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Automated Ensemble Multimodal Machine Learning for Healthcare

IEEE Journal of Biomedical and Health Informatics 2025年第6期29卷 4213-4226页

作者： Imrie, Fergus Denner, Stefan Brunschwig, Lucas S. Maier-Hein, Klaus Van Der Schaar, Mihaela University of Oxford Department of Statistics Oxford United Kingdom Heidelberg University Faculty of Mathematics and Computer Science Germany École Polytechnique Fédérale de Lausanne Switzerland Division of Medical Image Computing Germany Heidelberg University Hospital Pattern Analysis and Learning Group Department of Radiation Oncology Germany Heidelberg Germany University of Cambridge Department of Applied Mathematics and Theoretical Physics United Kingdom

The application of machine learning in medicine and healthcare has led to the creation of numerous diagnostic and prognostic models. However, despite their success, current approaches generally issue predictions using data from a single modality. This stands in stark contrast with clinician decision-making which employs diverse information from multiple sources. While several multimodal machine learning approaches exist, significant challenges in developing multimodal systems remain that are hindering clinical adoption. In this paper, we introduce a multimodal framework, AutoPrognosis-M, that enables the integration of structured clinical (tabular) data and medical imaging using automated machine learning. AutoPrognosis-M incorporates 17 imaging models, including convolutional neural networks and vision transformers, and three distinct multimodal fusion strategies. In an illustrative application using a multimodal skin lesion dataset, we highlight the importance of multimodal machine learning and the power of combining multiple fusion strategies using ensemble learning. We have open-sourced our framework as a tool for the community and hope it will accelerate the uptake of multimodal machine learning in healthcare and spur further innovation. © 2013 IEEE.

关键词： Adversarial machine learning

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Classification of Stroke and Non-Stroke Patients from Human Body Movements using Smartphone Videos and Deep Neural Networks 14

Classification of Stroke and Non-Stroke Patients from Human ...

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14th International Conference on Advanced computer science and Information Systems, ICACSIS 2022

作者： Feliandra, Zafira Binta Khadijah, Siti Rachmadi, Muhammad Febrian Chahyati, Dina Universitas Indonesia Depok Faculty of Computer Science Depok Indonesia Brain Image Analysis Unit Riken Center for Brain Science Wako Wako Japan

ISBN: (数字)9781665489362

ISBN: (纸本)9781665489362

This study covers a pilot study on developing a tele-health system for detection and classification of stroke and non-stroke patients from human body movements using smartphone videos. Human body poses are extracted from smartphone videos which are then transformed into RGB images and classified into either stroke (positive) or non-stroke (negative) labels. We tested PoseNet, BlazePose, and MoveNet for human body pose detection and AlexN et and SqueezeN et for classification. From this pilot study, we found that MoveNet is the best human body pose detection while AlexNet is the best for classification. © 2022 IEEE.

关键词： Smartphones

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FedBCD: Federated Ultrasound Video and image Joint Learning for Breast Cancer Diagnosis

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IEEE Transactions on Medical Imaging 2025年第6期44卷 2395-2407页

作者： Deng, Tianpeng Huang, Chunwang Cai, Ming Liu, Yu Liu, Min Lin, Jiatai Shi, Zhenwei Zhao, Bingchao Huang, Jingqi Liang, Changhong Han, Guoqiang Liu, Zaiyi Wang, Ying Han, Chu South China University of Technology School of Computer Science and Engineering Guangdong Guangzhou510006 China Department of Ultrasound Guangzhou510080 China Department of Radiology Guangzhou510080 China Guangdong Prov. Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application Guangzhou510080 China Sun Yat-sen University Cancer Center Collaborative Innovation Center for Cancer Medicine Department of Ultrasound State Key Laboratory of Oncology in South China Guangzhou China The First Affiliated Hospital of Guangzhou Medical University Department of Medical Ultrasonics Guangzhou China

Ultrasonography plays an essential role in breast cancer diagnosis. Current deep learning based studies train the models on either images or videos in a centralized learning manner, lacking consideration of joint benefits between two different modality models or the privacy issue of data centralization. In this study, we propose the first decentralized learning solution for joint learning with breast ultrasound video and image, called FedBCD. To enable the model to learn from images and videos simultaneously and seamlessly in client-level local training, we propose a Joint Ultrasound Video and image Learning (JUVIL) model to bridge the dimension gap between video and image data by incorporating temporal and spatial adapters. The parameter-efficient design of JUVIL with trainable adapters and frozen backbone further reduces the computational cost and communication burden of federated learning, finally improving the overall efficiency. Moreover, considering conventional model-wise aggregation may lead to unstable federated training due to different modalities, data capacities in different clients, and different functionalities across layers. We further propose a Fisher information matrix (FIM) guided Layer-wise Aggregation method named FILA. By measuring layer-wise sensitivity with FIM, FILA assigns higher contributions to the clients with lower sensitivity, improving personalized performance during federated training. Extensive experiments on three image clients and one video client demonstrate the benefits of joint learning architecture, especially for the ones with small-scale data. FedBCD significantly outperforms nine federated learning methods on both video-based and image-based diagnoses, demonstrating the superiority and potential for clinical practice. Code is released at https://***/tianpeng-deng/FedBCD. © 1982-2012 IEEE.

关键词： Fisher information matrix

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Blockchain-Based Cognitive Computing Model for Data Security on a Cloud Platform

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computers, Materials & Continua 2023年第12期77卷 3305-3323页

作者： Xiangmin Guo Guangjun Liang Jiayin Liu Xianyi Chen Department of Computer Information and Cyber Security Jiangsu Police InstituteNanjing210031China Jiangsu Electronic Data Forensics and Analysis Engineering Research Center Jiangsu Police InstituteNanjing210031China School of Computer and Software Nanjing University of Information Science and TechnologyNanjing210044China

Cloud storage is widely used by large companies to store vast amounts of data and files,offering flexibility,financial savings,and ***,information shoplifting poses significant threats,potentially leading to poor performance and privacy ***-based cognitive computing can help protect and maintain information security and privacy in cloud platforms,ensuring businesses can focus on business *** ensure data security in cloud platforms,this research proposed a blockchain-based Hybridized Data Driven Cognitive Computing(HD2C)***,the proposed HD2C framework addresses breaches of the privacy information of mixed participants of the Internet of Things(IoT)in the ***2C is developed by combining Federated Learning(FL)with a Blockchain consensus algorithm to connect smart contracts with Proof of ***“Data Island”problem can be solved by FL’s emphasis on privacy and lightning-fast processing,while Blockchain provides a decentralized incentive structure that is impervious to *** with Blockchain allows quick consensus through smart member selection and *** HD2C paradigm significantly improves the computational processing efficiency of intelligent *** analysis results derived from IIoT datasets confirm HD2C *** compared to other consensus algorithms,the Blockchain PoA’s foundational cost is *** accuracy and memory utilization evaluation results predict the total benefits of the *** comparison to the values 0.004 and 0.04,the value of 0.4 achieves good *** to the experiment results,the number of transactions per second has minimal impact on memory *** findings of this study resulted in the development of a brand-new IIoT framework based on blockchain technology.

关键词： Blockchain Internet of Things(IoT) blockchain based cognitive computing Hybridized Data Driven Cognitive Computing(HD2C) Federated Learning(FL) Proof of Authority(PoA)

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There and back again: RDF as a bridge to domain-platforms like OMERO 15

There and back again: RDF as a bridge to domain-platforms li...

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15th International Conference on Semantic Web Applications and Tools for Health Care and Life sciences, SWAT4HCLS 2024

作者： Moore, Josh Waagmeester, Andra Hettne, Kristina Wolstencroft, Katherine Kunis, Susanne German BioImaging e.V. Society for Microscopy and Image Analysis Konstanz Germany Micelio Belgium Centre for Digital Scholarship Leiden University Libraries Netherlands Leiden Institute of Advanced Computer Science Netherlands Department of Biology/Chemistry Center for Cellular Nanoanalytics University Osnabrück Germany

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Multi-scale cyclical similarity prototype refinement for few-shot breast ultrasound image segmentation 17

Multi-scale cyclical similarity prototype refinement for few...

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17th IEEE International Conference on Signal Processing, ICSP 2024

作者： Ou, Yingfeng Yang, Xing Zhang, Jian Jian, Caiqing Wang, Lihui College of Computer Science and Technology Guizhou University Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province State Key Laboratory of Public Big Data Engineering Research Center of Text Computing Ministry of Education Guiyang China

ISBN: (纸本)9798350387384

Few-shot learning based methods can address the reliance on large-scale labeled samples in current breast tumor segmentation. However, previous methods typically rely on a few support samples to extract abstract, coarse-grained semantic prototypes, without considering the interaction between support and query data. In this study, we aim to provide each query image with relevant and information-rich support information. By integrating the difficult point selection module and the multi-scale cyclical prototype refinement module, we progressively refine coarse-grained support prototypes into more informative, fine-grained class prototypes, thereby better matching the highly variable breast ultrasound query data. Experiments on two datasets demonstrate that our proposed multi-scale cyclical similarity prototype refinement network (CSPRNet) achieves remarkable improvements compared to previous state-of-the-art methods. Specifically, using ResNet50 as the backbone, we achieve 57.93%/57.92% and 57.58%/59.24% mIoU for 1-shot and 5-shot segmentation, respectively, on public and private datasets, outperforming the suboptimal method by 8.18%/2.55% and 2.77%/4.48%. © 2024 IEEE.

关键词： Ultrasonic imaging

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A Reduced State-Space Generation Method for Concurrent Systems Based on CPN-PR Model

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IEEE Transactions on computer-Aided Design of Integrated Circuits and Systems 2025年第6期44卷 2328-2342页

作者： Zhong, Wenjie Sun, Tao Zhou, Jian-Tao Wang, Zhuowei Song, Xiaoyu Inner Mongolia University College of Computer Science the Engineering Research Center of Ecological Big Data Ministry of Education the Inner Mongolia Engineering Laboratory for Cloud Computing and Service Software the Inner Mongolia Engineering Laboratory for Big Data Analysis Technology Hohhot010000 China Guangdong University of Technology School of Computer Science and Technology Guangzhou510006 China Portland State University Department of Electrical and Computer Engineering PortlandOR97207 United States

Colored Petri nets (CPNs) provide descriptions of the concurrent behaviors for software and hardware. Model checking based on CPNs is an effective method to simulate and verify the concurrent behavior in system design. However, the model-checking method traverses the full state space, which suffers from the state-space explosion problem. A reduced state-space generation method related to the property of concurrent systems is proposed. Specifically, we extend CPNs to define a property-related model (CPN-PR) and give a property-related analysis method whose results can be used to generate the CPN-PR model. A reduced state-space generation method is developed based on enabled binding element filtering rules. The stutter trace equivalence between the state spaces of CPN and CPN-PR has been proven by showing that the reduced state space may not change the model-checking result. A comparison experiment is conducted to demonstrate the effectiveness of our method. © 1982-2012 IEEE.

关键词： Model checking

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Exploring Large Language Models for Analyzing Changes in Web Archive Content: A Retrieval-Augmented Generation Approach

Exploring Large Language Models for Analyzing Changes in Web...

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2024 IEEE International Conference on Big Data, BigData 2024

作者： Botello, Jhon G. Frew, Lesley Padilla, Jose J. Weigle, Michele C. Old Dominion University Department of Computer Science NorfolkVA United States Virginia Modeling Analysis and Simulation Center Old Dominion University NorfolkVA United States

ISBN: (纸本)9798350362480

Websites typically display only their most recent content. However, the dynamic nature of the web leads to frequent updates and deletions. Web archives preserve snapshots of earlier versions for those interested in tracking changes over time. Analyzing these changes often requires a manual process that relies on traditional methods focused on terms or phrase-level differences. This study explores the capability of Large Language Models (LLMs), specifically GPT-4o, through a Retrieval-Augmented Generation (RAG) approach for detecting changes in archived web pages. Using WARC-GPT, a RAG pipeline to interact with Web ARChive (WARC) files, we identify and analyze changes across a small set of U.S. federal environmental web pages that changed between 2016 and 2020. Our findings show that GPT-4o can effectively be used to detect inconsistencies in web archive content, including consideration of the change and the semantic context upon which the changes occurred. Our exploration represents an initial step toward using Artificial Intelligence (AI) for deeper and scalable web change analysis. © 2024 IEEE.

关键词： Semantics

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Semi-Supervised Gland Segmentation via Feature-Enhanced Contrastive Learning and Dual-Consistency Strategy

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IEEE Journal of Biomedical and Health Informatics 2025年第6期29卷 4314-4324页

作者： Yu, Jiejiang Li, Bingbing Pan, Xipeng Shi, Zhenwei Wang, Huadeng Lan, Rushi Luo, Xiaonan Guilin University of Electronic Technology School of Computer Science and Information Security Guilin541004 China Ganzhou Municipal Hospital Department of Pathology Ganzhou341000 China Southern Medical University Department of Radiology Guangdong Provincial People's Hospital Guangdong Academy of Medical Sciences Guangzhou510080 China Guangdong Provincial Key Laboratory of Artificial Intelligence in Medical Image Analysis and Application Guangzhou510080 China

In the field of gland segmentation in histopathology, deep-learning methods have made significant progress. However, most existing methods not only require a large amount of high-quality annotated data but also tend to confuse the internal of the gland with the background. To address this challenge, we propose a new semi-supervised method named DCCL-Seg for gland segmentation, which follows the teacher-student framework. Our approach can be divided into follows steps. First, we design a contrastive learning module to improve the ability of the student model's feature extractor to distinguish between gland and background features. Then, we introduce a Signed Distance Field (SDF) prediction task and employ dual-consistency strategy (across tasks and models) to better reinforce the learning of gland internal. Next, we proposed a pseudo label filtering and reweighting mechanism, which filters and reweights the pseudo labels generated by the teacher model based on confidence. However, even after reweighting, the pseudo labels may still be influenced by unreliable pixels. Finally, we further designed an assistant predictor to learn the reweighted pseudo labels, which do not interfere with the student model's predictor and ensure the reliability of the student model's predictions. Experimental results on the publicly available GlaS and CRAG datasets demonstrate that our method outperforms other semi-supervised medical image segmentation methods. © 2013 IEEE.

关键词： Contrastive Learning

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DFGET: Displacement-Field Assisted Graph Energy Transmitter for Gland Instance Segmentation 17

DFGET: Displacement-Field Assisted Graph Energy Transmitter ...

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17th IEEE International Conference on Signal Processing, ICSP 2024

作者： Jian, Caiqing Qin, Yongbin Wang, Lihui Ye, Chen Cheng, Xinyu Guizhou University Engineering Research Center of Text Computing & Cognitive Intelligence Ministry of Education Key Laboratory of Intelligent Medical Image Analysis and Precise Diagnosis of Guizhou Province State Key Laboratory of Public Big Data College of Computer Science and Technology Guiyang China

ISBN: (纸本)9798350387384

Gland instance segmentation is an essential but challenging task in the diagnosis of adenocarcinoma. The existing models usually achieve gland instance segmentation through multi-task learning and boundary loss constraint. However, how to deal with the problems of gland adhesion and inaccurate boundary in segmenting the complex samples remains a challenge. In this work, we propose a novel geometric feature named displacement field (DF), which can represent the geometric information such as shape, size, and orientation of the glands. Based on the explicit constraint of DF, a displacement-field assisted graph energy transmitter (DFGET) framework is proposed for solving the above problems. Using such graph framework, the gland semantic segmentation map and the displacement field of the graph nodes are estimated with two graph network branches. With the constraint of DF, a graph cluster module is presented to improve the intra-class feature consistency and inter-class feature discrepancy, as well as to separate the adherent glands. Extensive comparison and ablation experiments on the GlaS dataset demonstrate the effectiveness of the displacement field and the superiority of DFGET. Compared to the best comparative model, DFGET increases the object-Dice and object-F1 score by 2.27% and 3.11% respectively, while decreases the object-HD by 15.58, achieving state-of-the-art performance, which indicates that DFGET can serve as an auxiliary tool for the diagnosis of adenocarcinoma. © 2024 IEEE.

关键词： Semantic Segmentation

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