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DARCS: Memory-Efficient Deep Compressed Sensing Reconstruction for Acceleration of 3D Whole-Heart Coronary MR Angiography

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IEEE Transactions on Medical Imaging 2025年第5期44卷 2105-2119页

作者： Xue, Zhihao Yang, Fan Gao, Juan Chen, Zhuo Peng, Hao Zou, Chao Jin, Hang Hu, Chenxi Shanghai Jiao Tong University National Engineering Research Center of Advanced Magnetic Resonance Technologies for Diagnosis and Therapy School of Biomedical Engineering Shanghai200240 China Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Guangdong Shenzhen518055 China Fudan University Shanghai Medical Imaging Institute Department of Radiology Zhongshan Hospital Shanghai200032 China

Three-dimensional coronary magnetic resonance angiography (CMRA) requires reconstruction algorithms that can significantly suppress the artifacts encountered in heavily undersampled acquisitions. While unrolling-based deep reconstruction methods have achieved state-of-the-art performance on 2D image recons- truction, their application in 3D reconstruction is hindered by the large amount of memory required to train an unrolled network. In this study, we propose a memory-efficient deep compressed sensing method that employs a sparsifying transform based on a pre-trained artifact estimation network. The artifact image estimated by a well-trained network is expected to be sparse when the input image is artifact-free and less sparse when the input image has artifacts. Thus, the artifact estimation network can be used as an inherent sparsifying transform. The proposed method, De-Aliasing Regularization-based Compressed Sensing (DARCS), was compared with a patch-based low-rank method, de-aliasing generative adversarial network (DAGAN), 3D model-based deep learning (MoDL), plug-and-play, and AI-assisted compressed sensing (AI-CS) in terms of 3D CMRA acceleration. The results demonstrate that DARCS surpasses the reconstruction quality of the comparison methods, by approximately 2 dB in peak signal-to-noise ratio (PSNR). Furthermore, the proposed method generalizes well to different undersampling rates, patterns, and noise levels, with a memory usage of only 63% of that needed by 3D MoDL. In conclusion, DARCS improves reconstruction quality for 3D CMRA with reduced memory burden. © 1982-2012 IEEE.

关键词： Image reconstruction

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fMRI Activity Slop Feature with Poincare Plot for Emotion Classification 6th

fMRI Activity Slop Feature with Poincare Plot for Emotion Cl...

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6th International Conference on biomedical and Health Informatics, ICBHI 2024

作者： Huang, Po-Han Lin, Yu-Chen Lu, Shao-Huang Wu, Shi-Yi Tsai, Cheng-Lun Lin, Kang-Ping Electrical Engineering Department Chung Yuan Christian University Taoyuan Taiwan Technology Translation Center for Medical Device Chung Yuan Christian University Taoyuan Taiwan Biomedical Engineering Department Chung Yuan Christian University Taoyuan Taiwan Department of Electrical Engineering Chung Yuan Christian University Taoyuan Taiwan

ISBN: (纸本)9783031863226

In this study, we combined fMRI (functional Magnetic Resonance Imaging) data and Poincare plots derived from PPG (Photoplethysmography) to investigate the relationship between brain activity captured by fMRI and PPG signals and mood classification. The study focused on extracting features from the fMRI data and using these features along with the heart rate variability index derived from the Poincare plot to categorize mood. The study used the XGBOOST model for classification, and the accuracy varied depending on the model and mood classification. The results of this study suggest that the combination of fMRI and HRV features can be effective for mood classification. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

关键词： Magnetic resonance imaging

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Biomimetic 3D printing of photocrosslinkable biodegradable elastomers-modified hybrid scaffolds as instructive platforms for bone tissue regeneration

Smart Materials in Medicine

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Smart Materials in Medicine 2025年第1期6卷 95-107页

作者： Zhou, Panyu Wang, Jiayi Wang, Hongrui Pan, Hao Shi, Hengsong Fu, Yu Yuan, Yuan Wang, Yang Gan, Qi Liu, Changsheng Department of Orthopedics Changhai Hospital Naval Medical University Shanghai200082 China School of Materials Science and Engineering Key Laboratory for Ultrafine Materials of Ministry of Education and Engineering Research Center for Biomedical Materials of Ministry of Education East China University of Science and Technology Shanghai200237 China School of Aerospace Engineering and Applied Mechanics Tongji University Zhangwu Road 100 Shanghai200092 China

3D printing is regarded as an ideal method for large-scale bone defect repair. A rapid curing rate and strong mechanical properties throughout the product's shelf life are key development goals in 3D-printed bone repair biomaterials. To achieve this goal, we developed a 3D-printable organic/inorganic composite ink featuring rapid curing and highly customizable properties. After 3D printing, the nanocomposite ink of poly (glyceryl sebacate)-2-chlorocinnamoyl chloride/β-tricalcium phosphate (PGS-CC/β-TCP) undergoes short-term light crosslinking to form a biomimetic network of inorganic-organic composite materials. The resulting bone repair scaffold possesses excellent mechanical properties, significantly promotes cell adhesion and proliferation, and demonstrates good in vitro osteogenic activity, angiogenic performance, and mineralization capability. Moreover, the PGS-CC/β-TCP 3D-printed scaffold exhibits good degradation performance, retaining its mechanical properties even after four weeks of degradation. The PGS-CC(1:2)/β-TCP composite scaffold can effectively repair severe cranial bone defects in rats, showing optimal in vivo osteogenic and degradation performance at 6 and 12 weeks. With these advantages, this innovative 3D-printed biomaterial has great clinical application prospects for large segment bone repair and provides new opportunities for other complex reconstructions. © 2025 The Authors

关键词： Bone

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Enhancing corrosion resistance of MAO coatings on Al alloy LY12 through in situ co-doping with zinc phosphate and cerium phosphate

Corrosion Communications

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Corrosion Communications 2025年第1期17卷 35-43页

作者： Chao Yang Tao Ying Aihui Huang Jian Huang Pinghu Chen Paul K.Chu Xiaoqin Zeng National Engineering Research Center of Light Alloy Net Forming School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai Key Laboratory of Advanced High-Temperature Materials and Precision Forming School of Materials Science and Engineering Shanghai Jiao Tong University Department of Chemistry University of Munich(LMU) College of Mechanical Engineering Key Laboratory of Hunan Province of Equipment Safety Service Technology under Extreme Environment University of South China Department of Physics Department of Materials Science&Engineering and Department of Biomedical Engineering City University of Hong Kong

Corrosion of aluminum（Al） alloys during service limits many applications. Micro-arc oxidation（MAO） coatings can enhance corrosion resistance, but porous defects in the films undermine their effectiveness. Here, by mixing a phosphate electrolyte with soluble Zn and Ce salts, zinc phosphate and cerium phosphate co-doped MAO corrosion-resistant coating is prepared on Al alloy LY12. Zinc phosphate and cerium phosphate are incorporated in situ to form an amorphous encapsulated nanocrystalline structure. During long-term corrosion, Zn2+is released and deposited as corrosion products Zn（OH）2to cover weak corrosion micro-regions in the coating. Simultaneously, Ce3+released from MAO coating co-doped with zinc phosphate/cerium phosphate forms Zn（OH）2/Ce（OH）3due to the small solubility product Kspto further enhance corrosion resistance. Compared to pristine Al alloy,corrosion potential increases from -1.306 to -0.819 VSCE, and corrosion current density decreases by 4 orders of magnitude from 2.6 × 10-6to 2.5 × 10-10A·cm-2. Co-doped MAO coating significantly enhances corrosion resistance of Al alloy LY12 and shows great potential for a wide range of applications.

关键词： Aluminum alloys Micro-arc oxidation coating Corrosion resistance Zinc phosphate Cerium phosphate

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Toward Lung Ultrasound Automation: Fully Autonomous Robotic Longitudinal and Transverse Scans Along Intercostal Spaces

IEEE Transactions on Medical Robotics and Bionics

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IEEE Transactions on Medical robotics and Bionics 2025年第2期7卷 768-781页

作者： Lei, Long Hu, Yingbai Jiang, Zixing Miao, Juzheng Luo, Xiao Zhang, Yu Wang, Qiong Wang, Shujun Li, Zheng Heng, Pheng-Ann The Chinese University of Hong Kong Department of Computer Science and Engineering Hong Kong Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Shenzhen518055 China The Chinese University of Hong Kong Multi-Scale Medical Robotics Centre Ltd. Hong Kong The Chinese University of Hong Kong Department of Surgery Hong Kong Shenzhen Institute of Advanced Technology Chinese Academy of Sciences Guangdong Provincial Key Laboratory of Computer Vision and Virtual Reality Technology Shenzhen518055 China The Hong Kong Polytechnic University Department of Biomedical Engineering Hong Kong Chow Yuk Ho Technology Centre for Innovative Medicine Li Ka Shing Institute of Health Sciences Multiscale Medical Robotics Centre Ltd. The Chinese University of Hong Kong Department of Surgery Hong Kong

Lung ultrasound scanning is essential for diagnosing lung diseases. The scan effectiveness critically depends on both longitudinal and transverse scans through intercostal spaces to reduce rib shadowing interference, as well as maintaining the probe perpendicular to pleura for pathological artifact generation. Achieving this level of scan quality often depends heavily on the experience of doctors. Robotic ultrasound scanning shows promise, but currently lacks a direct path planning method for intercostal scanning, and probe orientation does not consider imaging differences between lungs and solid organs. In this paper, we aim to fully automate two fundamental operations in lung ultrasound scanning: longitudinal and transverse scans. We propose pioneering path planning methods along intercostal spaces and innovative solutions for adaptive probe posture adjustment using real-time pleural line feedback, specifically addressing the unique characteristics of lung ultrasound scanning. This ensures the acquisition of high-quality, diagnostically meaningful ultrasound images. In addition, we develop a robotic lung ultrasound system to validate the proposed methods. Extensive experimental results on two volunteers and a chest phantom confirm the efficacy of our methods, and demonstrate the system's feasibility in automated lung ultrasound examinations. Our work lays a solid foundation for automated robotic complete lung scanning. © 2018 IEEE.

关键词： Motion planning

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Randomly COMMITting: Iterative Convex Optimization for Microstructure-Informed Tractography 15th

Randomly COMMITting: Iterative Convex Optimization for Micr...

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15th International Workshop on Computational Diffusion MRI, CDMRI 2024, held in conjunction with 27th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2024

作者： Persson, Sanna Wan, Xinyi Moreno, Rodrigo Department of Biomedical Engineering and Health Systems KTH Royal Institute of Technology Huddinge Sweden Department of Radiology and Nuclear Medicine Erasmus MC Cancer Institute University Medical Center Rotterdam Netherlands MedTechLabs BioClinicum Karolinska University Hospital Solna Sweden

ISBN: (纸本)9783031869198

Tractography is extensively utilized in brain connectivity studies using diffusion magnetic resonance imaging (dMRI) data. However, the presence of anatomically implausible and redundant streamlines is a significant challenge. Several tractogram filtering methods have been developed to eliminate false-positive streamlines and address these issues. This study introduces a tractography filtering method – Randomized COMMIT (rCOMMIT) – that is based on the Convex Optimization Modeling for Microstructure Informed Tractography (COMMIT) filtering method. The method aims to mitigate the biases of COMMIT for individual streamlines by assessing each streamline in multiple tractogram compositions to estimate an acceptance rate per streamline. In order to reduce the computational cost, this acceptance rate is used to create pseudo-labels that are used to train neural network classifiers in a semi-supervised manner. Specifically, we train a 1D-convolutional network on streamline characteristics, achieving an area under the receiver operating characteristic curve (AUC ROC) of approximately 90% in distinguishing between plausible and non-plausible streamlines. The results from rCOMMIT are compared with those from randomized SIFT, and the intersections between the two methods are analyzed in relation to the streamline acceptance agreement. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2025.

关键词： Semi-supervised learning

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Iterative optimization algorithm with structural prior for artifacts removal of photoacoustic imaging

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Photoacoustics 2025年 44卷

作者： Zhang, Yu Li, Shuang Wang, Yibing Sun, Yu Huang, Tingting Xiang, Wenyi Li, Changhui Department of Biomedical Engineering College of Future Technology Peking University Beijing China School of Electrical and Electronic Engineering Nanyang Technological University Singapore Singapore National Biomedical Imaging Center Peking University Beijing China

In reality, photoacoustic imaging (PAI) is generally influenced by artifacts caused by sparse array or limited view. In this work, to balance the computing cost and artifact removal performance, we propose an iterative optimization method that does not need to repeat solving forward model for every iteration circle, called the regularized iteration method with structural prior (RISP). The structural prior is a probability matrix derived from multiple reconstructed images via randomly selecting partial array elements. High-probability values indicate high coherency among multiple reconstruction results at those positions, suggesting a high likelihood of representing true imaging results. In contrast, low-probability values indicate higher randomness, leaning more towards artifacts or noise. As a structural prior, this probability matrix, together with the original PAI result using all array elements, guides the regularized iteration of the PAI results. The simulation and real animal and human PAI study results demonstrated our method can substantially reduce image artifacts, as well as noise. © 2025 The Authors

关键词： Photointerpretation

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Degradation behavior of pure Mg in the physiological medium and growth mechanism of surface corrosion product films

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Journal of Magnesium and Alloys 2025年第4期13卷 1523-1535页

作者： Wang, Chenyu Sun, Mingshan Yang, Chao Wang, Haiyang Wang, Jie Mao, Lin Yang, Yao Ying, Tao Chu, Paul K. Zeng, Xiaoqin National Engineering Research Center of Light Alloy Net Forming School of Materials Science and Engineering Shanghai Jiao Tong University Shanghai200240 China Kunming Branch of the 705 Research Institute of CSSC Kunming650101 China Shanghai Institute for Minimally Invasive Therapy School of Medical Instrument and Food Engineering University of Shanghai for Science and Technology Shanghai200093 China Department of Physics Department of Materials Science & Engineering and Department of Biomedical Engineering City University of Hong Kong Tat Chee Avenue Hong Kong Kowloon Hong Kong

Pure Mg boasting a relatively small corrosion rate is a potential biodegradable metal material for implants. However, its degradation behavior in the complex physiological environment is still a lack of understanding. In this work, we investigated the effect of corrosion product film layers on the degradation behavior of pure Mg in physiological environments. Pure Mg shows a faster corrosion rate in simulated body fluid (SBF) compared to NaCl solution. Hydrogen evolution experiments indicate that the degradation rate of pure Mg in SBF decreases rapidly within the first 12 h but stabilizes afterward. The rapid deposition of low-solubility calcium phosphate on the pure Mg in SBF provides protection to the substrate, resulting in a gradual decrease in the degradation rates. Consequently, the corrosion product film of pure Mg formed in SBF exhibits a layered structure, with the upper layer consisting of dense Ca3(PO4)2/Mg3(PO4)2 and the lower layer consisting of Mg(OH)2/MgO. Electrochemical impedance spectroscopy (EIS) shows that the resistance of the corrosion product film increases over time, indicating gradual strengthening of the corrosion resistance. The 4-week degradation results in the femoral marrow cavity of mice are consistent with the result in SBF in vitro. © 2024

关键词： Corrosion rate

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One-step fabrication of ultrathin porous Janus membrane within seconds for waterproof and breathable electronic skin

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Science Bulletin 2025年第5期70卷 712-721页

作者： Yufeng Ni Bing Li Chengzhen Chu Shaofan Wang Yujie Jia Shichun Cao Rasoul Esmaeely Neisiany Chuanglong He Shuo Chen Zhengwei You State Key Laboratory of Advanced Fiber Materials Institute of Functional MaterialsCollege of Materials Science and EngineeringResearch Base of Textile Materials for Flexible Electronics and Biomedical Applications(China Textile Engineering Society)Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative MedicineShanghai Key Laboratory of Lightweight CompositeDonghua UniversityShanghai 201620China College of Biological Science and Medical Engineering Donghua UniversityShanghai 201620China Department of Materials and Polymer Engineering Faculty of EngineeringHakim Sabzevari UniversitySabzevar***Iran Biotechnology Centre Silesian University of TechnologyGliwice44-100Poland

It remains a challenge for a simple and scalable method to fabricate ultrathin porous Janus membranes for stretchable on-skin ***,we propose a one-step droplet spreading phase separation strategy to prepare an ultrathin and easily collected Janus thermoplastic polyurethane(TPU)membrane within *** metal-ion solvation structure mitigated migration kinetics to delay TPU solution demixing,promoting the further penetration of the coagulating ***,the developed membranes,with an average preparation rate of 25.2 cm^(2)s^(−1),had a thickness of 5μm,and the water vapor transmission rate was determined to be 663 g m^(−2) d^(−1).The small pore layer having an average pore size of 1.7μm effectively blocked external liquid *** porous Janus TPU membrane coated by liquid metal served as a building block to develop a new generation of monolithic stretchable electronics with simultaneous high permeability and waterproofness.

关键词： porous polyurethane kinetics

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Screening of Chinese giant salamander meat hydrolysates with DPP-Ⅳinhibitory activity and systematic elucidation of their hypoglycemic functions in mouse model

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Food Science and Human Wellness 2025年第4期14卷 1305-1317页

作者： Shucheng Li Changge Guan Yi Wang Haihong Chen Wei Li Songjun Wang Chong Zhang Xinhui Xing Key Laboratory for Industrial Biocatalysis Ministry of Education of ChinaDepartment of Chemical EngineeringTsinghua UniversityBeijing 100084China School of Life Science and Technology Tokyo Institute of TechnologyYokohama 225-8501Japan Institute of Biopharmaceutical and Health Engineering Tsinghua Shenzhen International Graduate SchoolShenzhen 518055China Henan Giant Salamander Protection and Development Association Luoyang 471000China. Center for Synthetic and Systems Biology Tsinghua UniversityBeijing100084China Institute of Biomedical Health Technology and Engineering Shenzhen Bay LaboratoryShenzhen 518055China

Type 2 diabetes(T2D)presents a significant health challenge,underscoring the need for functional foods and nutraceutical hypoglycemic bioactive peptides for its *** study investigates the potential of proteolytic hydrolysate from artificially cultivated Chinese giant salamander(CGS)meat,a rich protein source,as a preventive strategy for *** produced a CGS meat hydrolysate(CGSh)and demonstrated its ability to inhibit the T2D drug target dipeptidyl peptidaseⅣ(DPP-Ⅳ)through in vitro *** identified 5 peptides(WRPPDH,WAPPSKD,IPDSPF,IPEMIF,and VPIAVPT)with high DPP-Ⅳinhibitory activity in CGSh,suggesting its potential antidiabetic *** vivo experiments showed that CGSh effectively reduced insulin resistance in mice induced with a high-fat diet,as evidenced by a slower increase in blood glucose levels and a decreased HOMA-IR index.16S rRNA sequencing analysis revealed that CGSh improved gut microbial homeostasis,promoting beneficial microorganisms and reducing harmful *** analyses identified an increase in valeric acid levels and highlighted nine potential biomarker *** inhibiting metabolic pathways such as AGE-RAGE,CGSh might also prevent diabetic complications and reduce *** findings suggest that CGSh has a promising hypoglycemic effect,making it a potential functional food ingredient for T2D prevention and treatment.

关键词： Chinese giant salamander Hypoglycemic effects Bioactive peptides Dipeptidyl dipeptidaseⅣ Multi-omics analysis

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