The study of supply chains is important because manufacturing industries face an increasingly complex, global, and competitive environment. As present-day supply chains involve numerous heterogeneous entities with dif...
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ISBN:
(纸本)9781424468874
The study of supply chains is important because manufacturing industries face an increasingly complex, global, and competitive environment. As present-day supply chains involve numerous heterogeneous entities with different roles and dynamics, managing them is not straightforward. Hence, a simulation model can serve as a valuable quantitative tool that aids in decision-making. In this paper, we present an agent-based model of a global specialty chemicals supply chain. The model explicitly considers the various supply chain entities: upstream raw material suppliers, downstream customers as well as the internal entities of the specialty chemicals company. These internal entities include a centralized sales department and a number of production sites located at different regions in the world. Each production site has its own procurement, scheduling, storage, operations, and packaging departments. Each of these entities is represented by an agent, each with its own goals and tasks, following the belief-desire-intention formalism. The model has been implemented in Jadex and simulates various supply chain activities such as raw material procurement, order assignment, job scheduling, storage, and production. It allows the user to simulate and analyze different supply chain policies, configurations, and uncertainties. This paper describes the model and illustrates its capabilities for decision support.
In attempts to modify the degradation characteristics of polylactic acid (PLA) the addition of selected low molecular weight (MW) ionic liquids, at concentrations up to 5 wt%, are shown to result in enhanced thermal a...
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ISBN:
(纸本)9781605603209
In attempts to modify the degradation characteristics of polylactic acid (PLA) the addition of selected low molecular weight (MW) ionic liquids, at concentrations up to 5 wt%, are shown to result in enhanced thermal and hydrolytic degradation rates accompanied by plasticization and lubrication. Thermal degradation was studied via mass changes, MW changes by gel-permeation chromatography and viscosity changes, whereas hydrolytic degradation was followed by MW changes, scanning electron microscopy, solution pH and acid number changes and visual observations. The different effects of the two ionic liquids are explained in terms of their different chemical structures and interactions with the polymer.
Background: The quest toward an artificial β-cell has been accelerating, propelled by recent technological advances in subcutaneous glucose sensors and insulin pumps. The development and clinical testing of algorithm...
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Surface plasmon resonance (SPR) has provided sensitive and label-free solution to detecting molecular interactions. We investigated the sensitivity enhancement of SPR based on plasmonic coupling in metallic nanostruct...
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In summary, a new biodegradable cell-based device has been developed based on the integration of two techniques: microcapsules and surface coated PCL capsule. Microcapsules provide a 3-D microenvironment for spatial c...
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ISBN:
(纸本)9780816910502
In summary, a new biodegradable cell-based device has been developed based on the integration of two techniques: microcapsules and surface coated PCL capsule. Microcapsules provide a 3-D microenvironment for spatial cell growth with good viability and proliferation. Coating biocompatible and hydrophilic PEG gelatin on the PCL surface could mediate the inflammatory response, minimize the fibrosis formation, and maintain the release performance. Our ongoing work is to test AP and PCL nanoporous membrane immunoprotection and controlled release functions for therapeutic cell secreting products. Hopefully, the dual nanoporous construct provides a unique way to allow superior cell growth, immuoprotection, fibrosis prevention and controllable release of secreted product in a biodegradable device.
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