The zero-watermarking methods provide a means of lossless, which was adopted to protect medical image copyright requiring high integrity. However, most existing studies have only focused on robustness and there has be...
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Predicting RNA binding protein(RBP) binding sites on circular RNAs(circ RNAs) is a fundamental step to understand their interaction mechanism. Numerous computational methods are developed to solve this problem, but th...
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Predicting RNA binding protein(RBP) binding sites on circular RNAs(circ RNAs) is a fundamental step to understand their interaction mechanism. Numerous computational methods are developed to solve this problem, but they cannot fully learn the features. Therefore, we propose circ-CNNED, a convolutional neural network(CNN)-based encoding and decoding framework. We first adopt two encoding methods to obtain two original matrices. We preprocess them using CNN before fusion. To capture the feature dependencies, we utilize temporal convolutional network(TCN) and CNN to construct encoding and decoding blocks, respectively. Then we introduce global expectation pooling to learn latent information and enhance the robustness of circ-CNNED. We perform circ-CNNED across 37 datasets to evaluate its effect. The comparison and ablation experiments demonstrate that our method is superior. In addition, motif enrichment analysis on four datasets helps us to explore the reason for performance improvement of circ-CNNED.
Images obtained from hyperspectral sensors provide information about the target area that extends beyond the visible portions of the electromagnetic ***,due to sensor limitations and imperfections during the image acq...
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Images obtained from hyperspectral sensors provide information about the target area that extends beyond the visible portions of the electromagnetic ***,due to sensor limitations and imperfections during the image acquisition and transmission phases,noise is introduced into the acquired image,which can have a negative impact on downstream analyses such as classification,target tracking,and spectral *** in hyperspectral images(HSI)is modelled as a combination from several sources,including Gaussian/impulse noise,stripes,and *** HSI restoration method for such a mixed noise model is ***,a joint optimisation framework is proposed for recovering hyperspectral data corrupted by mixed Gaussian-impulse noise by estimating both the clean data as well as the sparse/impulse noise ***,a hyper-Laplacian prior is used along both the spatial and spectral dimensions to express sparsity in clean image ***,to model the sparse nature of impulse noise,anℓ_(1)−norm over the impulse noise gradient is *** the proposed methodology employs two distinct priors,the authors refer to it as the hyperspectral dual prior(HySpDualP)*** the best of authors'knowledge,this joint optimisation framework is the first attempt in this *** handle the non-smooth and nonconvex nature of the generalℓ_(p)−norm-based regularisation term,a generalised shrinkage/thresholding(GST)solver is ***,an efficient split-Bregman approach is used to solve the resulting optimisation *** results on synthetic data and real HSI datacube obtained from hyperspectral sensors demonstrate that the authors’proposed model outperforms state-of-the-art methods,both visually and in terms of various image quality assessment metrics.
Industrial cyber-physical systems closely integrate physical processes with cyberspace, enabling real-time exchange of various information about system dynamics, sensor outputs, and control decisions. The connection b...
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Industrial cyber-physical systems closely integrate physical processes with cyberspace, enabling real-time exchange of various information about system dynamics, sensor outputs, and control decisions. The connection between cyberspace and physical processes results in the exposure of industrial production information to unprecedented security risks. It is imperative to develop suitable strategies to ensure cyber security while meeting basic performance *** the perspective of control engineering, this review presents the most up-to-date results for privacy-preserving filtering,control, and optimization in industrial cyber-physical systems. Fashionable privacy-preserving strategies and mainstream evaluation metrics are first presented in a systematic manner for performance evaluation and engineering *** discussion discloses the impact of typical filtering algorithms on filtering performance, specifically for privacy-preserving Kalman filtering. Then, the latest development of industrial control is systematically investigated from consensus control of multi-agent systems, platoon control of autonomous vehicles as well as hierarchical control of power systems. The focus thereafter is on the latest privacy-preserving optimization algorithms in the framework of consensus and their applications in distributed economic dispatch issues and energy management of networked power systems. In the end, several topics for potential future research are highlighted.
Blockchain technology has garnered significant attention from global organizations and researchers due to its potential as a solution for centralized system ***,the Internet of Things(IoT)has revolutionized the Fourth...
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Blockchain technology has garnered significant attention from global organizations and researchers due to its potential as a solution for centralized system ***,the Internet of Things(IoT)has revolutionized the Fourth Industrial Revolution by enabling interconnected devices to offer innovative services,ultimately enhancing human *** paper presents a new approach utilizing lightweight blockchain technology,effectively reducing the computational burden typically associated with conventional blockchain *** integrating this lightweight blockchain with IoT systems,substantial reductions in implementation time and computational complexity can be ***,the paper proposes the utilization of the Okamoto Uchiyama encryption algorithm,renowned for its homomorphic characteristics,to reinforce the privacy and security of IoT-generated *** integration of homomorphic encryption and blockchain technology establishes a secure and decentralized platformfor storing and analyzing sensitive data of the supply chain *** platformfacilitates the development of some business models and empowers decentralized applications to perform computations on encrypted data while maintaining data *** results validate the robust security of the proposed system,comparable to standard blockchain implementations,leveraging the distinctive homomorphic attributes of the Okamoto Uchiyama algorithm and the lightweight blockchain paradigm.
In the wake of rapid advancements in artificial intelligence(AI), we stand on the brink of a transformative leap in data systems. The imminent fusion of AI and DB(AI×DB) promises a new generation of data systems,...
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In the wake of rapid advancements in artificial intelligence(AI), we stand on the brink of a transformative leap in data systems. The imminent fusion of AI and DB(AI×DB) promises a new generation of data systems, which will relieve the burden on end-users across all industry sectors by featuring AI-enhanced functionalities, such as personalized and automated in-database AI-powered analytics, and selfdriving capabilities for improved system performance. In this paper, we explore the evolution of data systems with a focus on deepening the fusion of AI and DB. We present NeurDB, an AI-powered autonomous data system designed to fully embrace AI design in each major system component and provide in-database AI-powered analytics. We outline the conceptual and architectural overview of NeurDB, discuss its design choices and key components, and report its current development and future plan.
Therapeutic peptides contribute significantly to human health and have the potential for personalized medicine. The prediction for the therapeutic peptides is beneficial and emerging for the discovery of drugs. Althou...
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Therapeutic peptides contribute significantly to human health and have the potential for personalized medicine. The prediction for the therapeutic peptides is beneficial and emerging for the discovery of drugs. Although several computational approaches have emerged to discern the functions of therapeutic peptides, predicting multi-functional therapeutic peptide types is challenging. In this research, a novel approach termed TPpred-SC has been introduced. This method leverages a pretrained protein language model alongside multi-label supervised contrastive learning to predict multi-functional therapeutic *** framework incorporates sequential semantic information directly from large-scale protein sequences in TAPE. Then, TPpred-SC exploits multi-label supervised contrastive learning to enhance the representation of peptide sequences for imbalanced multi-label therapeutic peptide prediction. The experimental findings demonstrate that TPpred-SC achieves superior performance compared to existing related methods. To serve our work more efficiently, the web server of TPpred-SC can be accessed at http://***/TPpred-SC.
Cross-platform binary code similarity detection aims at detecting whether two or more pieces of binary code are similar or not. Existing approaches that combine control flow graphs(CFGs)-based function representation ...
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Cross-platform binary code similarity detection aims at detecting whether two or more pieces of binary code are similar or not. Existing approaches that combine control flow graphs(CFGs)-based function representation and graph convolutional network(GCN)-based similarity analysis are the best-performing ones. Due to a large amount of convolutional computation and the loss of structural information, the use of convolution networks will inevitably bring problems such as high overhead and sometimes inaccuracy. To address these issues, we propose a fast cross-platform binary code similarity detection framework that takes advantage of natural language processing(NLP)and inductive graph neural network(GNN) for basic blocks embedding and function representation respectively by simulating extracting structural features and temporal features. GNN's node-centric and small batch is a suitable training way for large CFGs, it can greatly reduce computational overhead. Various NLP basic block embedding models and GNNs are evaluated. Experimental results show that the scheme with long short term memory(LSTM)for basic blocks embedding and inductive learning-based Graph SAGE(GAE) for function representation outperforms the state-of-the-art works. In our framework, we can take only 45% overhead. Improve efficiency significantly with a small performance trade-off.
The oropharyngeal swabbing is a pre-diagnostic procedure used to test various respiratory diseases, including COVID and Influenza A (H1N1). To improve the testing efficiency of testing, a real-time, accurate, and robu...
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The oropharyngeal swabbing is a pre-diagnostic procedure used to test various respiratory diseases, including COVID and Influenza A (H1N1). To improve the testing efficiency of testing, a real-time, accurate, and robust sampling point localization algorithm is needed for robots. However, current solutions rely heavily on visual input, which is not reliable enough for large-scale deployment. The transformer has significantly improved the performance of image-related tasks and challenged the dominance of traditional convolutional neural networks (CNNs) in the image field. Inspired by its success, we propose a novel self-aligning multi-modal transformer (SAMMT) to dynamically attend to different parts of unaligned feature maps, preventing information loss caused by perspective disparity and simplifying overall implementation. Unlike preexisting multi-modal transformers, our attention mechanism works in image space instead of embedding space, rendering the need for the sensor registration process obsolete. To facilitate the multi-modal task, we collected and annotate an oropharynx localization/segmentation dataset by trained medical personnel. This dataset is open-sourced and can be used for future multi-modal research. Our experiments show that our model improves the performance of the localization task by 4.2% compared to the pure visual model, and reduces the pixel-wise error rate of the segmentation task by 16.7% compared to the CNN baseline.
Offline reinforcement learning(RL) has gathered increasing attention in recent years, which seeks to learn policies from static datasets without active online exploration. However, the existing offline RL approaches o...
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Offline reinforcement learning(RL) has gathered increasing attention in recent years, which seeks to learn policies from static datasets without active online exploration. However, the existing offline RL approaches often require a large amount of pre-collected data and hence are hardly implemented by a single agent in practice. Inspired by the advancement of federated learning(FL), this paper studies federated offline reinforcement learning(FORL),whereby multiple agents collaboratively carry out offline policy learning with no need to share their raw ***, a straightforward solution is to simply retrofit the off-the-shelf offline RL methods for FL, whereas such an approach easily overfits individual datasets during local updating, leading to instability and subpar performance. To overcome this challenge, we propose a new FORL algorithm, named model-free(MF)-FORL, that exploits novel“proximal local policy evaluation” to judiciously push up action values beyond local data support, enabling agents to capture the individual information without forgetting the aggregated knowledge. Further, we introduce a model-based variant, MB-FORL, capable of improving the generalization ability and computational efficiency via utilizing a learned dynamics model. We evaluate the proposed algorithms on a suite of complex and high-dimensional offline RL benchmarks, and the results demonstrate significant performance gains over the baselines.
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