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Practical Iterative Quantum Consensus Protocol with Sharding Construction

IEEE Journal on Selected Areas in Communications 2025年

作者： Ying, Chenhao Du, Yuxuan Zhang, Weiting Jiang, Xikun Wang, Gang Jin, Haiming Li, Jie Luo, Yuan Tao, Dacheng Shanghai Jiao Tong University Department of Computer Science Shanghai China Zhejiang University Shanghai Jiao Tong University State Key Laboratory of Blockchain and Data Security Blockchain Advanced Research Center Jiangsu Wuxi214101 China Nanyang Technological University College of Computing&Data Science Singapore Beijing Jiaotong University School of Electronic and Information Engineering Beijing China University of Copenhagen Department of Computer Science Denmark Northeastern University School of Computer Science and Engineering Shenyang China Shanghai Key Laboratory of Trusted Data Circulation and Governance Web3 China

With the development of quantum blockchain, the quantum consensus protocols have garnered increasing attention, which play a crucial role in driving the implementation of quantum blockchains. However, existing protocols, derived from the classical consensus algorithms, face practical application challenges due to current quantum technology limitations. The first challenge is the bottleneck in generating large-scale entangled quantum states. The second challenge arises from the generation of malicious quantum states. The final challenge involves privacy concerns. To address these challenges, we propose a practical iterative QUantum consensus protocol with sharding construction, namely, Q-Union. In fact, Q-Union employs an iterative consensus algorithm where participating nodes are divided into multiple smaller shards, with the consensus process occurring within the current shard, and new shards are involved only if consensus is not achieved. Leveraging Greenberger-Horne- Zeilinge states and Aharonov states, Q-Union harnesses the advantages of quantum mechanics to achieve anonymous consensus, protecting the private information of participating nodes. Additionally, by integrating state verification, Q-Union ensures the correctness of the consensus procedure in the presence of malicious nodes generating adversarial quantum states. Finally, it is proven that Q-Union can also defend against Byzantine attacks from adversarial nodes, maintaining the same security level as traditional non-sharded consensus protocols. Specifically, it consistently outputs the correct consensus when the fraction of adversaries among participating nodes is less than 1/2 with synchronous communication. Both the theoretical analysis and performance illustration demonstrate the superior performance of the proposed Q-Union compared to state-of-the-art protocols. © 1983-2012 IEEE.

关键词： Quantum entanglement

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Pointgs: Bridging and Fusing Geometric and Semantic Space for 3d Point Cloud Analysis

SSRN

引用

SSRN 2022年

作者： Jiang, Chenru Huang, Kaizhu Wu, Junwei Wang, Xinheng Xiao, Jimin Hussain, Amir Department of Computer Science University of Liverpool LiverpoolL69 7ZX United Kingdom Data Science Research Center Duke Kunshan University No. 8 Duke Avenue Kunshan215316 China Department of Electrical and Electronic Engineering Xi’an Jiaotong-Liverpool University Suzhou215123 China School of Computing Edinburgh Napier University EdinburghEH11 4BN United Kingdom

Directly processing 3D point cloud data becomes dominant in classification and segmentation tasks. Present mainstream point based methods usually focus on learning in either geometric space ( i.e. PointNet++) or semantic space ( i.e. DGCNN). Owing to the irregular and unordered data property of point cloud, these methods still suffer from drawbacks of either ambiguous local features aggregation in geometric space or poor global features extraction in semantic space. While few prior works address these two defects simultaneously by fusing information from the dual spaces, we make a first attempt to develop a synergistic framework, called PointGS. Leveraging both the strength of geometric structure and semantic representation, PointGS establishes a mutual supervision mechanism that can bridge the two spaces and fuse complementary information for better analyzing 3D point cloud data. Compared with existing popular networks, our work attains obvious performance improvement on all three mainstream tasks without any sophisticated operations. © 2022, The Authors. All rights reserved.

关键词： Semantics

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FedEMA: Federated Exponential Moving Averaging with Negative Entropy Regularizer in Autonomous Driving

arXiv

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arXiv 2025年

作者： Kou, Wei-Bin Zhu, Guangxu Cheng, Bingyang Wang, Shuai Tang, Ming Wu, Yik-Chung Department of Electrical and Electronic Engineering The University of Hong Kong Hong Kong Department of Computer Science and Engineering Southern University of Science and Technology Shenzhen China Shenzhen International Center For Industrial And Applied Mathematics Shenzhen Research Institute of Big Data Shenzhen China Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen China

Street Scene Semantic Understanding (denoted as S3U) is a crucial but complex task for autonomous driving (AD) vehicles. Their inference models typically face poor generalization due to domain-shift. Federated Learning (FL) has emerged as a promising paradigm for enhancing the generalization of AD models through privacy-preserving distributed learning. However, these FL AD models face significant temporal catastrophic forgetting when deployed in dynamically evolving environments, where continuous adaptation causes abrupt erosion of historical knowledge. This paper proposes Federated Exponential Moving Average (FedEMA), a novel framework that addresses this challenge through two integral innovations: (I) Server-side model’s historical fitting capability preservation via fusing current FL round’s aggregation model and a proposed previous FL round’s exponential moving average (EMA) model;(II) Vehicle-side negative entropy regularization to prevent FL models’ possible overfitting to EMA-introduced temporal patterns. Above two strategies empower FedEMA a dual-objective optimization that balances model generalization and adaptability. In addition, we conduct theoretical convergence analysis for the proposed FedEMA. Extensive experiments both on Cityscapes dataset and Camvid dataset demonstrate FedEMA’s superiority over existing approaches, showing 7.12% higher mean Intersection-over-Union (mIoU). © 2025, CC BY-NC-ND.

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Dose-finding design based on level set estimation in phase I cancer clinical trials

arXiv

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arXiv 2025年

作者： Seno, Keiichiro Matsui, Kota Iwazaki, Shogo Inatsu, Yu Takeno, Shion Matsui, Shigeyuki Department of Biostatistics Nagoya University Japan Department of Biostatistics Kyoto University Japan MI-6 Ltd. Department of Computer Science Nagoya Institute of Technology Japan Department of Mechanical Systems Engineering Nagoya University Japan Center for Advanced Intelligence Project RIKEN Japan Research Center for Medical and Health Data Science The Institute of Statistical Mathematics Japan

The primary objective of phase I cancer clinical trials is to evaluate the safety of a new experimental treatment and to find the maximum tolerated dose (MTD). We show that the MTD estimation problem can be regarded as a level set estimation (LSE) problem whose objective is to determine the regions where an unknown function value is above or below a given threshold. Then, we propose a novel dose-finding design in the framework of LSE. The proposed design determines the next dose on the basis of an acquisition function incorporating uncertainty in the posterior distribution of the dose-toxicity curve as well as overdose control. Simulation experiments show that the proposed LSE design achieves a higher accuracy in estimating the MTD and involves a lower risk of overdosing allocation compared to existing designs, thereby indicating that it provides an effective methodology for phase I cancer clinical trial design. © 2025, CC BY.

关键词： Intellectual property core

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Strategic priorities for transformative progress in advancing biology with proteomics and artificial intelligence

arXiv

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arXiv 2025年

作者： Sun, Yingying Jun, A. Liu, Zhiwei Sun, Rui Qian, Liujia Payne, Samuel H. Bittremieux, Wout Ralser, Markus Li, Chen Chen, Yi Dong, Zhen Perez-Riverol, Yasset Khan, Asif Sander, Chris Aebersold, Ruedi Vizcaíno, Juan Antonio Krieger, Jonathan R. Yao, Jianhua Wen, Han Zhang, Linfeng Zhu, Yunping Xuan, Yue Sun, Benjamin Boyang Qiao, Liang Hermjakob, Henning Tang, Haixu Gao, Huanhuan Deng, Yamin Zhong, Qing Chang, Cheng Bandeira, Nuno Li, Ming Weinan, E. Sun, Siqi Yang, Yuedong Omenn, Gilbert S. Zhang, Yue Xu, Ping Fu, Yan Liu, Xiaowen Overall, Christopher M. Wang, Yu Deutsch, Eric W. Chen, Luonan Cox, Jürgen Demichev, Vadim He, Fuchu Huang, Jiaxing Jin, Huilin Liu, Chao Li, Nan Luan, Zhongzhi Song, Jiangning Yu, Kaicheng Wan, Wanggen Wang, Tai Zhang, Kang Zhang, Le Bell, Peter A. Mann, Matthias Zhang, Bing Guo, Tiannan Affiliated Hangzhou First People’s Hospital State Key Laboratory of Medical Proteomics School of Medicine Westlake University Zhejiang Province Hangzhou China Westlake Center for Intelligent Proteomics Westlake Laboratory of Life Sciences and Biomedicine Zhejiang Province Hangzhou China Biology Department Brigham Young University ProvoUT84602 United States Department of Computer Science University of Antwerp Antwerp2020 Belgium Department of Biochemistry CharitéUniversitätsmedizin Berlin Berlin Germany Biomedicine Discovery Institute Department of Biochemistry and Molecular Biology Monash University MelbourneVICVIC 3800 Australia Wellcome Genome Campus Hinxton CambridgeCB10 1SD United Kingdom Harvard Medical School Ludwig Center at Harvard United States Harvard Medical School Broad Institute Ludwig Center at Harvard Dana-Farber Cancer Institute United States Department of Biology Institute of Molecular Systems Biology ETH Zürich Zürich Switzerland Bruker Ltd. MiltonONL9T 6P4 Canada AI for Life Sciences Lab Tencent Shenzhen518057 China State Key Laboratory of Medical Proteomics AI for Science Institute Beijing100080 China Beijing Institute of Lifeomics Beijing102206 China Thermo Fisher Scientific GmbH Hanna-Kunath Str. 11 Bremen28199 Germany Informatics and Predictive Sciences Research Bristol Myers Squibb United States Department of Chemistry Fudan University Songhu Road 2005 Shanghai200438 China Department of Computer Science Luddy School of Informatics Computing and Engineering Indiana University IN47408 United States ProCan® Children’s Medical Research Institute Faculty of Medicine and Health The University of Sydney WestmeadNSW Australia La Jolla CA United States Central China Institute of Artificial Intelligence University of Waterloo Canada AI for Science Institute Center for Machine Learning Research School of Mathematical Sciences Peking University China Research Institute of Intelligent Complex Systems Fudan U

Artificial intelligence (ai) is transforming scientific research, including proteomics. Advances in mass spectrometry (MS)-based proteomics data quality, diversity, and scale, combined with groundbreaking ai techniques, are unlocking new challenges and opportunities in biological discovery. Here, we highlight key areas where ai is driving innovation, from data analysis to new biological insights. These include developing an ai-friendly ecosystem for proteomics data generation, sharing, and analysis;improving peptide and protein identification and quantification;characterizing protein-protein interactions and protein complexes;advancing spatial and perturbation proteomics;integrating multi-omics data;and ultimately enabling ai-empowered virtual cells. © 2025, CC BY.

关键词： Biotic

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Predicting 1-year mortality of acute kidney injury: A risk model using electronic health records

Predicting 1-year mortality of acute kidney injury: A risk m...

引用

International Forum on Medical Imaging in Asia 2021, IFMIA 2021

作者： Huang, Chao-Jung Wu, Brian Li, Xiaodong Han, Yongxia Zhang, Yaqi Hao, Shiying Ling, Xuefeng B. National Taiwan University-Stanford Joint Program Office of AI in Biotechnology Ministry of Science and Technology Joint Research Center for Artificial Intelligence Technology and All Vista Healthcare Taipei Taiwan Clinical Research University of California San Diego San DiegoCA92093 United States School of Computer Science and Technology Hangzhou Dianzi University Hangzhou China School of Electrical Power Engineering South China University of Technology Guangzhou China Department of Surgery Stanford University StanfordCA94305 United States Department of Cardiothoracic Surgery Stanford University StanfordCA94305 United States Clinical and Translational Research Program Betty Irene Moore Children's Heart Center Lucile Packard Children's Hospital Palo AltoCA94305 United States

ISBN: (数字)9781510644212

ISBN: (纸本)9781510644205

Acute kidney injury (AKI) is associated with increased morbidity and mortality in intensive care units (ICU). The sudden episode of kidney failure may lead to end-stage renal disease (ESRD) or deaths, and has been related to significantly increasing costs of ICU admissions and treatments. Early prediction of AKI inpatient mortality will help decision-making, and benefit resource allocation in ICU. Therefore, it is crucial to develop an early warning system for AKI prediction. We aimed to create a more comprehensive predictive model for 1-year AKI mortality. A cohort of 2,247 patients with AKI was assembled, of which the in-hospital mortality was 36.67%. Longitudinal data of each patient were collected from the Medical Information Mart for Intensive Care III (MIMIC-III) dataset. An interpretable XGBoost risk model was developed and validated by 10-fold cross validation. Model predictors included 11 routinely collected AKI-related laboratory measurements, 8 complications of AKI, and demographic data. An artificial neural network (ANN) model was also developed in parallel for comparison. The XGBoost model demonstrated an area under the receiver-operating characteristic curve (AUC) of 0.83, which was superior to ANN (AUC = 0.79). Our model was able to predict mortality of AKI in ICU with high accuracy. Our model can predict 1-year AKI mortality. Furthermore, it had great potential for identifying at-risk patients in ICU. These findings indicated that our approach might offer opportunities for better resource utilization and better administration of AKI. © 2021 SPIE.

关键词： Neural networks

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Differentially-Fed Rectangular Patch Antenna under TM21and TM03Modes for Enhanced Bandwidth and Stable High Gain 13

Differentially-Fed Rectangular Patch Antenna under TM21and T...

引用

13th International Conference on Microwave and Millimeter Wave Technology, ICMMT 2021

作者： Xu, Zhi-Yong Zhang, Xiao Hong, Kai-Dong Zhu, Lei Yuan, Tao Shenzhen University Guangdong Prov. Mobile Terminal Microwave And Millimeter-Wave Antenna Engineering Research Center College Of Electronics And Information Engineering Shenzhen518060 China Guangdong-Hong Kong Joint Laboratory For Big Data Imaging And Communication Shenzhen Guangdong518048 China ATR National Key Laboratory Of Defense Technology College Of Electronics And Information Engineering Shenzhen University Shenzhen Guangdong518060 China Department Of Electrical And Computer Engineering Faculty Of Science And Technology University Of Macau China Postgraduate Education Branch Of The China Education Society Of Electronics China

ISBN: (纸本)9781665434379

A differentially-fed rectangular patch antenna under TM21 and TM03 modes is proposed to realize bandwidth enhancement and stable high gain. Firstly, two open slots along the median of patch are introduced to reconstruct the current distribution of TM21 mode so that its broadside radiation is strengthened greatly. Secondly, another central slot along with the two sided ones interrupt out-of-phase current of TM03 mode and make it circulate with little radiation, hence substantially reducing the sidelobe level (SLL). With the help of loading three cascaded slots and pins, the frequencies of the two modes are merged together, and so the antenna obtains an enhanced impedance bandwidth of 11.8% (2.24-2.52 GHz). Finally, the simulation results show that the proposed rectangular patch antenna achieves gain level as high as 13.8 dBi, which has little variation in the working bandwidth. © 2021 IEEE.

关键词： Bandwidth

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Current Progress and Challenges in Large-scale 3D Mitochondria Instance Segmentation

TechRxiv

引用

TechRxiv 2023年

作者： Franco-Barranco, Daniel Lin, Zudi Jang, Won-Dong Wang, Xueying Shen, Qijia Yin, Wenjie Fan, Yutian Li, Mingxing Chen, Chang Xiong, Zhiwei Xin, Rui Liu, Hao Chen, Huai Li, Zhili Zhao, Jie Chen, Xuejin Pape, Constantin Conrad, Ryan De Folter, Jozefus Nightingale, Luke Jones, Martin L. Liu, Yanling Ziaei, Dorsa Huschauer, Stephan Arganda-Carreras, Ignacio Pfister, Hanspeter Wei, Donglai The Department of Computer Science and Artificial Intelligence University of the Basque Country Donostia-San Sebastian Spain San Sebastian Spain Ikerbasque Basque Foundation for Science Bilbao Spain Biofisika Institute CSIC UPV/EHU Bilbao Spain Harvard University All-ston MA United States The Department of Molecular and Cellular Biology Harvard University CambridgeMA United States The Wellcome Centre for Integrative Neuroimaging FMRIB Nuffield Department of Clinical Neurosciences University of Oxford Oxford United Kingdom University of Science and Technology of China Anhui China The Institute of Image Processing and Pattern Recognition Department of Automation Shanghai Jiao Tong University Shanghai China The National Engineering Laboratory for Brain-inspired Intelligence Technology and Application University of Science and Technology of China Anhui China The Georg-August University Goettingen Germany The Center for Molecular Microscopy Center for Cancer Research National Cancer Institute National Institutes of Health Bethesda United States The Cancer Research Technology Program Frederick National Laboratory for Cancer Research Frederick United States The Francis Crick Institute London United Kingdom The Advanced Biomedical Computational Science Group Frederick National Laboratory for Cancer Research FrederickMD United States The Computer Science Department Boston College Chestnut Hill MA United States

In this paper, we present the results of the MitoEM challenge on mitochondria 3D instance segmentation from electron microscopy images, organized in conjunction with the IEEE-ISBI 2021 conference. Our benchmark dataset consists of two large-scale 3D volumes, one from human and one from rat cortex tissue, which are 3,600 times larger than previously used datasets. At the time of paper submission, 257 participants had registered for the challenge, 14 teams had submitted their results, and six teams participated in the challenge workshop. Here, we present eight top-performing approaches from the challenge participants, along with our own baseline strategies. Posterior to the challenge, annotation errors in the ground truth were corrected without altering the final ranking. Additionally, we present a retrospective evaluation of the scoring system which revealed that (1) the challenge metric was permissive with the false positive predictions and (2) the size-based grouping of instances did not correctly categorize mitochondria of interest. Thus, we propose a new scoring system that better reflects the correctness of the segmentation results. Although several of the top methods are compared favorably to our own baselines, substantial errors remain unsolved for mitochondria with challenging morphologies. Thus, the challenge remains open for submission and automatic evaluation, with all volumes available for download. © 2023, CC BY.

关键词： Electron microscopy

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An improved smith-waterman algorithm based on spark parallelization

引用

International Journal Bioautomation 2019年第1期23卷 117-129页

作者： Liu, Yanfeng Li, Leixiao Gao, Jing College of Data Science and Application Inner Mongolia University of Technology Hohhot010080 China College of Computer and Information Engineering Inner Mongolia Agricultural University Hohhot010018 China Inner Mongolia Autonomous Region Engineering Technology Research Center of Big Data Based Software Service Inner Mongolia University of Technology Hohhot010080 China

This paper proposes the design and the implementation of a Spark parallelization plan for improving the Smith-Waterman (SW) algorithm, named the Spark-OSW algorithm. Then, the Spark-OSW was verified through accuracy, performance and acceleration tests. The results show that the proposed algorithm achieved 100% accuracy, ran much faster than the SW, and performed well in cluster environment. The research findings shed important new light on the database search for gene sequences. © 2019 INT. J. Bioautomation.

关键词： Search engines

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Energy Efficient Train-Ground mmWave Mobile Relay System for High Speed Railways

arXiv

引用

arXiv 2022年

作者： Wang, Lei ai, Bo Niu, Yong Zhong, Zhangdui Mao, Shiwen Wang, Ning Han, Zhu The State Key Laboratory of Rail Traffic Control and Safety Beijing Jiaotong University Beijing100044 China Beijing Engineering Research Center of High-speed Railway Broadband Mobile Communications Beijing Jiaotong University Beijing100044 China Peng Cheng Laboratory Henan Joint International Research Laboratory of Intelligent Networking and Data Analysis Zhengzhou University Zhengzhou450001 China The National Mobile Communications Research Laboratory Southeast University Nanjing211189 China The Department of Electrical and Computer Engineering Auburn University AuburnAL36949-5201 United States The School of Information Engineering Zhengzhou University Zhengzhou450001 China The Department of Electrical and Computer Engineering The University of Houston HoustonTX77004 United States The Department of Computer Science and Engineering Kyung Hee University Seoul446-701 Korea Republic of

The rapid development of high-speed railways (HSRs) puts forward high requirements on the corresponding communication system. Millimeter wave (mmWave) can be a promising solution due to its wide bandwidth, narrow beams, and rich spectrum resources. However, with the large number of antenna elements employed, energy-efficient solutions at mmWave frequencies are in great demand. Based on a mmWave HSR communication system with multiple mobile relays (MRs) on top of the train, a dynamic power-control scheme for train-ground communications is proposed. The scheme follows the regular movement characteristics of high-speed trains and considers three phases of train movement: the train enters the cell, all MRs are covered in the cell, and the train leaves the cell. The transmit power is further refined according to the number of MRs in the cell and the distance between the train and the remote radio head. By minimizing energy consumption under the constraints of the transmitted data and transmit power budget, the transmit power is allocated to multiple MRs through the multiplier punitive function-based algorithm. Comprehensive simulation results, where the velocity estimation error is taken into account, are provided to demonstrate the effectiveness of the proposed scheme over several baseline schemes. Copyright © 2022, The Authors. All rights reserved.

关键词： Energy efficiency

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