Identifying drug–target interactions (DTIs) is a critical step in both drug repositioning. The labor-intensive, time-consuming, and costly nature of classic DTI laboratory studies makes it imperative to create effici...
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This study proposes a hybrid optimization-based mobility management strategy employing Kinetic Gas Molecular Optimization (KGMO) and Ant Lion Optimization (ALO). Initially, KGMO calculates particle properties, such as...
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Online shopping has become an integral part of modern consumer culture. Yet, it is plagued by challenges in visualizing clothing items based on textual descriptions and estimating their fit on individual body types. I...
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Online shopping has become an integral part of modern consumer culture. Yet, it is plagued by challenges in visualizing clothing items based on textual descriptions and estimating their fit on individual body types. In this work, we present an innovative solution to address these challenges through text-driven clothed human image synthesis with 3D human model estimation, leveraging the power of Vector Quantized Variational AutoEncoder (VQ-VAE). Creating diverse and high-quality human images is a crucial yet difficult undertaking in vision and graphics. With the wide variety of clothing designs and textures, existing generative models are often not sufficient for the end user. In this proposed work, we introduce a solution that is provided by various datasets passed through several models so the optimized solution can be provided along with high-quality images with a range of postures. We use two distinct procedures to create full-body 2D human photographs starting from a predetermined human posture. 1) The provided human pose is first converted to a human parsing map with some sentences that describe the shapes of clothing. 2) The model developed is then given further information about the textures of clothing as an input to produce the final human image. The model is split into two different sections the first one being a codebook at a coarse level that deals with overall results and a fine-level codebook that deals with minute detailing. As mentioned previously at fine level concentrates on the minutiae of textures, whereas the codebook at the coarse level covers the depictions of textures in structures. The decoder trained together with hierarchical codebooks converts the anticipated indices at various levels to human images. The created image can be dependent on the fine-grained text input thanks to the utilization of a blend of experts. The quality of clothing textures is refined by the forecast for finer-level indexes. Implementing these strategies can result
Nowadays, Cloud Computing has attracted a lot of interest from both individual users and organization. However, cloud computing applications face certain security issues, such as data integrity, user privacy, and serv...
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Load balancing and scheduling are essential components of cloud computing that aim to optimize resource allocation and utilization. In a cloud environment, multiple virtual machines and applications compete for shared...
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The disappearance of Indigenous languages results in a decrease in cultural diversity, hence making the preservation of these languages extremely important. Conventional methods of documentation are lengthy, and the p...
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Drug-target interactions(DTIs) prediction plays an important role in the process of drug *** computational methods treat it as a binary prediction problem, determining whether there are connections between drugs and t...
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Drug-target interactions(DTIs) prediction plays an important role in the process of drug *** computational methods treat it as a binary prediction problem, determining whether there are connections between drugs and targets while ignoring relational types information. Considering the positive or negative effects of DTIs will facilitate the study on comprehensive mechanisms of multiple drugs on a common target, in this work, we model DTIs on signed heterogeneous networks, through categorizing interaction patterns of DTIs and additionally extracting interactions within drug pairs and target protein pairs. We propose signed heterogeneous graph neural networks(SHGNNs), further put forward an end-to-end framework for signed DTIs prediction, called SHGNN-DTI,which not only adapts to signed bipartite networks, but also could naturally incorporate auxiliary information from drug-drug interactions(DDIs) and protein-protein interactions(PPIs). For the framework, we solve the message passing and aggregation problem on signed DTI networks, and consider different training modes on the whole networks consisting of DTIs, DDIs and PPIs. Experiments are conducted on two datasets extracted from Drug Bank and related databases, under different settings of initial inputs, embedding dimensions and training modes. The prediction results show excellent performance in terms of metric indicators, and the feasibility is further verified by the case study with two drugs on breast cancer.
Purpose: The rapid spread of COVID-19 has resulted in significant harm and impacted tens of millions of people globally. In order to prevent the transmission of the virus, individuals often wear masks as a protective ...
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This systematic review gave special attention to diabetes and the advancements in food and nutrition needed to prevent or manage diabetes in all its forms. There are two main forms of diabetes mellitus: Type 1 (T1D) a...
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As modern communication technology advances apace,the digital communication signals identification plays an important role in cognitive radio networks,the communication monitoring and management *** has become a promi...
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As modern communication technology advances apace,the digital communication signals identification plays an important role in cognitive radio networks,the communication monitoring and management *** has become a promising solution to this problem due to its powerful modeling capability,which has become a consensus in academia and ***,because of the data-dependence and inexplicability of AI models and the openness of electromagnetic space,the physical layer digital communication signals identification model is threatened by adversarial *** examples pose a common threat to AI models,where well-designed and slight perturbations added to input data can cause wrong ***,the security of AI models for the digital communication signals identification is the premise of its efficient and credible *** this paper,we first launch adversarial attacks on the end-to-end AI model for automatic modulation classifi-cation,and then we explain and present three defense mechanisms based on the adversarial *** we present more detailed adversarial indicators to evaluate attack and defense ***,a demonstration verification system is developed to show that the adversarial attack is a real threat to the digital communication signals identification model,which should be paid more attention in future research.
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