Feature selection has been an active area of research which aims at identifying the most optimal subset of features that improves classification accuracy. Medical datasets contain numerous input features and require h...
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We obtain an exact solution of spherically symmetric Letelier AdS black holes immersed in perfect fluid dark matter (PFDM). Considering the cosmological constant as the positive pressure of the system and volume as it...
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Rabies, caused by the neurotropic rabies virus, remains a significant public health concern worldwide. It remains a deadly zoonotic disease with a near 100 % fatality rate once clinical symptoms manifest, causing abou...
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Rabies, caused by the neurotropic rabies virus, remains a significant public health concern worldwide. It remains a deadly zoonotic disease with a near 100 % fatality rate once clinical symptoms manifest, causing about 59,000 deaths annually, of which 59.6 % occur in Asia and 36.4 % in Africa. Dog-mediated rabies accounts for over 99 % of human cases. This review provides a comprehensive overview of rabies, covering its epidemiology, pathogenesis, Etiology, and developments in rabies vaccines. Once the virus enters the body through the bite of an infected animal it travels via peripheral nerves to the central nervous system, leading to fatal encephalitis if left untreated. Vaccination of domestic animals plays a pivotal role in preventing transmission to humans. Post-exposure prophylaxis (PEP) remains the cornerstone of rabies prevention in individuals exposed to potentially infected animals, comprising rabies vaccine and Rabies immunoglobulin administration. Advances in molecular virology have shed light on the pathogenesis of rabies, revealing the intricate interactions between the virus and the host immune system. Despite decades of research, treatment options for established rabies infection remain limited, emphasizing the importance of preventive measures. Experimental therapies, including monoclonal antibodies and novel antiviral agents, promise to improve outcomes in rabies patients. Regardless of the established efficacy of rabies vaccines, challenges remain in ensuring widespread accessibility and coverage, particularly in resource-limited regions. Strategies to enhance pre-exposure prophylaxis with affordable vaccine delivery are essential for achieving global rabies control and elimination goals, underscoring the need for sustained surveillance, vaccination, and public awareness efforts. Continued research into the virology and immunology of rabies is essential for the development of novel interventions to combat this deadly disease.
With the advancement in the digital technologies, the internet has become major break-through and has been universally acceptable technology by the people of all the ages. They use the internet for the purpose of ente...
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Money laundering is a worrying term for every country’s economy these days. Leading economists of all major developed and developing economies are concerned to devise methods to prevent it. The economy of a country i...
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Scale-Free social network is universally popular among the users of almost all the ages. This scale-free network follows the Power Law that expresses the distribution of data in the form of body and tail. Tail can be ...
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Recently, machine learning methods have been successfully used for the prediction of cardiovascular disease. Early diagnosis and prediction is necessary for giving effective treatment to avoid higher mortality rates. ...
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Recently, machine learning methods have been successfully used for the prediction of cardiovascular disease. Early diagnosis and prediction is necessary for giving effective treatment to avoid higher mortality rates. Several classification algorithms have been developed recently which satisfy the need, but show limited accuracy while predicting the heart disease. Hence, the focus of this study is on early prediction of heart disease and to improve the accuracy of prediction using benchmark heart disease datasets such as UCI Cleveland dataset and Heart disease clinical dataset by implementing effective classification and optimization algorithms. Optimization algorithms generally exhibit the benefit of dealing with complex non-linear issues with better adaptability and flexibility. The Emperor penguin optimization algorithm, which can select the best features for classification has been utilized in this study to improve the efficiency, minimize reconstruction errors, and increase the quality of heart disease classification. Further, the newly developed stacked sparse convolutional neural network based auto encoder (SSC-AE) classification algorithm has been employed for significant feature classification with higher robustness and efficacy. Accuracy, Area Under Curve (AUC), and F1 score are some of the measures used to compare the outcomes of several machine learning algorithms to those of the proposed model in this study. The results show that the proposed model, SSC-AE, is superior to other classification models.
Nowadays, deep learning is playing an important role in the domain of image classification. In this paper, a Python library known as Keras, is used for classification of MNIST dataset, a database with images of handwr...
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Successful applications of deep learning (DL) requires large amount of annotated data. This often restricts the benefits of employing DL to businesses and individuals with large budgets for data-collection and computa...
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