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检索条件"机构=Department of Biostatistics and Programming"
48 条 记 录,以下是1-10 订阅
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Considerations on trial design and data analysis for multi-regional clinical trials
Considerations on trial design and data analysis for multi-r...
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2017第七届临床评价方法与应用国际研讨会暨生物统计国际研讨会
作者: Hui Quan Biostatistics and Programming Department of Sanofi
来源: 评论
Vitamin D intake and cardiovascular mortality in the NHANES i epidemiological follow-up study cohort
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Journal of Dietary Supplements 2012年 第2期9卷 79-89页
作者: Fan, Chunpeng Nieto, F. Javier Bautista, Leonelo E. Fine, Jason P. Department of Biostatistics and Programming Sanofi U.S. Inc. Bridgewater NJ 08807 55 Corporate Drive United States Department of Population Health Sciences University of Wisconsin Madison WI United States Department of Biostatistics University of North Carolina Chapel Hill NC United States
The objective of the present study was to determine whether vitamin D intake is associated with CVD mortality in a general population sample. The association between vitamin D intake and CVD mortality (ICD-9 code 4104... 详细信息
来源: 评论
Bayesian methods for the analysis of early-phase oncology basket trials with information borrowing across cancer types
arXiv
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arXiv 2020年
作者: Jin, Jin Riviere, Marie-Karelle Luo, Xiaodong Dong, Yingwen Department of Biostatistics Johns Hopkins Bloomberg School of Public Health BaltimoreMD United States Department of Biostatistics and Programming Research and Development Sanofi Chilly-Mazarin France Department of Biostatistics and Programming Sanofi BridgewaterNJ United States Department of Biostatistics and Programming Oncology Sanofi CambridgeMA United States
Research in oncology has changed the focus from histological properties of tumors in a specific organ to a specific genomic aberration potentially shared by multiple cancer types. This motivates the basket trial, whic... 详细信息
来源: 评论
Sequential Monitoring of Conditional Randomization Tests: Generalized Biased Coin Designs
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Sequential Analysis 2008年 第3期27卷 234-253页
作者: Yanqiong Zhang Yanqiong.Zhang@*** Rosenberger, William F. Department of Biostatistics and Programming Sanofi-Aventis Malvern Pennsylvania USA Department of Statistics George Mason University Fairfax Virginia USA
For the generalized biased coin class of randomization procedures, Smythe (1988) proved asymptotic normality of the conditional linear rank test. Clinical trialists often undertake interim analysis to determine whethe... 详细信息
来源: 评论
Dimension reduction with expectation of conditional difference
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Statistical Theory and Related Fields 2023年 第3期7卷 188-201页
作者: Wenhui Sheng Qingcong Yuan Department of Mathematical and Statistical Sciences Marquette UniversityMilwaukeeWIUSA Biostatistics and Programming SanofiUSBridgewaterNJUSA
In this article,we introduce a flexible model-free approach to sufficient dimension reduction analysis using the expectation of conditional difference *** any strict conditions,such as linearity condition or constant ... 详细信息
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Sequential monitoring of conditional randomization tests: Generalized biased coin designs
Sequential monitoring of conditional randomization tests: Ge...
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作者: Zhang, Yanqiong Rosenberger, William F. Department of Biostatistics and Programming Sanofi-Aventis Malvern PA United States Department of Statistics George Mason University Fairfax VA United States Sanofi-Aventis 9 Great Valley Parkway Malvern PA 19355 United States
For the generalized biased coin class of randomization procedures, Smythe (1988) proved asymptotic normality of the conditional linear rank test. Clinical trialists often undertake interim analysis to determine whethe... 详细信息
来源: 评论
A Seamless Phase II/III Design with Dose Optimization for Oncology Drug Development
arXiv
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arXiv 2024年
作者: Li, Yuhan Zhang, Yiding Mi, Gu Lin, Ji Department of Statistics University of Illinois Urbana-Champaign United States Biostatistics and Programming Sanofi France
The US FDA’s Project Optimus initiative that emphasizes dose optimization prior to marketing approval represents a pivotal shift in oncology drug development. It has a ripple effect for rethinking what changes may be... 详细信息
来源: 评论
Change-Point Analysis of Survival Data with Application in Clinical Trials
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Open Journal of Statistics 2014年 第9期4卷 663-677页
作者: Xuan Chen Michael Baron Department of Biostatistics and Programming Sanofi Beijing China Department of Mathematics and Statistics American University Washington DC USA Department of Mathematical Sciences University of Texas at Dallas Richardson USA
Effects of many medical procedures appear after a time lag, when a significant change occurs in subjects’ failure rate. This paper focuses on the detection and estimation of such changes which is important for the ev... 详细信息
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Robust Model Selection and Estimation for Censored Survival Data with High Dimensional Genomic Covariates
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Acta biotheoretica 2019年 第3期67卷 225-251页
作者: Guorong Chen Sijian Wang Guannan Sun Huanxue Pan Department of Finance Beijing Forestry University Beijing China. Department of Statistics and Biostatistics Rutgers University New Brunswick NJ USA. Department of Biostatistics and Programming Sanofi China Beijing China. Department of Finance Beijing Forestry University Beijing China. hxpbjfu@***.
When relating genomic data to survival outcomes, there are three main challenges that are the censored survival outcomes, the high-dimensionality of the genomic data, and the non-normality of data. We propose a method... 详细信息
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Performance evaluation of practice courses using fuzzy cognitive maps
Performance evaluation of practice courses using fuzzy cogni...
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International Conference on Information Technology Based Higher Education and Training, ITHET
作者: Ahmet Albayrak Muammer Albayrak Department of Computer Programming Karadeniz Technical University Trabzon Turkey Department of Biostatistics and Medical Informatics Karadeniz Technical University Trabzon Turkey
In this study, the effect of practical courses (especially robotics) on students' success is evaluated using fuzzy cognitive maps. This study particularly focuses on how practical courses increase the learning ach... 详细信息
来源: 评论