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Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers Abstracts

FLUIDS AND BARRIERS OF THE CNS 2017年第SUPPL 2期14卷 27-27页

作者： [Anonymous] The Jerzy Kukuczka Academy of Physical Education Katowice Poland The Institute of Animal Physiology and Food Research Polish Academy of Sciences Olsztyn Poland University of Miami Miami FL USA Institute of Pharmaceutical Science King’s College London London United Kingdom Department of Ophthalmology and Molecular and Integrative Physiology The University of Michigan Ann Arbor MI USA Department of Internal Medicine and Cardiology The University of Michigan Ann Arbor MI USA School of Medicine Department of Cellular and Molecular Medicine Koc University Istanbul Turkey Department of Cellular and Molecular Medicine Medical Faculty Koc University Istanbul Turkey Department of Neuroscience School of Medicine Koc University Istanbul Turkey Department of Neuroscience Medical Faculty Koc University Istanbul Turkey Department of Laboratory Animals Science Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey Department of Neuroscience Aziz Sancar Experimental Medicine Research Institute Istanbul University Istanbul Turkey School of Medicine Koc University Istanbul Turkey Department of Forensic Science Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Histology and Embryology School of Medicine Koc University Istanbul Turkey Department of Histology and Embryology Istanbul Faculty of Medicine Istanbul University Istanbul Turkey Department of Physiology School of Medicine Koc University Istanbul Turkey Theodor Kocher Institute University of Bern Bern Switzerland Institute of Veterinary Physiology Vetsuisse Faculty University of Zurich Zurich Switzerland Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Zurich Center of Integrative Human Physiology University of Zurich Zurich Switzerland Institute for Veterinary Physiology and Zurich Center for Integrative Human Physiology University of Zurich Zurich Switzerland Institute of Veterinary Physiology Univer

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25th Annual Computational Neuroscience Meeting CNS-2016, Seogwipo City, South Korea, July 2-7, 2016 Abstracts

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BMC NEUROscience 2016年第1期17卷 1-112页

作者： [Anonymous] Computational Neurobiology Laboratory The Salk Institute for Biological Studies San Diego USA UNIC CNRS Gif sur Yvette France The European Institute for Theoretical Neuroscience (EITN) Paris France ATR Computational Neuroscience Laboratories Kyoto Japan Krembil Research Institute University Health Network Toronto Canada Department of Physiology University of Toronto Toronto Canada Department of Medicine (Neurology) University of Toronto Toronto Canada Department of Physics University of New Hampshire Durham USA Department of Neurophysiology Nencki Institute of Experimental Biology Warsaw Poland Department of Theory Wigner Research Centre for Physics of the Hungarian Academy of Sciences Budapest Hungary Department of Mathematical Sciences KAIST Daejoen Republic of Korea Department of Mathematics University of Houston Houston USA Department of Biochemistry & Cell Biology and Institute of Biosciences and Bioengineering Rice University Houston USA Department of Biology and Biochemistry University of Houston Houston USA Grupo de Neurocomputación Biológica Dpto. de Ingeniería Informática Escuela Politécnica Superior Universidad Autónoma de Madrid Madrid Spain Department of Biological Sciences University of Southern California Los Angeles USA Center for Neuroscience Korea Institute of Science and Technology Seoul South Korea Department of Neurology Albert Einstein College of Medicine Bronx USA Center for Neuroscience KIST Seoul South Korea Department of Neuroscience University of Science and Technology Daejon South Korea Systems Neuroscience Group QIMR Berghofer Medical Research Institute Herston Australia Department of Psychology Yonsei University Seoul South Korea Department of Psychiatry Kyung Hee University Hospital at Gangdong Seoul South Korea Department of Psychiatry Veterans Administration Boston Healthcare System and Harvard Medical School Brockton USA Department of Electrical and Electronic Engineering The University of Melbourne Parkvil

A1 Functional advantages of cell-type heterogeneity in neural circuits Tatyana O. Sharpee A2 Mesoscopic modeling of propagating waves in visual cortex Alain Destexhe A3 Dynamics and biomarkers of mental disorders Mitsuo Kawato F1 Precise recruitment of spiking output at theta frequencies requires dendritic h-channels in multi-compartment models of oriens-lacunosum/moleculare hippocampal interneurons Vladislav Sekulić, Frances K. Skinner F2 Kernel methods in reconstruction of current sources from extracellular potentials for single cells and the whole brains Daniel K. Wójcik, Chaitanya Chintaluri, Dorottya Cserpán, Zoltán Somogyvári F3 The synchronized periods depend on intracellular transcriptional repression mechanisms in circadian clocks. Jae Kyoung Kim, Zachary P. Kilpatrick, Matthew R. Bennett, Kresimir Josić O1 Assessing irregularity and coordination of spiking-bursting rhythms in central pattern generators Irene Elices, David Arroyo, Rafael Levi, Francisco B. Rodriguez, Pablo Varona O2 Regulation of top-down processing by cortically-projecting parvalbumin positive neurons in basal forebrain Eunjin Hwang, Bowon Kim, Hio-Been Han, Tae Kim, James T. McKenna, Ritchie E. Brown, Robert W. McCarley, Jee Hyun Choi O3 Modeling auditory stream segregation, build-up and bistability James Rankin, Pamela Osborn Popp, John Rinzel O4 Strong competition between tonotopic neural ensembles explains pitch-related dynamics of auditory cortex evoked fields Alejandro Tabas, André Rupp, Emili Balaguer-Ballester O5 A simple model of retinal response to multi-electrode stimulation Matias I. Maturana, David B. Grayden, Shaun L. Cloherty, Tatiana Kameneva, Michael R. Ibbotson, Hamish Meffin O6 Noise correlations in V4 area correlate with behavioral performance in visual discrimination task Veronika Koren, Timm Lochmann, Valentin Dragoi, Klaus Obermayer O7 Input-location dependent gain modulation in cerebellar nucleus neurons Maria Psarrou, Maria Schilstra, Neil Davey, Benjamin Torben-Ni

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Measuring Nanoscale Thermostability of Cell Membranes with Single Gold–Diamond Nanohybrids

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Angewandte Chemie 2017年第11期129卷

作者： Pei‐Chang Tsai Chandra P. Epperla Jo‐Shan Huang Oliver Y. Chen Chih‐Che Wu Huan‐Cheng Chang Institute of Atomic and Molecular Sciences Academia Sinica Taipei 106 Taiwan Taiwan International Graduate Program Academia Sinica Taipei 115 Taiwan Department of Chemistry National Tsing Hua University Hsinchu 300 Taiwan Department of Applied Chemistry National Chi Nan University Puli Nantou 545 Taiwan Department of Chemical Engineering National Taiwan University of Science and Technology Taipei 106 Taiwan

Much of the current understanding of thermal effects in biological systems is based on macroscopic measurements. There is little knowledge about the local thermostability or heat tolerance of subcellular components at the nanoscale. Herein, we show that gold nanorod–fluorescent nanodiamond (GNR‐FND) hybrids are useful as a combined nanoheater/nanothermometer in living cells. With the use of a 594 nm laser for both heating and probing, we measure the temperature changes by recording the spectral shifts of the zero‐phonon lines of negatively charged nitrogen‐vacancy centers in FNDs. The technique allows us to determine the rupture temperatures of individual membrane nanotubes in human embryonic kidney cells, as well as to generate high temperature gradients on the cell membrane for photoporation and optically controlled hyperthermia. Our results demonstrate a new paradigm for hyperthermia research and application.

关键词： Farbzentren Gold-Nanostäbchen Membran-Nanoröhren Nanodiamanten Thermometrie

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Intrinsic Raman signatures of pristine hybrid perovskite CH3NH3PbI3 and its multiple stages of structure transformation

Intrinsic Raman signatures of pristine hybrid perovskite CH3...

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2016 IEEE 43rd Photovoltaic Specialists Conference (PVSC)

作者： Qiong Chen Henan Liu Hui-Seon Kim Yucheng Liu Mengjin Yang Naili Yue Gang Ren Kai Zhu Shengzhong Frank Liu Nam-Gyu Park Yong Zhang Department of Electrical and Computer Engineering The University of North Carolina at Charlotte Charlotte NC USA Optical Science and Engineering graduate program The University of North Carolina at Charlotte Charlotte NC USA Department of Energy Science Sungkyunkwan University Suwon South Korea National Ministry of Education Shaanxi Normal University Xi'an China Chemical and Materials Science Center National Renewable Energy Laboratory CO USA Molecular Foundry Lawrence Berkeley National Laboratory Berkeley CA USA Key Laboratory of Applied Surface and Colloid Chemistry National Ministry of Education Shaanxi Normal University Xi'an Shaanxi CN School of Chemical Engineering Sungkyunkwan University Suwon South Korea University of North Carolina at Charlotte Charlotte NC US

By performing spatially resolved Raman and photoluminescence spectroscopy with different illumination conditions, we have achieved a unified understanding towards the spectroscopy signatures of the organic-inorganic hybrid perovskite, transforming from the pristine state (CH 3 NH 3 PbI 3 or MAPbI 3 ) to fully degraded state (i.e., PbI 2 ), for samples with varying crystalline domain size from mesoscopic scale to macroscopic size, synthesized by three different techniques.

关键词： Measurement by laser beam Density measurement Chemistry Lighting Optical films Degradation Spectroscopy

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Unconventional Carbon: Alkaline Dehalogenation of Polymers Yields N‐Doped Carbon Electrode for High‐Performance Capacitive Energy Storage

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Advanced Functional Materials 2016年第19期26卷

作者： Guoxin Zhang Lin Wang Yongchao Hao Xiuyan Jin Yuqi Xu Yun Kuang Liming Dai Xiaoming Sun State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Beijing 100029 China Department of Macromolecular Science and Engineering Case School of Engineering Case Western Reserve University 10900 Euclid Avenue Cleveland OH 44106 USA

Polymers are important precursors for the fabrication of carbon materials. Herein, halogenated polymers are explored as precursors for the synthesis of high‐quality carbon materials via alkaline dehalogenation. It is found that the halogen elements (F, Cl) connecting to vinylidene units are highly reactive so that dehalogenation can take place a few seconds at room temperature by simple hand grinding in the presence of strong inorganic alkaline. Furthermore, the halogen element‐leaving sites are shown to be susceptible to heteroatom doping (e.g., N doping) to become stable capacitive sites for charge storage (e.g., ions). By using a mixture of NaOEt and KOH as dehalogenation reagents, abundant hierarchical pores (macro/meso/micropores) in the resultant doped carbon matrix for fast mass transportation can be created. Very high capacitance (328 F g −1 at 0.5 A g −1 ) and rate capability (75.3% retention at 50 A g −1 and 62.5% retention at 100 A g −1 ) are observed for the newly developed halogenated polymer‐derived doped carbon materials.

关键词： carbon nanomaterials C–C coupling halogenated polymers supercapacitor

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The AFLOW fleet for materials discovery

arXiv

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arXiv 2017年

作者： Toher, Cormac Oses, Corey Hicks, David Gossett, Eric Rose, Frisco Nath, Pinku Usanmaz, Demet Ford, Denise C. Perim, Eric Calderon, Camilo E. Plata, Jose J. Lederer, Yoav Jahnátek, Michal Setyawan, Wahyu Wang, Shidong Xue, Junkai Rasch, Kevin Chepulskii, Roman V. Taylor, Richard H. Gomez, Geena Shi, Harvey Supka, Andrew R. Al Orabi, Rabih Al Rahal Gopal, Priya Cerasoli, Frank T. Liyanage, Laalitha Wang, Haihang Siloi, Ilaria Agapito, Luis A. Nyshadham, Chandramouli Hart, Gus L.W. Carrete, Jesús Legrain, Fleur Mingo, Natalio Zurek, Eva Isayev, Olexandr Tropsha, Alexander Sanvito, Stefano Hanson, Robert M. Takeuchi, Ichiro Mehl, Michael J. Kolmogorov, Aleksey N. Yang, Kesong D'Amico, Pino Calzolari, Arrigo Costa, Marcio De Gennaro, Riccardo Nardelli, Marco Buongiorno Fornari, Marco Levy, Ohad Curtarolo, Stefano Department of Mechanical Engineering and Materials Science Duke University DurhamNC27708 United States Center for Materials Genomics Duke University DurhamNC27708 United States Departamento de Química Física Universidad de Sevilla Sevilla41012 Spain Department of Physics NRCN P.O. Box 9001 Beer-Sheva84190 Israel Department of Materials Science and Engineering Massachusetts Institute of Technology MA02139 United States Department of Physics and Science of Advanced Materials Program Central Michigan University Mount PleasantMI48859 United States Science of Advanced Materials Program Central Michigan University Mount PleasantMI United States Solvay Design and Development of Functional Materials Department AXEL'ONE Collaborative Platform - Innovative Materials Saint Fons Cedex69192 France Department of Physics Department of Chemistry University of North Texas DentonTX76203 United States Department of Physics and Astronomy Brigham Young University ProvoUT84602 United States Institute of Materials Chemistry TU Wien ViennaA-1060 Austria Universite e Grenoble Alpes Grenoble38000 France CEA LITEN 17 Rue des Martyrs Grenoble38054 France Department of Chemistry State University of New York at Buffalo BuffaloNY14260 United States Laboratory for Molecular Modeling Division of Chemical Biology and Medicinal Chemistry UNC Eshelman School of Pharmacy University of North Carolina Chapel HillNC27599 United States School of Physics AMBER and CRANN Institute Trinity College Dublin 2 Ireland Department of Chemistry St. Olaf College NorthfieldMN55057 United States Center for Nanophysics and Advanced Materials University of Maryland College ParkMD20742 United States Department of Materials Science and Engineering University of Maryland College ParkMD20742 United States United States Naval Academy AnnapolisMD21402 United States Department of Physics Binghamton University State University of New York BinghamtonNY13902 United States Depart

The traditional paradigm for materials discovery has been recently expanded to incorporate substantial data driven research. With the intent to accelerate the development and the deployment of new technologies, the AFLOW Fleet for computational materials design automates high-throughput first principles calculations, and provides tools for data verification and dissemination for a broad community of users. AFLOW incorporates different computational modules to robustly determine thermodynamic stability, electronic band structures, vibrational dispersions, thermo-mechanical properties and more. The AFLOW data repository is publicly accessible online at ***, with more than 1.7 million materials entries and a panoply of queryable computed properties. Tools to programmatically search and process the data, as well as to perform online machine learning predictions, are also available. Copyright © 2017, The Authors. All rights reserved.

关键词： Calculations

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Facile fabrication of 3D layer-by-layer graphene-gold nanorod hybrid architecture for hydrogen peroxide based electrochemical biosensor

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Sensing and Bio-Sensing Research 2015年 3卷 7-11页

作者： Xue, Chenming Kung, Chih-Chien Gao, Min Liu, Chung-Chiun Dai, Liming Urbas, Augustine Li, Quan Kent State University Kent 44242 OH United States Department of Chemical Engineering Case Western Reserve University Cleveland 44106 OH United States Department of Macromolecular Science and Engineering Case Western Reserve University Cleveland 44106 OH United States Materials and Manufacturing Directorate Air Force Research Laboratory WPAFB 45433 OH United States

Three-dimensional (3D) layer-by-layer graphene-gold nanorod (GNR) architecture has been constructed. The resulting hybrid nanomaterials' architecture has been tested for detecting hydrogen peroxide (H₂O₂) through the electrocatalytic reaction on a three electrode disposable biosensor platform. Cyclic voltammetry and amperometry were used to characterize and assess the performance of the biosensor. The 3D layer-by-layer modified electrode exhibited the highest sensitivity compared to the active carbon, graphene-oxide, cysteine-graphene oxide and GNR coated electrodes. This research explored the feasibility of using the 3D hybrid graphene-GNR as a template for biosensor. The 3D hybrid structure exhibited higher sensitivity than GNRs alone. SEM showed the explanation that GNRs had self-aggregates reducing the contact surface area when coated on the active carbon electrode, while there were no such aggregates in the 3D structure, and TEM illustrated that GNRs dispersed well in the 3D structure. This research demonstrated a better way to prepare well-separated metal nanoparticles by using the 3D layer-by-layer structure. Consequently, other single and bi-metallic metal nanoparticles could be incorporated into such structure. As a practical example, 3D layer-by-layer nanomaterials modified active carbon electrode was used for detecting glucose showing very good sensitivity and minimum interference by ascorbic acid and uric acid in test solution, which indicated a good selectivity of the biosensor as well. © 2014 The Authors.

关键词： 3D hybrid nanostructure Biosensor Gold nanorod Graphene H2O2 detection

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Magnetoelectric memory function with optical readout

arXiv

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arXiv 2017年

作者： Kocsis, V. Penc, K. Rõõm, T. Nagel, U. Vít, J. Romhányi, J. Tokunaga, Y. Taguchi, Y. Tokura, Y. Kézsmárki, I. Bordács, S. Wako Saitama351-0198 Japan Department of Physics Budapest University of Technology and Economics and MTA-BME Lendület Magneto-optical Spectroscopy Research Group Budapest1111 Hungary Institute for Solid State Physics and Optics Wigner Research Centre for Physics Hungarian Academy of Sciences P.O.B. 49 BudapestH-1525 Hungary National Institute of Chemical Physics and Biophysics Tallinn12618 Estonia Institute of Physics ASCR Na Slovance 2 Prague 8182 21 Eue Faculty of Nuclear Science and Physical Engineering Czech Technical University Břehová 7 Prague 1115 19 Eue Okinawa Institute of Science and Technology Graduate University Onna-sonOkinawa904-0395 Japan Department of Advanced Materials Science University of Tokyo Kashiwa277-8561 Japan Quantum-Phase Electronics Center Department of Applied Physics University of Tokyo Tokyo113-8656 Japan Department of Applied Physics University of Tokyo Hongo Tokyo113-8656 Japan Experimental Physics 5 Center for Electronic Correlations and Magnetism Institute of Physics University of Augsburg Augsburg86159 Germany Hungarian Academy of Sciences Premium Postdoctor Program Budapest1051 Hungary

The ultimate goal of multiferroic research is the development of new-generation non-volatile memory devices1, the so-called magnetoelectric (ME) memories, where magnetic bits are controlled via electric fields without the application of electrical currents subject to dissipation. This low-power operation exploits the entanglement of the magnetization and the electric polarization coexisting in multiferroic materials2,3. Here we demonstrate the optical readout of ME memory states in the antiferromagnetic (AFM) and antiferroelectric (AFE) LiCoPO4, based on the strong absorption difference of THz radiation between its two types of ME domains. This unusual contrast is attributed to the dynamic ME effect of the spin-wave excitations, as confirmed by our microscopic model, which also captures the characteristics of the observed static ME effect. Our proof-of-principle study, demonstrating the control and the optical readout of ME domains in LiCoPO4, lays down the foundation for future ME memory devices based on antiferroelectric-antiferromagnetic insulators. Copyright © 2017, The Authors. All rights reserved.

关键词： Digital storage

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Recent innovations in material research

Recent innovations in material research

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作者： Cai, W.J. Chen, D. Hu, H. Huang, X.P. Khotsyanovskii, A.O. Li, X.S. Silva, F.J.G. Yao, S.H. Zheng, H.N. Department of Chemical Materials and Biomolecular Engineering University of Connecticut United States School of Engineering and Applied Science Harvard University United States Department of Mechanical Automotive and Materials Engineering University of Windsor Canada Department of Mechanical Engineering Massachusetts Institute of Technology United States Pisarenko Institute of Problems of Strength National Academy of Sciences of Ukraine Ukraine Mechanical Engineering Department ISEP School of Engineering Polytechnic of Porto Portugal Bachelor Degree Program in Technology Management Chang Jung Christian University Taiwan

The new trends and developments in the novel functional materials and material research innovations presented at the 3rd Global Conference on Materials science and engineering (CMSE2014), which was held on 20-23 October 2014 in Shanghai, China, is discussed. R. Toyoda, M. Tawata, M. Hashimoto, and Y. Matsumura presented 'Internal stress control of transition-metal thin films', where the effects of ion bombardment parameter Pi on the internal stress of thin films were evaluated. X.G. Wang, Z.L. Chen, and X.Y. Wang presented their study 'Measurement of the interface characteristic based on ultrasonic longitudinal wave', which provided a lucrative alternative to conventional ultrasonic techniques, since it allows one to avoid the mutual superposition of reflected waves at the same thin coating interface. P. Wang and C.Y. Zhao presented their 'Study on reducing railway noise by porous concrete sound-absorbing panel', which is crucial for noise reduction near the railway lines. In the paper entitled 'Numerical study on the heat preservation of the ladle used for twin-roll strip casting', J.H. Dong, M. Chen and N. Wang developed a 3D mathematical model, in order to analyze the heat transfer and temperature drop on the ladle using the finite volume method.

关键词： Finite volume method

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Electrocatalysts: In Situ Electrochemical Activation of Atomic Layer Deposition Coated MoS2Basal Planes for Efficient Hydrogen Evolution Reaction (Adv. Funct. Mater. 34/2017)

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Advanced Functional Materials 2017年第34期27卷

作者： Youngmin Kim David H. K. Jackson Daewon Lee Min Choi Tae‐Wan Kim Soon‐Yong Jeong Ho‐Jeong Chae Hyun Woo Kim Noejung Park Hyunju Chang Thomas F. Kuech Hyung Ju Kim Carbon Resources Institute Korea Research Institute of Chemical Technology 141 Gajeong‐ro Yuseong‐gu Daejeon 34114 South Korea Materials Science Program University of Wisconsin‐Madison 1509 University Ave. Madison WI 53706 USA Center for Molecular Modeling and Simulation Korea Research Institute of Chemical Technology 141 Gajeong‐ro Yuseong‐gu Daejeon 34114 South Korea Department of Chemistry Ulsan National Institute of Science and Technology 50 UNIST‐gil Banyeon‐ri Eonyang‐eup Ulju‐gun Ulsan 44919 South Korea Department of Physics Ulsan National Institute of Science and Technology 50 UNIST‐gil Banyeon‐ri Eonyang‐eup Ulju‐gun Ulsan 44919 South Korea Department of Chemical and Biological Engineering University of Wisconsin‐Madison 1415 Engineering Dr. Madison WI 53706 USA Department of Green Chemistry and Biotechnology University of Science and Technology 113 Gwahangno Yuseong Daejeon 34113 South Korea

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