Deep learning approaches have attained remarkable success across various artificial intelligence applications, spanning healthcare, finance, and autonomous vehicles, profoundly impacting human existence. However, thei...
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Descriptors play a pivotal role in enzyme design for the greener synthesis of biochemicals,as they could characterize enzymes and chemicals from the physicochemical and evolutionary *** study examined the effects of v...
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Descriptors play a pivotal role in enzyme design for the greener synthesis of biochemicals,as they could characterize enzymes and chemicals from the physicochemical and evolutionary *** study examined the effects of various descriptors on the performance of Random Forest model used for enzyme-chemical relationships *** curated activity data of seven specific enzyme families from the literature and developed the pipeline for evaluation the machine learning model performance using 10-fold *** influence of protein and chemical descriptors was assessed in three scenarios,which were predicting the activity of unknown relations between known enzymes and known chemicals(new relationship evaluation),predicting the activity of novel enzymes on known chemicals(new enzyme evaluation),and predicting the activity of new chemicals on known enzymes(new chemical evaluation).The results showed that protein descriptors significantly enhanced the classification performance of model on new enzyme evaluation in three out of the seven datasets with the greatest number of enzymes,whereas chemical descriptors appear no effect.A variety of sequence-based and structure-based protein descriptors were constructed,among which the esm-2 descriptor achieved the best *** enzyme families as labels showed that descriptors could cluster proteins well,which could explain the contributions of descriptors to the machine learning *** a counterpart,in the new chemical evaluation,chemical descriptors made significant improvement in four out of the seven datasets,while protein descriptors appear no *** attempted to evaluate the generalization ability of the model by correlating the statistics of the datasets with the performance of the *** results showed that datasets with higher sequence similarity were more likely to get better results in the new enzyme evaluation and datasets with more enzymes were more likely beneficial from the protein
Graph neural networks (GNNs) have gained increasing popularity, while usually suffering from unaffordable computations for real-world large-scale applications. Hence, pruning GNNs is of great need but largely unexplor...
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Graph neural networks (GNNs) have gained increasing popularity, while usually suffering from unaffordable computations for real-world large-scale applications. Hence, pruning GNNs is of great need but largely unexplored. The recent work Unified GNN Sparsification (UGS) studies lottery ticket learning for GNNs, aiming to find a subset of model parameters and graph structures that can best maintain the GNN performance. However, it is tailed for the transductive setting, failing to generalize to unseen graphs, which are common in inductive tasks like graph classification. In this work, we propose a simple and effective learning paradigm, Inductive Co-Pruning of GNNs (ICPG), to endow graph lottery tickets with inductive pruning capacity. To prune the input graphs, we design a predictive model to generate importance scores for each edge based on the input. To prune the model parameters, it views the weight’s magnitude as their importance scores. Then we design an iterative co-pruning strategy to trim the graph edges and GNN weights based on their importance scores. Although it might be strikingly simple, ICPG surpasses the existing pruning method and can be universally applicable in both inductive and transductive learning settings. On 10 graph-classification and two node-classification benchmarks, ICPG achieves the same performance level with 14.26%–43.12% sparsity for graphs and 48.80%–91.41% sparsity for the GNN model.
A progressive neurodegenerative ailment called Parkinson's disease (PD) is marked by the death of dopamine-producing cells in the substantia nigra area of the brain. The exact etiology of PD remains elusive, but i...
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Sarcasm in social media postings significantly impacts automated sentiment extraction due to its potential to invert the overall polarity of phrases. It poses a formidable challenge in extracting genuine sentiments fr...
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The use of machine learning models in intrusion detection systems (IDSs) takes more time to build the model with many features and degrade the performance. The present paper proposes an ensemble of filter feature sele...
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Scientific community understanding of the variance in severity of infectious disease like COVID-19 across patients is an important area of focus. The article presents an innovative voting ensemble GenoCare Prognostica...
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Large-scale indoor 3D reconstruction with multiple robots faces challenges in core enabling *** work contributes to a framework addressing localization,coordination,and vision processing for multi-agent reconstruction...
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Large-scale indoor 3D reconstruction with multiple robots faces challenges in core enabling *** work contributes to a framework addressing localization,coordination,and vision processing for multi-agent reconstruction.A system architecture fusing visible light positioning,multi-agent path finding via reinforcement learning,and 360°camera techniques for 3D reconstruction is *** visible light positioning algorithm leverages existing lighting for centimeter-level localization without additional ***,a decentralized reinforcement learning approach is developed to solve the multi-agent path finding problem,with communications among agents *** 3D reconstruction pipeline utilizes equirectangular projection from 360°cameras to facilitate depth-independent reconstruction from posed monocular images using neural *** validation demonstrates centimeter-level indoor navigation and 3D scene reconstruction capabilities of our *** challenges and limitations stemming from the above enabling technologies are discussed at the end of each corresponding *** summary,this research advances fundamental techniques for multi-robot indoor 3D modeling,contributing to automated,data-driven applications through coordinated robot navigation,perception,and modeling.
Deepfake detection aims to mitigate the threat of manipulated content by identifying and exposing forgeries. However, previous methods primarily tend to perform poorly when confronted with cross-dataset scenarios. To ...
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The Salp swarm algorithm (SSA) simulates how salps forage and travel in the ocean. SSA suffers from low initial population diversity, improper balancing of exploration and exploitation, and slow convergence speed. Thu...
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