims to answer this question by targeting nine different M dwarf rocky planets spanning a range of planetary and stellar properties. Of these, LHS 1478 b orbits an M3-type star, has an equilibrium temperature of Teq = 585 K and receives 21 times Earth’s instellation. Methods. We observe two secondary eclipses of LHS 1478 b using photometric imaging at 15µm using the Mid-Infrared Instrument on the James Webb Space Telescope (JWST MIRI) to measure thermal emission from the dayside of the planet. We compare these values to atmospheric models to evaluate potential heat transport and CO2 absorption signatures. Results. We find that a secondary eclipse depth of 138 ± 53 ppm at the expected time for a circular orbit is preferred over a null model at 2.8σ, a moderate detection, though dynamical models do favour a non-eccentric orbit for this planet. The second observation results in a non-detection due to significantly larger unexplained systematics. Based on the first observation alone, we can reject the null hypothesis of the dark (zero Bond albedo) no atmosphere bare rock model with a confidence level of 3.3σ, though for AB = 0.2 the significance decreases to 2.1σ. The tentative secondary eclipse depth is consistent with the majority of atmospheric scenarios we considered, spanning CO2-rich atmospheres with surface pressures from 0.1 to 10 bar. However, we stress that the two observations from our program do not yield consistent results, and more observations are needed to verify our findings. The Hot Rocks Survey serves as a relevant primer for future endeavours such as the Director’s Discretionary Time (DDT) Rocky Worlds program. © 2024, CC BY.

关键词： Atmospheric pressure

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Editor-in-Chief

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IEEE Access 2024年 12卷 i-xi页

作者： Derek Abbott Sonia Aissa Anuradha Annaswamy Nirwan Ansari Jun Cai Kun-Shan Chen Yixin Chen J.-C. Chiao Ayman El-Baz Shaikh Fattah Hoay Gooi Maya Gokhale Chih-Lin Ⅰ Giuseppe Iannaccone Yumi Iwashita Bruce Jacob Abbas Jamalipour Bahram Javidi Weihua Jiang Okyay Kaynak Hulya Kirkici Germano Lambert-Torres Shengtao Li Michal Mrozowski Michele Nappi Dalma Novak Hugo Proença Yi Qian Zhihua Qu Susanto Rahardja Mehrdad Saif Ali Serpengüzel Peter H. Siegel Ashitey Trebi-Ollennu Daniela Tuninetti Ge Wang Keith A. Wear Andreas Weisshaar C. Patrick Yue Enrico Zio School of Electrical and Electronic Engineering University of Adelaide Adelaide SA Australia Institut National de la Recherche Scientifique (INRS) Québec City Canada Department of Mechanical Engineering Massachusetts Institute of Technology Cambridge MA USA Department of Electrical and Computer Engineering New Jersey Institute of Technology Newark NJ USA Concordia University Montreal Canada Guilin University of Technology Guilin China Washington University St. Louis MO USA Southern Methodist University Dallas TX USA University of Louisville/Bioengineering Department Louisville KY USA Department of Electrical and Electronic Engineering Bangladesh University of Engineering and Technology Dhaka Bangladesh Nanyang Technological University Jurong West Singapore Lawrence Livermore National Laboratory Livermore CA USA China Mobile Research Institute Beijing China University of Pisa Pisa Italy NASA-JPL California Institute of Technology Pasadena CA USA Florida Polytechnic University Lakeland FL USA The University of Sydney Sydney NSW Australia University of Connecticut Storrs CT USA Nagaoka University of Technology Nagaoka Niigata Japan Department of Electrical and Electronic Engineering Boğaziçi University Istanbul Turkey University of South Alabama Mobile AL USA Gnarus Institute Itajuba Brazil Xi’an Jiaotong University Xi’an China Gdansk University of Technology Gdansk Poland University of Salerno Fisciano Italy Octane Wireless Hanover MD USA University of Beira Interior Covilhã Portugal Department of Electrical and Computer Engineering University of NebraskaLincoln Lincoln NE USA University of Central Florida Orlando Florida USA Singapore Institute of Technology 10 Dover Dr Singapore Infocomm Technology Cluster 10 Dover Dr Singapore University of Windsor Windsor Canada Department of Physics Koç University Istanbul Turkey California Institute of Technology (CalTech) Pasadena California USA NASA-JPL Mobility and Robotics Systems S

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The Accuracy of a SmartBottle Device for Objective Assessment of Changes in Bottle Weight During Infant Feeding

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Journal of the Academy of Nutrition and Dietetics 2025年

作者： Ellie Blach Molly M. Ryder Robert Brewster Javier de la Fuente Benjamin G. Hawkins Alison K. Ventura Department of Kinesiology and Public Health Bailey College of Science and Mathematics Center for Health Research California Polytechnic State University 1 Grand Ave San Luis Obispo CA 93407 Department of Kinesiology and Public Health Bailey College of Science and Mathematics Center for Health Research California Polytechnic State University 1 Grand Ave San Luis Obispo CA 93407 Department of Biological Sciences Bailey College of Science and Mathematics California Polytechnic State University 1 Grand Ave San Luis Obispo CA 93407 Industrial Technology Packaging and Entrepreneurship Area Orfalea College of Business California Polytechnic State University 1 Grand Ave San Luis Obispo CA 93407 Departments of Electrical Engineering and Biomedical Engineering College of Engineering California Polytechnic State University 1 Grand Ave San Luis Obispo CA 93407 Department of Kinesiology and Public Health Bailey College of Science and Mathematics Center for Health Research California Polytechnic State University 1 Grand Ave San Luis Obispo CA 93407

Background Current infant feeding assessment methods are often labor-intensive for caregivers and prone to bias. Objective The present study assessed the accuracy of the SmartBottle device, which attaches to an infant feeding bottle and automatically records the amount consumed during bottle-feeding. Design This was a proof-of-concept study wherein changes in bottle weight during infant feeding interactions were simulated and compared to criterion weights. Research assistants conducted four trials to obtain SmartBottle-derived test weights and corresponding scale-derived criterion weights for bottles of various sizes and shapes and with differing volumes of formula. Each trial focused on a different bottle: 1) Dr. Brown's 120 mL, 2) Dr. Brown’s 250 mL, 3) Avent 125 mL, and 4) Avent 260 mL. Twenty-five corresponding test and criterion weights were collected for each bottle, resulting in 100 measurements total. Participants/setting Three research assistants collected data within a controlled laboratory setting. Main outcome measures SmartBottle-derived test weights and scale-derived criterion weights were the main outcome measures. Statistical analyses performed Two one-sided t-tests (TOST) were used to compare the equivalence of SmartBottle-derived test weights to scale-derived criterion weights at ±5%, ±7.5%, and ±10% of scale-derived criterion weights. Bland-Altman plots were examined to assess whether there were systematic errors in SmartBottle-derived test weights. Results The mean difference between SmartBottle-derived test weights and scale-derived criterion weights was -0.01 (90% CI, -0.02, 0.00) and was equivalent within ±5% bounds (p< 0.0001). Bland-Altman plots illustrated there was no evidence of systematic bias related to bottle weight, size, or shape. Conclusions SmartBottle-derived test weights were equivalent to scale-derived criterion weights within ±5% equivalence bounds with no evidence of bias. Further testing within real-world infant feeding conte

关键词： bottle-feeding infant feeding feeding behavior diet assessment sensors

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Regulation of height position-multi-grid motor shelter on laser electrohydraulic system of automatic beam

Regulation of height position-multi-grid motor shelter on la...

引用

AL-Noor International Conference for Science and technology (NICST)

作者： Nazar Yasir Jasim Ali Yousuf Khenyab Laith Jaafer Habeeb Biomedical Engineering Department University of Technology Baghdad Iraq Refrigeration & Air Conditioning Tech. Department Al-Salam University College Baghdad Iraq Training and Workshop Center University of Technology Baghdad Iraq

ISBN: (数字)9781728165844

ISBN: (纸本)9781728165851

This research aims to combine the work of the subsystems to regulate the height of the blade and the transverse slope of the blade. When the height adjustment system is applied to the blade, the simultaneous control is applied to the left and right hydraulic cylinders of the blade, and the side slider is adjusted only by changing the rod position of the cylinder. This can be used to reduce the pressure of the blade by reducing the pressure in the system and thus not rupturing the pipelines. This system of pipelines is maintained by reducing the pressure caused by uneven ground surfaces, thus avoiding damage to the blades and skimming tools, making it possible to operate the machine automatically without the need for constant monitoring and follow-up of the work of the machine or skimming tool.

关键词： Blades DC motors Mathematical model Oils Valves Detectors

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NMR of 31P nuclear spin singlet states in organic diphosphates

arXiv

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arXiv 2021年

作者： DeVience, Stephen J. Walsworth, Ronald L. Rosen, Matthew S. Department of Chemistry and Chemical Biology Harvard University 12 Oxford St. CambridgeMA02138 United States Harvard-Smithsonian Center for Astrophysics 60 Garden St. CambridgeMA02138 United States Department of Physics Harvard University 17 Oxford St. CambridgeMA02138 United States Athinoula A. Martinos Center for Biomedical Engineering Massachusetts General Hospital 149th Thirteenth St. CharlestownMA02129 United States Scalar Magnetics Llc 3 Harolwood Ct. Apt C Windsor MillMD21244 United States Quantum Technology Center University of Maryland 8228 Paint Branch Dr. College ParkMD20742 United States

31P NMR and MRI are commonly used to study organophosphates that are central to cellular energy metabolism. In some molecules of interest, such as adenosine diphosphate (ADP) and nicotinamide adenine dinucleotide (NAD), pairs of coupled 31P nuclei in the diphosphate moiety should enable the creation of nuclear spin singlet states, which may be long-lived and can be selectively detected via quantum filters. Here, we show that 31P singlet states can be created on ADP and NAD, but their lifetimes are shorter than T1 and are strongly sensitive to pH. Nevertheless, the singlet states were used with a quantum filter to successfully isolate the 31P NMR spectra of those molecules from the adenosine triphosphate (ATP) background signal. Copyright © 2021, The Authors. All rights reserved.

关键词： Nuclear magnetic resonance spectroscopy

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MedShapeNet - A Large-Scale Dataset of 3D Medical Shapes for Computer Vision

arXiv

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arXiv 2023年

作者： Li, Jianning Zhou, Zongwei Yang, Jiancheng Pepe, Antonio Gsaxner, Christina Luijten, Gijs Qu, Chongyu Zhang, Tiezheng Chen, Xiaoxi Li, Wenxuan Wodzinski, Marek Friedrich, Paul Xie, Kangxian Jin, Yuan Ambigapathy, Narmada Nasca, Enrico Solak, Naida Melito, Gian Marco Vu, Viet Duc Memon, Afaque R. Schlachta, Christopher De Ribaupierre, Sandrine Patel, Rajnikant Eagleson, Roy Chen, Xiaojun Mächler, Heinrich Kirschke, Jan Stefan de la Rosa, Ezequiel Christ, Patrick Ferdinand Li, Hongwei Bran Ellis, David G. Aizenberg, Michele R. Gatidis, Sergios Küstner, Thomas Shusharina, Nadya Heller, Nicholas Andrearczyk, Vincent Depeursinge, Adrien Hatt, Mathieu Sekuboyina, Anjany Löffler, Maximilian Liebl, Hans Dorent, Reuben Vercauteren, Tom Shapey, Jonathan Kujawa, Aaron Cornelissen, Stefan Langenhuizen, Patrick Ben-Hamadou, Achraf Rekik, Ahmed Pujades, Sergi Boyer, Edmond Bolelli, Federico Grana, Costantino Lumetti, Luca Salehi, Hamidreza Ma, Jun Zhang, Yao Gharleghi, Ramtin Beier, Susann Sowmya, Arcot Garza-Villarreal, Eduardo A. Balducci, Thania Angeles-Valdez, Diego Souza, Roberto Rittner, Leticia Frayne, Richard Ji, Yuanfeng Ferrari, Vincenzo Chatterjee, Soumick Dubost, Florian Schreiber, Stefanie Mattern, Hendrik Speck, Oliver Haehn, Daniel John, Christoph Nürnberger, Andreas Pedrosa, João Ferreira, Carlos Aresta, Guilherme Cunha, António Campilho, Aurélio Suter, Yannick Garcia, Jose Lalande, Alain Vandenbossche, Vicky Van Oevelen, Aline Duquesne, Kate Mekhzoum, Hamza Vandemeulebroucke, Jef Audenaert, Emmanuel Krebs, Claudia van Leeuwen, Timo Vereecke, Evie Heidemeyer, Hauke Röhrig, Rainer Hölzle, Frank Badeli, Vahid Krieger, Kathrin Gunzer, Matthias Chen, Jianxu van Meegdenburg, Timo Dada, Amin Balzer, Miriam Fragemann, Jana Jonske, Frederic Rempe, Moritz Malorodov, Stanislav Bahnsen, Fin H. Seibold, Constantin Jaus, Alexander Marinov, Zdravko Jaeger, Paul F. Stiefelhagen, Rainer Santos, Ana Sofia Lindo, Mariana Ferreira, André Alves, Victor Kamp, Michael Abourayya, Amr Nensa, Felix Hörst, Fabian Brehmer, Alexander Hein Girardetstraße 2 Essen45131 Germany Graz University of Technology Inffeldgasse 16c Graz8010 Austria Graz Austria The Department of Computer Science Johns Hopkins University Malone Hall 3400 N Charles St BaltimoreMD21218 United States Rte Cantonale Lausanne1015 Switzerland The Department of Measurement and Electronics AGH University of Science and Technology Krakow Poland Sierre Switzerland Department of Biomedical Engineering University of Basel Hegenheimermattweg Allschwil167C CH-4123 Switzerland The Boston College 140 Commonwealth Ave Chestnut HillMA02467 United States University Hospital B7-200 339 Windermere Road LondonN6A 5A5 Canada The Department of Radiology Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai200240 China The Research Center for Connected Healthcare Big Data ZhejiangLab Zhejiang Hangzhou311121 China The Faculty of Statistics Technical University Dortmund August-Schmidt-Straße 1 Dortmund44227 Germany The Institute of Mechanics Graz University of Technology Kopernikusgasse 24/IV Graz8010 Austria The Institute of Biomedical Manufacturing and Life Quality Engineering State Key Laboratory of Mechanical System and Vibration School of Mechanical Engineering Shanghai Jiao Tong University 800 Dongchuan Road Shanghai200240 China The Department of Cardiac Surgery Medical University Graz Auenbruggerplatz 29 Graz8036 Austria The Department of Diagnostic and Interventional Radiology University Hospital Giessen Justus-Liebig-University Giessen Klinikstraße 33 Giessen35392 Germany The Department of Mechanical Engineering Mehran University of Engineering and Technology Jamshoro Sindh76062 Pakistan The Institute of Medical Robotics Shanghai Jiao Tong University Shanghai China The Geschäftsführender Oberarzt Abteilung für Interventionelle und Diagnostische Neuroradiologie Universitätsklinikum der Technischen Universität München Ismaningerstr. 22 München81675 Germany icometrix Kolonel Be

Prior to the deep learning era, shape was commonly used to describe the objects. Nowadays, state-of-the-art (SOTA) algorithms in medical imaging are predominantly diverging from computer vision, where voxel grids, meshes, point clouds, and implicit surface models are used. This is seen from numerous shape-related publications in premier vision conferences as well as the growing popularity of ShapeNet (about 51,300 models) and Princeton ModelNet (127,915 models). For the medical domain, we present a large collection of anatomical shapes (e.g., bones, organs, vessels) and 3D models of surgical instrument, called MedShapeNet, created to facilitate the translation of data-driven vision algorithms to medical applications and to adapt SOTA vision algorithms to medical problems. As a unique feature, we directly model the majority of shapes on the imaging data of real patients. As of today, MedShapeNet includes 23 datasets with more than 100,000 shapes that are paired with annotations (ground truth). Our data is freely accessible via a web interface and a Python application programming interface (API) and can be used for discriminative, reconstructive, and variational benchmarks as well as various applications in virtual, augmented, or mixed reality, and 3D printing. Exemplary, we present use cases in the fields of classification of brain tumors, skull reconstructions, multi-class anatomy completion, education, and 3D printing. In future, we will extend the data and improve the interfaces. The project pages are: https://***/ and https://***/Jianningli/*** Codes 68T01 © 2023, CC BY.

关键词： Large dataset

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Establishment of salivary tissue-organoid biorepository: characterizing salivary gland stem/progenitor cells and novel differentiation marker PSMA/FOLH1

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npj Regenerative Medicine 2025年第1期10卷 1-19页

作者： Aalam, Syed Mohammed Musheer Varela, Ana Rita Khaderi, Aalim Mondesir, Ronsard J. Mun, Dong-Gi Ding, Andrew Lombaert, Isabelle M. A. Coppes, Rob P. Emperumal, Chitra Priya Pandey, Akhilesh Janus, Jeffrey R. Kannan, Nagarajan Department of Laboratory Medicine and Pathology Mayo Clinic RochesterMN United States Biologic and Materials Sciences and Prosthodontics University of Michigan School of Dentistry 1011 N. University Ave Ann ArborMI United States Biointerfaces Institute University of Michigan 2900 Plymouth Rd Ann ArborMI United States Departments of Radiation Oncology and Biomedical Sciences University of Groningen University Medical Center Groningen Groningen Netherlands Center for Individualized Medicine Mayo Clinic RochesterMN United States Manipal Academy of Higher Education Karnataka Manipal India Department of Otolaryngology-Head and Neck Surgery Mayo Clinic JacksonvilleFL United States Center for Regenerative Biotherapeutics Mayo Clinic RochesterMN United States Mayo Clinic Comprehensive Cancer Center Mayo Clinic RochesterMN United States Department of Biological Engineering Massachusetts Institute of Technology CambridgeMA United States

The salivary gland (SG) is vital for oral function and overall health through secretion of saliva. However salivary dysfunction due to aging, medications, autoimmune disorders, and cancer treatments poses significant challenges. We established the first diverse and clinically annotated salivary regenerative biobank at Mayo Clinic to study salivary gland stem/progenitor cells (SGSPCs). Optimization of cell isolation and progenitor assays revealed SGSPCs enriched within the CD24/EpCAM/CD49f+ and PSMA- phenotypes of both submandibular and parotid glands, with clonal differentiation assays highlighting heterogeneity. Induction of PSMA/FOLH1 expression was associated with SGSPC differentiation. Using mass spectrometry-based single cell proteomics, we identified 2461 proteins in SGSPC-enriched cells, including co-expressed cytokeratins, expressed in rare salivary ductal basal cells. Additionally, PRDX, a unique class of peroxiredoxin peroxidases enriched in SGSPCs, demonstrated H2O2-dependent growth, suggesting a role in salivary homeostasis. These findings provide a foundation for SGSPC research and potential regenerative therapies for salivary gland dysfunction. © The Author(s) 2025.

关键词： Proteomics

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Antiplasmodial Peptaibols Act Through Membrane Directed Mechanisms

SSRN

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SSRN 2022年

作者： Collins, Jennifer E. Lee, Jin Woo Rocamora, Frances Saggu, Gagandeep S. Wendt, Karen L. Pasaje, Charisse Flerida A. Smick, Sebastian Santos, Natalia Mojica Paes, Raphaella Jiang, Tiantian Mittal, Nimisha Luth, Madeline R. Chin, Taylor Chang, Howard McLellan, James L. Morales-Hernandez, Beatriz Hanson, Kirsten K. Niles, Jacquin C. Desai, Sanjay A. Winzeler, Elizabeth A. Cichewicz, Robert H. Chakrabarti, Debopam Division of Molecular Biology and Microbiology Burnett School of Biomedical Sciences University of Central Florida 12722 Research Parkway OrlandoFL32826 United States Department of Chemistry and Biochemistry Institute for Natural Products Applications & Research Technologies University of Oklahoma 101 Stephenson Parkway NormanOK73019 United States Division of Host-Microbe Systems & Therapeutics Department of Pediatrics University of California San Diego 9500 Gilman Dr La Jolla CA92093 United States Laboratory of Malaria and Vector Research National Institute of Allergy and Infectious Diseases National Institutes of Health 12735 Twinbrook Parkway RockvilleMD20852 United States Department of Molecular Microbiology and Immunology South Texas Center for Emerging Infectious Diseases University of Texas at San Antonio 1 USTSA Circle San AntonioTX78249 United States Department of Biological Engineering Massachusetts Institute of Technology 21 Ames St #56-651 CambridgeMA02142 United States

Our previous study identified 52 antiplasmodial peptaibols isolated from Trichoderma and Hypocrea fungal species. To understand their antiplasmodial mechanism of action, we conducted phenotypic assays, in vitro evolution of resistance, and transcriptome analysis of the most potent peptaibol, harzianin NPDG I (HZ NPDG-I). This, and two additional peptaibols were compared for both their killing action and stage dependency, each showing a loss of digestive vacuole (DV) content in ultrastructural analysis. HZ-NPDG-I demonstrated a stepwise increase in DV pH, along with impaired DV membrane permeability, and the ability to form ion channels upon reconstitution in planar lips membranes. This compound showed no signs of cross resistance to targets of current clinical candidates, and three independent lines evolved to resist HZ NPDG-I acquired non synonymous changes in the P. falciparum multidrug resistance transporter, ***, conditional knockdown of PfMDR1 showed varying activity based on peptaibol length, suggesting distinct activities. © 2022, The Authors. All rights reserved.

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Correction to: Detecting focal cortical dysplasia lesions from FLAIR-negative images based on cortical thickness

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biomedical engineering online 2020年第1期19卷 16页

作者： Cuixia Feng Hulin Zhao Maoyu Tian Miaomiao Lu Junhai Wen Department of Biomedical Engineering School of Life Science Beijing Institute of Technology Beijing China. 786733550@***. Sixth Medical Center of PLA General Hospital Beijing China. Department of Biomedical Engineering School of Life Science Beijing Institute of Technology Beijing China. Department of Biomedical Engineering School of Life Science Beijing Institute of Technology Beijing China. wenjh@***.

It was highlighted that the original article [1] contained an error in the Quantitative evaluation of Methods. A bracket was misplaced in the formula. This Correction article shows the incorrect and correct formula.

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