In this study, we initiated an approach to predict Protein Secondary Structure Prediction (PSSP) by using n-grams modeling, namely $n$ adjacent amino acid sequences, to represent the amino acid sequence and 1-Dimens...
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ISBN:
(数字)9798350373332
ISBN:
(纸本)9798350373349
In this study, we initiated an approach to predict Protein Secondary Structure Prediction (PSSP) by using n-grams modeling, namely
$n$
adjacent amino acid sequences, to represent the amino acid sequence and 1-Dimensional Convolutional Neural Network (CNN). We compare n-grams with a one-hot encoding approach and find that n-grams provide better performance. The analysis results show that bigrams are more effective than trigrams in describing protein amino acid sequence patterns. We also combine it with the PSSM profile feature to improve model performance. The results of this study reveal that the n-grams approach, especially bigrams, in combination with PSSM, can produce more accurate protein secondary structure predictions than previous models, with superior accuracy evaluations of Q8 68.1 % and Q3 82.75
%
on the CB513 dataset.
Preventing agricultural resource loss caused by pests remains a crucial issue. While technological advancements are being achieved, the current agricultural management methods and equipment have yet to meet the requir...
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Neuroradiology studies often suffer from lack of sufficient data to properly train deep learning models. Generative Adversarial Networks (GANs) can mitigate this problem by generating synthetic images to augment train...
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Mild cognitive Impairment (MCI) is a condition that often precedes dementia, making early diagnosis critical for delaying cognitive decline. Electroencephalography (EEG) has emerged as a non-invasive, cost-effective t...
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In the digital era, digital talent development has become increasingly vital for organizations and economies to thrive. While much focus has been placed on technical skills, this report emphasizes the often-overlooked...
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Circular dichroism(CD)spectroscopy has been widely demonstrated for detecting chiral ***,the determination of chiral mixtures with various concentrations and enantiomeric ratios can be a challenging *** solve this pro...
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Circular dichroism(CD)spectroscopy has been widely demonstrated for detecting chiral ***,the determination of chiral mixtures with various concentrations and enantiomeric ratios can be a challenging *** solve this problem,we report an enhanced vibrational circular dichroism(VCD)sensing platform based on plasmonic chiral metamaterials,which presents a 6-magnitude signal enhancement with a selectivity of chiral *** by coupled-mode theory,we leverage both in-plane and out-of-plane symmetry-breaking structures for chiral metamaterial design enabled by a two-step lithography process,which increases the near-field coupling strengths and varies the ratio between absorption and radiation loss,resulting in improved chiral light-matter interaction and enhanced molecular VCD ***,we demonstrate the thin-film sensing process of BSA andβ-lactoglobulin proteins,which contain secondary structures a-helix andβ-sheet and achieve a limit of detection down to zeptomole ***,we also,for the first time,explore the potential of enhanced VCD spectroscopy by demonstrating a selective sensing process of chiral mixtures,where the mixing ratio can be successfully differentiated with our proposed chiral *** findings improve the sensing signal of molecules and expand the extractable information,paving the way toward label-free,compact,small-volume chiral molecule detection for stereochemical and clinical diagnosisapplications.
Understanding connections between artificial and biological intelligent systems can reveal fundamental principles of general intelligence. While many artificial intelligence models have a neuroscience counterpart, suc...
Human-Centered learning analytics (HCLA) is an approach that emphasizes the human factors in learning analytics and truly meets user needs. User involvement in all stages of the design, analysis, and evaluation of lea...
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Air-side economizers are increasingly used to take advantage of“free-cooling”in data centers with the intent of reducing the carbon footprint of ***,they can introduce outdoor pollutants to indoor environment of dat...
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Air-side economizers are increasingly used to take advantage of“free-cooling”in data centers with the intent of reducing the carbon footprint of ***,they can introduce outdoor pollutants to indoor environment of data centers and cause corrosion damage to the information technology *** evaluate the reliability of information technology equipment under various thermal and air-pollution conditions,a mechanistic model based on multi-ion transport and chemical reactions was *** model was used to predict Cu corrosion caused by Cl_(2)-containing pollutant *** also accounted for the effects of temperature(25℃and 28℃),relative humidity(50%,75%,and 95%),and *** also identified higher air temperature as a corrosion barrier and higher relative humidity as a corrosion accelerator,which agreed well with the experimental *** average root mean square error of the prediction was 13.7Å.The model can be used to evaluate the thermal guideline for data centers design and operation when Cl_(2)is present based on pre-established acceptable risk of corrosion in data centers’environment.
Currently, Indonesia and the whole world are being hit by the Covid-19 pandemic which has an impact on various fields of life. It affects all sectors, including the education sector. The government through the Ministr...
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Currently, Indonesia and the whole world are being hit by the Covid-19 pandemic which has an impact on various fields of life. It affects all sectors, including the education sector. The government through the Ministry of Education and Culture makes a policy in education in terms of the learning process. Teaching and learning activities that were initially carried out face to face become distance learning which was carried out at home. In this study, a systematic literature review is conducted on automatic assessment of essay answers. Various previous studies discuss the essay answer scoring system that has been developed using various methods. We synthesize the results to enrich our understanding of the automated essay exam scoring system. The expected result of this research is that it can contribute to further research related to the automated essay exam scoring system, especially in terms of considering methods and dataset forms.
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