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Author Correction: Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

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Nature communications 2021年第1期12卷 415页

作者： Yeon Sik Choi Yuan-Yu Hsueh Jahyun Koo Quansan Yang Raudel Avila Buwei Hu Zhaoqian Xie Geumbee Lee Zheng Ning Claire Liu Yameng Xu Young Joong Lee Weikang Zhao Jun Fang Yujun Deng Seung Min Lee Abraham Vázquez-Guardado Iwona Stepien Ying Yan Joseph W Song Chad Haney Yong Suk Oh Wentai Liu Hong-Joon Yoon Anthony Banks Matthew R MacEwan Guillermo A Ameer Wilson Z Ray Yonggang Huang Tao Xie Colin K Franz Song Li John A Rogers Center for Bio-Integrated Electronics Northwestern University Evanston IL 60208 USA. Querrey Simpson Institute for Biotechnology Northwestern University Evanston IL 60208 USA. Department of Materials Science and Engineering Northwestern University Evanston IL 60208 USA. Department of Bioengineering University of California Los Angeles Los Angeles CA 90095 USA. Division of Plastic and Reconstructive Surgery Department of Surgery National Cheng Kung University Hospital College of Medicine National Cheng Kung University Tainan 70456 Taiwan. International Research Center for Wound Repair and Regeneration National Cheng Kung University Tainan 70456 Taiwan. School of Biomedical Engineering Korea University Seoul 02841 Republic of Korea. Interdisciplinary Program in Precision Public Health Korea University Seoul 02841 Republic of Korea. Department of Mechanical Engineering Northwestern University Evanston IL 60208 USA. Department of Medicine University of California Los Angeles Los Angeles CA 90095 USA. State Key Laboratory of Structural Analysis for Industrial Equipment Dalian University of Technology 116024 Dalian China. Department of Engineering Mechanics Dalian University of Technology 116024 Dalian China. International Research Center for Computational Mechanics Dalian University of Technology 116024 Dalian China. State Key Laboratory of Chemical Engineering College of Chemical and Biological Engineering Zhejiang University 310027 Hangzhou China. Department of Biomedical Engineering Northwestern University Evanston IL 60208 USA. State Key Laboratory of Mechanical System and Vibration Shanghai Jiao Tong University 200240 Shanghai China. Center for Developmental Therapeutics Chemistry Life Processes Institute Northwestern University Evanston IL 60208 USA. Department of Neurological Surgery Washington University School of Medicine St. Louis MO 63110 USA. Center for Advanced Molecular Imaging Northwestern University Evanston IL

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An Artificial Phase-Transitional Underwater Bioglue with Robust and Switchable Adhesion Performance

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Angewandte Chemie 2021年第21期133卷

作者： Lingling Xiao Zili Wang Yao Sun Bo Li Baiheng Wu Chao Ma Vladislav S. Petrovskii Xinquan Gu Dong Chen Igor I. Potemkin Andreas Herrmann Hongjie Zhang Kai Liu State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun 130022 China University of Science and Technology of China Hefei 230026 China Department of Chemistry Tsinghua University Beijing 100084 China Department of Urology China-Japan Union Hospital of Jilin University Changchun 130022 China Institute of Process Equipment College of Energy Engineering Zhejiang University Hangzhou 310027 China School of Engineering and Applied Sciences Harvard University 29 Oxford Street Cambridge MA 02138 USA Physics Department Lomonosov Moscow State University Moscow 119991 Russian Federation Semenov Federal Research Center for Chemical Physics Russian Academy of Sciences 119991 Moscow Russian Federation National Research South Ural State University 454080 Chelyabinsk Russian Federation DWI—Leibniz Institute for Interactive Materials Forckenbeckstr. 50 52056 Aachen Germany Institute of Technical and Macromolecular Chemistry RWTH Aachen University Worringerweg 1 52074 Aachen Germany

Complex coacervation enables important wet adhesion processes in natural and artificial systems. However, existed synthetic coacervate adhesives show limited wet adhesion properties, non-thermoresponsiveness, and inferior biodegradability, greatly hampering their translations. Herein, by harnessing supramolecular assembly and rational protein design, we present a temperature-sensitive wet bioadhesive fabricated through recombinant protein and surfactant. Mechanical performance of the bioglue system is actively tunable with thermal triggers. In cold condition, adhesion strength of the bioadhesive was only about 50 kPa. By increasing temperature, the strength presented up to 600 kPa, which is remarkably stronger than other biological counterparts. This is probably due to the thermally triggered phase transition of the engineered protein and the formation of coacervate, thus leading to the enhanced wet adhesion bonding.

关键词： bioadhesion coacervate phase transitions protein engineering thermo-responsiveness

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Physical Characteristics of Modified Cassava Flour Wastewater at Room Temperature

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IOP Conference Series: Earth and Environmental science 2019年第1期292卷

作者： N Yaqin A N Al-Baarri A M Legowo Widayat M A Budihardjo Program of Environmental Science School of Post Graduate Studies Diponegoro University Semarang Indonesia Center of Research and Services-Diponegoro University Semarang Indonesia Food Technology Department Faculty of Animal and Agricultural Sciences Diponegoro University Semarang Indonesia Chemical Engineering Department Faculty of Engineering Diponegoro University Semarang Indonesia Department of Environmental Engineering Faculty of Engineering Diponegoro University Indonesia

Cassava is an agricultural material that is considered as important raw resources in the industrial sector. The benefits are even greater after being modified using lactic acid bacteria. However, the mocaf industry often causes water and air pollution. Environmental problems arise after the fermentation process. Determination problems with lightness, TDS (Total Dissolved Solid), conductivity and pH analysis are required to measure the impact to the environment. This research was used waste water from mocaf during 3 days fermentation. The wastewater had the highest color level (Lightness) on initial day of fermentation at 83.7±3.73 and then decrease along the day of fermentation at the averages of 65.2±2.0. The highest TDS was resulted from the mocaf wastewater at a value of 1218 ± 4.6 ppm which continued to decline until day 4. The conductivity and pH showed a decrease along the day of fermentation. As conclusion, physical characteristic of wastewater from mocaf production could be analyzed specifically and determined through color, TDS, conductivity, and pH.

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Population of Merging Compact Binaries Inferred Using Gravitational Waves through GWTC-3

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Physical Review X 2023年第1期13卷 011048-011048页

作者： R. Abbott T. D. Abbott F. Acernese K. Ackley C. Adams N. Adhikari R. X. Adhikari V. B. Adya C. Affeldt D. Agarwal M. Agathos K. Agatsuma N. Aggarwal O. D. Aguiar L. Aiello A. Ain P. Ajith T. Akutsu P. F. de Alarcón S. Akcay S. Albanesi A. Allocca P. A. Altin A. Amato C. Anand S. Anand A. Ananyeva S. B. Anderson W. G. Anderson M. Ando T. Andrade N. Andres T. Andrić S. V. Angelova S. Ansoldi J. M. Antelis S. Antier F. Antonini S. Appert Koji Arai Koya Arai Y. Arai S. Araki A. Araya M. C. Araya J. S. Areeda M. Arène N. Aritomi N. Arnaud M. Arogeti S. M. Aronson K. G. Arun H. Asada Y. Asali G. Ashton Y. Aso M. Assiduo S. M. Aston P. Astone F. Aubin C. Austin S. Babak F. Badaracco M. K. M. Bader C. Badger S. Bae Y. Bae A. M. Baer S. Bagnasco Y. Bai L. Baiotti J. Baird R. Bajpai M. Ball G. Ballardin S. W. Ballmer A. Balsamo G. Baltus S. Banagiri D. Bankar J. C. Barayoga C. Barbieri B. C. Barish D. Barker P. Barneo F. Barone B. Barr L. Barsotti M. Barsuglia D. Barta J. Bartlett M. A. Barton I. Bartos R. Bassiri A. Basti M. Bawaj J. C. Bayley A. C. Baylor M. Bazzan B. Bécsy V. M. Bedakihale M. Bejger I. Belahcene V. Benedetto D. Beniwal T. F. Bennett J. D. Bentley M. BenYaala F. Bergamin B. K. Berger S. Bernuzzi C. P. L. Berry D. Bersanetti A. Bertolini J. Betzwieser D. Beveridge R. Bhandare U. Bhardwaj D. Bhattacharjee S. Bhaumik I. A. Bilenko G. Billingsley S. Bini R. Birney O. Birnholtz S. Biscans M. Bischi S. Biscoveanu A. Bisht B. Biswas M. Bitossi M.-A. Bizouard J. K. Blackburn C. D. Blair D. G. Blair R. M. Blair F. Bobba N. Bode M. Boer G. Bogaert M. Boldrini L. D. Bonavena F. Bondu E. Bonilla R. Bonnand P. Booker B. A. Boom R. Bork V. Boschi N. Bose S. Bose V. Bossilkov V. Boudart Y. Bouffanais A. Bozzi C. Bradaschia P. R. Brady A. Bramley A. Branch M. Branchesi J. Brandt J. E. Brau M. Breschi T. Briant J. H. Briggs A. Brillet M. Brinkmann P. Brockill A. F. Brooks J. Brooks D. D. Brown S. Brunett G. Bruno R. Bruntz J. Bryant T. Bulik H. J. Bulten A. Buonanno R. Buscicchio D. Buskulic C. Buy R. L. Byer L. Cadonati LIGO Laboratory California Institute of Technology Pasadena California 91125 USA Louisiana State University Baton Rouge Louisiana 70803 USA Dipartimento di Farmacia Università di Salerno I-84084 Fisciano Salerno Italy INFN Sezione di Napoli Complesso Universitario di Monte S. Angelo I-80126 Napoli Italy OzGrav School of Physics & Astronomy Monash University Clayton 3800 Victoria Australia LIGO Livingston Observatory Livingston Louisiana 70754 USA University of Wisconsin-Milwaukee Milwaukee Wisconsin 53201 USA OzGrav Australian National University Canberra Australian Capital Territory 0200 Australia Max Planck Institute for Gravitational Physics (Albert Einstein Institute) D-30167 Hannover Germany Leibniz Universität Hannover D-30167 Hannover Germany Inter-University Centre for Astronomy and Astrophysics Pune 411007 India University of Cambridge Cambridge CB2 1TN United Kingdom Theoretisch-Physikalisches Institut Friedrich-Schiller-Universität Jena D-07743 Jena Germany University of Birmingham Birmingham B15 2TT United Kingdom Center for Interdisciplinary Exploration & Research in Astrophysics (CIERA) Northwestern University Evanston Illinois 60208 USA Instituto Nacional de Pesquisas Espaciais 12227-010 São José dos Campos São Paulo Brazil Gravity Exploration Institute Cardiff University Cardiff CF24 3AA United Kingdom INFN Sezione di Pisa I-56127 Pisa Italy International Centre for Theoretical Sciences Tata Institute of Fundamental Research Bengaluru 560089 India Gravitational Wave Science Project National Astronomical Observatory of Japan (NAOJ) Mitaka City Tokyo 181-8588 Japan Advanced Technology Center National Astronomical Observatory of Japan (NAOJ) Mitaka City Tokyo 181-8588 Japan Universitat de les Illes Balears IAC3–IEEC E-07122 Palma de Mallorca Spain University College Dublin Dublin 4 Ireland INFN Sezione di Torino I-10125 Torino Italy Università di Napoli “Federico II” Complesso Universitario di Monte S. Angelo I-80126 Napoli

We report on the population properties of compact binary mergers inferred from gravitational-wave observations of these systems during the first three LIGO-Virgo observing runs. The Gravitational-Wave Transient Catalog 3 (GWTC-3) contains signals consistent with three classes of binary mergers: binary black hole, binary neutron star, and neutron star–black hole mergers. We infer the binary neutron star merger rate to be between 10 and 1700 Gpc−3 yr−1 and the neutron star–black hole merger rate to be between 7.8 and 140 Gpc−3 yr−1, assuming a constant rate density in the comoving frame and taking the union of 90% credible intervals for methods used in this work. We infer the binary black hole merger rate, allowing for evolution with redshift, to be between 17.9 and 44 Gpc−3 yr−1 at a fiducial redshift (z=0.2). The rate of binary black hole mergers is observed to increase with redshift at a rate proportional to (1+z)κ with κ=2.9−1.8+1.7 for z≲1. Using both binary neutron star and neutron star–black hole binaries, we obtain a broad, relatively flat neutron star mass distribution extending from 1.2−0.2+0.1 to 2.0−0.3+0.3M⊙. We confidently determine that the merger rate as a function of mass sharply declines after the expected maximum neutron star mass, but cannot yet confirm or rule out the existence of a lower mass gap between neutron stars and black holes. We also find the binary black hole mass distribution has localized over- and underdensities relative to a power-law distribution, with peaks emerging at chirp masses of 8.3−0.5+0.3 and 27.9−1.8+1.9M⊙. While we continue to find that the mass distribution of a binary’s more massive component strongly decreases as a function of primary mass, we observe no evidence of a strongly suppressed merger rate above approximately 60M⊙, which would indicate the presence of a upper mass gap. Observed black hole spins are small, with half of spin magnitudes below χi≈0.25. While the majority of spins are preferentially aligned wi

关键词： Gravitational wave sources Gravitational waves Gravitational wave detection

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Enzyme Immobilization: Overcoming the Pitfalls of Cytochrome P450 Immobilization through the Use of Fusogenic Liposomes (Adv. Biosys. 1/2019)

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Advanced Biology 2019年第1期3卷

作者： Iiro M. A. Kiiski Tea Pihlaja Lauri Urvas Joanna Witos Susanne K. Wiedmer Ville P. Jokinen Tiina M. Sikanen Drug Research Program Division of Pharmaceutical Chemistry and Technology Faculty of Pharmacy P.O. Box 56 (Viikinkaari 5E) Helsinki FI-00014 Finland Department of Bioproducts and Biosystems School of Chemical Engineering Aalto University Aalto FI-00076 Finland Department of Chemistry Faculty of Science Helsinki FI-00014 Finland Department of Materials Science and Engineering School of Chemical Engineering Aalto University Espoo FI-02150 Finland

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Synthesis and Electrochromic Properties of Polyimides with Pendent Benzimidazole and Triphenylamine Units

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Chinese Journal of Polymer science 2016年第9期34卷 1091-1102页

作者： Wan-an Cai Ji-wei Cai 牛海军 Tian-di Xiao Xu-duo Bai Cheng Wang 张艳红 Wen Wang Key Laboratory of Functional Inorganic Material Chemistry Ministry of EducationDepartment of Macromolecular Science and EngineeringSchool of ChemicalChemical Engineering and MaterialsHeilongjiang UniversityHarbin 150086China School of Material Science and Engineering Harbin Institute of TechnologyHarbin 150080China

Five novel near-infrared electrochromic aromatic polyimides （PIs） with pendent benzimidazole group were synthesized from 4,4＇-diamino-4＂-（1-benzylbenzimidazol-2-yl）triphenylamine （named as DBBT） with five different dianhydrides via two-step polymerization process, respectively. The maximum UV-Vis absorption bands of these PIs locate at about 335 nm for solid films due to the π-π＊ transitions. A reversible pair of distinct redox peaks, that were associated with a noticeable color change from original yellow to blue, was observed in the cyclic voltammetry （CV） test. A new absorption peak emerged at 847 nm in near-infrared （NIR） region with increasing voltage in UV-Vis-NIR spectrum, which indicates that PI can be used as NIR electrochromic material. These novel PIs have good electrochemical stability, appropriate energy levels for the highest occupied molecular orbital （HOMO） and the lowest unoccupied molecular orbital （LUMO）, in the range of-5.17 eV to -5.20 eV and -2.14 eV to -2.26 eV （versus the vacuum level） determined by cyclic voltammetry method. These values basically consisted with the results of quantum chemical calculation. These polyimides can be used as novel electrochromic and hole transportation materials.

关键词： Triphenylamine Electrochromic Benzimidazole Polyimide Near-infrared.

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Effects of drug resistance in the tumour-immune system with chemotherapy treatment

arXiv

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arXiv 2020年

作者： Trobia, José Gabrick, Enrique C. Seifert, Evandro G. Borges, Fernando S. Protachevicz, Paulo R. Szezech, José D. Iarosz, Kelly C. Santos, Moises S. Caldas, Iberê L. Tian, Kun Ren, Hai-Peng Grebogi, Celso Batista, Antonio M. Graduate Program in Science - Physics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Department of Mathematics and Statistics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Department of Physics State University of Ponta Grossa Ponta GrossaPR84030-900 Brazil Center for Mathematics Computation and Cognition Federal University of ABC São Bernardo do CampoSP09606-045 Brazil Institute of Physics University of São Paulo São PauloSP05508-900 Brazil Faculty of Telêmaco Borba FATEB Telêmaco BorbaPR84266-010 Brazil Graduate Program in Chemical Engineering Federal Technological University of Paraná Ponta Grossa Paraná84016-210 Brazil Shaanxi Key Lab of Complex System Control and Intelligent Information Processing Xi’an University of Technology Xi’an710048 China Xi’an Technological University Xi’an710021 China Institute for Complex Systems and Mathematical Biology University of Aberdeen AberdeenAB24 3UE United Kingdom

Cancer is a term used to refer to a large set of diseases. The cancerous cells grow and divide and, as a result, they form tumours that grow in size. The immune system recognise the cancerous cells and attack them, though, it can be weakened by the cancer. One type of cancer treatment is chemotherapy, which uses drugs to kill cancer cells. Clinical, experimental, and theoretical research has been developed to understand the dynamics of cancerous cells with chemotherapy treatment, as well as the interaction between tumour growth and immune system. We study a mathematical model that describes the cancer growth, immune system response, and chemotherapeutic agents. The immune system is composed of resting cells that are converted to hunting cells to combat the cancer. In this work, we consider drug sensitive and resistant cancer cells. We show that the tumour growth can be controlled not only by means of different chemotherapy protocols, but also by the immune system that attacks both sensitive and resistant cancer cells. Furthermore, for all considered protocols, we demonstrate that the time delay from resting to hunting cells plays a crucial role in the combat against cancer cells. Copyright © 2020, The Authors. All rights reserved.

关键词： Chemotherapy

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Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019

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eClinicalMedicine 2023年 64卷 102193-102193页

作者： Wu, Dongze Jin, Yingzhao Xing, Yuhan Abate, Melsew Dagne Abbasian, Mohammadreza Abbasi-Kangevari, Mohsen Abbasi-Kangevari, Zeinab Abd-Allah, Foad Abdelmasseh, Michael Abdollahifar, Mohammad-Amin Abdulah, Deldar Morad Abedi, Aidin Abedi, Vida Abidi, Hassan Aboagye, Richard Gyan Abolhassani, Hassan Abuabara, Katrina Abyadeh, Morteza Addo, Isaac Yeboah Adeniji, Kayode Nelson Adepoju, Abiola Victor Adesina, Miracle Ayomikun Adnani, Qorinah Estiningtyas Sakilah Afarideh, Mohsen Aghamiri, Shahin Agodi, Antonella Agrawal, Anurag Arriagada, Constanza Elizabeth Aguilera Ahmad, Aqeel Ahmad, Danish Ahmad, Sohail Ahmadi, Ali Ahmed, Ayman Aithala, Janardhana P. Ajadi, Abdullateef Abiodun Ajami, Marjan Akbarzadeh-Khiavi, Mostafa Alahdab, Fares AlBataineh, Mohammad T. Alemi, Sharifullah Al-Gheethi, Adel Ali Saeed Ali, Liaqat Alif, Sheikh Mohammad Almazan, Joseph Uy Almustanyir, Sami Alqahtani, Jaber S. Alqasmi, Ibrahim Altaf, Ihsan Ullah Khan Alvis-Guzman, Nelson Alvis-Zakzuk, Nelson J. Al-Worafi, Yaser Mohammed Aly, Hany Amani, Reza Amu, Hubert Amusa, Ganiyu Adeniyi Andrei, Catalina Liliana Ansar, Adnan Ansariniya, Hossein Anyasodor, Anayochukwu Edward Arabloo, Jalal Arefnezhad, Reza Arulappan, Judie Asghari-Jafarabadi, Mohammad Ashraf, Tahira Atata, Jamila Abdulhamid Athari, Seyyed Shamsadin Atlaw, Daniel Atout, Maha Moh'd Wahbi Aujayeb, Avinash Awan, Asma Tahir Ayatollahi, Haleh Azadnajafabad, Sina Azzam, Ahmed Y. Badawi, Alaa Badiye, Ashish D. Bagherieh, Sara Baig, Atif Amin Bantie, Berihun Bantie Barchitta, Martina Bardhan, Mainak Barker-Collo, Suzanne Lyn Barone-Adesi, Francesco Batra, Kavita Bayileyegn, Nebiyou Simegnew Behnoush, Amir Hossein Belgaumi, Uzma Iqbal Bemanalizadeh, Maryam Bensenor, Isabela M. Beyene, Kebede A. Bhagavathula, Akshaya Srikanth Bhardwaj, Pankaj Bhaskar, Sonu Bhat, Ajay Nagesh Bitaraf, Saeid Bitra, Veera R. Boloor, Archith Bora, Kaustubh Botelho, João Silva Buchbinder, Rachelle Calina, Daniela Cámera, Luis Alberto Carvalho, Andre F. Chan, Jeffrey Shi Kai Chattu, Vijay Kumar Abebe, Endeshaw Chekol Department of Rheumatology and Immunology Sichuan Provincial People's Hospital School of Medicine University of Electronic Science and Technology of China China Department of Medicine & Therapeutics The Chinese University of Hong Kong Hong Kong Department of Paediatrics The Chinese University of Hong Kong Hong Kong School of Pharmacy The Chinese University of Hong Kong Hong Kong Jockey Club School of Public Health and Primary Care The Chinese University of Hong Kong Hong Kong Department of Nursing Woldia University Woldia Ethiopia Department of Orthopedic Surgery Harvard University Boston MA United States Postgraduate Medical Education Harvard University Boston MA United States Maternal Fetal Care Center Harvard University Boston MA United States Department of Health Policy and Oral Epidemiology Harvard University Boston MA United States Division of General Internal Medicine Harvard University Boston MA United States Department of Orthopaedic Surgery Shahid Beheshti University of Medical Sciences Tehran Iran Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Department of Biotechnology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Epidemiology Shahid Beheshti University of Medical Sciences Tehran Iran National Nutrition and Food Technology Research Institute Shahid Beheshti University of Medical Sciences Tehran Iran Department of Immunology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Neurology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Medical Genetics Shahid Beheshti University of Medical Sciences Tehran Iran Center for Comprehensive Genetic Services Shahid Beheshti University of Medical Sciences Tehran Iran Cancer Research Center Shahid Beheshti University of Medical Sciences Tehran Iran Department of Health Economics and Statistics Shahid Beheshti University of Medical Sciences Tehran Iran Functional Neuro

Background: The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods: We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings: In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of −0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = −0.41), inflammatory bowel disease (AAPC = −0.72), multiple sclerosis (AAPC = −0.26), psoriasis (AAPC = −0.77), and atopic dermatitis (AAPC = −0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR. Interpretation: The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rh

关键词： Global burden of disease study Immune-mediated inflammatory disease Incidence Trend

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Correction to: chemical composition of essential oils of eight Tunisian Eucalyptus species and their antibacterial activity against strains responsible for otitis

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BMC complementary medicine and therapies 2021年第1期21卷 241页

作者： Elaissi Ameur Moumni Sarra Derbali Yosra Khouja Mariem Abid Nabil Frederic Lynen Khouja Mohamed Larbi Chemical Pharmacological and Gallenic Development Laboratory University of Monastir Faculty of Pharmacy Avenue Avicennne 5000 Monastir Tunisia. aelaissi@yahoo.fr. Chemical Pharmacological and Gallenic Development Laboratory University of Monastir Faculty of Pharmacy Avenue Avicennne 5000 Monastir Tunisia. University of Carthage The National Research Institute of Rural Engineering Water and Forestry INRGREF Laboratory of Management and Valorization of Forest Resources BP 10 2080 Ariana Tunisia. Laboratory of Transmissible Diseases and Biological Active Substances LR99ES27 Faculty of Pharmacy University of Monastir Monastir Tunisia. High Institute of Biotechnology of Sidi Thabet University of Manouba Manouba Tunisia. Separation Science Group Department of Organic and Macromolecular Chemistry Faculty of Sciences Ghent University Krijgslaan 281-S4 Bis B-9000 Ghent Belgium.

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Manifold learning for organizing unstructured sets of process observations

arXiv

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arXiv 2018年

作者： Dietrich, Felix Kooshkbaghi, Mahdi Bollt, Erik M. Kevrekidis, Ioannis G. Department of Chemical and Biomolecular Engineering Department of Applied Mathematics and Statistics Johns Hopkins University BaltimoreMD21218 United States Program in Applied and Computational Mathematics Princeton University PrincetonNJ08544 United States Department of Mathematics Department of Electrical and Computer Engineering Clarkson Center for Complex Systems Science Clarkson University PotsdamNY13699-5815 United States

Data mining is routinely used to organize ensembles of short temporal observations so as to reconstruct useful, low-dimensional realizations of an underlying dynamical system. In this paper, we use manifold learning to organize unstructured ensembles of observations ("trials") of a system's response surface. We have no control over where every trial starts;and during each trial operating conditions are varied by turning "agnostic" knobs, which change system parameters in a systematic but unknown way. As one (or more) knobs "turn" we record (possibly partial) observations of the system response. We demonstrate how such partial and disorganized observation ensembles can be integrated into coherent response surfaces whose dimension and parametrization can be systematically recovered in a data-driven fashion. The approach can be justified through the Whitney and Takens embedding theorems, allowing reconstruction of manifolds/attractors through different types of observations. We demonstrate our approach by organizing unstructured observations of response surfaces, including the reconstruction of a cusp bifurcation surface for Hydrogen combustion in a Continuous Stirred Tank Reactor. Finally, we demonstrate how this observation-based reconstruction naturally leads to informative transport maps between input parameter space and output/state variable *** codes 37M20 Copyright © 2018, The Authors. All rights reserved.

关键词： Dynamical systems

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