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Exploring Unbiased Activation Maps for Weakly Supervised Tissue Segmentation of Histopathological Images

IEEE Transactions on Medical Imaging 2025年第6期44卷 2631-2642页

作者： Kang, Yuxin Li, Hansheng Shi, Xiaoshuang Zhang, Xiao Xing, Yaqiong Wen, Yuting Wang, Yi Cui, Lei Feng, Jun Yang, Lin Yulin University Department of Information Engineering Shaanxi Yulin China The School of Information Science and Technology Northwest University Shaanxi Xi'an China Northwest University School of Information Science and Technology Shaanxi Xi'an China University of Electronic Science and Technology of China Department of Computer Science and Engineering Sichuan Chengdu China Xi'An Jiaotong University School of Computer Science and Technology Shaanxi Xi'an China

Tissue segmentation in histopathological images plays a crucial role in computational pathology, owing to its significant potential to indicate the prognosis of cancer patients. Presently, numerous Weakly Supervised Semantic Segmentation (WSSS) methods strive to utilize image-level labels to achieve pixel-level segmentation, aiming to minimize the need for detailed annotations. Most of these methods rely on Class Activation Maps (CAM) extracted from classification models, frequently leading to poor coverage of objects. The major cause is attributed to the strong inductive bias of the classification model, focusing primarily on discriminative feature of objects, rather than non-discriminative features. Inspired by this, we propose a simple yet effective method that introduces a self-supervised task by exploiting both the discriminative and non-discriminative features, and generate Unbiased Activation Maps (UAM) to encompass the whole object. Specifically, our method entails clustering all spatial features of an object class to derive semantic centers. Each center then works as a spatial filter that amplifies similar feature and suppresses dissimilar feature, and extract high-quality pseudo-labels (some noise at object boundaries). Moreover, we further propose a Noise-Reduced (NR) Learning method to train the segmentation network towards credible signals and lessen the impact of false predictions. Comprehensive experimental results on two public histopathology image datasets demonstrate the superior performance of our method over the state-of-the-art weakly supervised segmentation methods. © 2025 IEEE. All rights reserved.

关键词： Semantic Segmentation

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Contemporary Study for Detection of COVID-19 Using Machine Learning with Explainable AI

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computers, Materials & Continua 2024年第7期80卷 1075-1104页

作者： Saad Akbar Humera Azam Sulaiman Sulmi Almutairi Omar Alqahtani Habib Shah Aliya Aleryani Department of Computer Science University of KarachiKarachi75270Pakistan Department of Computing Faculty of Engineering Science and TechnologyHamdard UniversityKarachi75540Pakistan Department of Health Informatics College of Applied Medical SciencesQassim UniversityQassim51452Saudi Arabia Department of Computer Science College of Computer ScienceKing Khalid UniversityAbha61421Saudi Arabia

The prompt spread of COVID-19 has emphasized the necessity for effective and precise diagnostic *** this article,a hybrid approach in terms of datasets as well as the methodology by utilizing a previously unexplored dataset obtained from a private hospital for detecting COVID-19,pneumonia,and normal conditions in chest X-ray images(CXIs)is proposed coupled with Explainable Artificial Intelligence(XAI).Our study leverages less preprocessing with pre-trained cutting-edge models like InceptionV3,VGG16,and VGG19 that excel in the task of feature *** methodology is further enhanced by the inclusion of the t-SNE(t-Distributed Stochastic Neighbor Embedding)technique for visualizing the extracted image features and Contrast Limited Adaptive Histogram Equalization(CLAHE)to improve images before extraction of ***,an AttentionMechanism is utilized,which helps clarify how the modelmakes decisions,which builds trust in artificial intelligence(AI)*** evaluate the effectiveness of the proposed approach,both benchmark datasets and a private dataset obtained with permissions from Jinnah PostgraduateMedical Center(JPMC)in Karachi,Pakistan,are *** 12 experiments,VGG19 showcased remarkable performance in the hybrid dataset approach,achieving 100%accuracy in COVID-19 *** classification and 97%in distinguishing normal ***,across all classes,the approach achieved 98%accuracy,demonstrating its efficiency in detecting COVID-19 and differentiating it fromother chest disorders(Pneumonia and healthy)while also providing insights into the decision-making process of the models.

关键词： COVID-19 detection deep neural networks support vector machine CXIs InceptionV3 VGG16 VGG19 t-SNE embedding CLAHE attention mechanism XAI

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Private, Accurate and Communication Efficient Clustering Over Vertically Distributed Dataset

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IEEE Transactions on Information Forensics and Security 2025年 20卷 5094-5108页

作者： Yuan, Shaoxian Xue, Kaiping Zhao, Jingcheng Wei, David S.L University of Science and Technology of China School of Cyber Science and Technology Anhui Hefei230027 China Fordham University Department of Computer and Information Science BronxNY10458 United States

Clustering is a crucial unsupervised machine learning algorithm extensively used in various practical applications, such as patient refinement and fraud detection, which often involve vertically distributed data across multiple data centers. However, sharing datasets directly is typically prohibited under GDPR due to potential privacy breaches. Therefore, privacy-preserving joint clustering for vertically distributed datasets is highly desired. In this paper, we propose Privacy-Preserving Vertically Federated Clustering (PPVFC), a solution that not only achieves this goal but also significantly reduces computational and communication overhead for each data owner (DO). Unlike most previous works that achieve the goal with a single privacy-enhancing technology, PPVFC jointly leverages multiparty homomorphic encryption (MHE) and multiparty computation (MPC) to efficiently interleave communication-lightweight homomorphic computations on the local dataset with operations over collectively secret-shared intermediate data. Specifically, we design a coefficient-wise encoding for MHE to pack large datasets and minimize communication costs. Additionally, we develop a round-efficient bit extraction protocol for determining the minimum distance. Through extensive experiments and security analysis, we demonstrate the practical performance and robust security guarantees of PPVFC. © 2005-2012 IEEE.

关键词： Learning algorithms

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ONLINE PRIMAL DUAL MEETS ONLINE MATCHING WITH STOCHASTIC REWARDS: CONFIGURATION LP TO THE RESCUE

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SIAM Journal on Computing 2024年第5期53卷 1217-1256页

作者： Huang, Zhiyi Zhang, Qiankun Department of Computer Science The University of Hong Kong Hong Kong School of Cyber Science and Engineering Huazhong University of Science and Technology Wuhan China

Mehta and Panigrahi (FOCS 2012, IEEE, Piscataway, NJ, 2012, pp. 728-737) introduce the problem of online matching with stochastic rewards, where edges are associated with success probabilities and a match succeeds with the probability of the corresponding edge. It is one of the few online matching problems that have defied the randomized online primal dual framework by Devanur, Jain, and Kleinberg (SODA 2013, SIAM, Philadelphia, 2013, pp. 101-107) thus far. This paper unlocks the power of randomized online primal dual in online matching with stochastic rewards by employing the configuration linear program rather than the standard matching linear program used in previous works. Our main result is a 0.572 competitive algorithm for the case of vanishing and unequal probabilities, improving the best previous bound of 0.534 by Mehta, Waggoner, and Zadimoghaddam (SODA 2015, SIAM, Philadelphia, 2015, pp. 1388-1404) and, in fact, is even better than the best previous bound of 0.567 by Mehta and Panigrahi (FOCS 2012, IEEE, Piscataway, NJ, 2012, pp. 728-737) for the more restricted case of vanishing and equal probabilities. For vanishing and equal probabilities, we get a better competitive ratio of 0.576. Our results further generalize to the vertex-weighted case due to the intrinsic robustness of the randomized online primal dual analysis. © 2024 Society for Industrial and Applied Mathematics.

关键词： Consensus algorithm

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Enhanced thyroid disease prediction using ensemble machine learning: a high-accuracy approach with feature selection and class balancing

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Discover Artificial Intelligence 2025年第1期5卷 1-29页

作者： Islam, Md. Rezaul Chowdhury, Aniruddha Islam Shama, Sharmin Lamyea, Md. Masudul Hasan Department of Computer Science and Engineering Shahjalal University of Science and Technology Sylhet3114 Bangladesh Department of Educational Technology and Engineering Bangabandhu Sheikh Mujibur Rahman Digital University Gazipur1750 Bangladesh Department of Computer Science and Engineering Dhaka International University Dhaka1212 Bangladesh

Thyroid disorders are increasingly prevalent, making early detection crucial for reducing mortality and complications. Accurate prediction of disease progression and understanding the interplay of clinical features are essential for effective diagnosis and treatment. Our study addresses these challenges by employing a standard machine learning model, enhanced with comprehensive clinical feature analysis and an ensemble learning technique. By leveraging machine learning, we can identify key risk factors and improve diagnostic accuracy. To achieve optimal prediction outcomes, we evaluated seventeen machine learning models and implemented an Ensemble ML classifier using a hard voting strategy. Class balancing techniques, particularly random oversampling, significantly improved classification performance. Our experimental results demonstrate that the proposed model outperforms existing methods, achieving 100% sensitivity and 99.72% accuracy using the XGBoost algorithm and SelectKBest feature selection. By addressing feature reduction and high class-imbalance, the ensemble ML classifier with hard voting proves more effective in handling classification challenges. © The Author(s) 2025.

关键词： Adversarial machine learning

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Ensemble Deep Learning Approaches in Health Care:A Review

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computers, Materials & Continua 2025年第3期82卷 3741-3771页

作者： Aziz Alotaibi Department of Computer Science College of Computing and Information TechnologyTaif UniversityTaif21974Saudi Arabia

Deep learning algorithms have been rapidly incorporated into many different applications due to the increase in computational power and the availability of massive amounts of ***,both deep learning and ensemble learning have been used to recognize underlying structures and patterns from high-level features to make predictions/*** the growth in popularity of deep learning and ensemble learning algorithms,they have received significant attention from both scientists and the industrial community due to their superior ability to learn features from big *** deep learning has exhibited significant performance in enhancing learning generalization through the use of multiple deep learning *** ensemble deep learning has large quantities of training parameters,which results in time and space overheads,it performs much better than traditional ensemble *** deep learning has been successfully used in several areas,such as bioinformatics,finance,and health *** this paper,we review and investigate recent ensemble deep learning algorithms and techniques in health care domains,medical imaging,health care data analytics,genomics,diagnosis,disease prevention,and drug *** cover several widely used deep learning algorithms along with their architectures,including deep neural networks(DNNs),convolutional neural networks(CNNs),recurrent neural networks(RNNs),and generative adversarial networks(GANs).Common healthcare tasks,such as medical imaging,electronic health records,and genomics,are also ***,in this review,the challenges inherent in reducing the burden on the healthcare system are discussed and ***,future directions and opportunities for enhancing healthcare model performance are discussed.

关键词： Deep learning ensemble learning deep ensemble learning deep learning approaches for health care health care

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Dynamic Spatial Focus in Alzheimer’s Disease Diagnosis via Multiple CNN Architectures and Dynamic GradNet

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computers, Materials & Continua 2025年第5期83卷 2109-2142页

作者： Jasem Almotiri Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

The evolving field of Alzheimer’s disease(AD)diagnosis has greatly benefited from deep learning models for analyzing brain magnetic resonance(MR)*** study introduces Dynamic GradNet,a novel deep learning model designed to increase diagnostic accuracy and interpretability for multiclass AD ***,four state-of-the-art convolutional neural network(CNN)architectures,the self-regulated network(RegNet),residual network(ResNet),densely connected convolutional network(DenseNet),and efficient network(EfficientNet),were comprehensively compared via a unified preprocessing pipeline to ensure a fair *** these models,EfficientNet consistently demonstrated superior performance in terms of accuracy,precision,recall,and F1 *** a result,EfficientNetwas selected as the foundation for implementing Dynamic *** GradNet incorporates gradient weighted class activation mapping(GradCAM)into the training process,facilitating dynamic adjustments that focus on critical brain regions associated with early dementia *** adjustments are particularly effective in identifying subtle changes associated with very mild dementia,enabling early diagnosis and *** model was evaluated with the OASIS dataset,which contains greater than 80,000 brain MR images categorized into four distinct stages of AD *** proposed model outperformed the baseline architectures,achieving remarkable generalizability across all *** findingwas especially evident in early-stage dementia detection,where Dynamic GradNet significantly reduced false positives and enhanced classification *** findings highlight the potential of Dynamic GradNet as a robust and scalable approach for AD diagnosis,providing a promising alternative to traditional attention-based *** model’s ability to dynamically adjust spatial focus offers a powerful tool in artificial intelligence(AI)assisted precisionmedicine,particularly in the early det

关键词： Spatial focus GradCAM medical image classification deep learning early dementia detection neurodegenerative disease MRI analysis Alzheimer’s attention CNN

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Improved Harmony Search Algorithm for SDN Controller Placement

Iraqi Journal for Computer Science and Mathematics

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Iraqi Journal for computer science and Mathematics 2025年第2期6卷 167-179页

作者： Aldeen, Yousra Abdul Alsahib S. Sadiq, Ahmed T. Abed, Abeer E. Hussain, Omar F. Madni, Syed Hamid Hussain Department of Computer Science College of Science for Women University of Baghdad Iraq Department of Computer Science University of Technology Iraq Office of the Vice President for Scientific University of Baghdad Iraq Quality Assurance and Academic Performance Department University of Baghdad Iraq School of Electronics and Computer Science University of Southampton Malaysia Johor Bahru Malaysia

The Software-Defined Networking (SDN) paradigm decouples the control and the data plane. One of the most significant challenges in this paradigm is SDN controller placement optimization, since improper placement may dramatically influence latency, load balancing, and network resilience. The paper proposes the Improved Harmony Search Algorithm (IHSA) as a new approach for the placement of SDN controllers. To overcome the disadvantages of conventional optimization methods like HSA, GA, and PSO, adaptive parameter tuning, dynamic harmony memory management, and updating rules for enhanced memory are incorporated into the IHSA. The complete simulations of IHSA over small, medium, and large-scale SDN topologies have shown its robust supremacy in performance compared to the benchmark algorithms, which provide up to 23.5% less latency along with significant improvements in load-balancing and convergence-time. The optimization results of IHSA are well supported by the statistical validity based on the p-values and confidence intervals. The algorithm is scalable, adaptive, and very efficient. Hence, it makes a more realistic solution for real-time and dynamic SDN environments. The results show that IHSA has the potential to improve network performance in latency-sensitive applications such as IoT, cloud computing, and telecommunications, thus opening up resilient and high-performance network infrastructures. This is a practical application of IHSA, and subsequently, the recommendation given through this study is for its integration with datasets and machine learning techniques from real world to further improve optimization. © 2025 The Author(s).

关键词： Resource allocation

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Workout Action Recognition in Video Streams Using an Attention Driven Residual DC-GRU Network

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computers, Materials & Continua 2024年第5期79卷 3067-3087页

作者： Arnab Dey Samit Biswas Dac-Nhuong Le Department of Computer Science and Technology Indian Institute of Engineering Science and TechnologyShibpurHowrah711103India Faculty of Information Technology Haiphong UniversityHaiphong180000Vietnam

Regular exercise is a crucial aspect of daily life, as it enables individuals to stay physically active, lowers thelikelihood of developing illnesses, and enhances life expectancy. The recognition of workout actions in videostreams holds significant importance in computer vision research, as it aims to enhance exercise adherence, enableinstant recognition, advance fitness tracking technologies, and optimize fitness routines. However, existing actiondatasets often lack diversity and specificity for workout actions, hindering the development of accurate recognitionmodels. To address this gap, the Workout Action Video dataset (WAVd) has been introduced as a significantcontribution. WAVd comprises a diverse collection of labeled workout action videos, meticulously curated toencompass various exercises performed by numerous individuals in different settings. This research proposes aninnovative framework based on the Attention driven Residual Deep Convolutional-Gated Recurrent Unit (ResDCGRU)network for workout action recognition in video streams. Unlike image-based action recognition, videoscontain spatio-temporal information, making the task more complex and challenging. While substantial progresshas been made in this area, challenges persist in detecting subtle and complex actions, handling occlusions,and managing the computational demands of deep learning approaches. The proposed ResDC-GRU Attentionmodel demonstrated exceptional classification performance with 95.81% accuracy in classifying workout actionvideos and also outperformed various state-of-the-art models. The method also yielded 81.6%, 97.2%, 95.6%, and93.2% accuracy on established benchmark datasets, namely HMDB51, Youtube Actions, UCF50, and UCF101,respectively, showcasing its superiority and robustness in action recognition. The findings suggest practicalimplications in real-world scenarios where precise video action recognition is paramount, addressing the persistingchallenges in the field. TheWAVd datas

关键词： Workout action recognition video stream action recognition residual network GRU attention

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DNACoder: a CNN-LSTM attention-based network for genomic sequence data compression

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Neural Computing and Applications 2024年第29期36卷 18363-18376页

作者： Sheena, K.S. Nair, Madhu S. Artificial Intelligence & amp Computer Vision Lab Department of Computer Science Cochin University of Science and Technology Kerala Kochi682022 India

Genomic sequencing has become increasingly prevalent, generating massive amounts of data and facing a significant challenge in long-term storage and transmission. A solution that reduces the storage and transfer requirements without compromising data integrity is needed. The effectiveness of neural networks has already been endorsed in tasks like image and speech compression. Adapting them to recognize the intricate patterns in genomic sequences could help to find more redundancies and reduce storage requirements. The proposed method, called DNACoder, leverages deep learning techniques to achieve significant compression ratios while preserving the essential information in genomic data and offers a high-performance compression for genomic sequences in any data format. The results of the experiments clearly demonstrate the effectiveness of the method and its potential applications in genomic data storage. Our proposed method improves compression by 21.1% on bits per base compared to existing compressors on the benchmarked dataset. By using a deep learning prediction model that is structured as a convolutional layer followed by an attention-based long short-term memory network, we propose a novel lossless and reference-free compression approach (DNACoder), which can also be utilized as a reference-based compressor. The experimental outcome on the tested data illustrates that the advocated compression algorithm’s CNN-LSTM model makes generalizations effectively for genomic sequence data and outperforms the state-of-the-art methods. © The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature 2024.

关键词： Long short-term memory

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