Marketplace development is increasing, as is the number of people with active internet access. Unive is a startup that runs an e-commerce platform connecting Student Activity Units with consumers. Focuses on fostering...
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Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/***1,KAT6...
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Bromodomain and plant homeodomain(PHD)finger containing protein 1(Brpf1)is an activator and scaffold protein of a multiunit complex that includes other components involving lysine acetyltransferase(KAT)6A/6B/***1,KAT6A,and KAT6B mutations were identified as the causal genes of neurodevelopmental disorders leading to intellectual *** previous work revealed strong and specific expression of Brpf1 in both the postnatal and adult forebrain,especially the hippocampus,which has essential roles in learning and ***,we hypothesized that Brpf1 plays critical roles in the function of forebrain excitatory neurons,and that its deficiency leads to learning and memory *** test this,we knocked out Brpf1 in forebrain excitatory neurons using *** found that Brpf1 deficiency reduced the frequency of miniature excitatory postsynaptic currents and downregulated the expression of genes Pcdhgb1,Slc16a7,Robo3,and Rho,which are related to neural development,synapse function,and memory,thereby damaging spatial and fear memory in *** findings help explain the mechanisms of intellectual impairment in patients with BRPF1 mutation.
It is intuitive to believe that humans take considerations of mental effort into account when making decisions. However, it has proved difficult to differentiate theories of mental effort in the absence of direct meas...
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"Talk moves" are specific discursive strategies used by teachers and students to facilitate conversations in which students share their thinking, and actively consider the ideas of others, and engage in rich...
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News gives new insight and information from all over the world. News has many categories, such as politic, economy, science, and other common news categories. Every news will have their own category based on its conte...
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Algorithm development on skin diseases identification with high cardinality classification is still very challenging. In addition, the high similarity appearance among diseases makes the computer vision approach meet ...
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The performance of automatic speech recognition (ASR) systems severely degrades when multi-talker speech overlap occurs. In meeting environments, speech separation is typically performed to improve the robustness of A...
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One of the major tasks of natural language processing is sentiment analysis. The web is a source of unstructured and rich informa-tion with thousands of opinions and reviews. Individuals, businesses, and governments c...
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Conventionally, assessing people's personality done by psychology experts requires more time and effort. Hence automatic personality prediction is starting to get noticed by researchers. Nowadays, many people enga...
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The Central Pattern Generator (CPG) is adept at generating rhythmic gait patterns characterized by consistent timing and adequate foot clearance. Yet, its open-loop configuration often fails to adjust the system's...
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