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arXiv 2022年

作者： Lewis, Laura Zhu, Daiwei Gheorghiu, Alexandru Noel, Crystal Katz, Or Harraz, Bahaa Wang, Qingfeng Risinger, Andrew Feng, Lei Biswas, Debopriyo Egan, Laird Vidick, Thomas Cetina, Marko Monroe, Christopher Institute for Quantum Information and Matter Department of Computing and Mathematical Sciences California Institute of Technology CA91125 United States Division of Physics Mathematics and Astronomy California Institute of Technology CA91125 United States Joint Quantum Institute Departments of Physics and Electrical and Computer Engineering University of Maryland College ParkMD20742 United States Joint Center for Quantum Information and Computer Science NIST University of Maryland College ParkMD20742 United States IonQ Inc. College ParkMD20740 United States Departments of Electrical and Computer Engineering University of Maryland College ParkMD20742 United States Institute for Theoretical Studies ETH Zürich CH 8001 Switzerland Duke Quantum Center Department of Physics Duke University DurhamNC27708 United States Department of Electrical and Computer Engineering Duke University DurhamNC27708 United States Chemical Physics Program Institute for Physical Science and Technology University of Maryland College ParkMD20742 United States

A test of quantumness is a protocol where a classical user issues challenges to a quantum device to determine if it exhibits non-classical behavior, under certain cryptographic assumptions. Recent attempts to implement such tests on current quantum computers rely on either interactive challenges with efficient verification, or non-interactive challenges with inefficient (exponential time) verification. In this paper, we execute an efficient non-interactive test of quantumness on an ion-trap quantum computer. Our results significantly exceed the bound for a classical device’s success. Copyright © 2022, The Authors. All rights reserved.

关键词： Qubits

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Coulomb interaction-driven reshaped weyl fermionic dispersions in MoTe2

arXiv

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arXiv 2021年

作者： Kang, Seoung-Hun Jeon, Sangjun Kim, Hyun-Jung Ko, Wonhee Cho, Suyeon Kang, Se Hwang Kim, Sung Wng Yang, Heejun Kim, Hyo Won Son, Young-Woo Korea Institute for Advanced Study Seoul02455 Korea Republic of Department of Physics Chung-Ang University Seoul06974 Korea Republic of Peter Grünberg Institute Institute for Advanced Simulation Forschungszentrum Jülich Jülich52428 Germany Samsung Advanced Institute of Technology Suwon16678 Korea Republic of Center for Nanophase Materials Sciences Oak Ridge National Laboratory Oak RidgeTN37831 United States Department of Chemical Engineering and Materials Science Graduate Program in System Health Science and Engineering Ewha Womans University Seoul03760 Korea Republic of Department of Energy Science Sungkyunkwan University Suwon16419 Korea Republic of Department of Physics Korea Advanced Institute of Science and Technology Daejeon34141 Korea Republic of

We report the direct evidence of impacts of the Coulomb interaction in a prototypical Weyl semimetal, MoTe2, that alter its bare bands in a wide range of energy and momentum. Our quasiparticle interference patterns measured using scanning tunneling microscopy are shown to match the joint density of states of quasiparticle energy bands including momentum-dependent self-energy corrections, while electronic energy bands based on the other simpler local approximations of the Coulomb interaction fail to explain neither the correct number of quasiparticle pockets nor shape of their dispersions observed in our spectrum. With this, we predict a transition between type-I and type-II Weyl fermions with doping and resolve its disparate quantum oscillation experiments, thus highlighting the critical roles of Coulomb interactions in layered Weyl semimetals. © 2021, CC BY-NC-ND.

关键词： Dispersions

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Correction to: The formation of new (Al, Zn)3Zr precipitates in an Al–Zn–Mg–Cu aluminum alloy after aging treatment and their response to dynamic compression

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Archives of Civil and Mechanical engineering 2022年第1期23卷 1-1页

作者： Khan, Muhammad Abubaker Wang, Yangwei Afifi, Mohamed A. Tabish, Mohammad Hamza, Muhammad Yasin, Ghulam Ahmad, Tahir Liao, Wei-Bing College of Physics and Optoelectronic Engineering Shenzhen University Shenzhen China School of Materials Science and Engineering Beijing Institute of Technology Beijing China Mechanical Engineering Program School of Engineering and Applied Sciences Nile University Giza Egypt Smart Engineering Systems Research Centre (SESC) Nile University Giza Egypt School of Materials Science and Engineering Beijing University of Chemical Technology Beijing China Institute of Advanced Materials Bahauddin Zakariya University Multan Pakistan Department of Metallurgy and Materials Engineering College of Engineering and Emerging Technologies University of the Punjab Lahore Pakistan

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Prediction of Fluctuations in a Chaotic Cancer Model Using Machine Learning

SSRN

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SSRN 2022年

作者： Sayari, Elaheh da Silva, Sidney Tiago Iarosz, Kelly C. Viana, Ricardo L. Szezech, José Danilo Batista, Antonio Marcos Post-Graduation in Science State University of Ponta Grossa PR Ponta Grossa Brazil Federal University of Paraná PR Curitiba Brazil Faculdade de Telêmaco Borba FATEB Telêmaco Borba Paraná Brazil Graduate Program in Chemical Engineering Federal Technological University of Paraná PR Ponta Grossa Brazil Department of Physics Federal University of Paraná PR Curitiba Brazil Institute of Physics University of São Paulo SP São Paulo Brazil Mathematics and Statistics Department State University of Ponta Grossa PR Ponta Grossa Brazil

Cancer is a group of diseases and the second leading cause of death according to World Health Organization. Mathematical and computational methods have been used to explore the cancer cells spread and the mechanism of their growth. We study a cancer model that exhibits both periodic and chaotic attractors. It describes the interactions among host, effector immune, and cancer cells. It is observed fluctuations in the population of cells. The fluctuation range can be associated with the appearance of tumour cells. In this work, we use machine learning algorithms for the prediction of fluctuations. We show that our machine learning classification is able to identify fluctuations that are associated with the growth rate of cancer cells. © 2022, The Authors. All rights reserved.

关键词： Cancer cells

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Machine-learned molecular mechanics force field for the simulation of protein-ligand systems and beyond

arXiv

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arXiv 2023年

作者： Takaba, Kenichiro Pulido, Iván Behara, Pavan Kumar Cavender, Chapin E. Friedman, Anika J. Henry, Michael M. MacDermott-Opeskin, Hugo Iacovella, Christopher R. Nagle, Arnav M. Payne, Alexander Matthew Shirts, Michael R. Mobley, David L. Chodera, John D. Wang, Yuanqing Computational and Systems Biology Program Sloan Kettering Institute Memorial Sloan Kettering Cancer Center New YorkNY10065 United States Pharmaceuticals Research Center Advanced Drug Discovery Asahi Kasei Pharma Corporation Shizuoka410-2321 Japan Center for Neurotherapeutics Department of Pathology and Laboratory Medicine University of California IrvineCA92697 United States Skaggs School of Pharmacy and Pharmaceutical Sciences University of California 9500 Gilman Drive La Jolla San DiegoCA92093 United States Department of Chemical and Biological Engineering University of Colorado Boulder BoulderCO80309 United States Open Molecular Software Foundation DavisCA95618 United States Department of Bioengineering University of California Berkeley BerkeleyCA94720 United States Department of Pharmaceutical Sciences University of California IrvineCA92697 United States Tri-Institutional Ph.D. Program in Chemical Biology Memorial Sloan Kettering Cancer Center New YorkNY10065 United States Simons Center for Computational Physical Chemistry Center for Data Science New York University New YorkNY10004 United States

The development of reliable and extensible molecular mechanics (MM) force fields—fast, empirical models characterizing the potential energy surface of molecular systems—is indispensable for biomolecular simulation and computer-aided drug design. Here, we introduce a generalized and extensible machine-learned MM force field, espaloma-0.3, and an end-to-end differentiable framework using graph neural networks to overcome the limitations of traditional rule-based methods. Trained in a single GPU-day to fit a large and diverse quantum chemical dataset of over 1.1M energy and force calculations, espaloma-0.3 reproduces quantum chemical energetic properties of chemical domains highly relevant to drug discovery, including small molecules, peptides, and nucleic acids. Moreover, this force field maintains the quantum chemical energy-minimized geometries of small molecules and preserves the condensed phase properties of peptides, self-consistently parametrizing proteins and ligands to produce stable simulations leading to highly accurate predictions of binding free energies. This methodology demonstrates significant promise as a path forward for systematically building more accurate force fields that are easily extensible to new chemical domains of interest. © 2023, CC BY.

关键词： Quantum chemistry

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Room-temperature polar metal stabilized under high pressure

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Physical Review B 2020年第22期101卷 220101(R)-220101(R)页

作者： J.-J. Gao S.-Y. Fu K. Yamaura J. F. Lin J.-S. Zhou Materials Science and Engineering Program Mechanical Engineering The University of Texas at Austin Austin Texas 78712 USA Institute of Fluid Physics China Academy of Engineering Physics Mianyang 621900 China Department of Geological Sciences The University of Texas at Austin Austin Texas 78712 USA International Center for Materials Nanoarchitectronics (WPI-MANA) National Institute for Materials Science 1-1 Namiki Tsukuba Ibaraki 305-0044 Japan Graduate School of Chemical Sciences and Engineering Hokkaido University North 10 West 8 Kita-ku Sapporo Hokkaido 060-0810 Japan

LiOsO3 synthesized under high pressure in recent years is a rare metal since it undergoes a nonpolar to polar phase transition at Ts=140K. Forming a polar axis through a phase transition in a metal seems against common sense. It is also not clear whether the transition to a polar phase in the oxide fits the mechanism predicted by Anderson and Blount in 1965. As monitored by an anomaly of resistivity in LiOsO3 at Ts reported recently, Ts increases under pressure. The structural study under high pressure could give us a useful clue for understanding how dipoles form in this metallic oxide. Here, we report the identification of a polar phase of LiOsO3 at room temperature under high pressure by using in situ probes of Raman and synchrotron x-ray diffraction. In the Raman study, the pressure-induced modes and their responses to polarized light, the linewidth change, the peak profile change, and mode softening have been directly compared with the corresponding changes of LiOsO3 on cooling through Ts at ambient pressure. Whereas a complete set of Raman modes from the R3c phase can be found at P≥15.5GPa, a Raman mode of the R3c phase appears in the R3¯c phase at 4.11 GPa. A significant drop in the linewidth occurs at 12.6 GPa that coincides with the critical pressure for the phase transition to the polar phase detected by x-ray diffraction. Fitting the peak profile of a Raman mode to the Fano formula also indicates a clear change of electron-phonon coupling at 16 GPa. In contrast to a sharp structural transition to the polar phase at Ts under ambient pressure, our results reveal all the structural ingredients to facilitate the polar phase over a broad range of pressure. A bond valence sum analysis has been introduced to reveal the local structural instability under pressure. The transition to the polar phase in metallic LiOsO3 is solely caused by optimizing the local structure in order to make the bond valence sum close to the formal valence of the Li ion.

关键词： Ferroelectricity Phase transitions Pressure effects Metals

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Migration and Precipitation of Platinum in Anion-Exchange Membrane Fuel Cells

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Angewandte Chemie 2023年第37期135卷

作者： Aniket Raut Haoyan Fang Yu-Chung Lin Shi Fu David Sprouster Ryuichi Shimogawa Anatoly I. Frenkel Chulsung Bae John C. Douglin Jaana Lillojad Kaido Tammeveski Zhiqiao Zeng Stoyan Bliznakov Miriam Rafailovich Dario R. Dekel Department of Materials Science and Chemical Engineering State University of New York at Stony Brook Stony Brook NY 11794 USA Mitsubishi Chemical Corporation Science & Innovation Center 1000 Kamoshida-cho Aoba-ku Yokohama 227–8502 Japan Division of Chemistry Brookhaven National Laboratory Upton NY 11973 USA Department of Chemistry and Chemical Biology Rensselaer Polytechnic Institute Troy NY 12180 USA The Wolfson Department of Chemical Engineering Technion—Israel Institute of Technology Haifa 3200003 (Israel) Institute of Chemistry University of Tartu Ravila 14a 50411 Tartu Estonia Center for Clean Energy Engineering University of Connecticut Storrs CT 06269 USA The Nancy & Stephen Grand Technion Energy Program (GTEP) Technion—Israel Institute of Technology Haifa 3200003 Israel

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ARSENIC HASTENS THE ONSET OF OSTEOARTHRITIS BY TRIGGERING THE NF-κB-HIF-2α/ZIP8 SIGNALING PATHWAY VIA REACTIVE OXYGEN SPECIES

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Osteoarthritis and Cartilage 2024年 32卷 S430-S430页

作者： Gamaarachchige, Dinesh Suminda Godagama Min, Yunhui Heo, Yunji Lee, Juyeon Jung, Man-Young GHOSH, MRINMOY Son, Young-Ok Interdisciplinary Graduate Program in Advanced Convergence Technology and Science Jeju National University Jeju Korea (the Republic of) Department of Animal Biotechnology Faculty of Biotechnology Jeju National University Jeju Korea (the Republic of) Department of Biology Education Jeju National University Jeju Korea (the Republic of) Department of Biotechnology School of Bio Chemical and Processing Engineering (SBCE) Kalasalin-gam Academy of Research and Educational Krishnankoil Tamil Nadu India

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The Real Time Analysis framework of the Cherenkov Telescope Array’s Large-Sized Telescope 38

The Real Time Analysis framework of the Cherenkov Telescope ...

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38th International Cosmic Ray Conference, ICRC 2023

作者： Caroff, Sami Aubert, Pierre Garcia, Enrique Maurin, Gilles Pollet, Vincent Vuillaume, Thomas Abe, K. Abe, S. Aguasca-Cabot, A. Agudo, I. Alvarez Crespo, N. Antonelli, L.A. Aramo, C. Arbet-Engels, A. Arcaro, C. Artero, M. Asano, K. Aubert, P. Baktash, A. Bamba, A. Baquero Larriva, A. Baroncelli, L. Barres de Almeida, U. Barrio, J.A. Batkovic, I. Baxter, J. Becerra González, J. Bernardini, E. Bernardos, M.I. Bernete Medrano, J. Berti, A. Bhattacharjee, P. Biederbeck, N. Bigongiari, C. Bissaldi, E. Blanch, O. Bonnoli, G. Bordas, P. Bulgarelli, A. Burelli, I. Burmistrov, L. Buscemi, M. Cardillo, M. Caroff, S. Carosi, A. Carrasco, M.S. Cassol, F. Cauz, D. Cerasole, D. Ceribella, G. Chai, Y. Cheng, K. Chiavassa, A. Chikawa, M. Chytka, L. Cifuentes, A. Contreras, J.L. Cortina, J. Costantini, H. Dalchenko, M. Dazzi, F. De Angelis, A. de Bony de Lavergne, M. De Lotto, B. De Lucia, M. de Menezes, R. Del Peral, L. Deleglise, G. Delgado, C. Delgado Mengual, J. della Volpe, D. Dellaiera, M. Di Piano, A. Di Pierro, F. Di Pilato, A. Di Tria, R. Di Venere, L. Díaz, C. Dominik, R.M. Dominis Prester, D. Donini, A. Dorner, D. Doro, M. Eisenberger, L. Elsässer, D. Emery, G. Escudero, J. Fallah Ramazani, V. Ferrara, G. Ferrarotto, F. Fiasson, A. Foffano, L. Freixas Coromina, L. Fröse, S. Fukami, S. Fukazawa, Y. Garcia, E. Garcia López, R. Gasbarra, C. Gasparrini, D. Geyer, D. Giesbrecht Paiva, J. Giglietto, N. Giordano, F. Gliwny, P. Godinovic, N. Grau, R. Green, J. Green, D. Gunji, S. Günther, P. Hackfeld, J. Hadasch, D. Hahn, A. Hashiyama, K. Hassan, T. Hayashi, K. Heckmann, L. Heller, M. Herrera Llorente, J. Hirotani, K. Hoffmann, D. Horns, D. Houles, J. Hrabovsky, M. Hrupec, D. Hui, D. Hütten, M. Iarlori, M. Imazawa, R. Inada, T. Inome, Y. Ioka, K. Iori, M. Ishio, K. Jimenez Martinez, I. Jurysek, J. Kagaya, M. Karas, V. Katagiri, H. Kataoka, J. Kerszberg, D. Kobayashi, Y. Kohri, K. Kong, A. Kubo, H. Kushida, J. Lainez, M. Lamanna, G. Lamastra, A. Le Flour, T. Linhoff, M. Longo, F. Univ. Savoie Mont Blanc CNRS Laboratoire d’Annecy de Physique des Particules IN2P3 Annecy74000 France Department of Physics Tokai University Japan Institute for Cosmic Ray Research University of Tokyo Japan Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Spain Instituto de Astrofísica de Andalucía-CSIC Spain EMFTEL department IPARCOS Universidad Complutense de Madrid Spain INAF Osservatorio Astronomico di Roma Italy INFN Sezione di Napoli Italy Max-Planck-Institut für Physik Germany INFN Sezione di Padova Università degli Studi di Padova Italy The Barcelona Institute of Science and Technology Spain LAPP Univ. Grenoble Alpes Univ. Savoie Mont Blanc CNRS IN2P3 Annecy France Universität Hamburg Institut für Experimentalphysik Germany Graduate School of Science University of Tokyo Japan Universidad del Azuay Ecuador INAF Osservatorio di Astrofisica e Scienza dello spazio di Bologna Italy Centro Brasileiro de Pesquisas Físicas Brazil Instituto de Astrofísica de Canarias Departamento de Astrofísica Universidad de La Laguna Spain CIEMAT Spain Department of Physics TU Dortmund University Germany INFN Sezione di Bari Politecnico di Bari Italy INAF Osservatorio Astronomico di Brera Italy INFN Sezione di Trieste Università degli Studi di Udine Italy University of Geneva Département de physique nucléaire et corpusculaire Switzerland INFN Sezione di Catania Italy Italy Aix Marseille Univ CNRS IN2P3 CPPM France INFN Sezione di Bari Università di Bari Italy INFN Sezione di Torino Italy Palacky University Olomouc Faculty of Science Czech Republic University of Alcalá UAH Spain Port d’Informació Científica Spain University of Rijeka Department of Physics Croatia Institute for Theoretical Physics and Astrophysics Universität Würzburg Germany Institut für Theoretische Physik Lehrstuhl IV: Plasma-Astroteilchenphysik Ruhr-Universität Bochum Germany INFN Sezione di Roma La Sapienza Italy ILANCE

The Large-Sized Telescopes (LSTs) of the Cherenkov Telescope Array Observatory (CTAO) will play a crucial role in the study of transient gamma-ray sources, such as gamma-ray bursts and flaring active galactic nuclei. The low energy threshold of LSTs makes them particularly well suited for the detection of these phenomena. The ability to detect and analyze gamma-ray transients in real-time is essential for quickly identifying and studying these rare and fleeting events. In this conference, we will present recent advances in the real-time analysis of data from the LST-1, the first prototype of LST located in the Canary island of La Palma. We will discuss in particular the development of new algorithms for event reconstruction and background rejection. These advances will enable rapid identification and follow-up observation of transient gamma-ray sources, making the LST-1 a powerful tool for the study of the dynamic universe. The implementation of this framework in the future Array Control and Data Acquisition System (ACADA) of CTAO will be discussed as well, based on the experience with LST. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Cosmology

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First results of pulsar observations with the LST-1 38

First results of pulsar observations with the LST-1

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38th International Cosmic Ray Conference, ICRC 2023

作者： Mas-Aguilar, Álvaro Brunelli, Giulia Ceribella, Giovanni López-Moya, Marcos López-Coto, Rubén Abe, K. Abe, S. Aguasca-Cabot, A. Agudo, I. Alvarez Crespo, N. Antonelli, L.A. Aramo, C. Arbet-Engels, A. Arcaro, C. Artero, M. Asano, K. Aubert, P. Baktash, A. Bamba, A. Baquero Larriva, A. Baroncelli, L. Barres de Almeida, U. Barrio, J.A. Batkovic, I. Baxter, J. Becerra González, J. Bernardini, E. Bernardos, M.I. Bernete Medrano, J. Berti, A. Bhattacharjee, P. Biederbeck, N. Bigongiari, C. Bissaldi, E. Blanch, O. Bonnoli, G. Bordas, P. Brunelli, G. Bulgarelli, A. Burelli, I. Burmistrov, L. Buscemi, M. Cardillo, M. Caroff, S. Carosi, A. Carrasco, M.S. Cassol, F. Cauz, D. Cerasole, D. Ceribella, G. Chai, Y. Cheng, K. Chiavassa, A. Chikawa, M. Chytka, L. Cifuentes, A. Contreras, J.L. Cortina, J. Costantini, H. Dalchenko, M. Dazzi, F. De Angelis, A. de Bony de Lavergne, M. De Lotto, B. De Lucia, M. de Menezes, R. Del Peral, L. Deleglise, G. Delgado, C. Delgado Mengual, J. della Volpe, D. Dellaiera, M. Di Piano, A. Di Pierro, F. Di Pilato, A. Di Tria, R. Di Venere, L. Díaz, C. Dominik, R.M. Dominis Prester, D. Donini, A. Dorner, D. Doro, M. Eisenberger, L. Elsässer, D. Emery, G. Escudero, J. Fallah Ramazani, V. Ferrara, G. Ferrarotto, F. Fiasson, A. Foffano, L. Freixas Coromina, L. Fröse, S. Fukami, S. Fukazawa, Y. Garcia, E. Garcia López, R. Gasbarra, C. Gasparrini, D. Geyer, D. Giesbrecht Paiva, J. Giglietto, N. Giordano, F. Gliwny, P. Godinovic, N. Grau, R. Green, J. Green, D. Gunji, S. Günther, P. Hackfeld, J. Hadasch, D. Hahn, A. Hashiyama, K. Hassan, T. Hayashi, K. Heckmann, L. Heller, M. Herrera Llorente, J. Hirotani, K. Hoffmann, D. Horns, D. Houles, J. Hrabovsky, M. Hrupec, D. Hui, D. Hütten, M. Iarlori, M. Imazawa, R. Inada, T. Inome, Y. Ioka, K. Iori, M. Ishio, K. Jimenez Martinez, I. Jurysek, J. Kagaya, M. Karas, V. Katagiri, H. Kataoka, J. Kerszberg, D. Kobayashi, Y. Kohri, K. Kong, A. Kubo, H. Kushida, J. Lainez, M. Lamanna, G. Lamastra, A. IPARCOS Department of EMFTEL Universidad Complutense de Madrid MadridE-28040 Spain INAF-OAS Università di Bologna Bologna40129 Italy Instituto de Astrofísica de Andalucía-CSIC Glorieta de la Astronomía s/n Granada18008 Spain Max-Planck-Institut for Physics Munich80805 Germany Department of Physics Tokai University Japan Institute for Cosmic Ray Research University of Tokyo Japan Departament de Física Quàntica i Astrofísica Institut de Ciències del Cosmos Universitat de Barcelona IEEC-UB Spain INAF Osservatorio Astronomico di Roma Italy INFN Sezione di Napoli Italy Max-Planck-Institut für Physik Germany INFN Sezione di Padova Università degli Studi di Padova Italy The Barcelona Institute of Science and Technology Spain LAPP Univ. Grenoble Alpes Univ. Savoie Mont Blanc CNRS-IN2P3 Annecy France Universität Hamburg Institut für Experimentalphysik Germany Graduate School of Science University of Tokyo Japan Universidad del Azuay Ecuador INAF Osservatorio di Astrofisica e Scienza dello spazio di Bologna Italy Centro Brasileiro de Pesquisas Físicas Brazil Instituto de Astrofísica de Canarias Departamento de Astrofísica Universidad de La Laguna Spain CIEMAT Spain Department of Physics TU Dortmund University Germany INFN Sezione di Bari Politecnico di Bari Italy INAF Osservatorio Astronomico di Brera Italy INFN Sezione di Trieste Università degli Studi di Udine Italy University of Geneva Département de physique nucléaire et corpusculaire Switzerland INFN Sezione di Catania Italy Italy Aix Marseille Univ CNRS IN2P3 CPPM France INFN Sezione di Bari Università di Bari Italy INFN Sezione di Torino Italy Palacky University Olomouc Faculty of Science Czech Republic University of Alcalá UAH Spain Port d’Informació Científica Spain University of Rijeka Department of Physics Croatia Institute for Theoretical Physics and Astrophysics Universität Würzburg Germany Institut für Theoretische Physik Lehrstuhl IV: Plasma-Astroteilchenphysik Ruhr-Universität B

After the discovery of Crab, Vela, and Geminga pulsars at Very High Energies, the search for new pulsars at tens of GeV has been gaining huge importance. However, their steep spectra along with the sensitivity of the current generation of Imaging Atmospheric Cherenkov telescopes (IACTs) are limiting the capability to detect more pulsars. The LST-1 is the first prototype of the Large-Sized Telescope of the forthcoming CTA observatory with enhanced sensitivity at tens of GeV. The LST-1 started its commissioning phase in 2018, and since then it has observed the Crab pulsar regularly. Here, we show the first results of the analysis of the Crab and other pulsars taken with the LST-1. The two characteristic emission peaks of the Crab pulsar, P1, and P2, are detected with high significance showing a clear improvement in sensitivity over the previous generation of IACTs. The spectrum is reconstructed up to 450 GeV for P1 and up to 700 GeV for P2. The low energy threshold of LST-1 also allows us to measure the spectrum of the Crab pulsar in the overlapping region with the Fermi-LAT and cross-calibrate both instruments. The results obtained with the first pulsar observations with the LST-1 confirm the excellent potential of LST telescopes to study and discover new pulsars in the near future. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Shellfish

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