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Interactive color mosaic and dendrogram displays for signal/noise optimization in microarray data analysis

Interactive color mosaic and dendrogram displays for signal/...

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IEEE International Conference on Multimedia and Expo (ICME)

作者： Jinwook Seo M. Bakay Po Zhao Yi-Wen Chen P. Clarkson B. Shneiderman E.P. Hoffman Research Center for Genetic Medicine Children''s Hospital National Medical Center USA Department of Computer Science & Human-Computer Interaction Laboratory University of Maryland USA Exercise Science University of Massachusetts Amherst USA

Data analysis and visualization is strongly influenced by noise and noise filters. There are multiple sources of "noise" in microarray data analysis, but signal/noise ratios are rarely optimized, or even considered. Here, we report a noise analysis of a novel 13 million oligonucleotide dataset - 25 human U133A (/spl sim/500,000 features) profiles of patient muscle biopsies. We use our recently described interactive visualization tool, the hierarchical clustering explorer (HCE) to systemically address the effect of different noise filters on resolution of arrays into "correct" biological groups (unsupervised clustering into three patient groups of known diagnosis). We varied probe set interpretation methods (MAS 5.0, RMA), "present call" filters, and clustering linkage methods, and investigated the results in HCE. HCE's interactive features enabled us to quickly see the impact of these three variables. Dendrogram displays showed the clustering results systematically, and color mosaic displays provided a visual support for the results. We show that each of these three variables has a strong effect on unsupervised clustering. For this dataset, the strength of the biological variable was maximized, and noise minimized, using MAS 5.0, 10% present call filter, and average group linkage. We propose a general method of using interactive tools to identify the optimal signal/noise balance or the optimal combination of these three variables to maximize the effect of the desired biological variable on data interpretation.

关键词： Colored noise Color Displays Data analysis Filters Data visualization Signal to noise ratio Couplings humans Muscles

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The design of a search agent that manages information for naive users

The design of a search agent that manages information for na...

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International Conference on Professional Communication (IPCC)

作者： M. Chatterjee S. Adali Human-Compu fer Interaction Rensselaer Polytechnic Institute USA Department of Computer Science Rensselaer Polytechnic Institute USA

A software agent is being built to help naive users effectively perform the search tasks without feeling intimidated or overwhelmed by the technology or the tool. The display of information as well as the content of it can either be too much (the problem of precision) or too little (the recall problem) which in turn can leave a naive user feel frustrated with the search. This agent's aim is to assist these users with their search goals. The overall strategy is to understand the search goal and then "push" and "pull" information to match the needs.

关键词： Information management Cities and towns computer science Educational institutions System testing Software agents Information systems Prototypes Technology management computer displays

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A pair-wise decision fusion framework: recognition of human faces

A pair-wise decision fusion framework: recognition of human ...

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International Conference on Information Fusion

作者： H. Alam F. Rahman Y. Tarnikova R. Hartono Human Computer Interaction BCL Technologies Inc. Santa Clara CA USA Computer Science Department Santa Clara University Santa Clara CA USA

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Recent methods for image-based modeling and rendering

Recent methods for image-based modeling and rendering

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IEEE Annual International Symposium Virtual Reality

作者： D. Burschka G.D. Hager Z. Dodds M. Jagersand D. Cobzas K. Yerex Computational Interaction and Robotics Laboratory Johns Hopkins University USA Department of Computer Science Johns Hopkins University USA Department of Computer Science Harvey Mudd College USA Department of Computer Science University of Alberta Canada Virtual Universe Corporation Canada

A long-standing goal in image-based modeling and rendering is to capture a scene from camera images and construct a sufficient model to allow photo-realistic rendering of new views. With the confluence of computer graphics and vision, the combination of research on recovering geometric structure from un-calibrated cameras with modeling and rendering has yielded numerous new methods. Yet, many challenging issues remain to be addressed before a sufficiently general and robust system could be built to (for instance) allow an average user to model their home and garden from camcorder video. This tutorial aims to give researchers and students in computer graphics a working knowledge of relevant theory and techniques covering the steps from real-time vision for tracking and the capture of scene geometry and appearance, to the efficient representation and real-time rendering of image-based models. It also includes hands-on demos of real-time visual tracking, modeling and rendering systems.

关键词： Rendering (computer graphics) computer science Layout Cameras computer graphics Solid modeling Computational geometry Real time systems Hardware Robots

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human motion-based environment complexity measures for robotics

Human motion-based environment complexity measures for robot...

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IEEE International Workshop on Intelligent Robots and Systems (IROS)

作者： D.A. Shell M.J. Mataric Interaction Laboratory Center for Robotics and Embedded Systems Department of Computer Science University of Southern California Los Angeles CA USA

This paper describes how environmental complexity measures can be employed in the process of validating experimental robotics work. We advocate the use of metrics that attempt to quantify the 'difficulty' of motion for a given environment. Space syntax methods (from the urban and building design literature) and fluid-flow models (used in crowd modeling) are described and proposed as relevant measures for mobile robotics domains. We show experimentally that these two metrics give very different expressions of complexity. We then discuss how, given their properties, these different metrics may be applied to robotics controller design and evaluation.

关键词： humans Orbital robotics Motion measurement Mobile robots Robot sensing systems Time measurement Extraterrestrial measurements Robot vision systems Embedded system computer science

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Individual differences in program comprehension strategies in unfamiliar programming systems

Individual differences in program comprehension strategies i...

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IEEE Workshop on Program Comprehension

作者： A.J. Ko B. Uttl Human-Computer Interaction Institute School of Computer Science Carnegie Mellon University Pittsburgh PA USA Department of Psychology College of Liberal Arts Oregon State University Corvallis OR USA

This study examines the effect of individual differences on the program comprehension strategies of users working with an unfamiliar programming system. Participants of varying programming expertise were given a battery of psychological tests, a brief introduction to a statistical programming environment, and a 20-minute debugging task. Our data show three distinct comprehension strategies that were related to programming experience, but individuals with stronger domain knowledge for specific bugs tended to succeed.

关键词： Programming profession Debugging Psychology computer bugs Predictive models Documentation computer science Educational institutions Art Batteries

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Applying usability engineering methodology to building a search agent for Web applications

Applying usability engineering methodology to building a sea...

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International Conference on Professional Communication (IPCC)

作者： M. Chatterjee R.A. Grice S. Adali Human-Computer Interaction Rensselaer Polytechnic Institute USA Department of Language Literature and Communication and Faculty for Information Technology Rensselaer Polytechnic Institute USA Department of Computer Science Rensselaer Polytechnic Institute USA

Search agents can improve users' perceptions of how effective and efficient database retrieval is. In connection with an on-going project for community interaction, a search agent was designed with a strong theore... 详细信息

关键词： Usability Application software Particle measurements ISO User centered design Information technology computer science Databases Information retrieval Testing

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Flexible self-organizing maps by information maximization

Flexible self-organizing maps by information maximization

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International Joint Conference on Neural Networks (IJCNN)

作者： R. Kamimura T. Takeuchi Information Science Laboratory and Future Science and Technology Joint Research Center Tokai University Hiratsuka Kanagawa Japan Human-Computer Interaction Group Institute for Human Science and Biomedical Engineering National Institute for Advanced Industrial Science and Technology Tsukuba Japan

In this paper, we propose a new information theoretic method for self-organizing maps. The method aims to control competitive processes flexibly, that is, to produce different competitive unit activations according to information content obtained in learning. Competition is realized by maximizing mutual information between input patterns and competitive units. Competitive unit outputs are computed by the inverse of distance between input patterns and competitive unit. As distance is smaller, a neuron tends to fire strongly. Thus, winning neurons represent faithfully input patterns. We applied our method to a road classification problem. Experimental results confirmed that the new method could produce more explicit self-organizing maps than conventional self-organizing methods.

关键词： Self organizing feature maps Neurons Mutual information Entropy Neural networks Information science humans Biomedical engineering Process control Fires

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Mood and task coordination of home robots

Mood and task coordination of home robots

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IEEE International Conference on Robotics and Automation (ICRA)

作者： Myung-Jin Jung F. Arai Y. Hasegawa T. Fukuda Human Computer Interaction Laboratory Samsung Advanced Institute of Technology Yongin si Gyeonggi South Korea Department of Micro System Engineering University of Nagoya Nagoya Japan

Many entertainment and healing robots have been developed. These robots have synthetic emotions so that they select behavior based on their current emotional state. On the contrary conventional robots which have designed to perform repetitive factor or office jobs do not have such emotions. Usually human operators assign tasks in explicit manner using keyboard or voice commands. In this paper we propose a coordination mechanism between robot mood (an activated emotion) and its task. On one hand, referring to the emotion-task history of the mechanism, the robot selects a task depending on its current mood if there is no explicit task command from the user. On the other hand, when it performs a task, a particular emotion gets boosted based on the same emotion-task history so that this emotion is more likely to be activated by external stimuli.

关键词： Mood Robot kinematics Intelligent robots History Robot sensing systems Systems engineering and theory human robot interaction Production facilities Intelligent sensors Intelligent agent

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Mutual disambiguation of 3D multimodal interaction in augmented and virtual reality

Mutual disambiguation of 3D multimodal interaction in augmen...

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ICMI'03: Fifth International Conference on Multimodal Interfaces

作者： Kaiser, Ed Olwal, Alex McGee, David Benko, Hrvoje Corradini, Andrea Li, Xiaoguang Cohen, Phil Feiner, Steven Oregon Health and Science University OGI School of Science and Eng. 20000 NW Walker Road Beaverton OR 97006 United States Columbia University Department of Computer Science 1214 Amsterdam Avenue New York NY 10027 United States Pacific Northwest National Laboratory Rich Interaction Environments 906 Battelle Boulevard Richland WA 99352 United States

ISBN: (纸本)1581136218

We describe an approach to 3D multimodal interaction in immersive augmented and virtual reality environments that accounts for the uncertain nature of the information sources. The resulting multimodal system fuses symbolic and statistical information from a set of 3D gesture, spoken language, and referential agents. The referential agents employ visible or invisible volumes that can be attached to 3D trackers in the environment, and which use a time-stamped history of the objects that intersect them to derive statistics for ranking potential referents. We discuss the means by which the system supports mutual disambiguation of these modalities and information sources, and show through a user study how mutual disambiguation accounts for over 45% of the successful 3D multimodal interpretations. An accompanying video demonstrates the system in action. Copyright 2003 ACM.

关键词： Virtual reality

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