This study explores the feasibility of using large language models (LLMs), specifically GPT-4o (ChatGPT), for automated grading of conceptual questions in an undergraduate Mechanical engineering course. We compared th...
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As the dengue infection still impacts hundreds of millions of people globally, unprecedented efforts in dengue drug development have been more progressive in recent decades. Computational methods provide a fast, susta...
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As the dengue infection still impacts hundreds of millions of people globally, unprecedented efforts in dengue drug development have been more progressive in recent decades. Computational methods provide a fast, sustainable, and efficient screening of active compounds and newly created drug molecules, including those specifically targeting nonstructural proteins (NS) of dengue viruses. In this work, protein modeling for the NS proteins of DENV-2/16681 strain was performed using a template-based homology modeling for the NS3 protein and an Artificial Intelligence (AI)-based prediction via AlphaFold for the NS4B protein. Moreover, the protein-protein interaction between the two structures was predicted using the HADDOCK server, which employs information about active and passive residues of the interaction interface to guide the docking process. After the modeling and its respective refinement process, the predicted structures of NS3 and NS4B improved their steric clashing scoring from MolProbity assessment. The refined models were then docked, and the resulting docking pose was analyzed to extract the interacting residues based on the polar contacts within the interface of the two proteins. Our result presents a preliminary study to create a dataset related to in silico molecular interactions of the NS3-NS4B interaction of different DENV types. It is helpful for building a computational pipeline for elucidating protein-ligand problems in dengue drug screenings.
The meaning of a slang term can vary in different communities. However, slang semantic variation is not well understood and under-explored in the natural language processing of slang. One existing view argues that sla...
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This paper investigates the effect of bitrate control methods on QoE of multi-view video and audio streaming with MPEG-DASH. We adopt three bitrate control methods for conventional single-view video streaming to the M...
This paper investigates the effect of bitrate control methods on QoE of multi-view video and audio streaming with MPEG-DASH. We adopt three bitrate control methods for conventional single-view video streaming to the MVV-A system with MPEG-DASH. We conduct a subjective experiment changing available network bandwidth and investigate the effect of the methods on QoE.
This paper evaluates the QoE of video and audio transmission over a full-duplex wireless LAN with interference traffic through a computer simulation and a subjective experiment. We employ a simulation environment with...
This paper evaluates the QoE of video and audio transmission over a full-duplex wireless LAN with interference traffic through a computer simulation and a subjective experiment. We employ a simulation environment with a pair of audiovisual transmission and reception terminals and a pair of interference traffic transmission and reception ones. We investigate the effect of the transmission rate of interference traffic and communication distance in a wireless channel on the output quality of the video and audio stream at the reception terminal. We perform a subjective experiment with the output timing of video and audio obtained by the simulation.
作者:
Guo, KuoLi, YifanChen, HaoShen, Hong-BinYang, YangShanghai Jiao Tong University
Key Lab. of Shanghai Education Commission for Intelligent Interaction and Cognitive Engineering Department of Computer Science and Engineering Shanghai200240 China Shanghai Jiao Tong University
Key Laboratory of System Control and Information Processing Ministry of Education of China Institute of Image Processing and Pattern Recognition Shanghai200240 China Carnegie Mellon University
School of Computer Science Computational Biology Department PittsburghPA15213 United States
Isoforms refer to different mRNA molecules transcribed from the same gene, which can be translated into proteins with varying structures and functions. Predicting the functions of isoforms is an essential topic in bio...
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A future networking design called "software-defined networking"combines network programmability with centralized administration (SDN). Network administration is currently handled by SDN, which, at the regula...
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Recently, cooking oil has been widely discussed on social media. Many people ask how to analyze this phenomenon, one of which is using a sentiment analysis application on Twitter that performs a scientific analysis of...
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This paper presents our system for the BioASQ10b Phase B task. For ideal answers, we used the fine-tuned BioBERT model on the MNLI dataset to construct sentence embeddings and combined it with BERTScore to select sent...
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Edge intelligent computing is often combined with the tasks of Unmanned Aerial Vehicle (UAV). Most applications of UAV require the location and identity information of human targets. Traditional human target detection...
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