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arXiv 2021年

作者： Chen, Yutong Schönlieb, Carola-Bibiane Liò, Pietro Leiner, Tim Dragotti, Pier Luigi Wang, Ge Rueckert, Daniel Firmin, David Yang, Guang National Heart & Lung Institute Imperial College London LondonSW3 6NP United Kingdom Cardiovascular Research Centre Royal Brompton Hospital LondonSW3 6NP United Kingdom Faculty of Biology University of Cambridge CambridgeCB2 1RX United Kingdom Department of Applied Mathematics and Theoretical Physics University of Cambridge CambridgeCB3 0WA United Kingdom Department of Computer Science and Technology University of Cambridge CambridgeCB3 0FD United Kingdom Utrecht University Medical Centre Utrecht3584 CX Netherlands Department of Electrical and Electronic Engineering Imperial College London LondonSW7 2BU United Kingdom Biomedical Imaging Center Rensselaer Polytechnic Institute TroyNY12180 United States Department of Computing Imperial College London LondonSW7 2BU United Kingdom Institute for Medical Informatics Statistics and Epidemiology Technical University of Munich Munich81675 Germany

Compressed sensing (CS) has been playing a key role in accelerating the magnetic resonance imaging (MRI) acquisition process. With the resurgence of artificial intelligence, deep neural networks and CS algorithms are being integrated to redefine the state of the art of fast MRI. The past several years have witnessed substantial growth in the complexity, diversity, and performance of deep learning-based CS techniques that are dedicated to fast MRI. In this meta-analysis, we systematically review the deep learning-based CS techniques for fast MRI, describe key model designs, highlight breakthroughs, and discuss promising directions. We have also introduced a comprehensive analysis framework and a classification system to assess the pivotal role of deep learning in CS-based acceleration for MRI. © 2021, CC BY-NC-ND.

关键词： Compressed sensing

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Ontology-based automatic reclassification of tissues and organs in histological images 12

Ontology-based automatic reclassification of tissues and org...

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12th Alberto Mendelzon International Workshop on Foundations of Data Management, AMW 2018

作者： Mazo, Claudia Trujillo, Maria Alegre, Enrique Salazar, Liliana Universidad Del Valle Computer and Systems Engineering School Cali Colombia University College Dublin CeADAR: Centre for Applied Data Analytics Research School of Computer Science I-Dublin Ireland OncoMark Limited I-Dublin Ireland Universidad de León Industrial and Informatics Engineering School León Spain Universidad Del Valle Morphology Department Cali Colombia

Heterogeneous data source produces different types of data that cannot be treated in the same way. In this paper, two sources of data are considered: image and human knowledge. The former is rep-resented using visual descriptors and the latter is represented using an ontology. The integration of these data sources is used in the automatic classiffication of tissues and organs of the human cardiovascular system together. Firstly, visual descriptors texture descriptors { are used in the automatic classiffication using a cascade Support Vector Machine. Secondly, obtained classiffication results are refined using a histological ontology of the human cardiovascular system to confirm or reclassified. The final classiffication results are more precise than the obtained using only image data, in all cases. Keywords: Automatic Classiffiation Histological Ontology Histology Images Image Processing. © 2018 CEUR-WS. All rights reserved.

关键词： Ontology

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An Early Stage Researcher's Primer on Systems Medicine Terminology

Network and Systems Medicine

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Network and Systems Medicine 2021年第1期4卷 2-50页

作者： Zanin, Massimiliano Aitya, Nadim A.A. Basilio, José Baumbach, Jan Benis, Arriel Behera, Chandan K. Bucholc, Magda Castiglione, Filippo Chouvarda, Ioanna Comte, Blandine Dao, Tien-Tuan Ding, Xuemei Pujos-Guillot, Estelle Filipovic, Nenad Finn, David P. Glass, David H. Harel, Nissim Iesmantas, Tomas Ivanoska, Ilinka Joshi, Alok Boudjeltia, Karim Zouaoui Kaoui, Badr Kaur, Daman Maguire, Liam P. McClean, Paula L. McCombe, Niamh De Miranda, João Luís Moisescu, Mihnea Alexandru Pappalardo, Francesco Polster, Annikka Prasad, Girijesh Rozman, Damjana Sacala, Ioan Sanchez-Bornot, Jose M. Schmid, Johannes A. Sharp, Trevor Solé-Casals, Jordi Spiwok, Vojtěch Spyrou, George M. Stalidzans, Egils Stres, Blaa Sustersic, Tijana Symeonidis, Ioannis Tieri, Paolo Todd, Stephen Van Steen, Kristel Veneva, Milena Wang, Da-Hui Wang, Haiying Wang, Hui Watterson, Steven Wong-Lin, Kongfatt Yang, Su Zou, Xin Schmidt, Harald H.H.W. Centro de Tecnología Biomédica Universidad Politécnica de Madrid Madrid Spain Intelligent Systems Research Centre School of Computing Engineering and Intelligent Systems Ulster University Ulster United Kingdom Center for Physiology and Pharmacology Institute of Vascular Biology and Thrombosis Research Medical University of Vienna Vienna Austria TUM School of Life Sciences Weihenstephan Technical University of Munich Freising Germany Holon Israel CNR National Research Council IAC Institute for Applied Computing Rome Italy Lab of Computing Medical Informatics and Biomedical Imaging Technologies School of Medicine Aristotle University of Thessaloniki Thessaloniki Greece Université Clermont Auvergne INRAE UNH Plateforme d'Exploration du Métabolisme MetaboHUB Clermont Clermont-Ferrand France Université de Technologie de Compiègne Compiègne France Labex MS2T Control of Technological Systems-of-Systems CNRS and Université de Technologie de Compiègne Compiègne France Faculty of Engineering University of Kragujevac Kragujevac Serbia Kragujevac Serbia Steinbeis Advanced Risk Technologies Institute Doo Kragujevac Kragujevac Serbia Pharmacology and Therapeutics School of Medicine Galway Neuroscience Centre National University of Ireland Galway Ireland School of Computing Ulster University Ulster United Kingdom Holon Israel Department of Mathematics and Natural Sciences Kaunas University of Technology Kaunas Lithuania Faculty of Computer Science and Engineering Ss. Cyril and Methodius University Skopje Macedonia Medicine Faculty Université Libre de Bruxelles CHU de Charleroi Charleroi Belgium Northern Ireland Centre for Stratified Medicine Biomedical Sciences Research Institute Ulster University Ulster United Kingdom Escola Superior de Tecnologia e Gestão Instituto Politécnico de Portalegre Portalegre Portugal Instituto Superior Técnico Universidade de Lisboa Lisboa Portugal Faculty of Automatic Control and Computers University Politehnica of B

Background: Systems Medicine is a novel approach to medicine, that is, an interdisciplinary field that considers the human body as a system, composed of multiple parts and of complex relationships at multiple levels, and further integrated into an environment. Exploring Systems Medicine implies understanding and combining concepts coming from diametral different fields, including medicine, biology, statistics, modeling and simulation, and data science. Such heterogeneity leads to semantic issues, which may slow down implementation and fruitful interaction between these highly diverse fields. Methods: In this review, we collect and explain more than100 terms related to Systems Medicine. These include both modeling and data science terms and basic systems medicine terms, along with some synthetic definitions, examples of applications, and lists of relevant references. Results: This glossary aims at being a first aid kit for the Systems Medicine researcher facing an unfamiliar term, where he/she can get a first understanding of them, and, more importantly, examples and references for digging into the topic. © Massimiliano Zanin et al., 2021;Published by Mary Ann Liebert, Inc. 2021.

关键词： Semantics

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Unobtrusive system for the detection of mental focus depletion 10

Unobtrusive system for the detection of mental focus depleti...

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10th International Conference on e-Health 2018, the 11th International Conference on ICT, Society, and Human Beings 2018 and of the 15th International Conference Web Based Communities and Social Media 2018, part of the Multi Conference on computer Science and Information Systems 2018, MCCSIS 2018

作者： Gialelis, John Pavlou, Panos Panagiotou, Chris Koubias, Stavros Pombo, Nuno Garcia, Nuno Applied Electronics Lab Electrical and Computer Engineering Department University of Patras Patras Greece Instituto de Telecomunicações ALLab Assisted Living Computing and Telecommunications Lab Department of Informatics Universidade da Beira Interior Covilhã Portugal Universidade Lusófona de Humanidades e Tecnologias Lisbon Portugal

ISBN: (纸本)9789898533777

Advances in Wearable Devices and Artificial Intelligence upgrade the use of ICT aiming both at improving humans’ life quality as well as safety. This paper presents a system for the detection of mental focus depletion comprising a robust embedded system used for aggregating EEG data and transferring them in real time to a central server where specific purpose software is used for further processing. The performance of the system is tested using experimental data, as well as its accuracy is depicted against a well-known commercial device. © 2018 MCCSIS 2018 - Multi Conference on computer Science and Information Systems;Proceedings of the International Conferences on e-Health 2018, ICT, Society, and Human Beings 2018 and Web Based Communities and Social Media 2018. All rights reserved.

关键词： Social networking (online)

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The footprint of things: A hybrid approach towards the collection, storage and distribution of life cycle inventory data 5th

The footprint of things: A hybrid approach towards the colle...

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5th International Conference on Information and Communication Technology for Sustainability, ICT4S 2018

作者： Capelleveen, Guido van Pohl, Johanna Fritsch, Andreas Schien, Daniel Department of Industrial Engineering and Business Information Systems University of Twente Netherlands Zentrum Technik und Gesellschaft Technische Universität Berlin Germany Institute of Applied Informatics and Formal Description Methods Karlsruhe Institute of Technology Germany School of Computer Science University of Bristol United Kingdom

Life cycle assessment is a well-established methodology for assessing the environmental impacts of products and services. Unfortunately, an essential part of this life cycle assessment method, collecting inventory data, is extremely time consuming. The quality of manually conducted LCA studies is often limited by uncertainty in the inventory data or narrow scope. Past attempts to overcome these challenges through automation of data collection utilizing the Internet of Things have relied on fully centralized architectures. The drawback of a central repository is the complex coordination between all involved actors in supply chains of products and services. This paper proposes an alternative hybrid approach combining a primary distributed system supplemented with a central repository reducing the need for coordination. This hybrid approach is named "the Footprint of Things". We present a system design that embeds the automatic reporting of life cycle inventory data, such as energy and material flows, into all product components involved in a service delivery. The major strength of our novel system design, among others, is its capacity for real-time and more precise impact calculation of ICT services. © 2018, EasyChair. All rights reserved.

关键词： Life cycle

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Science with the Global Cosmic-ray Observatory (GCOS) 38

Science with the Global Cosmic-ray Observatory (GCOS)

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38th International Cosmic Ray Conference, ICRC 2023

作者： Batista, Rafael Alves Ahlers, M. Alves Batista, R. Assis, P. Battisti, M. Bellido, J.A. Bhatnagar, S. Bismark, K. Bister, T. Bohacova, M. Caccianiga, L. Caruso, R. Carvalho, W. Castellina, A. Colalillo, R. Convenga, F. Dawson, B. De Mitri, I. de Palma, F. Deval, L. di Matteo, A. DuVernois, M. Engel, R. Eser, J. Fitoussi, T. Flaggs, B. Fujii, T. Garzelli, M.V. Gkika, V. Hamal, P. Hariharan, B. Haungs, A. Hnatyk, B. Hörandel, J. Horváth, P. Hrabovsky, M. Huege, T. Ikeda, D. Isar, P.G. James, R. Johnsen, J. Kampert, K.-H. Kleifges, M. Koundal, P. Liu, J. Longo, F. Mandat, D. Mariş, I.C. Matthews, J. Mayotte, E. Medina-Tanco, G. Mulrey, K. Muzio, M.S. Nellen, L. Niechciol, M. Ogio, S. Oikonomou, F. Ostrowski, M. Pont, B. Porcelli, A. Rautenberg, J. Rieger, F. Risse, M. Roth, M. Sako, T. Salamida, F. Santangelo, A. Santos, E. Sarazin, F. Saveliev, A. Schimp, M. Schmidt, D. Schröder, F. Sergijenko, O. Sigl, G. Soldin, D. Spiczak, G. Tameda, Y. Unger, M. van Vliet, A. Vorobiov, S. Wibig, T. Wundheiler, B. Yushkov, A. Zotov, M. Instituto de Física Teórica UAM-CSIC C Nicolás Cabrera 13-15 Madrid28049 Spain Departamento de Física Teórica Universidad Autónoma de Madrid M-15 Madrid28049 Spain Niels Bohr Institute Copenhagen Denmark Instituto de Física Teórica UAM-CSIC Madrid Spain Universidad Autónoma de Madrid Departamento de Física Teórica Madrid Spain Universidade de Lisboa Instituto Superior Técnico Lisboa Portugal Universidade de Lisboa Laboratório de Instrumentação e Física Experimental de Partículas Lisboa Portugal Université de Paris Astroparticule et Cosmologie Paris France The University of Adelaide Physics Department Adelaide Australia Dayalbagh Educational Institute Department of Physics and Computer Science Agra India Institute for Experimental Particle Physics Karlsruhe Germany Radboud University Institute for Mathematics Astrophysics and Particle Physics Nijmegen Netherlands Amsterdam Netherlands Institute of Physics The Czech Academy of Sciences Prague Czech Republic Sezione di Milano Milan Italy Department of Physics and Astronomy "E. Majorana" University of Catania Catania Italy Sezione di Catania Catania Italy Sezione di Torino Turin Italy Turin Italy Università degli Studi di Napoli "Federico II" Naples Italy Sezione di Napoli Naples Italy Università dell’Aquila Dipartimento di Scienze Fisiche e Chimiche L’Aquila Italy Laboratori Nazionali del Gran Sasso L’Aquila Assergi Italy Gran Sasso Science Institute L’Aquila Italy Università del Salento Dipartimento di Matematica e Fisica "E. De Giorgi" Lecce Italy Institute for Astroparticle Physics Karlsruhe Germany University of Wisconsin-Madison Department of Physics MadisonWI United States University of Wisconsin-Madison Wisconsin IceCube Particle Astrophysics Center MadisonWI United States The University of Chicago Department of Astronomy and Astrophysics ChicagoIL United States University of Delaware Bartol Research Institute NewarkDE United States Osaka Metropolitan Univers

The Global Cosmic-ray Observatory (GCOS) is a proposed large-scale observatory for studying ultra-high-energy cosmic particles, including ultra-high-energy cosmic rays (UHECRs), photons, and neutrinos. Its primary goal is to characterise the properties of the highest-energy particles in Nature with unprecedented accuracy, and to identify their elusive sources. With an aperture at least a ten-fold larger than existing observatories, this next-generation facility should start operating after 2030, when present-day detectors will gradually cease their activities. Here we briefly review the scientific case motivating GCOS. We present the status of the project, preliminary ideas for its design, and some estimates of its capabilities. © Copyright owned by the author(s) under the terms of the Creative Commons.

关键词： Cosmic rays

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The Brain Tumor Segmentation (BraTS-METS) Challenge 2023: Brain Metastasis Segmentation on Pre-treatment MRI

arXiv

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arXiv 2023年

作者： Moawad, Ahmed W. Janas, Anastasia Baid, Ujjwal Ramakrishnan, Divya Saluja, Rachit Ashraf, Nader Jekel, Leon Amiruddin, Raisa Adewole, Maruf Albrecht, Jake Anazodo, Udunna Aneja, Sanjay Anwar, Syed Muhammad Bergquist, Timothy Calabrese, Evan Chiang, Veronica Chung, Verena Conte, Gian Marco Marco Dako, Farouk Eddy, James Ezhov, Ivan Familiar, Ariana Farahani, Keyvan Iglesias, Juan Eugenio Jiang, Zhifan Johanson, Elaine Kazerooni, Anahita Fathi Kofler, Florian Krantchev, Kiril LaBella, Dominic Van Leemput, Koen Li, Hongwei Bran Linguraru, Marius George Link, Katherine E. Liu, Xinyang Maleki, Nazanin Meier, Zeke Menze, Bjoern H. Moy, Harrison Osenberg, Klara Piraud, Marie Reitman, Zachary Shinohara, Russel Takeshi Tahon, Nourel hoda Nada, Ayman Velichko, Yuri S. Wang, Chunhao Wiestler, Benedikt Wiggins, Walter Shafique, Umber Willms, Klara Avesta, Arman Bousabarah, Khaled Chakrabarty, Satrajit Gennaro, Nicolo Holler, Wolfgang Kaur, Manpreet LaMontagne, Pamela Lin, MingDe Lost, Jan Marcus, Daniel S. Maresca, Ryan Merkaj, Sarah Nada, Ayaman Pedersen, Gabriel Cassinelli von Reppert, Marc Sotiras, Aristeidis Teytelboym, Oleg Tillmans, Niklas Westerhoff, Malte Youssef, Ayda Godfrey, Devon Floyd, Scott Rauschecker, Andreas Villanueva-Meyer, Javier Pflüger, Irada Cho, Jaeyoung Bendszus, Martin Brugnara, Gianluca Cramer, Justin Perez-Carillo, Gloria Guzman J. Johnson, Derek R. Kam, Anthony Kwan, Benjamin Yin Ming Lai, Lillian Lall, Neil U. Memon, Fatima Patro, Satya Narayana Petrovic, Bojan So, Tiffany Y. Thompson, Gerard Wu, Lei Schrickel, E. Brooke Bansal, Anu Barkhof, Frederik Besada, Cristina Chu, Sammy Druzgal, Jason Dusoi, Alexandru Farage, Luciano Feltrin, Fabricio Fong, Amy Fung, Steve H. Gray, R. Ian Ikuta, Ichiro Iv, Michael Postma, Alida A. Mahajan, Amit Joyner, David Krumpelman, Chase Letourneau-Guillon, Laurent Lincoln, Christie M. Maros, Mate E. Miller, Elka Morón, Fanny Nimchinsky, Esther A. Ozsarlak, Ozkan Patel, Uresh Rohatgi, Saurabh Saha, Atin Sayah, Anousheh Schwartz, Eric D. Shih, Robert Shiroishi, Mark Trinity health Mid Atlantic Hosiptals DarbyPA United States Department of Radiology and Biomedical Imaging Yale School of Medicine New HavenCT United States Division of Computational Pathology Department of Pathology and Laboratory Medicine School of Medicine Indiana University IndianapolisIN United States Department of Electical and Computer Engineering Cornell University Cornell Tech New YorkNY United States Department of Radiology Weill Cornell Medicine New YorkNY United States ImagineQuant Children’s Hospital of Philadelphia PhiladelphiaPA United States College of Medicine Alfaisal University Riyadh Saudi Arabia DKFZ Division of Translational Neurooncology The WTZ German Cancer Consortium DKTK Partner Site University Hospital Essen Essen Germany Medical Artificial Intelligence Lab Crestview Radiology Lagos Nigeria Sage Bionetworks SeattleWA United States Montreal Neurological Institute McGill University Montreal Canada lab Crestview Radiology Lagos Nigeria Department of Therapeutic Radiology Yale School of Medicine New HavenCT United States Sheikh Zayed Institute for Pediatric Surgical Innovation Children’s National Hospital WashingtonDC United States Department of Radiology Mayo Clinic RochesterMN United States Department of Radiology Duke University Medical Center DurhamNC United States Department of Neurosurgery Yale School of Medicine New HavenCT United States Center for Global Health Perelman School of Medicine University of Pennsylvania PA United States Department of Informatics Technical University Munich Germany Children’s Hospital of Philadelphia University of Pennsylvania PhiladelphiaPA United States Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD United States Athinoula A. Martinos Center for Biomedical Imaging Massachusetts General Hospital BostonMA United States Children’s National Hospital WashingtonDC United States PrecisionFDA U.S. Food and Drug Administration S

The translation of AI-generated brain metastases (BM) segmentation into clinical practice relies heavily on diverse, high-quality annotated medical imaging datasets. The BraTS-METS 2023 challenge has gained momentum for testing and benchmarking algorithms using rigorously annotated internationally compiled real-world datasets. This study presents the results of the segmentation challenge and characterizes the challenging cases that impacted the performance of the winning algorithms. Untreated brain metastases on standard anatomic MRI sequences (T1, T2, FLAIR, T1PG) from eight contributed international datasets were annotated in stepwise method: published UNET algorithms, student, neuroradiologist, final approver neuroradiologist. Segmentations were ranked based on lesion-wise Dice and Hausdorff distance (HD95) scores. False positives (FP) and false negatives (FN) were rigorously penalized, receiving a score of 0 for Dice and a fixed penalty of 374 for HD95. The mean scores for the teams were calculated. Eight datasets comprising 1303 studies were annotated, with 402 studies (3076 lesions) released on Synapse as publicly available datasets to challenge competitors. Additionally, 31 studies (139 lesions) were held out for validation, and 59 studies (218 lesions) were used for testing. Segmentation accuracy was measured as rank across subjects, with the winning team achieving a LesionWise mean score of 7.9. The Dice score for the winning team was 0.65 ± 0.25. Common errors among the leading teams included false negatives for small lesions and misregistration of masks in space. The Dice scores and lesion detection rates of all algorithms diminished with decreasing tumor size, particularly for tumors smaller than 100 mm3. In conclusion, algorithms for BM segmentation require further refinement to balance high sensitivity in lesion detection with the minimization of false positives and negatives. The BraTS-METS 2023 challenge successfully curated well-annotated, diverse d

关键词： Image segmentation

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Augmentation of wastewater-based epidemiology with machine learning to support global health surveillance

Nature Water

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Nature Water 2025年 1-11页

作者： Eva Aßmann Christopher Irrgang Hugues Richard Martin Hölzer Timo Greiner Alexander Ullrich Matthew Wade Shelesh Agrawal Susanne Lackner Fabian Amman Sindy Böttcher Markus Landthaler Emanuel Wyler Serghei Mangul Viorel Munteanu Fotis Psomopoulos Maureen Smith Maria Trofimova Max von Kleist Centre for Artificial Intelligence in Public Health Research (ZKI-PH) Robert Koch Institute Berlin Germany Genome Competence Center (MF1) Robert Koch Institute Berlin Germany Department of Infectious Disease Epidemiology Robert Koch Institute Berlin Germany Chief Data Officer Group UK Health Security Agency London UK Chair of Water and Environmental Biotechnology Institute IWAR Department of Civil and Environmental Engineering Sciences Technical University of Darmstadt Darmstadt Germany CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Vienna Austria Institute for Hygiene and Applied Immunology Medical University of Vienna Vienna Austria Gastroenteritis and Hepatitis Pathogens and Enteroviruses (FG15) Robert Koch Institute Berlin Germany Berlin Institute for Medical Systems Biology Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC) Berlin Germany Institute for Biology Humboldt-Universität zu Berlin Berlin Germany Titus Family Department of Clinical Pharmacy USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences University of Southern California Los Angeles CA USA Department of Biological and Morphofunctional Sciences College of Medicine and Biological Sciences Stefan cel Mare University of Suceava Suceava Romania Department of Computers Informatics and Microelectronics Technical University of Moldova Chisinau Moldova Institute of Applied Biosciences Center for Research and Technology Hellas Thessaloniki Greece Systems Medicine of Infectious Disease (P5) Robert Koch Institute Berlin Germany Department of Mathematics and Computer Science Freie Universität Berlin Berlin Germany

Wastewater-based epidemiology (WBE) has proven to be a valuable tool for monitoring the evolution and spread of global health threats, from pathogens to antimicrobial resistances. Throughout the COVID-19 pandemic, multiple wastewater surveillance programmes have advanced statistical and machine learning methods for detecting pathogens from wastewater sequencing data and correlating measured targets with the represented population to infer meaningful conclusions for public health. Integrating contextual data can account for measurement uncertainties across the WBE workflow that affect the reliability of analyses. However, the broader availability and harmonization of data are major obstacles to method development. Here we review the benefits and limitations of wastewater-related data streams, highlighting the potential of machine learning to leverage these streams for normalization and other WBE applications. We emphasize the relevance of developing global frameworks for integrating WBE with other health surveillance systems and discuss next steps to address current and foreseeable challenges for robust and interpretable machine learning-enhanced WBE.

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Emulating the impact of additional proton–proton interactions in the ATLAS simulation by presampling sets of inelastic Monte Carlo events

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Computing and Software for Big Science 2022年第1期6卷 1-35页

作者： Aad, G. Abbott, B. Abbott, D.C. Abud, A. Abed Abeling, K. Abhayasinghe, D.K. Abidi, S.H. AbouZeid, O.S. Abraham, N.L. Abramowicz, H. Abreu, H. Abulaiti, Y. Hoffman, A. C. Abusleme Acharya, B.S. Achkar, B. Adam, L. Bourdarios, C. Adam Adamczyk, L. Adamek, L. Adelman, J. Adiguzel, A. Adorni, S. Adye, T. Affolder, A.A. Afik, Y. Agapopoulou, C. Agaras, M.N. Aggarwal, A. Agheorghiesei, C. Aguilar-Saavedra, J.A. Ahmad, A. Ahmadov, F. Ahmed, W.S. Ai, X. Aielli, G. Akatsuka, S. Akbiyik, M. Åkesson, T.P.A. Akilli, E. Akimov, A.V. Khoury, K. Al Alberghi, G.L. Albert, J. Verzini, M. J. Alconada Alderweireldt, S. Aleksa, M. Aleksandrov, I.N. Alexa, C. Alexopoulos, T. Alfonsi, A. Alfonsi, F. Alhroob, M. Ali, B. Ali, S. Aliev, M. Alimonti, G. Allaire, C. Allbrooke, B.M.M. Allport, P.P. Aloisio, A. Alonso, F. Alpigiani, C. Camelia, E. Alunno Estevez, M. Alvarez Alviggi, M.G. Coutinho, Y. Amaral Ambler, A. Ambroz, L. Amelung, C. Amidei, D. Santos, S. P. Amor Dos Amoroso, S. Amrouche, C.S. Anastopoulos, C. Andari, N. Andeen, T. Anders, J.K. Andrean, S.Y. Andreazza, A. Andrei, V. Anelli, C.R. Angelidakis, S. Angerami, A. Anisenkov, A.V. Annovi, A. Antel, C. Anthony, M.T. Antipov, E. Antonelli, M. Antrim, D.J.A. Anulli, F. Aoki, M. Pozo, J. A. Aparisi Aparo, M.A. Bella, L. Aperio Aranzabal, N. Ferraz, V. Araujo Arcangeletti, C. Arce, A.T.H. Arguin, J.-F. Argyropoulos, S. Arling, J.-H. Armbruster, A.J. Armstrong, A. Arnaez, O. Arnold, H. Tame, Z. P. Arrubarrena Artoni, G. Asada, H. Asai, K. Asai, S. Asbah, N.A. Asimakopoulou, E.M. Asquith, L. Assahsah, J. Assamagan, K. Astalos, R. Atkin, R.J. Atkinson, M. Atlay, N.B. Atmani, H. Atmasiddha, P.A. Augsten, K. Austrup, V.A. Avolio, G. Ayoub, M.K. Azuelos, G. Babal, D. Bachacou, H. Bachas, K. Backman, F. Bagnaia, P. Bahrasemani, H. Bailey, A.J. Bailey, V.R. Baines, J.T. Bakalis, C. Baker, O.K. Bakker, P.J. Bakos, E. Gupta, D. Bakshi Balaji, S. Balasubramanian, R. Baldin, E.M. Balek, P. Balli, F. Balunas, W.K. Balz, J. Banas, E. Bandieramonte, M. Bandyopadhyay, A. Barak, L. Barbe, W.M. Ba Department of Physics University of Adelaide Adelaide Australia Physics Department SUNY Albany Albany NY United States Department of Physics University of Alberta Edmonton AB Canada Department of Physics Ankara University Ankara Turkey Istanbul Aydin University Application and Research Center for Advanced Studies Istanbul Turkey Division of Physics TOBB University of Economics and Technology Ankara Turkey LAPP Univ. Savoie Mont Blanc CNRS/IN2P3 Annecy France High Energy Physics Division Argonne National Laboratory Argonne IL United States Department of Physics University of Arizona Tucson AZ United States Department of Physics University of Texas at Arlington Arlington TX United States Physics Department National and Kapodistrian University of Athens Athens Greece Physics Department National Technical University of Athens Zografou Greece Department of Physics University of Texas at Austin Austin TX United States Bahcesehir University Faculty of Engineering and Natural Sciences Istanbul Turkey Istanbul Bilgi University Faculty of Engineering and Natural Sciences Istanbul Turkey Department of Physics Bogazici University Istanbul Turkey Department of Physics Engineering Gaziantep University Gaziantep Turkey Institute of Physics Azerbaijan Academy of Sciences Baku Azerbaijan Institut de Física d’Altes Energies (IFAE) Barcelona Institute of Science and Technology Barcelona Spain Institute of High Energy Physics Chinese Academy of Sciences Beijing China Physics Department Tsinghua University Beijing China Department of Physics Nanjing University Nanjing China University of Chinese Academy of Science (UCAS) Beijing China Institute of Physics University of Belgrade Belgrade Serbia Department for Physics and Technology University of Bergen Bergen Norway Physics Division Lawrence Berkeley National Laboratory and University of California Berkeley CA United States Institut für Physik Humboldt Universität zu Berlin Berlin Germany Albert Ei

The accurate simulation of additional interactions at the ATLAS experiment for the analysis of proton–proton collisions delivered by the Large Hadron Collider presents a significant challenge to the computing resources. During the LHC Run 2 (2015–2018), there were up to 70 inelastic interactions per bunch crossing, which need to be accounted for in Monte Carlo (MC) production. In this document, a new method to account for these additional interactions in the simulation chain is described. Instead of sampling the inelastic interactions and adding their energy deposits to a hard-scatter interaction one-by-one, the inelastic interactions are presampled, independent of the hard scatter, and stored as combined events. Consequently, for each hard-scatter interaction, only one such presampled event needs to be added as part of the simulation chain. For the Run 2 simulation chain, with an average of 35 interactions per bunch crossing, this new method provides a substantial reduction in MC production CPU needs of around 20%, while reproducing the properties of the reconstructed quantities relevant for physics analyses with good accuracy. © 2022, The Author(s).

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The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)

arXiv

引用

arXiv 2023年

作者： Kazerooni, Anahita Fathi Khalili, Nastaran Liu, Xinyang Haldar, Debanjan Jiang, Zhifan Anwar, Syed Muhammed Albrecht, Jake Adewole, Maruf Anazodo, Udunna Anderson, Hannah Bagheri, Sina Baid, Ujjwal Bergquist, Timothy Borja, Austin J. Calabrese, Evan Chung, Verena Conte, Gian-Marco Dako, Farouk Eddy, James Ezhov, Ivan Familiar, Ariana Farahani, Keyvan Haldar, Shuvanjan Iglesias, Juan Eugenio Janas, Anastasia Johansen, Elaine Jones, Blaise V. Kofler, Florian LaBella, Dominic Lai, Hollie Anne Van Leemput, Koen Li, Hongwei Bran Maleki, Nazanin McAllister, Aaron S. Meier, Zeke Menze, Bjoern Moawad, Ahmed W. Nandolia, Khanak K. Pavaine, Julija Piraud, Marie Poussaint, Tina Prabhu, Sanjay P. Reitman, Zachary Rodriguez, Andres Rudie, Jeffrey D. Sanchez-Montano, Mariana Shaikh, Ibraheem Salman Shah, Lubdha M. Sheth, Nakul Shinohara, Russel Taki Tu, Wenxin Viswanathan, Karthik Wang, Chunhao Ware, Jeffrey B. Wiestler, Benedikt Wiggins, Walter Zapaishchykova, Anna Aboian, Mariam Bornhorst, Miriam de Blank, Peter Deutsch, Michelle Fouladi, Maryam Hoffman, Lindsey Kann, Benjamin Lazow, Margot Mikael, Leonie Nabavizadeh, Ali Packer, Roger Resnick, Adam Rood, Brian Vossough, Arastoo Bakas, Spyridon Linguraru, Marius George Children’s Hospital of Philadelphia PhiladelphiaPA United States Department of Neurosurgery University of Pennsylvania PhiladelphiaPA United States University of Pennsylvania PhiladelphiaPA United States Sheikh Zayed Institute for Pediatric Surgical Innovation Children’s National Hospital WashingtonDC United States Department of Neurosurgery Thomas Jefferson University Hospital PA United States Sage Bionetworks United States Lab Crestview Radiology Lagos Nigeria McGill University MontrealQC Canada Department of Radiology Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Pathology and Laboratory Medicine Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Neurosurgery The University of Southern California CA United States Department of Radiology Duke University Medical Center United States Mayo Clinic MN United States Center for Global Health Perelman School of Medicine University of Pennsylvania PhiladelphiaPA United States Department of Informatics Technical University Munich Germany TranslaTUM - Central Institute for Translational Cancer Research Technical University of Munich Germany Cancer Imaging Program National Cancer Institute National Institutes of Health BethesdaMD United States Biomedical Engineering Rutgers University New BrunswickNJ United States Athinoula A Martinos Center for Biomedical Imaging Massachusetts General Hospital BostonMA United States Yale University New HavenCT United States PrecisionFDA U.S. Food and Drug Administration Silver SpringMD United States Cincinnati Children’s Hospital Medical Center United States Helmholtz AI Helmholtz Munich Germany Department of Radiation Oncology Duke University Medical Center United States Department of Radiology Children’s Health Orange County CA United States Department of Applied Mathematics and Computer Science Technical University of Denmark Denmark Department of Radiol

Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. The MICCAI Brain Tumor Segmentation (BraTS) Challenge is a landmark community benchmark event with a successful history of 12 years of resource creation for the segmentation and analysis of adult glioma. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge, which represents the first BraTS challenge focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The BraTS-PEDs 2023 challenge focuses on benchmarking the development of volumentric segmentation algorithms for pediatric brain glioma through standardized quantitative performance evaluation metrics utilized across the BraTS 2023 cluster of challenges. Models gaining knowledge from the BraTS-PEDs multi-parametric structural MRI (mpMRI) training data will be evaluated on separate validation and unseen test mpMRI dataof high-grade pediatric glioma. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors. © 2023, CC BY.

关键词： Tumors

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