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A swin transformer and CNN fusion framework for accurate Parkinson disease classification in MRI

Scientific Reports 2025年第1期15卷 1-14页

作者： Hussain, Sayyed Shahid Shah, Pir Masoom Dawood, Hussain Degang, Xu Alshamayleh, Ahmad Khan, Muhammad Adnan Ghazal, Taher M. School of Automation Central South University Changsha 410083 China School of Computer Science and Engineering Central South University Changsha 410010 China Department of Computer Science Bacha Khan University Charsadda Pakistan School of Computing Skyline University College Sharjah United Arab Emirates Department of Data Science and Artificial Intelligence Hourani Center for Applied Scientific Research Al-Ahliyya Amman University Amman Jordan Department of Software Faculty of Artificial Intelligence and Software Gachon University Seongnam-si 13120 South Korea Riphah School of Computing and Innovation Riphah International University Lahore Campus Lahore 54000 Pakistan Chitkara University Institute of Engineering and Technology Chitkara University Punjab Rajpura 140401 India Networks and Cybersecurity Department Hourani Center for Applied Scientific Research Al-Ahliyya Amman University Amman Jordan

Parkinson’s disease ranks as the second most prevalent neurological disorder after Alzheimer’s disease. Convolutional neural networks (CNNs) have been extensively employed in Parkinson’s disease (PD) detection using MR images. However, CNN models generally focus on local features while prone to capture global representations. On the other hand, the vision transformer (ViT) excels at capturing global features through its self-attention mechanism, but it compromises local feature representations. Additionally, the varying magnitude of MR data poses a challenge for ViT, potentially leading to the gradient vanishing problem. To address these limitations, this paper proposed a novel framework that combines the Swin-Transformer and CNN to capture both local and global features effectively. To mitigate the gradient vanishing issue in ViT, we used skipped connections and cosine attention mechanism in VIT that preserves the output distribution regardless of input magnitude variations. The proposed model comprises three primary blocks: Transformer-block, convolutional block, and dense-block. The input image is processed concurrently by the cosine transformer and convolutional block. Subsequently, the extracted features from both blocks are concatenated and fed to the dense block for decision-making. The proposed model achieved promesing results of 96%, 97%, 95%, and 95% in terms of accuracy, sensitivity, specificity, and area under the curve, respectively. © The Author(s) 2025.

关键词： CNN Cosine similarity MRI Parkinson’s disease Swin-transformer

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Artificial intelligence for modelling infectious disease epidemics

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Nature 2025年第8051期638卷 623-635页

作者： Kraemer, Moritz U. G. Tsui, Joseph L.-H. Chang, Serina Y. Lytras, Spyros Khurana, Mark P. Vanderslott, Samantha Bajaj, Sumali Scheidwasser, Neil Curran-Sebastian, Jacob Liam Semenova, Elizaveta Zhang, Mengyan Unwin, H. Juliette T. Watson, Oliver J. Mills, Cathal Dasgupta, Abhishek Ferretti, Luca Scarpino, Samuel V. Koua, Etien Morgan, Oliver Tegally, Houriiyah Paquet, Ulrich Moutsianas, Loukas Fraser, Christophe Ferguson, Neil M. Topol, Eric J. Duchêne, David A. Stadler, Tanja Kingori, Patricia Parker, Michael J. Dominici, Francesca Shadbolt, Nigel Suchard, Marc A. Ratmann, Oliver Flaxman, Seth Holmes, Edward C. Gomez-Rodriguez, Manuel Schölkopf, Bernhard Donnelly, Christl A. Pybus, Oliver G. Cauchemez, Simon Bhatt, Samir Pandemic Sciences Institute University of Oxford Oxford United Kingdom Department of Biology University of Oxford Oxford United Kingdom Department of Electrical Engineering and Computer Science University of California Berkeley Berkeley CA United States UCSF UC Berkeley Joint Program in Computational Precision Health Berkeley CA United States Division of Systems Virology Department of Microbiology and Immunology The Institute of Medical Science The University of Tokyo Tokyo Japan Section of Epidemiology Department of Public Health University of Copenhagen Copenhagen Denmark Oxford Vaccine Group University of Oxford and NIHR Oxford Biomedical Research Centre Oxford United Kingdom Department of Epidemiology and Biostatistics Imperial College London London United Kingdom Department of Computer Science University of Oxford Oxford United Kingdom School of Mathematics University of Bristol Bristol United Kingdom MRC Centre for Global Infectious Disease Analysis School of Public Health Imperial College London London United Kingdom Department of Statistics University of Oxford Oxford United Kingdom Doctoral Training Centre University of Oxford Oxford United Kingdom Institute for Experiential AI Northeastern University MA Boston Thailand Santa Fe Institute Santa Fe NM United States World Health Organization Regional Office for Africa Brazzaville Congo WHO Hub for Pandemic and Epidemic Intelligence Health Emergencies Programme World Health Organization Berlin Germany Centre for Epidemic Response and Innovation (CERI) School for Data Science and Computational Thinking Stellenbosch University Stellenbosch South Africa African Institute for Mathematical Sciences (AIMS) South Africa Muizenberg Cape Town South Africa Genomics England London United Kingdom Scripps Research La Jolla CA United States Department of Biosystems Science and Engineering ETH Zürich Basel Switzerland Swiss Institute of Bioinformatics Lausanne Switzerland The Ethox Centre Nuffield

Infectious disease threats to individual and public health are numerous, varied and frequently unexpected. Artificial intelligence (ai) and related technologies, which are already supporting human decision making in economics, medicine and social science, have the potential to transform the scope and power of infectious disease epidemiology. Here we consider the application to infectious disease modelling of ai systems that combine machine learning, computational statistics, information retrieval and data science. We first outline how recent advances in ai can accelerate breakthroughs in answering key epidemiological questions and we discuss specific ai methods that can be applied to routinely collected infectious disease surveillance data. Second, we elaborate on the social context of ai for infectious disease epidemiology, including issues such as explainability, safety, accountability and ethics. Finally, we summarize some limitations of ai applications in this field and provide recommendations for how infectious disease epidemiology can harness most effectively current and future developments in ai. © Springer Nature Limited 2025.

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Tacchi 2.0: A Low Computational Cost and Comprehensive Dynamic Contact Simulator for Vision-based Tactile Sensors

arXiv

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arXiv 2025年

作者： Sun, Yuhao Zhang, Shixin Li, Wenzhuang Zhao, Jie Shan, Jianhua Shen, Zirong Chen, Zixi Sun, Fuchun Guo, Di Fang, Bin School of Artificial Intelligence Beijing University of Posts and Telecommunications Beijing100083 China Beijing100083 China School of International Beijing University of Posts and Telecommunications Beijing100876 China School of Mechanical Engineering Anhui University of Technology China Zhili College Tsinghua University Beijing100084 China Biorobotics Institute The Department of Excellence in Robotics and AI Scuola Superiore Sant’Anna Pisa56127 Italy Institute for Artificial Intelligence Department of Computer Science and Technology Beijing National Research Center for Information Science and Technology Tsinghua University Beijing100084 China

With the development of robotics technology, some tactile sensors, such as vision-based sensors, have been applied to contact-rich robotics tasks. However, the durability of vision-based tactile sensors significantly increases the cost of tactile information acquisition. Utilizing simulation to generate tactile data has emerged as a reliable approach to address this issue. While data-driven methods for tactile data generation lack robustness, finite element methods (FEM) based approaches require significant computational costs. To address these issues, we integrated a pinhole camera model into the low computational cost vision-based tactile simulator Tacchi that used the Material Point Method (MPM) as the simulated method, completing the simulation of marker motion images. We upgraded Tacchi and introduced Tacchi 2.0. This simulator can simulate tactile images, marked motion images, and joint images under different motion states like pressing, slipping, and rotating. Experimental results demonstrate the reliability of our method and its robustness across various vision-based tactile sensors. © 2025, CC BY.

关键词： Pinhole cameras

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Cash Flow Forecasting Based on Wavelet Transform and Neural Networks 8

Cash Flow Forecasting Based on Wavelet Transform and Neural ...

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8th International Conference on computer science and engineering, UBMK 2023

作者： Soylen, Zumra Mammadova, Farida Fasounaki, Mandana Ozmen, Ayse Irem Ince, Gokhan Istanbul Technical University Department of Computer Engineering İstanbul Turkey Mdp Group R&d Department İstanbul Turkey Istanbul Technical University Department of Computer Engineering & Ai and Data Science Application and Research Center İstanbul Turkey

ISBN: (纸本)9798350340815

Cash flow forecasting is a critical task for businesses and financial institutions to ensure effective financial planning and decision-making. However, limited data availability poses a significant challenge when developing accurate and robust cash flow prediction models. In this paper, we investigate the performance of various forecasting methods and propose an approach based on wavelet transform for improving the forecasting accuracy. We demonstrate the effectiveness of the proposed approach with the best combination of wavelet functions and methods for forecasting future values in a univariate time series. We investigate the impact of wavelet transform on forecasting techniques based on open-source datasets. Our methodology includes data collection, preprocessing, feature engineering, model selection, and experimentation using different performance evaluation metrics. © 2023 IEEE.

关键词： Forecasting

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Conditional Generative Modeling for Amorphous Multi-Element Materials

arXiv

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arXiv 2025年

作者： Li, Honglin Liu, Chuhao Guo, Yongfeng Luo, Xiaoshan Chen, Yijie Liu, Guangsheng Li, Yu Wang, Ruoyu Wang, Zhenyu Wu, Jianzhuo Ma, Cheng Xie, Zhuohang Lv, Jian Ding, Yufei Zhang, Huabin Luo, Jian Zhong, Zhicheng Li, Mufan Wang, Yanchao Li, Wan-Lu Key Laboratory of Material Simulation Methods and Software Ministry of Education College of Physics Jilin University Changchun China Aiiso Yufeng Li Family Department of Chemical and Nano Engineering University of California La Jolla San DiegoCA United States Institute of Molecular Engineering Plus College of Chemistry Fuzhou University Fuzhou China College of Chemistry and Molecular Engineering Peking University Beijing China School of Physics Nankai University Tianjin China Institute of Modern Physics Fudan University Shanghai China Program in Materials Science and Engineering University of California La Jolla San DiegoCA United States School of Artificial Intelligence and Data Science University of Science and Technology of China Hefei230026 China Suzhou Institute for Advanced Research University of Science and Technology of China Suzhou215123 China International Center of Future Science Jilin University Changchun China Department of Computer Science and Engineering University of California La Jolla San DiegoCA United States Center for Renewable Energy and Storage Technologies Physical Science and Engineering Division King Abdullah University of Science and Technology Thuwal Saudi Arabia Suzhou Lab Suzhou215123 China

Amorphous multi-element materials offer unprecedented tunability in composition and properties, yet their rational design remains challenging due to the lack of predictive structure-property relationships and the vast configurational space. Traditional modeling struggles to capture the intricate short-range order that dictates their stability and functionality. We here introduce ApolloX, a pioneering predictive framework for amorphous multi-element materials, establishing a new paradigm by integrating physics-informed generative modeling with particle swarm optimization, using chemical short-range order as an explicit constraint. By systematically navigating the disordered energy landscape, ApolloX enables the targeted design of thermodynamically stable amorphous configurations. It accurately predicts atomic-scale arrangements, including composition-driven metal clustering and amorphization trends, which are well-validated by experiments, while also guiding synthesis by leveraging sluggish diffusion to control elemental distribution and disorder. The resulting structural evolution, governed by composition, directly impacts catalytic performance, leading to improved activity and stability with increasing amorphization. This predictive-experimental synergy transforms the discovery of amorphous materials, unlocking new frontiers in catalysis, energy storage, and functional disordered systems. Copyright © 2025, The Authors. All rights reserved.

关键词： Amorphization

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A structural variation genotyping algorithm enhanced by CNV quantitative transfer

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Frontiers of computer science 2022年第6期16卷 159-165页

作者： Tian ZHENG Xinyang QIAN Jiayin WANG Department of Computer Science and Technology School of Electronic and Information EngineeringXi’an Jiaotong UniversityXi’an710049China Institute of Data Science and Information Quality Shaanxi Engineering Research Center of Medical and Health Big DataXi’an Jiaotong UniversityXi’an710049China

Genotyping of structural variations considering copy number variations(CNVs)is an infancy and challenging ***,a prevalent form of critical genetic variations that cause abnormal copy numbers of large genomic regions in cells,often affect transcription and contribute to a variety of *** characteristics of CNVs often lead to the ambiguity and confusion of existing genotyping features and algorithms,which may cause heterozygous variations to be erroneously genotyped as homozygous variations and seriously affect the accuracy of downstream *** the allelic copy number increases,the error rate of genotyping increases *** instances with different copy numbers play an auxiliary role in the genotyping classification problem,but some will seriously interfere with the accuracy of the *** by these,we propose a transfer learning-based method to genotype structural variations accurately considering *** method first divides the instances with different allelic copy numbers and trains the basic machine learning framework with different genotype *** maximizes the weights of the instances that contribute to classification and minimizes the weights of the instances that hinder correct *** adjusting the weights of the instances with different allelic copy numbers,the contribution of all the instances to genotyping can be maximized,and the genotyping errors of heterozygote variations caused by CNVs can be *** applied the proposed method to both the simulated and real datasets,and compared it to some popular algorithms including GATK,Facets and *** experimental results demonstrate that the proposed method outperforms the others in terms of accuracy,stability and *** source codes have been uploaded at github/TrinaZ/CNVtransfer for academic use only.

关键词： genotyping copy number variations transfer earning

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Enhancing Knee Contact Force Prediction Using Transformer Networks: A Comparative Study with Lstm and Mlp

SSRN

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SSRN 2025年

作者： Xu, Fashu Wang, Junqing Tong, Bingkui Fang, Xuyi Zhang, Hui Deng, Tao Wei, Qu Nie, Yong Li, Kang Department of Orthopedic Surgery West China Biomedical Big Data Center West China Hospital Sichuan University Sichuan Chengdu China Department of Orthopedic Surgery Orthopedic Research Institute West China Hospital Sichuan University Sichuan Chengdu China State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences Liaoning Shenyang China College of Computer Science Sichuan University Sichuan Chengdu China College of Electrical Engineering Sichuan University Sichuan Chengdu China School of Mechanical Engineering Sichuan University Sichuan Chengdu China

Background and objectiveKnee contact force (KCF) is pivotal in both the study and degenerative pathologies like Knee Osteoarthritis. Traditionally, they are primarily estimated using musculoskeletal modeling and machine learning predictive algorithms. However, musculoskeletal modeling is limited by intricate experimental protocols, prohibitive equipment cost, and scalability challenges. While machine learning methods, though computationally efficient, exhibit suboptimal predictive accuracy. This study innovatively developed a Transformer model for predicting KCF, benchmarked against long short-term memory (LSTM) and multilayer perceptron (MLP) *** comprehensive database was constructed with gait data from 513 participants, incorporating three degrees of freedom of hip, knee flexion/extension, and ankle dorsiflexion/plantarflexion, constituting four input combinations for the models. Contact forces derived from OpenSim served as the ground truth. Root mean square error (RMSE) and coefficient of determination (R2) were used to evaluate the performance of *** results indicated that the Transformer model demonstrated superior performance, achieving a significantly lower mean root mean square error of 0.02 body weight (BW) compared to MLP (0.54 BW) and LSTM (0.45 BW). Furthermore, the mean R2 of the Transformer network (0.99) was markedly superior to that of MLP (0.45) and LSTM (0.58).ConclusionsThe application of Transformer networks significantly improved the accuracy of KCF prediction, addressing the limitations of traditional musculoskeletal modeling and existing machine learning approaches, which was of paramount importance in both clinical practice and biomechanical research. © 2025, The Authors. All rights reserved.

关键词： Mean square error

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A Consensus Privacy Metrics Framework for Synthetic data

arXiv

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arXiv 2025年

作者： Pilgram, Lisa Dankar, Fida K. Drechsler, Jörg Elliot, Mark Domingo-Ferrer, Josep Francis, Paul Kantarcioglu, Murat Kong, Linglong Malin, Bradley Muralidhar, Krishnamurty Myles, Puja Prasser, Fabian Raisaro, Jean Louis Yan, Chao El Emam, Khaled School of Epidemiology and Public Health University of Ottawa ON Canada CHEO Research Institute ON Canada Department of Nephrology and Medical Intensive Care Charité – Universitätsmedizin Berlin Berlin Germany Department for Statistical Methods Institute for Employment Research Nuernberg Germany Institute for Statistics Ludwig-Maximilians-Universität Munich Germany Joint Program in Survey Methodology University of Maryland United States The Cathie Marsh Institute Research School of Social Sciences University of Manchester Manchester United Kingdom Department of Computer Engineering and Mathematics Universitat Rovira i Virgili Catalonia Tarragona Spain Max Planck Institute for Software Systems Germany Department of Computer Science Virginia Tech United States Department of Mathematical and Statistical Sciences University of Alberta Alberta Canada Department of Biomedical Informatics Vanderbilt University Medical Center NashvilleTN United States Department of Biostatistics Vanderbilt University Medical Center NashvilleTN United States Department of Computer Science Vanderbilt University NashvilleTN United States Department of Marketing and Supply Chain Management University of Oklahoma Oklahoma United States Medicines and Healthcare products Regulatory Agency London United Kingdom Berlin Institute of Health at Charité Universitätsmedizin Berlin Medical Informatics Group Berlin Germany Biomedical Data Science Center University Hospital Lausanne Lausanne Switzerland

Synthetic data generation is one approach for sharing individual-level data. However, to meet legislative requirements, it is necessary to demonstrate that the individuals’ privacy is adequately protected. There is no consolidated standard for measuring privacy in synthetic data. Through an expert panel and consensus process, we developed a framework for evaluating privacy in synthetic data. Our findings indicate that current similarity metrics fail to measure identity disclosure, and their use is discouraged. For differentially private synthetic data, a privacy budget other than close to zero was not considered interpretable. There was consensus on the importance of membership and attribute disclosure, both of which involve inferring personal information about an individual without necessarily revealing their identity. The resultant framework provides precise recommendations for metrics that address these types of disclosures effectively. Our findings further present specific opportunities for future research that can help with widespread adoption of synthetic data. © 2025, CC BY.

关键词： Differential privacy

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Synthesis of churros-like V2Se9 nanostructures for ultrasensitive electrochemical detection of oxalic acid in urine with portable point-of-care diagnostic devices

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Biosensors and Bioelectronics 2025年 285卷 117589页

作者： Shi, Peizheng Ye, Chen Sun, Zhuang Sun, Kaiqiang Zhao, Ningbin Pourfakhr, Mahan Cai, Tao Nishimura, Kazuhito Jiang, Nan Tsai, Hsu-Sheng Wu, Lidong Wu, Wenqi Yu, Jiancheng Fu, Li Xu, Lixin Chen, Jun Lin, Cheng-Te College of Materials Science and Engineering Zhejiang University of Technology Hangzhou310014 China Qianwan Institute of CNITECH Ningbo315336 China State Key Laboratory of Advanced Marine Materials Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo315201 China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Beijing100049 China Department of Bioengineering University of California Los AngelesCA90095 United States School of Physics Harbin Institute of Technology Harbin150001 China Key Laboratory of Control of Quality and Safety for Aquatic Products Chinese Academy of Fishery Sciences Beijing100141 China Department of Urology The Second Affiliated Hospital of Guangzhou Medical University Guangdong 510260 China Guangdong Key Laboratory of Urology Guangzhou Medical University Guangdong 511495 China Institute of Mass Spectrometry Zhejiang Engineering Research Center of Advanced Mass Spectrometry and Clinical Application Ningbo University Ningbo315211 China Zhenhai Institute of Mass Spectrometry Ningbo315211 China Faculty of Electrical Engineering and Computer Science Ningbo University Ningbo315211 China College of Materials and Environmental Engineering Hangzhou Dianzi University Hangzhou310018 China

The binding of oxalic acid (OA) with metal ions, particularly calcium ions, is a key factor in kidney stone formation, as it produces insoluble calcium oxalate, which crystallizes and accumulates in the kidneys. Consequently, OA in urine is commonly considered a significant biomarker for clinical diagnosis and early screening of kidney stones. This study reports churros-like V2Se9 nanostructures synthesized using a solvothermal method (high pressure and temperature) for sensitive and selective electrochemical detection of OA in urine. The electrodes made of churros-like V2Se9 hybridized with reduced graphene oxide (rGO) for OA recognition, demonstrated a linear range from 20 nM to 4 mM, with an extremely low detection limit of 9.7 nM. To enable fast, user friendly, and accurate point-of-care testing (POCT) for OA in urine samples, we designed and developed a portable workstation integrated with smartphone for data visualization. This is the first study to utilize the V2Se9 system for highly sensitive biosensor applications, highlighting its potential to advance screening techniques for key indicators of kidney stones by incorporating novel transition metal chalcogenide nanomaterials in POCT devices. © 2025 Elsevier B.V.

关键词： Electrochemical biosensors

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Video Stabilization via Prediction with Time-Series Network and Image Inpainting with Pyramid Fusion

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Chinese Journal of Electronics 2021年第6期30卷 1103-1110页

作者： CHENG Keyang LI Shichao RONG Lan WANG Wenshan SHI Wenxi ZHAN Yongzhao School of Computer Science and Communication Engineering Jiangsu University Jiangsu Province Big Data Ubiquitous Perception and Intelligent Agricultural Application Engineering Research Center Cyber Space Security Academy of Jiangsu University National Engineering Laboratory for Public Safety Risk Perception and Control by Big Data Xinjiang Lianhaichuangzhi Information Technology Co. Ltd.

Due to the poor filling effect of the video image defect commonly used in the video stabilization field, the video is seemed still unstable after the image stabilization process, which seriously affects the visual effect. To solve this problem, we improve a video stabilization method based on time-series network prediction and pyramid fusion restoration is proposed to optimize the visual effect after image *** flow of the proposed method is as follows: First,it is adaptive to determine whether the defect of the corresponding frame at the current time needs padding inpainting. Then, for the frame that needs to be inpainting,the frames generated before the current moment are sent to the model combining the convolutional neural networks and the gate recurrent unit to predict the part to be filled. Next the current defect image and the complete image to be filled are brought into the Laplacian pyramid reconstruction, and the improved weighted optimal suture is introduced for splicing during the fusion. Finally, the video frame is cut after reconstruction. The method is tested on a data set composed of videos commonly used in the field of video stabilization. The experimental results show that the average peak signal to noise ratio of the method is 2 to 5 d B higher than that of the comparison algorithm, and the average structural similarity index is improved by about 2% to 7% compared with the contrast algorithm.

关键词： image restoration image sequences video frame cutting improved weighted optimal suture gate recurrent unit video signal processing video stabilization method image fusion Laplacian pyramid reconstruction padding inpainting image resolution neural nets convolutional neural networks video image defect pyramid fusion restoration image inpainting visual effect optimization image reconstruction time-series network prediction image stabilization process

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