检索结果-内蒙古大学图书馆

2021 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2021

作者： Kim, Inyoung Lee, Sangseon Kim, Youngkuk Namkoong, Hugh Kim, Sun Artificial Intelligence Institute Seoul National University Seoul Korea Republic of Institute of Computer Technology Seoul National University Seoul Korea Republic of Seoul National University Department of Computer Science and Engineering Seoul Korea Republic of Institute of Engineering Research Seoul National University Seoul Korea Republic of Interdisciplinary Program in Bioinformatics Seoul National University Seoul Korea Republic of

ISBN: (纸本)9781665401265

Breast cancer is classified into five intrinsic subtypes, with differing treatment methods and prognoses. Therefore, accurate identification of subtypes from patient transcriptome data is essential. Many gene signatures, including PAM50, have been developed to classify breast cancer subtypes. However, existing gene selection methods do not utilize biological pathways. Gene signature selection using biological pathways can explain signature genes in terms of biological functions. Thus, we propose a probabilistic model for pathway-guided gene set selection using gene expression data. First, we defined gene and pathway factors based on gene expression and pathway activation levels, and calculated the posterior probability. Second, we adopted the prediction strength to guide gene set selection. Third, the gene set was selected using the posterior probability and prediction strength values. Finally, on evaluating the selected gene set, it was experimentally confirmed that our gene set performed better on classification tasks than the PAM50 gene set, a gene set produced by the XGBoost classifier, and a random gene set. Among the genes selected by our method, it was confirmed that the genes included in the cell cycle and circadian rhythm pathways showed different expression patterns for each breast cancer subtype. Our selected gene set exhibited biological significance in terms of pathway activation. © 2021 IEEE.

关键词： Gene expression

来源：评论

学校读者我要写书评

暂无评论

Adaptive Curriculum Learning for Semi-supervised Segmentation of 3D CT-Scans 28th

Adaptive Curriculum Learning for Semi-supervised Segmentati...

引用

28th International Conference on Neural Information Processing, ICONIP 2021

作者： Nartey, Obed Tettey Yang, Guowu Agyapong, Dorothy Araba Yakoba Wu, JinZhao Sarpong, Asare K. Frempong, Lady Nadia Big Data Research Center School of Computer Science and Engineering University of Electronic Science and Technology of China Chengdu611731 China The School of Computer Science and Electronic Information Guangxi University Nanning530004 China Biomedical Engineering Program Kwame Nkrumah University of Science and Technology Kumasi Ghana School of Information and Software Engineering University of Electronic Science and Technology of China Chengdu China School of Medicine Department of Radiology and Imaging Sciences Emory University 1364 Clitton Rd. AtlantaGA30322 United States

ISBN: (纸本)9783030921842

Semi-supervised learning algorithms make use of both labelled training data and unlabelled data. However, the visual domain gap between these sets poses a challenge which prevents deep learning models from obtaining the results they have achieved most especially in the field of medical imaging. Recently, self-training with deep learning has become a powerful approach to leverage labelled training and unlabelled data. However, a challenge of generating noisy pseudo-labels and placing over-confident labelling belief on incorrect classes leads to deviation from the solution. To solve this challenge, the study investigates a curriculum-styled approach for deep semi-supervised segmentation which relaxes and treats pseudo-labels as continuous hidden variables by developing an adaptive pseudo-label generation strategy to jointly optimized the pseudo-label generation and selection process. A regularization scheme is further proposed to smoothen the probability outputs and sharpen the less represented pseudo-label regions. The proposed method was evaluated on three publicly available computer Tomography (CT) scan benchmarks and extensive experiments on all modules have demonstrated the efficacy of the proposed method. © 2021, Springer Nature Switzerland AG.

关键词： Curricula

来源：评论

学校读者我要写书评

暂无评论

Naked-eye observation of water-forming reaction on palladium etalon:transduction of gas-matter reaction into light-matter interaction

引用

PhotoniX 2023年第1期4卷 349-363页

作者： Jongsu Lee Eui-Sang Yu Taehyun Kim In Soo Kim Seok Chung Seung Jae Kwak Won Bo Lee Yusin Pak Yong-Sang Ryu Sensor System Research Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea Department of Electrical and Computer Engineering Seoul National UniversitySeoul 08826Republic of Korea Smart Materials Research Section Electronics and Telecommunications Research InstituteDaejeon 34129Republic of Korea Department of Micro/Nano Systems Korea University02841 SeoulRepublic of Korea Nanophotonics Research Center Korea Institute of Science and TechnologySeoul 02792Republic of Korea School of Mechanical Engineering Korea UniversitySeoul 02841Republic of Korea School of Chemical and Biological Engineering Seoul National UniversitySeoul 08826Republic of Korea Interdisciplinary Program in Precision Public Health Korea UniversitySeoul 02481Republic of Korea School of Biomedical Engineering Korea UniversitySeoul 02481Republic of Korea

Palladium is the most prominent material in both scientific and industrial research on gas storage,purification,detection,and catalysis due to its unique properties as a catalyst and hydrogen *** the dynamic optical phenomena of palladium reacting with hydrogen,transduction of the gas-matter reaction into light-matter interaction is attempted to visualize the dynamic surface chemistry and reaction *** simple geometry of the metal-dielectric-metal structure,Fabry-Perot etalon,is employed for a colorimetric reactor,to display the catalytic reaction of the exposed gas via water-film/bubble formation at the dielectric/palladium *** adsorption/desorption behavior and catalytic reaction of hydrogen and oxygen on the palladium surface display highly repeatable and dramatic color changes based on two distinct water formation trends:the foggy effect by water bubbles and the whiteout effect by water film *** and experiments demonstrate the robustness of the proposed Fabry-Perot etalon as an excellent platform for monitoring the opto-physical phenomena driven by heterogeneous catalysis.

关键词： Palladium Hydrogen Oxygen Fabry-Perot resonators Colorimetric sensors Water-forming reaction

来源：评论

学校读者我要写书评

暂无评论

AutoSNN: Towards Energy-Efficient Spiking Neural Networks

arXiv

引用

arXiv 2022年

作者： Na, Byunggook Mok, Jisoo Park, Seongsik Lee, Dongjin Choe, Hyeokjun Yoon, Sungroh Samsung Advanced Institute of Technology Korea Republic of Department of Electric and Computer Engineering Seoul National University Korea Republic of Korea Institute of Science and Technology Korea Republic of Interdisciplinary Program in Artificial Intelligence Seoul National University Korea Republic of

Spiking neural networks (SNNs) that mimic information transmission in the brain can energy-efficiently process spatio-temporal information through discrete and sparse spikes, thereby receiving considerable attention. To improve accuracy and energy efficiency of SNNs, most previous studies have focused solely on training methods, and the effect of architecture has rarely been studied. We investigate the design choices used in the previous studies in terms of the accuracy and number of spikes and figure out that they are not best-suited for SNNs. To further improve the accuracy and reduce the spikes generated by SNNs, we propose a spike-aware neural architecture search framework called AutoSNN. We define a search space consisting of architectures without undesirable design choices. To enable the spike-aware architecture search, we introduce a fitness that considers both the accuracy and number of spikes. AutoSNN successfully searches for SNN architectures that outperform hand-crafted SNNs in accuracy and energy efficiency. We thoroughly demonstrate the effectiveness of AutoSNN on various datasets including neuromorphic datasets. © 2022, CC BY-NC-ND.

关键词： Energy efficiency

来源：评论

学校读者我要写书评

暂无评论

Cross-system biological image quality enhancement based on the generative adversarial network as a foundation for establishing a multi-institute microscopy cooperative network

arXiv

引用

arXiv 2024年

作者： Panek, Dominik Rząca, Carina Szczypior, Maksymilian Sorysz, Joanna Misztal, Krzysztof Baster, Zbigniew Rajfur, Zenon Doctoral School of Exact and Natural Sciences Jagiellonian University ul. Lojasiewicza 11 Kraków30-348 Poland Department of Molecular and Interfacial Biophysics Faculty of Physics Astronomy and Applied Computer Science Jagiellonian University ul. Lojasiewicza 11 Kraków30‑348 Poland Undergraduate Program in Biophysics Faculty of Physics Astronomy and Applied Computer Science Jagiellonian University ul. Lojasiewicza 11 Kraków30‑348 Poland Undergraduate program in Biomedical Engineering Faculty of Electrical Engineering Automatics Computer Science and Biomedical Engineering AGH University of Science and Technology Al. A. Mickiewicza 30 Building B-1 Kraków30-059 Poland Division of Computational Mathematics Faculty of Mathematics and Computer Science Jagiellonian University 6 Lojasiewicza St. Kraków Poland

High-quality fluorescence imaging of biological systems is limited by processes like photobleaching and phototoxicity, and also in many cases, by limited access to the latest generations of microscopes. Moreover, low temporal resolution can lead to a motion blur effect in living systems. Our work presents a deep learning (DL) generative-adversarial approach to the problem of obtaining high-quality (HQ) images based on their low-quality (LQ) equivalents. We propose a generative-adversarial network (GAN) for contrast transfer between two different separate microscopy systems: a confocal microscope (producing HQ images) and a wide-field fluorescence microscope (producing LQ images). Our model proves that such transfer is possible, allowing us to receive HQ-generated images characterized by low mean squared error (MSE) values, high structural similarity index (SSIM), and high peak signal-to-noise ratio (PSNR) values. For our best model in the case of comparing HQ-generated images and HQ-ground truth images, the median values of the metrics are 6·10-4, 0.9413, and 31.87, for MSE, SSIM, and PSNR, respectively. In contrast, in the case of comparison between LQ and HQ ground truth median values of the metrics are equal to 0.0071, 0.8304, and 21.48 for MSE, SSIM, and PSNR respectively. Therefore, we observe a significant increase ranging from 14% to 49% for SSIM and PSNR respectively. These results, together with other single-system cross-modality studies, provide proof of concept for further implementation of a cross-system biological image quality enhancement. © 2024, CC BY-SA.

关键词： Fluorescence imaging

来源：评论

学校读者我要写书评

暂无评论

Nonsaturated large magnetoresistance and transport dynamics in a n-doped cryogenic WSe2 field-effect device

引用

Physical Review B 2025年第12期111卷 125307-125307页

作者： Wei-Chen Lin Ching-Chen Yeh Jia-Zhu Zou Nhat Anh Nguyen Phan Inayat Uddin Hai Yen Le Thi Kenji Watanabe Takashi Taniguchi Gil-Ho Kim Department of Engineering and System Science National Tsing Hua University Hsinchu 300 Taiwan Taiwan International Graduate Program Academia Sinica Taipei 115 Taiwan Department of Physics National Taiwan University Taipei 106 Taiwan Department of Electrical and Computer Engineering Sungkyunkwan University (SKKU) Suwon 164 Republic of Korea Sungkyunkwan Advanced Institute of Nano Technology (SAINT) Sungkyunkwan University (SKKU) Suwon 16419 Republic of Korea Research Center for Electronic and Optical Materials National Institute for Materials Science 1-1 Namiki Tsukuba 305-0044 Japan Research Center for Materials Nanoarchitectonics National Institute for Materials Science 1-1 Namiki Tsukuba 305-0044 Japan

Interest in the two-dimensional (2D) semiconducting transition metal dichalcogenides (TMDs) continues to intensify, driven by their suitable band gaps to supplant silicon as next-generation semiconductor materials. Among various TMDs, tungsten diselenide (WSe2) is renowned for its superior electrical properties in carrier density and mobility under ambient conditions. Despite its notable attributes, the behavior of monolayer WSe2 in the electron-doped regime under cryogenic conditions remains largely uncharted, particularly concerning its magnetotransport properties. In this study, we reveal the transport mechanisms of monolayer WSe2 from high temperatures down to the cryogenic regime. As evident by Efros–Shklovskii variable-range hopping (E-S VRH) in the cryogenic regime, strong Coulomb interactions arise between electrons. Above 8 K, an uncommon nonsaturated quadratic large magnetoresistance (MR) can be explained by the wave-function shrinkage model, which is consistent with the E-S VRH transport mechanism. Notably, the nonsaturated quadratic large MR shows a magnitude up to 1740% at 13 T. These findings underscore the potential applications for monolayer WSe2 in cryogenic field-effect devices, magnetic sensors, and memory devices and mark a significant advance in magnetotransport research.

关键词： Monolayers

来源：评论

学校读者我要写书评

暂无评论

Spatial atlas of the mouse central nervous system at molecular resolution (vol 622, pg 552, 2023)

引用

NATURE 2024年第7993期625卷 E6-E6页

作者： Shi, Hailing He, Yichun Zhou, Yiming Huang, Jiahao Maher, Kamal Wang, Brandon Tang, Zefang Luo, Shuchen Tan, Peng Wu, Morgan Lin, Zuwan Ren, Jingyi Thapa, Yaman Tang, Xin Chan, Ken Y. Deverman, Benjamin E. Shen, Hao Liu, Albert Liu, Jia Wang, Xiao Broad Institute of MIT and Harvard Cambridge MA USA Department of Chemistry Massachusetts Institute of Technology Cambridge MA USA John A. Paulson School of Engineering and Applied Sciences Harvard University Boston MA USA Computational and Systems Biology PhD Program Massachusetts Institute of Technology Cambridge MA USA Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology Cambridge MA USA Department of Biology Massachusetts Institute of Technology Cambridge MA USA Klarman Cell Observatory Broad Institute of MIT and Harvard Cambridge MA USA Department of Chemistry and Chemical Biology Harvard University Cambridge MA USA Stanley Center for Psychiatric Research Broad Institute of MIT and Harvard Cambridge MA USA

来源：评论

学校读者我要写书评

暂无评论

AI in Industry: Real-World Applications and Case Studies

TechRxiv

引用

TechRxiv 2023年

作者： Rahmaniar, Wahyu Maarif, Alfian ul Haq, Qazi Mazhar Iskandar, Muchammad Edo Institute of Innovative Research Tokyo Institute of Technology Kanagawa226-8503 Japan Department of Electrical Engineering Universitas Ahmad Dahlan Yogyakarta55166 Indonesia International Bachelor Program in Informatics and Computer Science Yuan Ze University Taoyuan320315 Taiwan Ezy Industries Jakarta Indonesia

Artificial intelligence (AI) has advanced rapidly and is becoming a cornerstone technology that drives innovation and efficiency in various industries. This paper examines the real-world application of AI in multiple sectors, including healthcare, finance, agriculture, retail, energy, and automotive. Several case studies are described to understand better the practical applications, results, and challenges of implementing AI. While many industries have reaped enormous benefits from AI, inherent challenges include data privacy, the potential for bias, and the continuing demand for skilled labor. This comprehensive review aims to provide AI application insights to professionals and researchers. Thus, as AI grows, there may be challenges and avenues for future research. © 2023, CC BY.

关键词： Agriculture

来源：评论

学校读者我要写书评

暂无评论

Picosecond optical-to-x-ray (Cd,Mg)Te radiation detectors

Picosecond optical-to-x-ray (Cd,Mg)Te radiation detectors

引用

Conference on Lasers and Electro-Optics (CLEO)

作者： J. Cheng I. Komissarov G. Chen D. Chakraborty S. Kutcher H. Chen S. Trivedi Roman Sobolewski Materials Science Graduate Program University of Rochester Rochester New York USA Laboratory for Laser Energetics University of Rochester Rochester New York USA Department of Electrical and Computer Engineering University of Rochester Rochester New York USA Brimrose Technology Corp Sparks Maryland USA

We developed a dual optical/x-ray ultrafast photodetector based on in-house grown Cd 0.97 Mg 0.03 Te single crystals. The detector is characterized by ~200 ps full-width-at-half-maximum, readout-electronics limited p... 详细信息

ISBN: (纸本)9781957171258

关键词： Femtosecond lasers Photodetectors Photon counting Pump probe spectroscopy Radiation detectors Ti:sapphire lasers

来源：评论

学校读者我要写书评

暂无评论

Cell2Sentence: Teaching Large Language Models the Language of Biology 41

Cell2Sentence: Teaching Large Language Models the Language o...

引用

41st International Conference on Machine Learning, ICML 2024

作者： Levine, Daniel Rizvi, Syed Asad Lévy, Sacha Pallikkavaliyaveetil, Nazreen Zhang, David Chen, Xingyu Ghadermarzi, Sina Wu, Ruiming Zheng, Zihe Vrkic, Ivan Zhong, Anna Raskin, Daphne Han, Insu de Oliveira Fonseca, Antonio Henrique Caro, Josue Ortega Karbasi, Amin Dhodapkar, Rahul M. van Dijk, David Department of Computer Science Yale University New HavenCT United States School of Engineering Applied Science University of Pennsylvania PhiladelphiaPA United States School of Computer and Communication Sciences Swiss Federal Institute of Technology Lausanne Lausanne Switzerland Department of Neuroscience Yale School of Medicine New HavenCT United States Wu Tsai Institute Yale University New HavenCT United States Google United States Yale Institute for Foundations of Data Science New HavenCT United States Yale School of Engineering and Applied Science New HavenCT United States Roski Eye Institute University of Southern California Los AngelesCA United States Yale School of Medicine New HavenCT United States Cardiovascular Research Center Yale School of Medicine New HavenCT United States Interdepartmental Program in Computational Biology & Bioinformatics Yale University New HavenCT United States

We introduce Cell2Sentence (C2S), a novel method to directly adapt large language models to a biological context, specifically single-cell transcriptomics. By transforming gene expression data into"cell sentences," C2S bridges the gap between natural language processing and biology. We demonstrate cell sentences enable the finetuning of language models for diverse tasks in biology, including cell generation, complex cell-type annotation, and direct data-driven text generation. Our experiments reveal that GPT-2, when fine-tuned with C2S, can generate biologically valid cells based on cell type inputs, and accurately predict cell types from cell sentences. This illustrates that language models, through C2S finetuning, can acquire a significant understanding of single-cell biology while maintaining robust text generation capabilities. C2S offers a flexible, accessible framework to integrate natural language processing with transcriptomics, utilizing existing models and libraries for a wide range of biological applications. Copyright 2024 by the author(s)

关键词： Gene expression

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：